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Results for "

5-Amino-

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Aldehyde Oxidase (AO) (1) Amino Acid Derivatives (2) Amyloid-β (1) Antibiotic (1) Apoptosis (5) Autophagy (5) Bacterial (1) Biochemical Assay Reagents (10) Carbonic Anhydrase (2) CDK (1) DNA/RNA Synthesis (11) Drug Derivative (3) Drug Intermediate (10) Drug Isomer (1) E3 Ligase Ligand-Linker Conjugates (2) Endogenous Metabolite (13) Endothelin Receptor (1) Ephrin Receptor (1) GCGR (1) Glycosidase (1) GnRH Receptor (1) HIV (1) Influenza Virus (1) Insulin Receptor (1) Isotope-Labeled Compounds (11) Melanocortin Receptor (1) Mitochondrial Metabolism (1) Mitophagy (5) MOFs (8) NF-κB (2) Nucleoside Antimetabolite/Analog (8) Oxidative Phosphorylation (1) Parasite (1) Phosphoramidites (9) PROTAC Linkers (6) Proteasome (2) PSMA (2) Radionuclide-Drug Conjugates (RDCs) (4) Reactive Oxygen Species (ROS) (2) Reference Standards (11) Renin (1) Somatostatin Receptor (5) TNF Receptor (1)
By Research Areas:	Cancer (31) Cardiovascular Disease (4) Endocrinology (2) Infection (6) Inflammation/Immunology (4) Metabolic Disease (14) Neurological Disease (7)
Click Chemistry:	Azide (1)
Oligonucleotides:	Adenosine (1) Nucleoside Analogs (5) Uridine (3) Thymidine (1) Uracil (1) Other Phosphoramidite (9) Phosphoramidites (10)

112

Inhibitors & Agonists

Biochemical Assay Reagents

Peptides

Natural
Products

Isotope-Labeled Compounds

Click Chemistry

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N0305

5-Aminolevulinic acid hydrochloride Maximum Cited Publications 20 Publications Verification 5-ALA hydrochloride; δ-Aminolevulinic acid hydrochloride; 5-Amino-4-oxopentanoic acid hydrochloride	Reactive Oxygen Species (ROS)	Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
5-Aminolevulinic acid (5-ALA; δ-Aminolevulinic acid; 5-Amino-4-oxopentanoic acid) hydrochloride is an orally active heme precursor. 5-Aminolevulinic acid hydrochloride promotes aerobic energy metabolism and increases ATP levels by enhancing the activity of cytochrome c oxidase. 5-Aminolevulinic acid hydrochloride enhances LPS-induced proinflammatory cytokine production and gene activation, and restores the phagocytic activity and ROS generation capacity of neutrophils. 5-Aminolevulinic acid hydrochloride selectively accumulates protoporphyrin IX in tumor cells; as a photosensitizer and radiosensitizer, it induces ROS burst upon light or X-ray irradiation to inhibit tumor growth. 5-Aminolevulinic acid hydrochloride can be applied to the research of septic shock, melanoma, and cancer radiotherapy .

HY-W000450

5-Aminolevulinic acid Maximum Cited Publications 20 Publications Verification 5-ALA; δ-Aminolevulinic acid; 5-Amino-4-oxopentanoic acid	Reactive Oxygen Species (ROS)	Cardiovascular Disease Cancer
5-Aminolevulinic acid (5-ALA; δ-Aminolevulinic acid; 5-Amino-4-oxopentanoic acid) is an orally active heme precursor. 5-Aminolevulinic acid promotes aerobic energy metabolism and increases ATP levels by enhancing the activity of cytochrome c oxidase. 5-Aminolevulinic acid enhances LPS-induced proinflammatory cytokine production and gene activation, and restores the phagocytic activity and ROS generation capacity of neutrophils. 5-Aminolevulinic acid selectively accumulates protoporphyrin IX in tumor cells; as a photosensitizer and radiosensitizer, it induces ROS burst upon light or X-ray irradiation to inhibit tumor growth. 5-Aminolevulinic acid can be applied to the research of septic shock, melanoma, and cancer radiotherapy .

HY-41461

5-Amino-3H-imidazole-4-Carboxamide 1 Publications Verification 5-Aminoimidazole-4-carboxamide; AICA	Endogenous Metabolite	Others
5-Amino-3H-imidazole-4-Carboxamide (5-Aminoimidazole-4-carboxamide; AICA) is an important precursor for the synthesis of purines in general and of the nucleobases adenine and guanine in particular .

HY-132248

C5 Lenalidomide Lenalidomide 5'-amine	Drug Derivative TNF Receptor	Inflammation/Immunology
C5 Lenalidomide is a 5-amino-substituted Thalidomide (HY-14658) analog. C5 Lenalidomide inhibits LPS (HY-D1056)-stimulated TNF-α production .

HY-W001023

5-Amino-8-hydroxyquinoline 5A8HQ; 5AHQ	Proteasome NF-κB	Cancer
5-Amino-8-hydroxyquinoline (5A8HQ; 5AHQ) is an orally active non-competitive 20S proteasome inhibitor. 5-Amino-8-hydroxyquinoline can inhibit NF-κB activity and induce cancer cells death and shows low cytotoxicity towards normal hematopoietic cells. 5-Amino-8-hydroxyquinoline can be used for the research of cancer, such as leukemia .

HY-P2336A

CCZ01048 TFA 3 Publications Verification	Melanocortin Receptor	Cancer
CCZ01048 TFA, a α-MSH analogue, exhibits high binding affinity to melanocortin 1 receptor (MC1R) with a K_i of 0.31 nM. CCZ01048 TFA shows rapid internalization into B16F10 melanoma cells and high in vivo stability. CCZ01048 TFA is a promising candidate for PET imaging of malignant melanoma .

HY-W012971

5-Amino-1-pentanol	Biochemical Assay Reagents	Others
5-Amino-1-pentanol is a linker containing a hydroxyl group and amine group. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. The amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc.

HY-41461A

5-Amino-3H-imidazole-4-carboxamide hydrochloride 1 Publications Verification 5-Aminoimidazole-4-carboxamide hydrochloride; AICA hydrochloride	Endogenous Metabolite	Others
5-Amino-3H-imidazole-4-Carboxamide (AICA) hydrochloride is an important precursor for the synthesis of purines in general and of the nucleobases adenine and guanine in particular .

HY-131818

5'-Amino-5'-deoxyadenosine NH2dAdo; Nsc 238990	Nucleoside Antimetabolite/Analog	Cancer
5'-Amino-5'-deoxyadenosine (NH2dAdo; Nsc 238990) is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-W011203

*(S)-2-(5-Amino-2-(((benzyloxy)carbonyl)amino)-5-oxopentanamido)acetic acid*	Amino Acid Derivatives	Others
(S)-2-(5-Amino-2-(((benzyloxy)carbonyl)amino)-5-oxopentanamido)acetic acid is a Glycine (HY-Y0966) derivative .

HY-W074975

CL 5343 5-Amino-1,3,4-thiadiazole-2-sulfonamide	Carbonic Anhydrase	Cancer
CL 5343 (5-Amino-1,3,4-thiadiazole-2-sulfonamide) is a selective inhibitor of carbonic anhydrase B (HCA-B) and isoforms I, II, IV, and VII. CL 5343 has a K_i of 7.9 nM for hCA II. CL 5343 acts as a CA9 ligand to achieve targeted delivery of maytansine to the cell membrane of SKRC52 renal cancer cells. CL 5343 is useful in the development of therapeutics for diseases associated with CA overactivity, such as glaucoma, epilepsy, and cancer .

HY-66048

5-Amino-2-picoline 5-Amino-2-methylpyridine	Biochemical Assay Reagents Drug Intermediate	Others
5-Amino-2-picoline (5-Amino-2-methylpyridine) is a biochemical reagent that can be used as a biological material or organic compound for life science related research. 5-Amino-2-picoline is also an important intermediate and can be used in the synthesis of other active compounds .

HY-W057815

*cis-5-Amino-2-Boc-hexahydro-cyclopenta[c]pyrrole*	PROTAC Linkers	Cancer
cis-5-Amino-2-Boc-hexahydro-cyclopenta[c]pyrrole is a PROTAC linker that can be used in the synthesis of PROTACs.

HY-78055

*2-(((3aR,4S,6R,6aS)-6-((5-Amino-6-chloro-2-(propylthio)pyrimidin-4-yl)amino)-2,2-dimethyltetrahydro-3aH-cyclopenta[d][1,3]dioxol-4-yl)oxy)ethanol*	Drug Intermediate	Others
2-(((3aR,4S,6R,6aS)-6-((5-Amino-6-chloro-2-(propylthio)pyrimidin-4-yl)amino)-2,2-dimethyltetrahydro-3aH-cyclopenta[d][1,3]dioxol-4-yl)oxy)ethanol is a drug intermediate for synthesis of various active compounds.

HY-140194

Amino-PEG5-Boc	PROTAC Linkers	Cancer
Amino-PEG5-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .

HY-130447

Amino-PEG5-amine	PROTAC Linkers	Cancer
Amino-PEG5-amine is a PEG-based (5 units) PROTAC linker can be used in the synthesis of PROTACs.

HY-N0305R

5-Aminolevulinic acid hydrochloride (Standard) 10+ Cited Publications 5-ALA hydrochloride (Standard); δ-Aminolevulinic acid hydrochloride (Standard); 5-Amino-4-oxopentanoic acid hydrochloride (Standard)	Autophagy Endogenous Metabolite Apoptosis Mitophagy Reference Standards	Metabolic Disease Cancer
5-Aminolevulinic acid (hydrochloride) (Standard) is the analytical standard of 5-Aminolevulinic acid (hydrochloride). This product is intended for research and analytical applications. 0

HY-P10341

ZP3022	GCGR	Metabolic Disease
ZP3022 is a dual agonist of glucagon-like peptide-1 (GLP-1) and gastrin that has the ability to sustainably improve glycemic control. Additionally, ZP3022 can effectively increase β-cell mass, promote β-cell proliferation, and enhance the function of pancreatic islets. ZP3022 can be used in anti-diabetic research .

HY-W001994

5-Amino-2-methoxypyridine	Biochemical Assay Reagents	Others
5-Amino-2-methoxypyridine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-77822

5-Amino-2-chlorobenzotrifluoride	Biochemical Assay Reagents	Others
5-Amino-2-chlorobenzotrifluoride is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-W011983

5-Amino-2-((tert-butoxycarbonyl)amino)-5-oxopentanoic acid	Amino Acid Derivatives	Others
5-Amino-2-((tert-butoxycarbonyl)amino)-5-oxopentanoic acid is a glutamine derivative .

HY-154945

*N-(5-Amino-1-ribosyl-4-imidazolecarbonyl)-L-aspartic acid*	Endogenous Metabolite	Metabolic Disease
N-(5-Amino-1-ribosyl-4-imidazolecarbonyl)-L-aspartic acid is a nucleoside metabolite .

HY-32854

4-Bromo-3-(trifluoromethyl)aniline 5-Amino-2-bromobenzotrifluoride	Drug Intermediate	Neurological Disease Inflammation/Immunology
4-Bromo-3-(trifluoromethyl)aniline (5-Amino-2-bromobenzotrifluoride) can be used for synthesis of AUY954 (HY-119221) (a S1P1 receptor agonist) .

HY-75318

*(5-Amino-2-butylbenzofuran-3-yl)(4-(3-(dibutylamino)propoxy)phenyl)methanone* Dronedarone impurity A	Drug Intermediate	Others
(5-Amino-2-butylbenzofuran-3-yl)(4-(3-(dibutylamino)propoxy)phenyl)methanone (Dronedarone impurity A) is a drug intermediate for synthesis of various active compounds.

HY-W613598

*tert-Butyl (S)-5-amino-4-(4-hydroxy-1-oxoisoindolin-2-yl)-5-oxopentanoate*	E3 Ligase Ligand-Linker Conjugates	Cancer
tert-Butyl (S)-5-amino-4-(4-hydroxy-1-oxoisoindolin-2-yl)-5-oxopentanoate is an E3 ligase ligand-linker conjugate containing a CRBN-based ligand and linker, which can be used to synthesize PROTAC.

HY-N0305S

5-Aminolevulinic acid-15N hydrochloride 5-ALA-15N hydrochloride; δ-Aminolevulinic acid-15N hydrochloride; 5-Amino-4-oxopentanoic acid-15N hydrochloride	Isotope-Labeled Compounds Autophagy Mitophagy Endogenous Metabolite Apoptosis	Metabolic Disease Cancer
5-Aminolevulinic acid- ¹⁵N (hydrochloride) is the ¹⁵N-labeled 5-Aminolevulinic acid (hydrochloride). 5-Aminolevulinic acid hydrochloride (5-ALA hydrochloride) is an intermediate in heme biosynthesis in the body and the universal precursor of tetrapyrroles.

HY-W749251

5-Aminolevulinic acid-13C2,15N hydrochloride 5-ALA-13C2,15N hydrochloride; δ-Aminolevulinic acid-13C2,15N hydrochloride; 5-Amino-4-oxopentanoic acid-13C2,15N hydrochloride	Endogenous Metabolite Isotope-Labeled Compounds	Others
5-Aminolevulinic acid- ¹³C₂, ¹⁵N (5-ALA- ¹³C₂, ¹⁵N; δ-Aminolevulinic acid- ¹³C₂, ¹⁵N) is ¹³C- and ¹⁵N-labeled 5-Aminolevulinic acid (HY-W000450) .

HY-W007272

5-Amino-2,4-difluorophenol	Drug Intermediate	Others
5-Amino-2,4-difluorophenol is a drug intermediate for synthesis of various active compounds.

HY-I0147

5-Amino-2,4-di-tert-butylphenyl methyl carbonate	Drug Intermediate	Others
5-Amino-2,4-di-tert-butylphenyl methyl carbonate is a drug intermediate for synthesis of various active compounds.

HY-W702789

*N-(5-Amino-1-ribosyl-4-imidazolecarbonyl)-L-aspartic acid disodium*	Endogenous Metabolite	Metabolic Disease
N-(5-Amino-1-ribosyl-4-imidazolecarbonyl)-L-aspartic acid disodium is a nucleoside metabolite .

HY-W106292

5'-Amino-[1,1':3',1''-terphenyl]-4,4''-dicarboxylic acid	MOFs	Others
5'-Amino-[1,1':3',1''-terphenyl]-4,4''-dicarboxylic acid is a metal-organic framework (MOF).

HY-70065

4-Chloro-3-methylisoxazol-5-amine 5-Amino-4-chloro-3-methylisoxazole	Drug Intermediate	Others
4-Chloro-3-methylisoxazol-5-amine (5-Amino-4-chloro-3-methylisoxazole) is a drug intermediate for synthesis of various active compounds.

HY-43367

5-Amino-1,3-dimethyl-6-(3-propoxyphenoxy)-1H-benzo[d]imidazol-2(3H)-one	Drug Intermediate	Others
5-Amino-1,3-dimethyl-6-(3-propoxyphenoxy)-1H-benzo[d]imidazol-2(3H)-one is a drug intermediate for synthesis of various active compounds.

HY-77931

*(R)-1-[5-Amino-2-(2-benzyloxy-1,1-dimethyl-ethyl)-6-fluoro-indol-1-yl]-3-benzyloxy-propan-2-ol* VX-661 intermediate	Drug Intermediate	Others
(R)-1-[5-Amino-2-(2-benzyloxy-1,1-dimethyl-ethyl)-6-fluoro-indol-1-yl]-3-benzyloxy-propan-2-ol (VX-661 intermediate) is a drug intermediate for synthesis of various active compounds.

HY-135916

Biotin-C5-amino-C5-amino	PROTAC Linkers	Cancer
Biotin-C5-amino-C5-amino is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs .

HY-W025736

5-Amino-2-methoxyphenol	Drug Isomer	Neurological Disease Inflammation/Immunology
5-Amino-2-methoxyphenol is a phenolic regioisomer. 5-Amino-2-methoxyphenol produces dose-dependent antinociception in the mouse formalin test, with its second-phase effect being mechanistically dependent on both FAAH and TRPV1. 5-Amino-2-methoxyphenol can be used for antinociception research .

HY-65254

5-Amino-2-fluoropyridine	Biochemical Assay Reagents Drug Intermediate	Others
5-Amino-2-fluoropyridine is a fluorinated heterocyclic compound, which can be used for the synthesis of other active compounds .

HY-33849

5-Amino-1H-indazole	Biochemical Assay Reagents	Others
5-Amino-1H-indazole is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-P11004

A3-APO	Bacterial Antibiotic	Infection
A3-APO is an antimicrobial peptide. A3-APO has a significant antimicrobial activity by a dual mode of action with both membrane disintegration and intracellular target inhibition. A3-APO can deactivate bacterial toxins and increase the expression of anti-inflammatory cytokines (such as IL-4 and IL-10), without antimicrobial resistance. A3-APO accelerates burn wounds healing in mice infection model of Acinetobacter baumannii and Staphylococcus aureus .

HY-19844

ANA-975	Drug Derivative Aldehyde Oxidase (AO)	Infection
ANA975, 5-amino-3-β -D-ribofuranosyl-3H-thiazolo[4,5-d]pyrimidin-2-one derivative, is an oral prodrug of the TLR-7 agonist Isatoribine (HY-13655A). ANA975 is converted to Isatoribine via a combined mechanism of hydrolysis by esterases and oxidation by aldehyde oxidase. ANA975 can be used in the research of hepatitis C virus infection .

HY-P10472

Azaline B	GnRH Receptor	Endocrinology
Azaline B is an antagonist for gonadotropin-releasing hormone (GnRH) with IC₅₀ of 1.37 nM, Azaline B can be used in research of sex hormone-related pathological states, ovulation induction and male contraception .

HY-P4757

N1-Glutathionyl-spermidine disulfide	Parasite	Others
N1-Glutathionyl-spermidine disulfide is a substrate of trypanothione reductase .

HY-N0305S1

5-Aminolevulinic acid-d2 hydrochloride 5-ALA-d2 hydrochloride; δ-Aminolevulinic acid-d2 hydrochloride; 5-Amino-4-oxopentanoic acid-d2 hydrochloride	Isotope-Labeled Compounds Autophagy Mitophagy Endogenous Metabolite Apoptosis	Metabolic Disease Cancer
5-Aminolevulinic acid-d₂ (hydrochloride) is deuterium labeled 5-Aminolevulinic acid (hydrochloride).

HY-N0305S3

5-Aminolevulinic acid-13C-1 hydrochloride 5-ALA-13C-1 hydrochloride; δ-Aminolevulinic acid-13C-1 hydrochloride; 5-Amino-4-oxopentanoic acid-13C-1 hydrochloride	Apoptosis Autophagy Mitophagy Endogenous Metabolite	Metabolic Disease
5-Aminolevulinic acid- ¹³C-1 (5-ALA- ¹³C-1) hydrochloride is the ¹³C labeled 5-Aminolevulinic acid hydrochloride . 5-Aminolevulinic acid hydrochloride (5-ALA hydrochloride) is an intermediate in heme biosynthesis in the body and the universal precursor of tetrapyrroles .

HY-W000450S

5-Aminolevulinic acid-13C 5-ALA-¹³C; δ-Aminolevulinic acid-¹³C; 5-Amino-4-oxopentanoic acid-¹³C	Isotope-Labeled Compounds Endogenous Metabolite	Cardiovascular Disease
5-Aminolevulinic acid- ¹³C is the ¹³C-labeled 5-Aminolevulinic acid. 5-Aminolevulinic acid (5-ALA) is a non-protein amino acid that plays a rate-limiting role in heme biosynthesis.

HY-156291

XSJ2-46	DNA/RNA Synthesis Influenza Virus	Infection
XSJ2-46, 5'-amino NI analog, is an antiviral agent. XSJ2-46 has anti-Zika virus activity. XSJ2-46 exhibits reasonable inhibition of RNA-dependent RNA polymerases (RdRp) with an IC₅₀ value of 8.78 μM .

HY-77822R

5-Amino-2-chlorobenzotrifluoride (Standard)	Biochemical Assay Reagents Reference Standards	Others
5-Amino-2-chlorobenzotrifluoride (Standard) is the analytical standard of 5-Amino-2-chlorobenzotrifluoride. This product is intended for research and analytical applications. 5-Amino-2-chlorobenzotrifluoride is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-171832

5'-Amino-5'-deoxyuridine	DNA/RNA Synthesis	Infection Cancer
5'-Amino-5'-deoxyuridine is a nucleoside analog that can be used in nucleic acid synthesis .

HY-149160

5′-Amino-5′-deoxythymidine	Nucleoside Antimetabolite/Analog	Cancer
5′-Amino-5′-deoxythymidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-W015858R

5-Amino-2-methylphenol (Standard) 3-Hydroxy-4-methylaniline (Standard)	Reference Standards
5-Amino-2-methylphenol (Standard) is the analytical standard of 5-Amino-2-methylphenol. This product is intended for research and analytical applications.

Cat. No.	Product Name	Type

HY-41461A

5-Amino-3H-imidazole-4-carboxamide hydrochloride 1 Publications Verification 5-Aminoimidazole-4-carboxamide hydrochloride; AICA hydrochloride	Biochemical Assay Reagents
5-Amino-3H-imidazole-4-Carboxamide (AICA) hydrochloride is an important precursor for the synthesis of purines in general and of the nucleobases adenine and guanine in particular .

HY-66048

5-Amino-2-picoline 5-Amino-2-methylpyridine	Biochemical Assay Reagents
5-Amino-2-picoline (5-Amino-2-methylpyridine) is a biochemical reagent that can be used as a biological material or organic compound for life science related research. 5-Amino-2-picoline is also an important intermediate and can be used in the synthesis of other active compounds .

HY-W001994

5-Amino-2-methoxypyridine	Biochemical Assay Reagents
5-Amino-2-methoxypyridine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-77822

5-Amino-2-chlorobenzotrifluoride	Biochemical Assay Reagents
5-Amino-2-chlorobenzotrifluoride is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-W025736

5-Amino-2-methoxyphenol	Biochemical Assay Reagents
5-Amino-2-methoxyphenol is a phenolic regioisomer. 5-Amino-2-methoxyphenol produces dose-dependent antinociception in the mouse formalin test, with its second-phase effect being mechanistically dependent on both FAAH and TRPV1. 5-Amino-2-methoxyphenol can be used for antinociception research .

HY-65254

5-Amino-2-fluoropyridine	Biochemical Assay Reagents
5-Amino-2-fluoropyridine is a fluorinated heterocyclic compound, which can be used for the synthesis of other active compounds .

HY-33849

5-Amino-1H-indazole	Biochemical Assay Reagents
5-Amino-1H-indazole is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-77822R

5-Amino-2-chlorobenzotrifluoride (Standard)	Biochemical Assay Reagents
5-Amino-2-chlorobenzotrifluoride (Standard) is the analytical standard of 5-Amino-2-chlorobenzotrifluoride. This product is intended for research and analytical applications. 5-Amino-2-chlorobenzotrifluoride is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-41461AR

5-Amino-3H-imidazole-4-carboxamide hydrochloride (Standard)

5-Aminoimidazole-4-carboxamide hydrochloride (Standard); AICA hydrochloride (Standard)

Biochemical Assay Reagents

5-Amino-3H-imidazole-4-carboxamide (hydrochloride) (Standard) is the analytical standard of 5-Amino-3H-imidazole-4-carboxamide hydrochloride (HY-41461A). This product is intended for research and analytical applications. 5-Amino-3H-imidazole-4-Carboxamide (AICA) hydrochloride is an important precursor for the synthesis of purines in general and of the nucleobases adenine and guanine in particular .

HY-W777089

Benzyl 5-amino-5-deoxy-2,3-O-isopropyl-α-D-mannofuranoside

Biochemical Assay Reagents

Benzyl 5-amino-5-deoxy-2,3-O-isopropyl-α-D-mannofuranoside is a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It involves carbohydrate chemistry, enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans in biological systems. This field is closely related to basic research, biomedicine, and biotechnology .

HY-W777090

Benzyl 5-amino-5-deoxy-2,3-O-isopropylidene-6-O-trityl-α-D-mannofuranoside

Biochemical Assay Reagents

Benzyl 5-amino-5-deoxy-2,3-O-isopropylidene-6-O-trityl-α-D-mannofuranoside is a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It involves carbohydrate chemistry, enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans in biological systems. This field is closely related to basic research, biomedicine, and biotechnology .

Cat. No.	Product Name	Target	Research Area

HY-P4070

Insulin icodec	Insulin Receptor	Metabolic Disease
Insulin icodec is an Insulin (HY-P0035) analog that strongly but reversibly binds to albumin. Insulin icodec has long plasma half-life. Insulin icodec modulates insulin receptor activity, controls blood glucose levels, reduces HbA_1c levels, and binds reversibly to human serum albumin. Insulin icodec can be used for the research of type 2 diabetes mellitus .

HY-105055

Didemnin B	Peptides	Cancer
Didemnin B is a depsipeptide extracted from the marine tunicate Trididemnin cyanophorum. Didemnin B can be used for the research of cancer .

HY-P5362

NODAGA-LM3	Radionuclide-Drug Conjugates (RDCs) Somatostatin Receptor	Neurological Disease Cancer
NODAGA-LM3 is a ligand that can cross the blood-brain barrier and targets somatostatin receptor SSTR2 with high affinity (IC₅₀ = 1.3 nM). NODAGA-LM3 does not trigger the internalization of SSTR2 and can inhibit agonist-induced internalization processes. NODAGA-LM3 shows low uptake in normal tissues such as the liver and spleen, but high uptake in the lungs and blood pool. ⁶⁸Ga-labeled NODAGA-LM3 can serve as a PET imaging agent for well-differentiated neuroendocrine tumors, and is applied in studies related to small cell lung cancer and well-differentiated neuroendocrine tumors .

HY-P2336A

CCZ01048 TFA 3 Publications Verification	Melanocortin Receptor	Cancer
CCZ01048 TFA, a α-MSH analogue, exhibits high binding affinity to melanocortin 1 receptor (MC1R) with a K_i of 0.31 nM. CCZ01048 TFA shows rapid internalization into B16F10 melanoma cells and high in vivo stability. CCZ01048 TFA is a promising candidate for PET imaging of malignant melanoma .

HY-P5481

DABCYL-LPETG-EDANS	Peptides	Others
DABCYL-LPETG-EDANS is a biological active peptide. (This 5-amino acid peptide is a sortase substrate, C-terminal sorting signal. Sortase cleaves surface proteins at the LPXTG motif and catalyzes the formation of an amide bond between the carboxyl group of threonine and the amino group of cell-wall crossbridges. Sortases are a family of Gram-positive transpeptidases responsible for anchoring surface protein virulence factors to the peptidoglycan cell wall layer. Cleavage of this FRET substrate by sortase reveals the fluorescent signal, Abs/Em = 340/490 nm.)

HY-W011203

*(S)-2-(5-Amino-2-(((benzyloxy)carbonyl)amino)-5-oxopentanamido)acetic acid*	Amino Acid Derivatives	Others
(S)-2-(5-Amino-2-(((benzyloxy)carbonyl)amino)-5-oxopentanamido)acetic acid is a Glycine (HY-Y0966) derivative .

HY-P10341

ZP3022	GCGR	Metabolic Disease
ZP3022 is a dual agonist of glucagon-like peptide-1 (GLP-1) and gastrin that has the ability to sustainably improve glycemic control. Additionally, ZP3022 can effectively increase β-cell mass, promote β-cell proliferation, and enhance the function of pancreatic islets. ZP3022 can be used in anti-diabetic research .

HY-W011983

5-Amino-2-((tert-butoxycarbonyl)amino)-5-oxopentanoic acid	Amino Acid Derivatives	Others
5-Amino-2-((tert-butoxycarbonyl)amino)-5-oxopentanoic acid is a glutamine derivative .

HY-P11004

A3-APO	Bacterial Antibiotic	Infection
A3-APO is an antimicrobial peptide. A3-APO has a significant antimicrobial activity by a dual mode of action with both membrane disintegration and intracellular target inhibition. A3-APO can deactivate bacterial toxins and increase the expression of anti-inflammatory cytokines (such as IL-4 and IL-10), without antimicrobial resistance. A3-APO accelerates burn wounds healing in mice infection model of Acinetobacter baumannii and Staphylococcus aureus .

HY-P10472

Azaline B	GnRH Receptor	Endocrinology
Azaline B is an antagonist for gonadotropin-releasing hormone (GnRH) with IC₅₀ of 1.37 nM, Azaline B can be used in research of sex hormone-related pathological states, ovulation induction and male contraception .

HY-P4757

N1-Glutathionyl-spermidine disulfide	Parasite	Others
N1-Glutathionyl-spermidine disulfide is a substrate of trypanothione reductase .

HY-P11243

EphA4 agonist compound 23	Ephrin Receptor	Neurological Disease
EphA4 agonist compound 23 is a novel EphA4 agonist peptide mimic. EphA4 agonist compound 23 exhibits high affinity, high selectivity, and significant receptor activation ability. EphA4 agonist compound 23 is commonly used in the study of neurodegenerative diseases .

HY-P2434

AP102	Somatostatin Receptor	Neurological Disease Metabolic Disease Cancer
AP102 is a dual *SSTR2/SSTR5*-specific somatostatin analog (SSA). AP102 is a disulfide-bridged octapeptide SSA containing synthetic iodinated amino acids. AP102 binds with subnanomolar affinity to SSTR2 and *SSTR5* (IC₅₀: 0.63 and 0.65 nM, respectively). AP102 does not bind to SSTR1 or SSTR3. AP102 can be used for acromegaly and neuroendocrine tumors research .

HY-P5362A

NODAGA-LM3 TFA	Radionuclide-Drug Conjugates (RDCs) Somatostatin Receptor	Cancer
NODAGA-LM3 TFA is a ligand that can cross the blood-brain barrier and targets somatostatin receptor SSTR2 with high affinity (IC₅₀ = 1.3 nM). NODAGA-LM3 TFA does not trigger the internalization of SSTR2 and can inhibit agonist-induced internalization processes. NODAGA-LM3 TFA shows low uptake in normal tissues such as the liver and spleen, but high uptake in the lungs and blood pool. ⁶⁸Ga-labeled NODAGA-LM3 TFA can serve as a PET imaging agent for well-differentiated neuroendocrine tumors, and is applied in studies related to small cell lung cancer and well-differentiated neuroendocrine tumors .

HY-105168

TAK 044	Endothelin Receptor	Cardiovascular Disease
TAK 044 is an antagonist of Endothelin Receptor. TAK 044 strongly inhibits ET-induced deterioration in various animal models. TAK 044 can be used in study ET-related diseases such as acute myocardial infarction,acute renal failure, acute hepatic malfunction, and subarachnoid hemorrhage .

HY-P2075

EMD 55068	Renin	Endocrinology
EMD 55068 is a renin antagonist. EMD 55068 inhibits the uptake of taurocholate .

HY-P10876

mcK6A1	Amyloid-β	Neurological Disease
mcK6A1 is an inhibitor for the aggregation of amyloid-β (Aβ), that selectively binds to the 16KLVFFA21 segment of Aβ42, forms an extended β-folded structure, and inhibits the formation of Aβ42 oligomers. mcK6A1 can be used in research of Alzheimer's disease and other amyloid-related diseases .

HY-P11488

JR11-PEG3-DOTA-PSMA-03	Radionuclide-Drug Conjugates (RDCs) Somatostatin Receptor PSMA	Cancer
JR11-PEG3-DOTA-PSMA-03 (Compound 2) is an RDC-related compound containing the chelating agent DOTA (HY-W053583), the JR11 peptide (SSTR2 antagonist), and the PSMA ligand. JR11-PEG3-DOTA-PSMA-03 shows SSTR2-binding affinities and PSMA-binding affinities, with IC₅₀ s of 94.0 nM, 81.8 nM, respectively. JR11-PEG3-DOTA-PSMA-03 can be radiolabeled with [ ⁶⁸Ga]. [ ⁶⁸Ga] radiolabeled JR11-PEG3-DOTA-PSMA-03 can be used in diagnostic studies of neuroendocrine differentiated prostate cancer .

HY-P11485

JR11-PEG3-HBED-CC-PSMA-03	Radionuclide-Drug Conjugates (RDCs) Somatostatin Receptor PSMA	Cancer
JR11-PEG3-HBED-CC-PSMA-03 (Compound 1) is an RDC-related compound containing the chelating agent HBED-CC, the JR11 peptide (SSTR2 antagonist), and the PSMA ligand. JR11-PEG3-HBED-CC-PSMA-03 shows SSTR2-binding affinities and PSMA-binding affinities, with IC₅₀ s of 59.2 nM, 57.0 nM, respectively. JR11-PEG3-HBED-CC-PSMA-03 can be radiolabeled with [ ⁶⁸Ga]. [ ⁶⁸Ga] radiolabeled JR11-PEG3-HBED-CC-PSMA-03 can be used in diagnostic studies of neuroendocrine differentiated prostate cancer .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N0305

5-Aminolevulinic acid hydrochloride Maximum Cited Publications 20 Publications Verification 5-ALA hydrochloride; δ-Aminolevulinic acid hydrochloride; 5-Amino-4-oxopentanoic acid hydrochloride	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Endogenous metabolite Disease Research Fields Cancer	Reactive Oxygen Species (ROS)
5-Aminolevulinic acid (5-ALA; δ-Aminolevulinic acid; 5-Amino-4-oxopentanoic acid) hydrochloride is an orally active heme precursor. 5-Aminolevulinic acid hydrochloride promotes aerobic energy metabolism and increases ATP levels by enhancing the activity of cytochrome c oxidase. 5-Aminolevulinic acid hydrochloride enhances LPS-induced proinflammatory cytokine production and gene activation, and restores the phagocytic activity and ROS generation capacity of neutrophils. 5-Aminolevulinic acid hydrochloride selectively accumulates protoporphyrin IX in tumor cells; as a photosensitizer and radiosensitizer, it induces ROS burst upon light or X-ray irradiation to inhibit tumor growth. 5-Aminolevulinic acid hydrochloride can be applied to the research of septic shock, melanoma, and cancer radiotherapy .

HY-W000450

5-Aminolevulinic acid Maximum Cited Publications 20 Publications Verification 5-ALA; δ-Aminolevulinic acid; 5-Amino-4-oxopentanoic acid	Cardiovascular Disease Structural Classification Classification of Application Fields Amino acids Endogenous metabolite Human Gut Microbiota Metabolites Immune System Disorder Microorganisms Ketones, Aldehydes, Acids Disease markers Disease Research Fields Source Classification Cancer	Reactive Oxygen Species (ROS)
5-Aminolevulinic acid (5-ALA; δ-Aminolevulinic acid; 5-Amino-4-oxopentanoic acid) is an orally active heme precursor. 5-Aminolevulinic acid promotes aerobic energy metabolism and increases ATP levels by enhancing the activity of cytochrome c oxidase. 5-Aminolevulinic acid enhances LPS-induced proinflammatory cytokine production and gene activation, and restores the phagocytic activity and ROS generation capacity of neutrophils. 5-Aminolevulinic acid selectively accumulates protoporphyrin IX in tumor cells; as a photosensitizer and radiosensitizer, it induces ROS burst upon light or X-ray irradiation to inhibit tumor growth. 5-Aminolevulinic acid can be applied to the research of septic shock, melanoma, and cancer radiotherapy .

HY-41461

5-Amino-3H-imidazole-4-Carboxamide 1 Publications Verification 5-Aminoimidazole-4-carboxamide; AICA	Structural Classification Natural Products Classification of Application Fields Other Diseases Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
5-Amino-3H-imidazole-4-Carboxamide (5-Aminoimidazole-4-carboxamide; AICA) is an important precursor for the synthesis of purines in general and of the nucleobases adenine and guanine in particular .

HY-105055

Didemnin B	Natural Products Animals Classification of Application Fields Marine natural products Other marine organisms Disease Research Fields Source Classification Cancer	Others
Didemnin B is a depsipeptide extracted from the marine tunicate Trididemnin cyanophorum. Didemnin B can be used for the research of cancer .

HY-41461A

5-Amino-3H-imidazole-4-carboxamide hydrochloride 1 Publications Verification 5-Aminoimidazole-4-carboxamide hydrochloride; AICA hydrochloride	Microorganisms Source Classification	Endogenous Metabolite
5-Amino-3H-imidazole-4-Carboxamide (AICA) hydrochloride is an important precursor for the synthesis of purines in general and of the nucleobases adenine and guanine in particular .

HY-N0305R

5-Aminolevulinic acid hydrochloride (Standard) 10+ Cited Publications 5-ALA hydrochloride (Standard); δ-Aminolevulinic acid hydrochloride (Standard); 5-Amino-4-oxopentanoic acid hydrochloride (Standard)	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Endogenous metabolite Disease Research Fields Source Classification Cancer	Autophagy Endogenous Metabolite Apoptosis Mitophagy Reference Standards
5-Aminolevulinic acid (hydrochloride) (Standard) is the analytical standard of 5-Aminolevulinic acid (hydrochloride). This product is intended for research and analytical applications. 0

HY-41461R

5-Amino-3H-imidazole-4-Carboxamide (Standard) 5-Aminoimidazole-4-carboxamide (Standard); AICA (Standard)	Structural Classification Natural Products Endogenous metabolite Source Classification	Reference Standards Endogenous Metabolite
5-Amino-3H-imidazole-4-Carboxamide (Standard) is the analytical standard of 5-Amino-3H-imidazole-4-Carboxamide. This product is intended for research and analytical applications. 5-Amino-3H-imidazole-4-Carboxamide (AICA) is an important precursor for the synthesis of purines in general and of the nucleobases adenine and guanine in particular.

HY-41461AR

5-Amino-3H-imidazole-4-carboxamide hydrochloride (Standard) 5-Aminoimidazole-4-carboxamide hydrochloride (Standard); AICA hydrochloride (Standard)	Microorganisms Source Classification	Reference Standards Endogenous Metabolite
5-Amino-3H-imidazole-4-carboxamide (hydrochloride) (Standard) is the analytical standard of 5-Amino-3H-imidazole-4-carboxamide hydrochloride (HY-41461A). This product is intended for research and analytical applications. 5-Amino-3H-imidazole-4-Carboxamide (AICA) hydrochloride is an important precursor for the synthesis of purines in general and of the nucleobases adenine and guanine in particular .

HY-180757

*(S)-5-Amino-3-oxohexanoic acid*	Structural Classification Ketones, Aldehydes, Acids Endogenous metabolite Source Classification	Nucleoside Antimetabolite/Analog
(S)-5-Amino-3-oxohexanoic acid is a nucleoside metabolite.

HY-W341825

5-Amino-1H-imidazole-4-carboxylic acid	Structural Classification Ketones, Aldehydes, Acids Endogenous metabolite Source Classification	Nucleoside Antimetabolite/Analog
5-Amino-1H-imidazole-4-carboxylic acid is a nucleoside metabolite.

Cat. No.	Product Name	Chemical Structure

HY-N0305S

5-Aminolevulinic acid-15N hydrochloride
5-Aminolevulinic acid- ¹⁵N (hydrochloride) is the ¹⁵N-labeled 5-Aminolevulinic acid (hydrochloride). 5-Aminolevulinic acid hydrochloride (5-ALA hydrochloride) is an intermediate in heme biosynthesis in the body and the universal precursor of tetrapyrroles.

HY-W749251

5-Aminolevulinic acid-13C2,15N hydrochloride
5-Aminolevulinic acid- ¹³C₂, ¹⁵N (5-ALA- ¹³C₂, ¹⁵N; δ-Aminolevulinic acid- ¹³C₂, ¹⁵N) is ¹³C- and ¹⁵N-labeled 5-Aminolevulinic acid (HY-W000450) .

HY-N0305S1

5-Aminolevulinic acid-d2 hydrochloride
5-Aminolevulinic acid-d₂ (hydrochloride) is deuterium labeled 5-Aminolevulinic acid (hydrochloride).

HY-N0305S3

5-Aminolevulinic acid-13C-1 hydrochloride
5-Aminolevulinic acid- ¹³C-1 (5-ALA- ¹³C-1) hydrochloride is the ¹³C labeled 5-Aminolevulinic acid hydrochloride . 5-Aminolevulinic acid hydrochloride (5-ALA hydrochloride) is an intermediate in heme biosynthesis in the body and the universal precursor of tetrapyrroles .

HY-W000450S

5-Aminolevulinic acid-13C
5-Aminolevulinic acid- ¹³C is the ¹³C-labeled 5-Aminolevulinic acid. 5-Aminolevulinic acid (5-ALA) is a non-protein amino acid that plays a rate-limiting role in heme biosynthesis.

HY-W185208S

Chloridazon metabolite B1-d3
Chloridazon metabolite B1-d₃ (Methyldesphenylchloridazon-d₃) is deuterium labeled 5-Amino-4-chloro-2-methyl-2,3-dihydropyridazin-3-one .

HY-W654191

Fipronil detrifluoromethylsulfinyl-13C2,15N2
Fipronil detrifluoromethylsulfinyl- ¹³C2, ¹⁵N₂ is ¹³C and ¹⁵N labeled 5-Amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-1H-pyrazole-3-carbonitrile .

HY-W005394S

*(±)-1-Amino-2-phenylpropane-1,1,3,3,3-d5 hydrochloride*
(±)-1-Amino-2-phenylpropane-1,1,3,3,3-d₅ (hydrochloride) is the deuterium labeled 2-Phenylpropan-1-amine hydrochloride .

HY-W103488S

Chloridazon-d5
Chloridazon-d₅ is the deuterium labeled Chloridazon .

HY-W738480

L-Phenylalanine tert-butyl ester-d5
L-Phenylalanine tert-butyl ester-d₅ ((R)-Tert-Butyl 2-amino-3-phenylpropanoate-d₅) is the deuterium labeled (S)-tert-Butyl 2-amino-3-phenylpropanoate (HY-W108426).

HY-N0305S2

5-Aminolevulinic acid-13C hydrochloride
5-Aminolevulinic acid- ¹³C (hydrochloride) is the ¹³C labeled 5-Aminolevulinic acid hydrochloride . 5-Aminolevulinic acid hydrochloride (5-ALA hydrochloride) is an intermediate in heme biosynthesis in the body and the universal precursor of tetrapyrroles .

HY-77785S

*2-Amino-5-Chlorobenzophenone-d5*
2-Amino-5-Chlorobenzophenone-d₅ is the deuterium labeled 2-Amino-5-Chlorobenzophenone .

HY-B2120S

*2-Amino-5-nitrobenzophenone-d5*
2-Amino-5-nitrobenzophenone-d₅ is the deuterium labeled 2-Amino-5-nitrobenzophenone .

Cat. No.	Product Name		Classification

HY-140810

3-(Azido-PEG5-amino)propanol		Azide
3-(Azido-PEG5-amino)propanol is a PEG linker which contains an azide moiety and a hydroxyl group. 3-(Azido-PEG5-amino)propanol is a click chemistry reagent. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups.

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