7279-75-6
Chemical Structure
Isoetharine mesylate
Synonym(s): Isoetarine mesylate
- CAS No.: 7279-75-6
- Formula:C14H25NO6S
- Molecular Weight:335.42
IUPAC Name: 4-(1-hydroxy-2-(isopropylamino)butyl)benzene-1,2-diol methanesulfonate
InChIKey: SOYAGMVKMXZVNZ-UHFFFAOYSA-N
SMILES: CS(=O)(O)=O.OC1=CC(C(O)C(NC(C)C)CC)=CC=C1O
Biological Activity: Isoetharine (Isoetarine) mesylate is an orally active selective agonist of β-adrenergic receptors. Isoetharine mesylate is a catechol-like agent and catechol O-methyltransferase (COMT) mediates its methylation. Isoetharine mesylate can promote the production of cAMP which stimulates the relaxation of smooth muscle cells and can be used as an emphysema, bronchitis and bronchodilator[1][2].
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Isoetharine mesylate | 99.48% | Isoetharine (Isoetarine) mesylate is an orally active selective agonist of β-adrenergic receptors. Isoetharine mesylate is a catechol-like agent and catechol O-methyltransferase (COMT) mediates its methylation. Isoetharine mesylate can promote the production of cAMP which stimulates the relaxation of smooth muscle cells and can be used as an emphysema, bronchitis and bronchodilator. | ||||||||||||||||||||
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Similarity Score 0.89
HY-B1481AIsoetharine -
Similarity Score 0.89
HY-B1481BIsoetharine hydrochloride -
Similarity Score 0.72
HY-B0468Isoprenaline hydrochloride -
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HY-B1670A(-)-Isoproterenol hydrochloride -
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HY-W722221Colterol acetate -
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HY-128510AColterol hydrochloride -
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HY-128510Colterol -
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HY-B1276Metaproterenol hemisulfate -
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HY-13458ADroxidopa hydrochloride -
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References
- [1]. Katsuhisa Kurogi，et al. Concerted actions of the catechol O-methyltransferase and the cytosolic sulfotransferase SULT1A3 in the metabolism of catecholic drugs. Biochem Pharmacol. 2012 Nov 1;84(9):1186-95. [Content Brief]
- [2]. Monika Maciag，et al. Evaluation of β-adrenergic ligands for development of pharmacological heart failure and transparency models in zebrafish. Toxicol Appl Pharmacol. 2022 Jan 1;434:115812. [Content Brief]
