2. GPCR/G Protein Neuronal Signaling Metabolic Enzyme/Protease
  3. mGluR Endogenous Metabolite
  4. O-Phospho-L-serine-13C3,15N

O-Phospho-L-serine-13C3,15N  (Synonyms: L-Serine O-phosphate-13C3,15N; L-SOP-13C3,15N)

Cat. No.: HY-15129S
COA
SDS
Instrucciones de manejo Technical Support

O-Phospho-L-serine-13C3,15N is the 13C- and 15N-labeled O-Phospho-L-serine. O-Phospho-L-serine is the immediate precursor to L-serine in the serine synthesis pathway, and an agonist at the group III mGluR receptors (mGluR4, mGluR6, mGluR7, and mGluR8); O-Phospho-L-serine also acts as a weak antagonist for mGluR1 and a potent antagonist for mGluR2.

Para uso exclusivo en investigación. No vendemos a pacientes.

O-Phospho-L-serine-<sup>13</sup>C<sub>3</sub>,<sup>15</sup>N

O-Phospho-L-serine-13C3,15N Estructura química

No. CAS : 2734706-69-3

Tamaño Precio Stock Cantidad
500 μg Obtener un presupuesto
1 mg Obtener un presupuesto
5 mg Obtener un presupuesto
10 mg   Obtener un presupuesto  
50 mg   Obtener un presupuesto  

* Seleccione Cantidad antes de agregar artículos.

This product is a controlled substance and not for sale in your territory.

Revisión del cliente

Based on 1 Customer Validation

Other Forms of O-Phospho-L-serine-13C3,15N:

O-Phospho-L-serine-13C3,15N Related Antibodies

Top Publications Citing Use of Products

Ver todos los productos específicos de isoformas mGluR:

Ver todas las isoformas
mGluR1 mGluR2 mGluR3 mGluR4 mGluR5 mGluR6 mGluR7 mGluR8 mGluR

Ver todos los productos específicos de isoformas Endogenous Metabolite:

Ver todas las isoformas
Human Endogenous Metabolite Microbial Metabolite

  • Actividad biológica

  • Pureza y Documentación

  • Referencias

  • Revisión del cliente

Descripciòn

O-Phospho-L-serine-13C3,15N is the 13C- and 15N-labeled O-Phospho-L-serine. O-Phospho-L-serine is the immediate precursor to L-serine in the serine synthesis pathway, and an agonist at the group III mGluR receptors (mGluR4, mGluR6, mGluR7, and mGluR8); O-Phospho-L-serine also acts as a weak antagonist for mGluR1 and a potent antagonist for mGluR2[1].

Application

1. This compound can be used as a tracer.
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

O-Phospho-L-serine-13C3,15N Related Antibodies
Peso molecular

189.04

Fòrmula

13C3H8 15NO6P
No. CAS
Unlabeled CAS
Appearance

Solid

Color

Off-white to light yellow

SMILES

OP(O[13CH2][13C@H]([15NH2])[13C](O)=O)(O)=O
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvente y solubilidad
In Vitro: 

H2O : 25 mg/mL (132.25 mM; Need ultrasonic and warming)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 5.2899 mL 26.4494 mL 52.8989 mL
5 mM 1.0580 mL 5.2899 mL 10.5798 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Calculadora de molaridad

  • Calculadora de dilución

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Pureza y Documentación

Purity: 99.19%

SDS (416 KB)

COA (250 KB) Elemental Analysis Report (109 KB)

Instrucciones de manejo (2659 KB)
Referencias

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 5.2899 mL 26.4494 mL 52.8989 mL 132.2471 mL
5 mM 1.0580 mL 5.2899 mL 10.5798 mL 26.4494 mL
10 mM 0.5290 mL 2.6449 mL 5.2899 mL 13.2247 mL
15 mM 0.3527 mL 1.7633 mL 3.5266 mL 8.8165 mL
20 mM 0.2645 mL 1.3225 mL 2.6449 mL 6.6124 mL
25 mM 0.2116 mL 1.0580 mL 2.1160 mL 5.2899 mL
30 mM 0.1763 mL 0.8816 mL 1.7633 mL 4.4082 mL
40 mM 0.1322 mL 0.6612 mL 1.3225 mL 3.3062 mL
50 mM 0.1058 mL 0.5290 mL 1.0580 mL 2.6449 mL
60 mM 0.0882 mL 0.4408 mL 0.8816 mL 2.2041 mL
80 mM 0.0661 mL 0.3306 mL 0.6612 mL 1.6531 mL
100 mM 0.0529 mL 0.2645 mL 0.5290 mL 1.3225 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.

O-Phospho-L-serine-13C3,15N Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

O-Phospho-L-serine-13C3,15N2734706-69-3L-Serine O-phosphate-13C3,15NL-SOP-13C3,15NmGluREndogenous MetaboliteMetabotropic glutamate receptorsInhibitorinhibitorinhibit

Productos vistos recientemente:

Consulta en línea

Your information is safe with us. * Required Fields.

Nombre del producto

  

Requested Quantity *

Nombre del solicitante *

 

Saludo

Direcciòn del E-mail *

 

Número de teléfono *

Department

 

Nombre de la Organizaciòn *

City

Provincia

Country or Region *

      

Observaciones

Consulta para venta a granel

Inquiry Information

Nombre del producto:
O-Phospho-L-serine-13C3,15N
Cat. No.:
HY-15129S
Cantidad:
MCE Japan Authorized Agent:

Revisión del cliente

Thank You for Your Feedback!

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

Nombre del producto

  

Lot #

Nombre del solicitante *

 

Direcciòn del E-mail *

Número de teléfono

 

Department *

Nombre de la Organizaciòn *

 

Country or Region *

Observaciones

SAFETY DATA SHEET (SDS)

English - EN (416 KB) Français - FR (416 KB) Deutsch - DE (416 KB) Norwegian - NO (416 KB) Español - ES (416 KB) Swedish - SV (416 KB) Italian - IT (416 KB) Korean - KR (416 KB) Portuguese - PT (416 KB)

Request for HNMR Report

We have received your request and will respond to you as soon as possible.