Search Result

Results for "

β-adrenergic receptor agonist

" in MedChemExpress (MCE) Product Catalog:

By Targets:	5-HT Receptor (1) Adrenergic Receptor (40) Biochemical Assay Reagents (1) Calcium Channel (1) Drug Derivative (1) Endogenous Metabolite (6) GABA Receptor (1) GPR109A (1) iGluR (6) Influenza Virus (2) Isotope-Labeled Compounds (12) LXR (2) Potassium Channel (1) Reference Standards (6) Serpin (1) Trace Amine-associated Receptor (TAAR) (6) TRP Channel (1)
By Research Areas:	Cancer (2) Cardiovascular Disease (19) Endocrinology (15) Infection (4) Inflammation/Immunology (14) Metabolic Disease (18) Neurological Disease (10)

Inhibitors & Agonists

Peptides

Natural
Products

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-B0468

Isoprenaline hydrochloride Maximum Cited Publications 87 Publications Verification Isoproterenol hydrochloride	Adrenergic Receptor Endogenous Metabolite	Cardiovascular Disease Endocrinology
Isoprenaline (Isoproterenol) hydrochloride is a non-selective, orally active **β-adrenergic receptor** agonist. Isoprenaline has potent peripheral vasodilator, bronchodilator, and cardiac stimulating activities. Isoprenaline can be used for the research of bradycardia and bronchial asthma .

HY-108353

Isoprenaline Maximum Cited Publications 87 Publications Verification	Adrenergic Receptor Endogenous Metabolite	Cardiovascular Disease Endocrinology
Isoprenaline is a non-selective, orally active **β-adrenergic receptor** agonist. Isoprenaline has potent peripheral vasodilator, bronchodilator, and cardiac stimulating activities. Isoprenaline can be used for the research of bradycardia and bronchial asthma .

HY-B1270

Isoxsuprine hydrochloride	Adrenergic Receptor iGluR	Neurological Disease Endocrinology
Isoxsuprine hydrochloride is a **beta-adrenergic receptor** agonist with K_is of 13.65 μΜ and 3.48 μΜ for myometrial and placcntal beta-adrenergic receptor, respectively. Isoxsuprine hydrochloride is also a NMDA receptor antagonist.

HY-18282

AZ876	LXR	Cardiovascular Disease Metabolic Disease Cancer
AZ876 is a selective, orally active agonist of liver X receptor (LXRα/β) (K_i=0.007 μM [LXRα, human], 0.011 μM [LXRβ, human]. AZ876 induces the expression of target genes such as ABCA1 and ABCG1, promotes reverse cholesterol transport (RCT) and regulates lipid metabolism and anti-inflammatory effects. AZ876 increases cardiac polyunsaturated fatty acid levels, reduces myocardial fibrosis, and reduces lesion area and monocyte adhesion in atherosclerosis models. AZ876 can be used in cardiovascular disease research, such as preventing and treating *β-adrenergic*-induced cardiac diastolic dysfunction and inhibiting the progression of atherosclerosis .

HY-100634

4-Hydroxypropranolol hydrochloride (±)-4-hydroxy Propranolol hydrochloride	Adrenergic Receptor	Cardiovascular Disease
4-Hydroxypropranolol hydrochloride is a non-cardiac selective **β-adrenergic receptor** antagonist and a metabolite produced after oral administration of Propranolol (HY-B0573B). 4-Hydroxypropranolol hydrochloride also acts as a membrane stabilizer and possesses intrinsic sympathomimetic inhibitory activity. 4-Hydroxypropranolol hydrochloride blocks β-adrenergic receptors to antagonize the effects of catecholamines, acts as a partial β-adrenergic receptor agonist, and induces membrane stabilization. 4-Hydroxypropranolol hydrochloride alters heart rate, left ventricular contractility, and atrioventricular conduction time. 4-Hydroxypropranolol hydrochloride can be used in research related to cardiovascular and cerebrovascular diseases .

HY-107580

GPR109 receptor agonist-1	GPR109A	Cardiovascular Disease Metabolic Disease Inflammation/Immunology
GPR109 receptor agonist-1 is a highly selective agonist of the human orphan G protein-coupled receptor GPR109b, and does not activate the mouse homologous receptor PUMA-G. GPR109 receptor agonist-1 functionally modulates the human GPR109b receptor via the cAMP signaling pathway, with an EC₅₀ of 400 nM. GPR109 receptor agonist-1 inhibits isoproterenol (HY-B0468)-stimulated lipolysis in human subcutaneous adipocytes, with efficacy comparable to that of Niacin (HY-B0143), and does not act on β-adrenergic receptors. GPR109 receptor agonist-1 can be used in studies related to dyslipidemia and atherosclerosis .

HY-B1421

Ractopamine hydrochloride LY031537	Adrenergic Receptor Trace Amine-associated Receptor (TAAR)	Metabolic Disease
Ractopamine hydrochloride (LY031537) is a potent and orally active **β-adrenergic receptor (βAR*) agonist* with K_d value of ~25 nM for pig β1AR and β2AR. Ractopamine hydrochloride also is a mTAAR1 agonist with an EC₅₀ of 16 μM. Ractopamine hydrochloride promotes muscle mass development, limits fat deposition, reduces feed consumption, increases total cellular protein synthesis, and improves growth rate and feed efficiency in finishing swine. Ractopamine hydrochloride can be used for researching to increase lean tissue growth and improve production efficiency in pigs .

HY-100935

Cimaterol CL 263780; (±)-2-Amino-5-[1-hydroxy-2-[(1-methylethyl)amino]ethyl]benzonitrile	Adrenergic Receptor	Metabolic Disease
Cimaterol (CL 263780) is a *β-adrenergic* agonist on energy metabolism in ob/ob mice . The K_d for Cimaterol binding to the L6 β-receptor is 26 nM which is compatible with its EC₅₀ for the stimulation of protein synthesis (approx 5 nM) .

HY-B1404

Nylidrin hydrochloride Buphenine hydrochloride	iGluR Influenza Virus	Infection Cardiovascular Disease Inflammation/Immunology
Nylidrin hydrochloride (Buphenine hydrochloride) is an orally active *β-adrenergic* agonist. Nylidrin hydrochloride antagonizes NR1_A/2B NMDA receptors (IC₅₀ = 0.18 μM in Xenopus oocytes). Nylidrin hydrochloride reduces the levels of NP, HA, and M1. Nylidrin hydrochloride has antiviral activity against multiple H1N1 subtype influenza A viruses. Nylidrin hydrochloride improves hemorrhagic shock and anti-allergic effects .

HY-B1481

Isoetharine mesylate Isoetarine mesylate	Adrenergic Receptor	Cardiovascular Disease Inflammation/Immunology
Isoetharine (Isoetarine) mesylate is an orally active selective agonist of **β-adrenergic receptors**. Isoetharine mesylate is a catechol-like agent and catechol O-methyltransferase (COMT) mediates its methylation. Isoetharine mesylate can promote the production of cAMP which stimulates the relaxation of smooth muscle cells and can be used as an emphysema, bronchitis and bronchodilator .

HY-B1694A

Methoxyphenamine hydrochloride NSC-65644	Adrenergic Receptor	Inflammation/Immunology Endocrinology
Methoxyphenamine hydrochloride, a non-regulated analog of Methamphetamine, is a **β-adrenergic receptor** agonist used as a bronchodilator .

HY-P10336

Serpinin	Serpin	Neurological Disease Endocrinology
Serpinin is an agonist of the protease inhibitor Nexin-1 (PN-1). Serpinin upregulates the expression of PN-1 through the cAMP-PKA-Sp1 signaling pathway, promoting granule biogenesis in endocrine cells. Serpinin is used in research related to the regulation of secretory function . Serpinin is a selective agonist for **β-adrenergic receptors*. Serpinin interacts with β1-adrenergic* receptors to activate the AC-cAMP-PKA pathway, which regulates myocardial systolic and diastolic function. pGlu-serpinin upregulates Bcl2 mRNA transcription and exerts neuroprotective effects .

HY-108353A

Isoprenaline hemisulfate Maximum Cited Publications 87 Publications Verification	Adrenergic Receptor Endogenous Metabolite	Cardiovascular Disease Endocrinology
Isoprenaline hemisulfate is a non-selective, orally active **β-adrenergic receptor** agonist. Isoprenaline has potent peripheral vasodilator, bronchodilator, and cardiac stimulating activities. Isoprenaline can be used for the research of bradycardia and bronchial asthma .

HY-101393A

CGP 12177 hydrochloride (±)-CGP 12177 hydrochloride	Adrenergic Receptor	Cardiovascular Disease Metabolic Disease
CGP 12177 ((±)-CGP 12177) hydrochloride is a β-Adrenergic receptor (β-AR) ligand. CGP 12177 hydrochloride is a β₃-AR (K_i = 88 nM) agonist with β₁/β₂-AR (K_i = 0.9 nM for β₁; K_i = 4 nM for β₂) antagonist action. CGP 12177 hydrochloride exhibits partial agonist properties for α₁-AR in rat pulmonary artery. CGP 12177 hydrochloride regulates the expression of ucp and leptin genes in NMRI mice adipose tissues. CGP 12177 hydrochloride can be used for cardiovascular and metabolic disease research ^[1][2][3][4].

HY-B1481A

Isoetharine Isoetarine	Adrenergic Receptor	Cardiovascular Disease Inflammation/Immunology
Isoetharine (Isoetarine) is an orally active selective agonist of **β-adrenergic receptors**. Isoetharine is a catechol-like agent and catechol O-methyltransferase (COMT) mediates its methylation. Isoetharine can promote the production of cAMP which stimulates the relaxation of smooth muscle cells and can be used as an emphysema, bronchitis and bronchodilator .

HY-131145

Brombuterol hydrochloride Bromobuterol hydrochloride	Adrenergic Receptor	Inflammation/Immunology
Brombuterol hydrochloride (Bromobuterol hydrochloride) is a **β-adrenergic receptor** agonist .

HY-121185

Hexoprenaline	Adrenergic Receptor	Infection Neurological Disease Inflammation/Immunology Endocrinology
Hexoprenaline is an orally active and selective **β-adrenergic receptor** agonist. Hexoprenaline can dilate the bronchi. Hexoprenaline can activate adenylate cyclase and increases 14C-Aminopyrine uptake. Hexoprenaline exhibits anti-infection and anti-inflammmation effect. Hexoprenaline can increase placental weight and blood flow. Hexoprenaline can be used for the researches of inflammation, immunology, infection, endocrinology and neurological disease, such as asthma, chronic bronchitis, sepsis and intoxication of organophosphorus compounds .

HY-B1694

Methoxyphenamine NSC-65644 free base	Adrenergic Receptor	Inflammation/Immunology Endocrinology
Methoxyphenamine is a β-adrenergic receptor agonist of the amphetamine class used as a bronchodilator.

HY-131104AS

Brombuterol-d9 hydrochloride Bromobuterol D9 hydrochloride	Isotope-Labeled Compounds Adrenergic Receptor	Inflammation/Immunology
Brombuterol-d₉ (hydrochloride) is a deuterium labeled Brombuterol hydrochloride. Brombuterol hydrochloride is a β-adrenergic receptor agonist .

HY-120519

L-665871	Adrenergic Receptor	Metabolic Disease
L-665871 is a orally active **β-adrenergic receptor** agonist that can be used as a swine growth promoter .

HY-B0468R

Isoprenaline hydrochloride (Standard) Isoproterenol hydrochloride (Standard)	Reference Standards Adrenergic Receptor Endogenous Metabolite	Cardiovascular Disease Endocrinology
Isoprenaline (hydrochloride) (Standard) is the analytical standard of Isoprenaline (hydrochloride). This product is intended for research and analytical applications. Isoprenaline (Isoproterenol) hydrochloride is a non-selective, orally active β-adrenergic receptor agonist. Isoprenaline has potent peripheral vasodilator, bronchodilator, and cardiac stimulating activities. Isoprenaline can be used for the research of bradycardia and bronchial asthma .

HY-114630

Protokylol Caytine; JB-251	TRP Channel Adrenergic Receptor	Cardiovascular Disease
Protokylol (Caytine; JB-251) is a beta-adrenergic receptor agonist and TRPV1 agonist. Protokylol is used as a bronchodilator .

HY-B1421S

Ractopamine-d6 hydrochloride LY031537-d₆	Isotope-Labeled Compounds Adrenergic Receptor	Metabolic Disease
Ractopamine-d₆ (LY031537-d₆) hydrochloride is the deuterium labeled Ractopamine hydrochloride (HY-B1421). Ractopamine (LY031537) hydrochloride is a potent β-adrenergic receptor (βAR) agonist with K_d values of ~25 nM for pig β₁AR and β₂AR. Ractopamine hydrochloride is linked to protein metabolism. Ractopamine hydrochloride can be used for researching to increase lean tissue growth and improve production efficiency in pigs .

HY-101393

CGP 12177 (±)-CGP 12177	Adrenergic Receptor	Cardiovascular Disease Metabolic Disease
CGP 12177 ((±)-CGP 12177) is a β-Adrenergic receptor (β-AR) ligand. CGP 12177 is a β₃-AR (K_i = 88 nM) agonist with β₁/β₂-AR (K_i = 0.9 nM for β₁; K_i = 4 nM for β₂) antagonist action. CGP 12177 exhibits partial agonist properties for α₁-AR in rat pulmonary artery. CGP 12177 regulates the expression of ucp and leptin genes in NMRI mice adipose tissues. CGP 12177 can be used for cardiovascular and metabolic disease research .

HY-18282R

AZ876 (Standard)	LXR	Cardiovascular Disease Metabolic Disease Cancer
AZ876 (Standard) is the analytical standard of AZ876. This product is intended for research and analytical applications. AZ876 is a selective, orally active agonist of liver X receptor (LXRα/β) (Ki=0.007 μM [LXRα, human], 0.011 μM [LXRβ, human]. AZ876 induces the expression of target genes such as ABCA1 and ABCG1, promotes reverse cholesterol transport (RCT) and regulates lipid metabolism and anti-inflammatory effects. AZ876 increases cardiac polyunsaturated fatty acid levels, reduces myocardial fibrosis, and reduces lesion area and monocyte adhesion in atherosclerosis models. AZ876 can be used in cardiovascular disease research, such as preventing and treating β-adrenergic-induced cardiac diastolic dysfunction and inhibiting the progression of atherosclerosis .

HY-131104S

Brombuterol-d9 Bromobuterol-d₉	Isotope-Labeled Compounds Adrenergic Receptor	Inflammation/Immunology
Brombuterol-d₉ is a deuterium labeled Brombuterol. Brombuterol is a β-adrenergic receptor agonist .

HY-113320R

Etiocholanolone (Standard) 5β-Androsterone (Standard)	Reference Standards GABA Receptor Endogenous Metabolite	Neurological Disease
Cimbuterol (Standard) is the analytical standard of Cimbuterol. This product is intended for research and analytical applications. Cimbuterol is a β-adrenergic receptor agonist .

HY-131145R

Brombuterol hydrochloride (Standard) Bromobuterol hydrochloride (Standard)	Reference Standards Adrenergic Receptor	Inflammation/Immunology
Brombuterol (hydrochloride) (Standard) is the analytical standard of Brombuterol (hydrochloride). This product is intended for research and analytical applications. Brombuterol hydrochloride (Bromobuterol hydrochloride) is a β-adrenergic receptor agonist .

HY-178319

Photoazolol-1 PZL-1	Drug Derivative Adrenergic Receptor	Cardiovascular Disease
Photoazolol-1 is a **β-adrenergic receptor (βAR*)-blocker derivative. Photoazolol-1 can transfer from an inverse agonist* to a neutral antagonist upon photoactivation .

HY-B0468S

Isoprenaline-d7 hydrochloride Isoproterenol-d7 hydrochloride	Isotope-Labeled Compounds Endogenous Metabolite Adrenergic Receptor	Cardiovascular Disease
Isoprenaline-d7 (hydrochloride) is a deuterated labeled Isoprenaline (hydrochloride) . Isoprenaline (Isoproterenol) hydrochloride is a non-selective, orally active **β-adrenergic receptor** agonist. Isoprenaline has potent peripheral vasodilator, bronchodilator, and cardiac stimulating activities. Isoprenaline can be used for the research of bradycardia and bronchial asthma .

HY-100935R

Cimaterol (Standard) CL 263780 (Standard); (±)-2-Amino-5-[1-hydroxy-2-[(1-methylethyl)amino]ethyl]benzonitrile (Standard)	Reference Standards Adrenergic Receptor	Metabolic Disease
Cimaterol (Standard) is the analytical standard of Cimaterol. This product is intended for research and analytical applications. Cimaterol (CL 263780) is a β-adrenergic agonist on energy metabolism in ob/ob mice . The Kd for Cimaterol binding to the L6 β-receptor is 26 nM which is compatible with its EC50 for the stimulation of protein synthesis (approx 5 nM) .

HY-128515

Metaterol	Adrenergic Receptor	Endocrinology
Metaterol is a **beta-adrenergic receptor** agonist .

HY-B1270A

Isoxsuprine	Adrenergic Receptor iGluR	Neurological Disease Endocrinology
Isoxsuprine is a **beta-adrenergic receptor** agonist with K_is of 13.65 μΜ and 3.48 μΜ for myometrial and placcntal beta-adrenergic receptor, respectively. Isoxsuprine hydrochloride is also a NMDA receptor antagonist.

HY-B1270S

Isoxsuprine-d6 hydrochloride	Isotope-Labeled Compounds Adrenergic Receptor iGluR	Neurological Disease Endocrinology
Isoxsuprine-d₆ (hydrochloride) is the deuterium labeled Isoxsuprine hydrochloride. Isoxsuprine hydrochloride is a beta-adrenergic receptor agonist with Kis of 13.65 μΜ and 3.48 μΜ for myometrial and placcntal beta-adrenergic receptor, respectively. Isoxsuprine hydrochloride is also a NMDA receptor antagonist.

HY-100935S

Cimaterol-d7 CL 263780-d₇	Isotope-Labeled Compounds Adrenergic Receptor	Endocrinology
Cimaterol-d₇ is the deuterium labeled Cimaterol. Cimaterol is a potent agonist of β-adrenergic receptors (pEC50s=8.13, 8.78, and 6.62 for human β1, β2, and β3, respectively). Cimaterol has been used in farmed animals to increase carcass mass and to alter muscle and fat deposition.

HY-B1270R

Isoxsuprine hydrochloride (Standard)	Reference Standards Adrenergic Receptor iGluR	Neurological Disease Endocrinology
Isoxsuprine hydrochloride (Standard) is the analytical standard of Isoxsuprine hydrochloride. This product is intended for research and analytical applications. Isoxsuprine hydrochloride is a beta-adrenergic receptor agonist with Kis of 13.65 μΜ and 3.48 μΜ for myometrial and placcntal beta-adrenergic receptor, respectively. Isoxsuprine hydrochloride is also a NMDA receptor antagonist.

HY-113781

Ractopamine LY031537 free base	Adrenergic Receptor Trace Amine-associated Receptor (TAAR)	Metabolic Disease
Ractopamine (LY031537 free base) is a potent and orally active **β-adrenergic receptor (βAR*) agonist* with K_d value of ~25 nM for pig β1AR and β2AR. Ractopamine also is a mTAAR1 agonist with an EC₅₀ of 16 μM. Ractopamine promotes muscle mass development, limits fat deposition, reduces feed consumption, increases total cellular protein synthesis, and improves growth rate and feed efficiency in finishing swine. Ractopamine can be used for researching to increase lean tissue growth and improve production efficiency in pigs .

HY-121185A

Hexoprenaline sulfate	Adrenergic Receptor	Infection Neurological Disease Inflammation/Immunology Endocrinology
Hexoprenaline sulfate is an orally active and selective **β-adrenergic receptor** agonist. Hexoprenaline sulfate can dilate the bronchi. Hexoprenaline sulfate can activate adenylate cyclase and increases 14C-Aminopyrine uptake. Hexoprenaline sulfate exhibits anti-infection and anti-inflammmation effect. Hexoprenaline sulfate can increase placental weight and blood flow. Hexoprenaline sulfate can be used for the researches of inflammation, immunology, infection, endocrinology and neurological disease, such as asthma, chronic bronchitis, sepsis and intoxication of organophosphorus compounds .

HY-B1404R

Nylidrin hydrochloride (Standard) Buphenine hydrochloride (Standard)	Reference Standards iGluR Influenza Virus	Infection Cardiovascular Disease Inflammation/Immunology
Nylidrin (hydrochloride) (Standard) is the analytical standard of Nylidrin hydrochloride (HY-B1404). This product is intended for research and analytical applications. Nylidrin hydrochloride (Buphenine hydrochloride) is an orally active *β-adrenergic* agonist. Nylidrin hydrochloride antagonizes NR1_A/2B NMDA receptors (IC₅₀ = 0.18 μM in Xenopus oocytes). Nylidrin hydrochloride reduces the levels of NP, HA, and M1. Nylidrin hydrochloride has antiviral activity against multiple H1N1 subtype influenza A viruses. Nylidrin hydrochloride improves hemorrhagic shock and anti-allergic effects .

HY-W751276

Ractopamine-13C6	Isotope-Labeled Compounds Adrenergic Receptor Trace Amine-associated Receptor (TAAR)	Metabolic Disease
Ractopamine- ¹³C₆ is the ¹³C-labeled Ractopamine (HY-113781). Ractopamine (LY031537 free base) is a potent and orally active **β-adrenergic receptor (βAR*) agonist* with K_d value of ~25 nM for pig β1AR and β2AR. Ractopamine also is a mTAAR1 agonist with an EC₅₀ of 16 μM. Ractopamine promotes muscle mass development, limits fat deposition, reduces feed consumption, increases total cellular protein synthesis, and improves growth rate and feed efficiency in finishing swine. Ractopamine can be used for researching to increase lean tissue growth and improve production efficiency in pigs .

HY-W751275

Ractopamine-13C2	Isotope-Labeled Compounds Adrenergic Receptor Trace Amine-associated Receptor (TAAR)	Metabolic Disease
Ractopamine- ¹³C₂ is the ¹³C-labeled Ractopamine (HY-113781). Ractopamine (LY031537 free base) is a potent and orally active **β-adrenergic receptor (βAR*) agonist* with K_d value of ~25 nM for pig β1AR and β2AR. Ractopamine also is a mTAAR1 agonist with an EC₅₀ of 16 μM. Ractopamine promotes muscle mass development, limits fat deposition, reduces feed consumption, increases total cellular protein synthesis, and improves growth rate and feed efficiency in finishing swine. Ractopamine can be used for researching to increase lean tissue growth and improve production efficiency in pigs .

HY-103117

S 32212 hydrochloride	5-HT Receptor	Neurological Disease
S 32212 hydrochloride is an inverse agonist of 5-HT receptors 5-HT2(CINI) and 5-HT2(CVSV) (Kis=6.6, 8.9 nM) and an antagonist of 5-HT2A and α2β-adrenergic receptors (Ki=5.8, 5.8 nM). S 32212 hydrochloride can reduce the binding of GTPγS to Gαq, and reduce the activity of phospholipase C (PLC) in HEK293 cells expressing 5-HT2(CINI) receptor and CHO cells expressing 5-HT2(CVSV) receptor (EC₅₀=38 and 18.6 nM, respectively). S 32212 hydrochloride (2.5 mg/kg) reduces 5-HT receptor agonist-induced head twitches and penile erections in mice and rats. S 32212 hydrochloride (10, 40 mg/kg) reduces immobility time in the forced swim test and marble burying behavior in mice and rats, exerting antidepressant and anxiolytic activities.

HY-113781S

Ractopamine-d6 LY031537 free base-d6	Isotope-Labeled Compounds Adrenergic Receptor Trace Amine-associated Receptor (TAAR)	Metabolic Disease
Ractopamine-d₆ is the deuterium labeled Ractopamine (HY-113781). Ractopamine (LY031537) hydrochloride is a potent β-adrenergic receptor (βAR) agonist with K_d values of ~25 nM for pig β₁AR and β₂AR. Ractopamine hydrochloride is linked to protein metabolism. Ractopamine hydrochloride can be used for researching to increase lean tissue growth and improve production efficiency in pigs .

HY-114833

Bunolol (Rac)-Bunolol; dl-Bunolol	Adrenergic Receptor	Cardiovascular Disease Neurological Disease
Bunolol ((Rac)-Bunolol) is a **β-adrenergic receptor** blocker. Bunolol antagonizes the β-receptor agonist activity induced by Isoproterenol (HY-B0468) and Dichloroisoproterenol. Bunolol reduces the heart rate and mean blood pressure of anesthetized dogs. Bunolol decreases spontaneous motor activity and Amphetamine-induced hyperactivity in rats, potentiates Pentobarbital-induced hypnosis in mice, and protects rats from extensor tonic convulsions induced by maximal electroshock .

HY-19002

BRL-26830A	Adrenergic Receptor	Metabolic Disease
BRL-26830A is a **β-adrenergic receptor** agonist. BRL-26830A reduces body weight and increases metabolic rate in obese mouse models. BRL-26830A stimulates insulin release and significantly reduces blood glucose levels in ICR mouse models. BRL-26830A can be used to study endocrine and metabolic diseases such as obesity and diabetes .

HY-B1421S1

Ractopamine-d9 hydrochloride LY031537-d₉	Isotope-Labeled Compounds Adrenergic Receptor	Metabolic Disease
Ractopamine-d₉ (LY031537-d₉) hydrochloride is the deuterium labeled Ractopamine hydrochloride (HY-B1421). Ractopamine (LY031537) hydrochloride is a potent β-adrenergic receptor (βAR) agonist with K_d values of ~25 nM for pig β₁AR and β₂AR. Ractopamine hydrochloride is linked to protein metabolism. Ractopamine hydrochloride can be used for researching to increase lean tissue growth and improve production efficiency in pigs .

HY-B1421S3

Ractopamine-d5 hydrochloride LY031537-d₅	Isotope-Labeled Compounds Adrenergic Receptor	Metabolic Disease
Ractopamine-d₅ (LY031537-d₅) hydrochloride is the deuterium labeled Ractopamine hydrochloride (HY-B1421). Ractopamine (LY031537) hydrochloride is a potent β-adrenergic receptor (βAR) agonist with K_d values of ~25 nM for pig β₁AR and β₂AR. Ractopamine hydrochloride is linked to protein metabolism. Ractopamine hydrochloride can be used for researching to increase lean tissue growth and improve production efficiency in pigs .

HY-E71266

β-Adrenergic-receptor kinase	Biochemical Assay Reagents	Others
β-Adrenergic-receptor kinase (EC 2.7.11.15) requires G-protein for activation and therefore belongs to the family of G-protein-dependent receptor kinases (GRKs) . Acts on the agonist-occupied form of the receptor; also phosphorylates rhodopsin, but more slowly.

HY-B1421S2

Ractopamine-d3 hydrochloride LY031537-d₃	Isotope-Labeled Compounds Adrenergic Receptor Trace Amine-associated Receptor (TAAR)	Metabolic Disease
Ractopamine-d₃ (LY031537-d₃) hydrochloride is the deuterium labeled Ractopamine hydrochloride (HY-B1421). Ractopamine hydrochloride (LY031537) is a potent and orally active **β-adrenergic receptor (βAR*) agonist* with K_d value of ~25 nM for pig β1AR and β2AR. Ractopamine hydrochloride also is a mTAAR1 agonist with an EC₅₀ of 16 μM. Ractopamine hydrochloride promotes muscle mass development, limits fat deposition, reduces feed consumption, increases total cellular protein synthesis, and improves growth rate and feed efficiency in finishing swine. Ractopamine hydrochloride can be used for researching to increase lean tissue growth and improve production efficiency in pigs .

HY-183206

UR 8225	Potassium Channel Calcium Channel	Cardiovascular Disease Inflammation/Immunology
UR 8225 is an orally active ATP-sensitive K ⁺ channel activator with vasodilator, smooth muscle relaxant, antihypertensive, and bronchodilator activities. UR 8225 induces membrane hyperpolarization by increasing outward K ⁺ conductance and reduces Ca ²⁺ influx through voltage-gated L-type Ca ²⁺ channels. UR 8225 reduces total peripheral vascular resistance, shortens cardiac action potential duration, inhibits agonist-induced Ca ²⁺ influx, and stimulates renin release. UR 8225 induces reflex tachycardia but lacks β-adrenergic receptor blocking activity. UR 8225 is widely applicable to research in fields related to hypertension, myocardial ischemia, ventricular fibrillation, and other conditions .

Cat. No.	Product Name	Target	Research Area

HY-P10336

Serpinin	Serpin	Neurological Disease Endocrinology
Serpinin is an agonist of the protease inhibitor Nexin-1 (PN-1). Serpinin upregulates the expression of PN-1 through the cAMP-PKA-Sp1 signaling pathway, promoting granule biogenesis in endocrine cells. Serpinin is used in research related to the regulation of secretory function . Serpinin is a selective agonist for **β-adrenergic receptors*. Serpinin interacts with β1-adrenergic* receptors to activate the AC-cAMP-PKA pathway, which regulates myocardial systolic and diastolic function. pGlu-serpinin upregulates Bcl2 mRNA transcription and exerts neuroprotective effects .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-B0468

Isoprenaline hydrochloride Maximum Cited Publications 87 Publications Verification Isoproterenol hydrochloride	Cardiovascular Disease Alkaloids Classification of Application Fields Other Alkaloids Phenols Polyphenols Endogenous metabolite Disease Research Fields Endocrinology Source Classification	Adrenergic Receptor Endogenous Metabolite
Isoprenaline (Isoproterenol) hydrochloride is a non-selective, orally active **β-adrenergic receptor** agonist. Isoprenaline has potent peripheral vasodilator, bronchodilator, and cardiac stimulating activities. Isoprenaline can be used for the research of bradycardia and bronchial asthma .

HY-108353

Isoprenaline Maximum Cited Publications 87 Publications Verification	Cardiovascular Disease Alkaloids Classification of Application Fields Other Alkaloids Phenols Polyphenols Endogenous metabolite Disease Research Fields Endocrinology Source Classification	Adrenergic Receptor Endogenous Metabolite
Isoprenaline is a non-selective, orally active **β-adrenergic receptor** agonist. Isoprenaline has potent peripheral vasodilator, bronchodilator, and cardiac stimulating activities. Isoprenaline can be used for the research of bradycardia and bronchial asthma .

HY-108353A

Isoprenaline hemisulfate Maximum Cited Publications 87 Publications Verification	Cardiovascular Disease Alkaloids Classification of Application Fields Other Alkaloids Phenols Polyphenols Endogenous metabolite Disease Research Fields Endocrinology Source Classification	Adrenergic Receptor Endogenous Metabolite
Isoprenaline hemisulfate is a non-selective, orally active **β-adrenergic receptor** agonist. Isoprenaline has potent peripheral vasodilator, bronchodilator, and cardiac stimulating activities. Isoprenaline can be used for the research of bradycardia and bronchial asthma .

HY-B0468R

Isoprenaline hydrochloride (Standard) Isoproterenol hydrochloride (Standard)	Structural Classification Alkaloids Other Alkaloids Phenols Polyphenols Endogenous metabolite Source Classification	Reference Standards Adrenergic Receptor Endogenous Metabolite
Isoprenaline (hydrochloride) (Standard) is the analytical standard of Isoprenaline (hydrochloride). This product is intended for research and analytical applications. Isoprenaline (Isoproterenol) hydrochloride is a non-selective, orally active β-adrenergic receptor agonist. Isoprenaline has potent peripheral vasodilator, bronchodilator, and cardiac stimulating activities. Isoprenaline can be used for the research of bradycardia and bronchial asthma .

HY-113320R

Etiocholanolone (Standard) 5β-Androsterone (Standard)	Structural Classification Microorganisms Endogenous metabolite Steroids Source Classification	Reference Standards GABA Receptor Endogenous Metabolite
Cimbuterol (Standard) is the analytical standard of Cimbuterol. This product is intended for research and analytical applications. Cimbuterol is a β-adrenergic receptor agonist .

Cat. No.	Product Name	Chemical Structure

HY-131104AS

Brombuterol-d9 hydrochloride
Brombuterol-d₉ (hydrochloride) is a deuterium labeled Brombuterol hydrochloride. Brombuterol hydrochloride is a β-adrenergic receptor agonist .

HY-B1421S

Ractopamine-d6 hydrochloride

Ractopamine-d₆ (LY031537-d₆) hydrochloride is the deuterium labeled Ractopamine hydrochloride (HY-B1421). Ractopamine (LY031537) hydrochloride is a potent β-adrenergic receptor (βAR) agonist with K_d values of ~25 nM for pig β₁AR and β₂AR. Ractopamine hydrochloride is linked to protein metabolism. Ractopamine hydrochloride can be used for researching to increase lean tissue growth and improve production efficiency in pigs .

HY-131104S

Brombuterol-d9
Brombuterol-d₉ is a deuterium labeled Brombuterol. Brombuterol is a β-adrenergic receptor agonist .

HY-B0468S

Isoprenaline-d7 hydrochloride
Isoprenaline-d7 (hydrochloride) is a deuterated labeled Isoprenaline (hydrochloride) . Isoprenaline (Isoproterenol) hydrochloride is a non-selective, orally active **β-adrenergic receptor** agonist. Isoprenaline has potent peripheral vasodilator, bronchodilator, and cardiac stimulating activities. Isoprenaline can be used for the research of bradycardia and bronchial asthma .

HY-B1270S

Isoxsuprine-d6 hydrochloride
Isoxsuprine-d₆ (hydrochloride) is the deuterium labeled Isoxsuprine hydrochloride. Isoxsuprine hydrochloride is a beta-adrenergic receptor agonist with Kis of 13.65 μΜ and 3.48 μΜ for myometrial and placcntal beta-adrenergic receptor, respectively. Isoxsuprine hydrochloride is also a NMDA receptor antagonist.

HY-100935S

Cimaterol-d7
Cimaterol-d₇ is the deuterium labeled Cimaterol. Cimaterol is a potent agonist of β-adrenergic receptors (pEC50s=8.13, 8.78, and 6.62 for human β1, β2, and β3, respectively). Cimaterol has been used in farmed animals to increase carcass mass and to alter muscle and fat deposition.

HY-W751276

Ractopamine-13C6

Ractopamine- ¹³C₆ is the ¹³C-labeled Ractopamine (HY-113781). Ractopamine (LY031537 free base) is a potent and orally active β-adrenergic receptor (βAR) agonist with K_d value of ~25 nM for pig β1AR and β2AR. Ractopamine also is a mTAAR1 agonist with an EC₅₀ of 16 μM. Ractopamine promotes muscle mass development, limits fat deposition, reduces feed consumption, increases total cellular protein synthesis, and improves growth rate and feed efficiency in finishing swine. Ractopamine can be used for researching to increase lean tissue growth and improve production efficiency in pigs .

HY-W751275

Ractopamine-13C2

Ractopamine- ¹³C₂ is the ¹³C-labeled Ractopamine (HY-113781). Ractopamine (LY031537 free base) is a potent and orally active β-adrenergic receptor (βAR) agonist with K_d value of ~25 nM for pig β1AR and β2AR. Ractopamine also is a mTAAR1 agonist with an EC₅₀ of 16 μM. Ractopamine promotes muscle mass development, limits fat deposition, reduces feed consumption, increases total cellular protein synthesis, and improves growth rate and feed efficiency in finishing swine. Ractopamine can be used for researching to increase lean tissue growth and improve production efficiency in pigs .

HY-113781S

Ractopamine-d6

Ractopamine-d₆ is the deuterium labeled Ractopamine (HY-113781). Ractopamine (LY031537) hydrochloride is a potent β-adrenergic receptor (βAR) agonist with K_d values of ~25 nM for pig β₁AR and β₂AR. Ractopamine hydrochloride is linked to protein metabolism. Ractopamine hydrochloride can be used for researching to increase lean tissue growth and improve production efficiency in pigs .

HY-B1421S1

Ractopamine-d9 hydrochloride

Ractopamine-d₉ (LY031537-d₉) hydrochloride is the deuterium labeled Ractopamine hydrochloride (HY-B1421). Ractopamine (LY031537) hydrochloride is a potent β-adrenergic receptor (βAR) agonist with K_d values of ~25 nM for pig β₁AR and β₂AR. Ractopamine hydrochloride is linked to protein metabolism. Ractopamine hydrochloride can be used for researching to increase lean tissue growth and improve production efficiency in pigs .

HY-B1421S3

Ractopamine-d5 hydrochloride

Ractopamine-d₅ (LY031537-d₅) hydrochloride is the deuterium labeled Ractopamine hydrochloride (HY-B1421). Ractopamine (LY031537) hydrochloride is a potent β-adrenergic receptor (βAR) agonist with K_d values of ~25 nM for pig β₁AR and β₂AR. Ractopamine hydrochloride is linked to protein metabolism. Ractopamine hydrochloride can be used for researching to increase lean tissue growth and improve production efficiency in pigs .

HY-B1421S2

Ractopamine-d3 hydrochloride

Ractopamine-d₃ (LY031537-d₃) hydrochloride is the deuterium labeled Ractopamine hydrochloride (HY-B1421). Ractopamine hydrochloride (LY031537) is a potent and orally active β-adrenergic receptor (βAR) agonist with K_d value of ~25 nM for pig β1AR and β2AR. Ractopamine hydrochloride also is a mTAAR1 agonist with an EC₅₀ of 16 μM. Ractopamine hydrochloride promotes muscle mass development, limits fat deposition, reduces feed consumption, increases total cellular protein synthesis, and improves growth rate and feed efficiency in finishing swine. Ractopamine hydrochloride can be used for researching to increase lean tissue growth and improve production efficiency in pigs .

Inquiry Online

Your information is safe with us. * Required Fields.

MCE Japan Authorized Agent ナミキ商事株式会社コスモ・バイオ株式会社重松貿易株式会社
Salutation			Country or Region *
Applicant Name *			Organization Name *
Department *
Email Address *			Product Name *
Cat. No.			Requested quantity *
Phone Number *
Remarks