5-Amino-3H-imidazole-4-Carboxamide
Based on 1 publication(s) in Google Scholar
5-Amino-3H-imidazole-4-Carboxamide (5-Aminoimidazole-4-carboxamide; AICA) is an important precursor for the synthesis of purines in general and of the nucleobases adenine and guanine in particular.
For research use only. We do not sell to patients.
- Purity: 99.99%
- CAS No.: 360-97-4
- Formula: C4H6N4O
- Molecular Weight:126.12
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Storage:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Publications Citing Use of MedChemExpress (MCE) 5-Amino-3H-imidazole-4-Carboxamide
MoreAll Endogenous Metabolite Isoforms
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Biological Activity
Chemical Information
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CAS No. 360-97-4
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Appearance Solid
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Molecular Weight 126.12
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Formula C4H6N4O
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Color Off-white to light brown
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SMILES
O=C(C1=C(N)NC=N1)N
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Synonyms
5-Aminoimidazole-4-carboxamide; AICA
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Publications (1)
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Journal Impact Factor
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Most Recent
Solvent & Solubility
DMSO : 100 mg/mL (792.90 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
H2O : 20 mg/mL (158.58 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
For the following dissolution methods, please prepare the working solution directly:
It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Add each solvent one by one: PBS
Solubility: 15 mg/mL (118.93 mM); Clear solution; Need ultrasonic
Purity & Documentation
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Data Sheet (277 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O / DMSO | 1 mM | 7.9290 mL | 39.6448 mL | 79.2896 mL | 198.2239 mL |
| 5 mM | 1.5858 mL | 7.9290 mL | 15.8579 mL | 39.6448 mL | |
| 10 mM | 0.7929 mL | 3.9645 mL | 7.9290 mL | 19.8224 mL | |
| 15 mM | 0.5286 mL | 2.6430 mL | 5.2860 mL | 13.2149 mL | |
| 20 mM | 0.3964 mL | 1.9822 mL | 3.9645 mL | 9.9112 mL | |
| 25 mM | 0.3172 mL | 1.5858 mL | 3.1716 mL | 7.9290 mL | |
| 30 mM | 0.2643 mL | 1.3215 mL | 2.6430 mL | 6.6075 mL | |
| 40 mM | 0.1982 mL | 0.9911 mL | 1.9822 mL | 4.9556 mL | |
| 50 mM | 0.1586 mL | 0.7929 mL | 1.5858 mL | 3.9645 mL | |
| 60 mM | 0.1321 mL | 0.6607 mL | 1.3215 mL | 3.3037 mL | |
| 80 mM | 0.0991 mL | 0.4956 mL | 0.9911 mL | 2.4778 mL | |
| 100 mM | 0.0793 mL | 0.3964 mL | 0.7929 mL | 1.9822 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.