Ractopamine-d3 (hydrochloride)
Based on 1 Customer Validation
Ractopamine-d3 (LY031537-d3) hydrochloride is the deuterium labeled Ractopamine hydrochloride (HY-B1421). Ractopamine hydrochloride (LY031537) is a potent and orally active β-adrenergic receptor (βAR) agonist with Kd value of ~25 nM for pig β1AR and β2AR. Ractopamine hydrochloride also is a mTAAR1 agonist with an EC50 of 16 μM. Ractopamine hydrochloride promotes muscle mass development, limits fat deposition, reduces feed consumption, increases total cellular protein synthesis, and improves growth rate and feed efficiency in finishing swine. Ractopamine hydrochloride can be used for researching to increase lean tissue growth and improve production efficiency in pigs.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Reinheit : 98.30%
- CAS. Nr.: 1219794-72-5
- Formel: C18H21D3ClNO3
- Molecular Weight:340.86
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Speicherung:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
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Biologische Aktivität
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Chemical Information
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Biologische Aktivität
Beschreibung
In Vitro
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
Anwendung
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS. Nr. 1219794-72-5
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Unlabeled CAS 90274-24-1
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Appearance Solid
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Molecular Weight 340.86
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Formel C18H21D3ClNO3
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Color White to off-white
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SMILES
OC(C=C1)=CC=C1CCC(C)NC([2H])([2H])C(C2=CC=C(C=C2)O)([2H])O.Cl
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Synonyms
LY031537-d3
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Reinheit & Dokumentation
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Data Sheet (267 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
Verweise
[1]. Athayde NB, et al. Stress susceptibility in pigs supplemented with ractopamine. J Anim Sci. 2013;91(9):4180-4187. [Content Brief]
[2]. Anderson PT, et al. Ractopamine increases total and myofibrillar protein synthesis in cultured rat myotubes. J Nutr. 1990;120(12):1677-1683. [Content Brief]
[4]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Ractopamine-d3 (hydrochloride) Related Classifications
HY-B1421S2 Related Classifications
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