1. GPCR/G Protein
    Neuronal Signaling
  2. Adrenergic Receptor
  3. Isoetharine mesylate

Isoetharine mesylate (Synonyms: Isoetarine mesylate)

Cat. No.: HY-B1481
Handling Instructions

Isoetharine (Isoetarine) mesylate is an orally active selective agonist of β-adrenergic receptors. Isoetharine mesylate is a catechol-like drug and catechol O-methyltransferase (COMT) mediates its methylation. Isoetharine mesylate can promote the production of cAMP which stimulates the relaxation of smooth muscle cells and can be used as an emphysema, bronchitis and bronchodilator.

For research use only. We do not sell to patients.

Isoetharine mesylate Chemical Structure

Isoetharine mesylate Chemical Structure

CAS No. : 7279-75-6

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Description

Isoetharine (Isoetarine) mesylate is an orally active selective agonist of β-adrenergic receptors. Isoetharine mesylate is a catechol-like drug and catechol O-methyltransferase (COMT) mediates its methylation. Isoetharine mesylate can promote the production of cAMP which stimulates the relaxation of smooth muscle cells and can be used as an emphysema, bronchitis and bronchodilator[1][2].

In Vitro

Isoetharine mesylate (50 μM, 18 hours) can induce the production and release of [35S]sulfated metabolites of catecholic drugs in HepG2 human hepatoma cells[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Isoetharine mesylate inhibits melanin deposition with the AC50 value of 5.10 mM and complete inhibition of pigment production at 7.50 mM in the zebrafish larvae model[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

335.42

Formula

C14H25NO6S

CAS No.
SMILES

CS(=O)(O)=O.OC1=CC(C(O)C(NC(C)C)CC)=CC=C1O

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
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Isoetharine mesylate
Cat. No.:
HY-B1481
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