5-Amino-2-methoxyphenol
Based on 1 Customer Validation
5-Amino-2-methoxyphenol is a phenolic regioisomer. 5-Amino-2-methoxyphenol produces dose-dependent antinociception in the mouse formalin test, with its second-phase effect being mechanistically dependent on both FAAH and TRPV1. 5-Amino-2-methoxyphenol can be used for antinociception research.
For research use only. We do not sell to patients.
- CAS No.: 1687-53-2
- Formula: C7H9NO2
- Molecular Weight:139.15
-
Storage:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- Purity & Documentation
- References
-
Help & FAQs
Biological Activity
5-Amino-2-methoxyphenol (compound 2) is conjugated by FAAH in greater amounts, albeit less efficiently and in lesser amounts than 4-Aminopyridine (HY-B0604) in brain homogenate from FAAH+/+ mice[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
5-Amino-2-methoxyphenol (300 mg/kg, i.p., single dose) results in no significant liver injury, as indicated by serum levels of ALT and the ALT/AST ratio[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
-
Animal Model:Male C57BL/6 mice (8 weeks old)[1]
-
Dosage:25, 50, 75 and 100 mg/kg
-
Administration:i.p., single dose
-
Result:Produces dose-dependent antinociception in both phases of the formalin test.
Its antinociceptive effect was inhibited by FAAH inhibitor URB937 (HY-116477) and TRPV1 antagonist Capsazepine (HY-15640) during the second, but not the first , phase of the formalin test at 50 mg/kg dose.
Did not affect locomotor activity in mice at 75 mg/kg.
Chemical Information
-
CAS No. 1687-53-2
-
Appearance Solid
-
Molecular Weight 139.15
-
Formula C7H9NO2
-
SMILES
OC1=CC(N)=CC=C1OC
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Purity & Documentation
-
Data Sheet (270 KB)
-
SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
-
Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
5-Amino-2-methoxyphenol Related Classifications
HY-W025736 Related Classifications
Powered by Bioz