2. Apoptosis
  3. TNF Receptor
  4. C5 Lenalidomide

C5 Lenalidomide  (Synonyms: Lenalidomide 5'-amine)

Cat. No.: HY-132248
Handling Instructions

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C5 Lenalidomide (Lenalidomide 5'-amine) is a thalidomide analog and is a potent inhibitor of TNF-alpha production (IC50=100 μM in LPS stimulated human PBMC).

For research use only. We do not sell to patients.

C5 Lenalidomide Chemical Structure

C5 Lenalidomide Chemical Structure

CAS No. : 191732-70-4

Size Price Stock Quantity
Solid + Solvent
10 mM * 1 mL in DMSO
ready for reconstitution
 USD 77 In-stock
Solution
10 mM * 1 mL in DMSO USD 77 In-stock
Solid
50 mg USD 70 In-stock
100 mg USD 110 In-stock
200 mg   Get quote  
500 mg   Get quote  

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This product is a controlled substance and not for sale in your territory.

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Based on 1 publication(s) in Google Scholar

C5 Lenalidomide Related Antibodies

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  • Purity & Documentation

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Description

C5 Lenalidomide (Lenalidomide 5'-amine) is a thalidomide analog and is a potent inhibitor of TNF-alpha production (IC50=100 μM in LPS stimulated human PBMC)[1].

Molecular Weight

259.26

Formula

C13H13N3O3
CAS No.
Appearance

Solid

Color

Off-white to gray

SMILES

O=C(C(N(CC1=C2C=CC(N)=C1)C2=O)CC3)NC3=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (192.86 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.8571 mL 19.2857 mL 38.5713 mL
5 mM 0.7714 mL 3.8571 mL 7.7143 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.8571 mL 19.2857 mL 38.5713 mL 96.4283 mL
5 mM 0.7714 mL 3.8571 mL 7.7143 mL 19.2857 mL
10 mM 0.3857 mL 1.9286 mL 3.8571 mL 9.6428 mL
15 mM 0.2571 mL 1.2857 mL 2.5714 mL 6.4286 mL
20 mM 0.1929 mL 0.9643 mL 1.9286 mL 4.8214 mL
25 mM 0.1543 mL 0.7714 mL 1.5429 mL 3.8571 mL
30 mM 0.1286 mL 0.6429 mL 1.2857 mL 3.2143 mL
40 mM 0.0964 mL 0.4821 mL 0.9643 mL 2.4107 mL
50 mM 0.0771 mL 0.3857 mL 0.7714 mL 1.9286 mL
60 mM 0.0643 mL 0.3214 mL 0.6429 mL 1.6071 mL
80 mM 0.0482 mL 0.2411 mL 0.4821 mL 1.2054 mL
100 mM 0.0386 mL 0.1929 mL 0.3857 mL 0.9643 mL
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C5 Lenalidomide Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

C5 Lenalidomide191732-70-4Lenalidomide 5'-amineTNF ReceptorTumor Necrosis Factor ReceptorTNFRthalidomide analogINHIBITORSTNF PRODUCTIONInhibitorinhibitorinhibit

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