1. Metabolic Enzyme/Protease
  2. Thrombin
  3. Inogatran

Inogatran (Synonyms: H-314-27)

Cat. No.: HY-19660
Handling Instructions

Inogatran is a synthetic thrombin inhibitor, developed for the possible treatment and prophylaxis of arterial and venous thrombotic diseases.

For research use only. We do not sell to patients.

Inogatran Chemical Structure

Inogatran Chemical Structure

CAS No. : 155415-08-0

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Description

Inogatran is a synthetic thrombin inhibitor, developed for the possible treatment and prophylaxis of arterial and venous thrombotic diseases.

In Vivo

Inogatran (0.075, 0.25, 0.75 mg/kg, i.v.) results in dose-dependent increases in activated partial thromboplastin time (aPTT), thrombin time (TT), and prothrombin time (PT) in a canine electrolytic injury model of venous thrombosis[1]. Inogatran dose-dependently inhibits thrombus formation, which is measured as an increase in time to occlusion (TTO) and a decrease in thrombus weight. Inogatran also improves vena caval blood flow and reduces the overall incidence of thrombotic occlusion in a rat model[2].

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
Molecular Weight

438.56

Formula

C₂₁H₃₈N₆O₄

CAS No.

155415-08-0

SMILES

O=C(O)CN[[email protected]](CC1CCCCC1)C(N2[[email protected]](C(NCCCNC(N)=N)=O)CCCC2)=O

Shipping

Room temperature in continental US; may vary elsewhere

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Product Name:
Inogatran
Cat. No.:
HY-19660
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Inogatran

Cat. No.: HY-19660