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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
48 Results for "
thrombotic diseases
" in MedChemExpress (MCE) Product Catalog:
Products (48)
48 Results for "thrombotic diseases" in MCE Product Catalog:
21
21 Publications Verification
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IOX2, a chemical probe, is a specific prolyl hydroxylase-2 (PHD2) inhibitor with IC50 of 22 nM. IOX2 regulates platelet function and arterial thrombosis by upregulating HIF-1α expression and inhibiting ROS production. IOX2 can be used in the study of thrombotic diseases .
12
12 Cited Publications
Synonyms: ALA free base; C18:3 (9Z,12Z,15Z) free base; C18:3 n-3 free base
Category:
Cardiovascular Disease Natural Products Labiatae Ulex europaeus L. Disease markers Plants Endogenous metabolite Disease Research Fields Cardiovascular System Disorder
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12
12 Cited Publications
Synonyms: ALA; C18:3 (9Z,12Z,15Z); C18:3 n-3
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α-Linolenic acid sodium (ALA; C18:3 (9Z,12Z,15Z); C18:3 n-3) is an essential fatty acid that cannot be synthesized by humans. α-Linolenic acid sodium can affect the process of thrombotic through the modulation of PI3K/Akt signaling. α-Linolenic acid sodium possess the anti-arrhythmic properties and is related to cardiovascular disease and cancer .
10
10 Cited Publications
Cat. No.: HY-P1929
CAS No.: 128270-60-0
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10
10 Cited Publications
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3
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1
1
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Cat. No.: HY-N0728S3
CAS No.: 287111-28-8
Cat. No.: HY-P99505
CAS No.: 2226654-05-1
Synonyms: COR-001; MEDI-5117; MEDI-5117; NN-6018; WBP-216
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Cat. No.: HY-W011690
CAS No.: 626-72-2
Category:
Cardiovascular Disease Ketones, Aldehydes, Acids Endogenous metabolite Disease Research Fields Inflammation/Immunology
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Cat. No.: HY-126356
CAS No.: 35418-59-8
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Cat. No.: HY-W089800
CAS No.: 18829-56-6
Synonyms: trans-2-Nonen-1-al
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Cat. No.: HY-N0728S
CAS No.: 145191-04-4
Cat. No.: HY-P3012
CAS No.: 107200-92-0
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Cathepsin G is a pH-dependent serine protease. Cathepsin G hydrolyzes diverse synthetic and protein substrates and remodels extracellular matrix. Cathepsin G exerts immunomodulatory effects via recruiting phagocytes, enhancing T cell motility, activating ERK1/2 and p38 MAPK signaling, and mediating PKCζ membrane translocation. Cathepsin G regulates inflammatory responses by cleaving inflammatory mediators. Cathepsin G participates in vascular regulation by converting angiotensin I to angiotensin II. Cathepsin G induces PAR4-dependent platelet activation, facilitates platelet-neutrophil aggregation, and mediates VITT-related NETosis, thrombus formation. Cathepsin G can be used for the research of immune thrombotic thrombocytopenia, cardiovascular disease, and select autoimmune and inflammatory diseases .
Cat. No.: HY-N2452
CAS No.: 956103-79-0
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Category:
Cardiovascular Disease Natural Products Ulex europaeus L. Plants Endogenous metabolite Microorganisms Labiatae Disease markers Disease Research Fields Cardiovascular System Disorder
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Cat. No.: HY-W004283R
CAS No.: 1002-84-2
Cat. No.: HY-W011690S
CAS No.: 182755-41-5
Research Areas:
DL-3-Indolylglycine is a compound intermediate and Amino acid derivative. DL-3-Indolylglycine can be used for the synthesis of serine protease inhibitors. DL-3-Indolylglycine is applicable to the research of thrombotic diseases .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
