Ractopamine-d5 hydrochloride
Ractopamine-d5 (LY031537-d5) hydrochloride is the deuterium labeled Ractopamine hydrochloride (HY-B1421). Ractopamine (LY031537) hydrochloride is a potent β-adrenergic receptor (βAR) agonist with Kd values of ~25 nM for pig β1AR and β2AR. Ractopamine hydrochloride is linked to protein metabolism. Ractopamine hydrochloride can be used for researching to increase lean tissue growth and improve production efficiency in pigs.
For research use only. We do not sell to patients.
- CAS No.: 3072709-33-9
- Formula: C18H19D5ClNO3
- Molecular Weight:342.87
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All Adrenergic Receptor Isoforms
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Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 3072709-33-9
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Unlabeled Cas 90274-24-1
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Molecular Weight 342.87
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Formula C18H19D5ClNO3
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SMILES
OC(CNC(C)CCC1=C([2H])C([2H])=C(O)C([2H])=C1[2H])([2H])C2=CC=C(O)C=C2.Cl
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Synonyms
LY031537-d5
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Athayde NB, et al. Stress susceptibility in pigs supplemented with ractopamine. J Anim Sci. 2013;91(9):4180-4187. [Content Brief]
[2]. Anderson PT, et al. Ractopamine increases total and myofibrillar protein synthesis in cultured rat myotubes. J Nutr. 1990;120(12):1677-1683. [Content Brief]
[4]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)