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Results for "

2,2'-isomer)

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Drug Isomer (25) 5-HT Receptor (1) AMPK (1) Apoptosis (4) Autophagy (3) Bcl-2 Family (4) Biochemical Assay Reagents (11) Cannabinoid Receptor (4) Carnitine Palmitoyltransferase (CPT) (1) Caspase (1) CaSR (1) CDK (1) COX (3) DGK (1) Dipeptidyl Peptidase (2) Dopamine Receptor (1) Drug Derivative (1) Drug Intermediate (2) Drug Metabolite (2) Endogenous Metabolite (4) Fatty Acid Synthase (FASN) (1) Free Fatty Acid Receptor (1) Fungal (1) Histone Demethylase (1) Histone Methyltransferase (1) HIV (1) Interleukin Related (1) Isocitrate Dehydrogenase (IDH) (1) Isotope-Labeled Compounds (1) MARK (1) MetAP (1) mGluR (1) MMP (2) MOFs (1) Monoamine Oxidase (1) Myosin (1) Na+/H+ Exchanger (NHE) (1) Neurokinin Receptor (2) NF-κB (2) Phosphodiesterase (PDE) (1) PPAR (2) Prostaglandin Receptor (1) PROTACs (2) Protein Arginine Deiminase (2) Ras (1) Reference Standards (2) Salt-inducible Kinase (SIK) (1) SARS-CoV (1) Src (1) Tie (1) TRP Channel (1) VEGFR (1)
By Research Areas:	Cancer (20) Cardiovascular Disease (3) Endocrinology (1) Infection (3) Inflammation/Immunology (3) Metabolic Disease (10) Neurological Disease (29)

By Targets:

Drug Isomer (25)

5-HT Receptor (1)

AMPK (1)

Apoptosis (4)

Autophagy (3)

Bcl-2 Family (4)

Biochemical Assay Reagents (11)

Cannabinoid Receptor (4)

Carnitine Palmitoyltransferase (CPT) (1)

Caspase (1)

CaSR (1)

CDK (1)

COX (3)

DGK (1)

Dipeptidyl Peptidase (2)

Dopamine Receptor (1)

Drug Derivative (1)

Drug Intermediate (2)

Drug Metabolite (2)

Endogenous Metabolite (4)

Fatty Acid Synthase (FASN) (1)

Free Fatty Acid Receptor (1)

Fungal (1)

Histone Demethylase (1)

Histone Methyltransferase (1)

HIV (1)

Interleukin Related (1)

Isocitrate Dehydrogenase (IDH) (1)

Isotope-Labeled Compounds (1)

MARK (1)

MetAP (1)

mGluR (1)

MMP (2)

MOFs (1)

Monoamine Oxidase (1)

Myosin (1)

Na+/H+ Exchanger (NHE) (1)

Neurokinin Receptor (2)

NF-κB (2)

Phosphodiesterase (PDE) (1)

PPAR (2)

Prostaglandin Receptor (1)

PROTACs (2)

Protein Arginine Deiminase (2)

Ras (1)

Reference Standards (2)

Salt-inducible Kinase (SIK) (1)

SARS-CoV (1)

Src (1)

Tie (1)

TRP Channel (1)

VEGFR (1)

By Research Areas:

Cancer (20)

Cardiovascular Disease (3)

Endocrinology (1)

Infection (3)

Inflammation/Immunology (3)

Metabolic Disease (10)

Neurological Disease (29)

Inhibitors & Agonists

Biochemical Assay Reagents

Peptides

Natural
Products

Isotope-Labeled Compounds

Targets Recommended: Drug Isomer

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-103641

(2R)-Octyl-α-hydroxyglutarate 3 Publications Verification (2R)-Octyl-2-HG	Drug Isomer	Cancer
(2R)-Octyl-α-hydroxyglutarate ((2R)-Octyl-2-HG) is a modified form of D-isomer 2-Hydroxyglutarate.

HY-W087952

(R)-(-)-2-Butanol	Drug Intermediate	Endocrinology
(R)-(-)-2-Butanol is the isomer of 2-Butanol, which is found in the females of the white grub beetle, Dasylepida ishigakiensis, to attract males. (R)-(-)-2-Butanol is an intermediate of pharmaceutical synthesis by coupling .

HY-113381A

(R)-2-Hydroxybutanoic acid (R)-α-Hydroxybutyric acid	Drug Isomer	Metabolic Disease
(R)-2-Hydroxybutanoic acid is the isomer of 2-Hydroxybutyric acid (HY-113381), and can be used as an experimental control. 2-Hydroxybutyric acid (α-Hydroxybutyric acid ) is converted from 2-Aminobutyric acid, with 2-oxobutyric acid as an intermediate metabolite .

HY-W015302

2-Aminobenzenesulfonic acid Orthanilic acid; 2-Aminobenzenesulphonic acid	Drug Intermediate	Others
2-Aminobenzenesulfonic acid is an anilinesulfonic acid and also the ortho-isomer of aminobenzenesulfonic acid. 2-Aminobenzenesulfonic acid can be used in the synthesis of other active compounds. 2-Aminobenzenesulfonic acid can coordinate via its -NH₂ and -SO₃ groups to form polymeric copper (II) complexes .

HY-103641A

(2S)-Octyl-α-hydroxyglutarate 2 Publications Verification (2S)-Octyl-2-HG	Drug Isomer	Cancer
(2S)-Octyl-α-hydroxyglutarate ((2S)-Octyl-2-HG) is a modified form of S-isomer 2-Hydroxyglutarate.

HY-N7864

Osbond acid all-cis-4,7,10,13,16-Docosapentaenoic acid	Biochemical Assay Reagents	Others
Docosapentaenoic acid (DPA) is a 22-carbon fatty acid found in fish oil. It is a minor component of total serum unsaturated fatty acids in humans, ranging from 0.1% to 1%, and increasing with dietary supplementation. all-cis-4,7,10,13,16-DPA, also known as Austrian acid, is an isomer of DPA. It is an omega-6 fatty acid formed by the extension and desaturation of arachidonic acid. During fatty acid desaturase syndrome, levels of this fatty acid may be reduced, which may affect development. Upregulated hepatic elongate expression of very long fatty acid protein 6 and elevated levels of very long chain fatty acids, including all-cis 4,7,10,13,16-DPA, are characteristic of nonalcoholic steatohepatitis, a precancerous disease of hepatocellular carcinoma.

HY-15464

(R)-(-)-Gossypol 3 Publications Verification AT-101; R-(-)-gossypol acetic acid	Bcl-2 Family Autophagy	Cancer
(R)-(-)-Gossypol (AT-101) is the levorotatory isomer of a natural product Gossypol. AT-101 is determined to bind to *Bcl-2, Mcl-1* and Bcl-xL proteins with K_is of 260±30 nM, 170±10 nM, and 480±40 nM, respectively.

HY-15464A

(R)-(-)-Gossypol acetic acid Maximum Cited Publications 6 Publications Verification AT-101 (acetic acid); (-)-Gossypol acetic acid; (R)-Gossypol acetic acid	Bcl-2 Family Autophagy	Cancer
(R)-(-)-Gossypol acetic acid (AT-101 (acetic acid)) is the levorotatory isomer of a natural product Gossypol. AT-101 is determined to bind to *Bcl-2, Mcl-1* and Bcl-xL proteins with K_is of 260±30 nM, 170±10 nM, and 480±40 nM, respectively.

HY-W010341

2-Pyridinecarbohydrazide	Biochemical Assay Reagents	Others
2-Pyridinecarbohydrazide is a versatile heterocyclic building block widely used in medicinal chemistry and coordination chemistry, and it finds extensive applications in various synthetic fields. 2-Pyridinecarbohydrazide reacts with the reducing end of carbohydrates to enhance mass spectrometry ionization efficiency, enabling isomer-specific identification of monosaccharides, disaccharides, ketoses/aldoses, and quantitative mass spectrometry imaging of biological tissues .

HY-121638A

(5Z,2E)-CU-3 1 Publications Verification	DGK Apoptosis Interleukin Related Caspase	Cancer
(5Z,2E)-CU-3 is an isomer of CU-3 (HY-121638). CU-3 is a DGKα inhibitor with an IC₅₀ of 0.6 μM. CU-3 competitively reduces DGKα’s affinity for ATP via binding to the enzyme’s catalytic region. CU-3 induces apoptosis in cancer cells. CU-3 promotes T-cell activation and enhances *IL-2* production. CU-3 can be used for the research of hepatocellular carcinoma and cervical cancer .

HY-109167

Aramisulpride (R)-Amisulpride; (R)-Esamisulpride; (R)-DAN 2163	Dopamine Receptor 5-HT Receptor	Neurological Disease
Aramisulpride (R-(+)-Amisulpride) is the R-isomer of Amisulpride (HY-14545). Aramisulpride is a 5-HT₇ receptor antagonist with a K_i value of 22 nM. Aramisulpride is a D₂/D₃ receptor antagonist with a K_i value of 140 nM for D₂R and a K_i value of 13.9 nM for D₃R. Aramisulpride can be used in psychiatric research .

HY-15464D

(S)-Gossypol (acetic acid) 4 Publications Verification (S)-(+)-Gossypol acetic acid	Bcl-2 Family	Cancer
(S)-Gossypol is the isomer of a natural product Gossypol. (S)-Gossypol binds to the BH3-binding groove of Bcl-xL and *Bcl-2* proteins with high affinity.

HY-W007978

(R)-[1,1'-Binaphthalene]-2,2'-diamine R-(-)-2,2-Diamino-1,1-binaphthyl	Biochemical Assay Reagents	Others
(R)-[1,1'-Binaphthalene]-2,2'-diamine is the isomer of (S)-[1,1'-Binaphthalene]-2,2'-diamine (HY-W007978A), and can be used as an experimental control. (S)-[1,1'-Binaphthalene]-2,2'-diamine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-12940A

(S)-GLPG0974	Free Fatty Acid Receptor	Metabolic Disease
(S)-GLPG0974 is the isomer of GLPG0974 (HY-12940), and can be used as an experimental control. GLPG0974 is a *free fatty acid receptor-2* (FFA2/GPR43) antagonist with an IC₅₀** of 9 nM.

HY-141877B

*MS4322 (isomer)* YS43-22 (isomer)	PROTACs Histone Methyltransferase	Cancer
MS4322 (YS43-22) isomer is an isomer of MS4322. MS4322 is a specific PRMT5 PROTAC degrader. MS4322 reduces the PRMT5 protein level with a DC₅₀ of 1.1 μM in MCF-7 cells. MS4322 inhibits the methyltransferase activity of PRMT5 with an IC₅₀ of 18 nM. MS4322 promotes ubiquitination and degradation of PRMT5. MS4322 can be used for the research of breast cancer, lung cancer, and hepatocellular cancer. (Pink: PRMT5 ligand (HY-173092); Blue: E3 ligase ligand HY-112078); Black: linker (HY-124780); E3+linker (HY-173093 )) .

HY-70059A

(Rac)-LY341495	mGluR	Neurological Disease
(Rac)-LY341495 is the isomers of LY341495 (HY-70059) can be used as control compounds in experiments. LY341495 is a metabotropic glutamate receptor (mGluR) antagonist with IC₅₀s of 21 nM, 14 nM, 7.8 μM, 8.2 μM, 170 nM, 990 nM, 22 μM for mGlu2, mGlu3, mGlu1a, mGlu5a, mGlu8, mGlu7, and mGlu4 receptors, respectively .

HY-133016A

(R)-M8891	MetAP	Others
(R)-M8891 (compound R-9) is a less active isomer of M8891. M8891 is an orally active, reversible and brain penetrant Methionine Aminopeptidase-2 (MetAP-2) inhibitor .

HY-120623

BMS-284640	Na+/H+ Exchanger (NHE)	Neurological Disease
BMS-284640 is a synthetic sodium hydrogen exchange isomer-1 (NHE-1) inhibitor. BMS-284640 has a more than 380-fold higher NHE-1 inhibitory activity (IC50: 9 nM) compared to cariporide (HY-19693) and is more selective for NHE-1 over *NHE-2 (IC50: 1.8 μM) and NHE*-5 (IC50: 3.36 μM). BMS-284640 and its analogs also exhibit enhanced oral bioavailability and prolonged plasma half-life in rats. .

HY-103320B

(1R,2R)-Calhex 231 hydrochloride	CaSR	Metabolic Disease
(1R,2R)-Calhex 231 hydrochloride is the isomer of Calhex 231 hydrochloride (HY-103320A), and can be used as an experimental control. Calhex 231 hydrochloride is a CaSR inhibitor via negative allosteric modulation. Calhex 231 hydrochloride blocks Ca ²⁺-induced accumulation of [ ³H]inositol phosphate with an IC₅₀ of 0.39 μM in HEK293 cells. Calhex 231 hydrochloride has the potential for diabetic cardiomyopathy (DCM) treatment .

HY-165116

1-1(Z)-Octadecenyl-2-docosahexaenoyl-sn-glycero-3-PE 18:0p/22:6-PE; C18(Plasm)-22:6-PE; PE(P-18:0/22:6)	Endogenous Metabolite	Others
1-1(Z)-Octadecenyl-2-docosahexaenoyl-sn-glycero-3-PE (18:0p/22:6-PE) is a lipid identified in rat brain tissue by mass spectrometry imaging with specific structural and distribution characteristics, and isomers of different fatty acid chains can be identified by improved methods.

HY-128603

2-Hydroxyisobutyryl-CoA	Biochemical Assay Reagents	Metabolic Disease
2-Hydroxyisobutyryl-CoA is a hydroxy fatty acyl-CoA. 2-Hydroxyisobutyryl-CoA mutase forms the isomer (S)-3-hydroxybutyryl-CoA .

HY-148516A

(R)-MPH-220	Myosin	Neurological Disease
(R)-MPH-220 is the R isomer of MPH-220 (HY-148516). MPH-220 is a selective and orally active inhibitor of skeletal muscle *myosin-2*. MPH-220 enables muscle relaxation. MPH-220 is anti-spastic agent that can be used in the research of spasticity and muscle stiffness .

HY-160431

8(9)-EET	PPAR NF-κB COX Drug Metabolite	Metabolic Disease
8(9)-EET is one of the main metabolites produced by the metabolism of arachidonic acid (HY-109590) through the cytochrome P450 epoxide pathway. 8(9)-EET is an effective substrate for COX-1 and *COX-2. 8(9)-EET activates PPARα* in HEK293 cells and inhibits the activity of NF-κB induced by IL-1β in a PPARα-dependent and -independent manner. The (8S,9R)-isomer of 8(9)-EET ([(8S,9R)-EET]) causes vasoconstriction, thereby reducing renal plasma flow and glomerular filtration rate .

HY-120877A

(R)-MRT199665	MARK Salt-inducible Kinase (SIK) AMPK Apoptosis	Cancer
(R)-MRT199665 is an isomer of MRT199665 (HY-120877). MRT199665 is a potent and ATP-competitive, selective MARK/SIK/AMPK inhibitor with IC₅₀s of 2/2/3/2 nM, 10/10 nM, and 110/12/43 nM for MARK1/MARK2/MARK3/MARK14, AMPKα1/AMPKα2, and SIK1/SIK2/SIK3, respectively. MRT199665 causes apoptosis in MEF2C-activated human acute myeloid leukemias (AML) cells. MRT199665 inhibits the phosphorylation of SIK substrate CRTC3 at S370 .

HY-101704

Y1 receptor antagonist 1 H 409-22 (isomer)	Neurokinin Receptor	Cardiovascular Disease Neurological Disease
Y1 receptor antagonist 1 (H 409-22 isomer) (Example 4) is a neuropeptide Y1 receptor antagonist. Y1 receptor antagonist 1 can be used for the study of cardiovascular diseases, such as vasoconstriction .

HY-W007978B

1,1'-Binaphthyl-2,2'-diamine 2,2'-Diamino-1,1'-dinaphthyl	MOFs	Others
1,1'-Binaphthyl-2,2'-diamine is the isomer of (S)-[1,1'-Binaphthalene]-2,2'-diamine (HY-W007978A), and can be used as an experimental control. (S)-[1,1'-Binaphthalene]-2,2'-diamine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-172042

PB-22 7-Hydroxyquinoline isomer	Drug Isomer	Neurological Disease
PB-22 7-Hydroxyquinoline isomer is a structural isomer of PB-22. PB-22 is a cannabinoid.

HY-172053

PB-22 8-Hydroxyisoquinoline isomer	Drug Isomer	Neurological Disease
PB-22 8-Hydroxyisoquinoline isomer is a structural isomer of PB-22. PB-22 is a cannabinoid.

HY-172040

PB-22 5-Hydroxyquinoline isomer	Drug Isomer	Neurological Disease
PB-22 5-hydroxyquinoline isomer is a structural isomer of PB-22. PB-22 is a cannabinoid.

HY-172051

PB-22 6-Hydroxyisoquinoline isomer	Drug Isomer	Neurological Disease
PB-22 6-Hydroxyisoquinoline isomer is a structural isomer of PB-22. PB-22 is a cannabinoid.

HY-172050

PB-22 5-Hydroxyisoquinoline isomer	Drug Isomer	Neurological Disease
PB-22 5-Hydroxyisoquinoline isomer is a structural isomer of PB-22. PB-22 is a cannabinoid.

HY-172041

PB-22 6-Hydroxyquinoline isomer	Drug Isomer	Neurological Disease
PB-22 6-Hydroxyquinoline isomer is a structural isomer of PB-22. PB-22 is a cannabinoid.

HY-172052

PB-22 7-Hydroxyisoquinoline isomer	Drug Isomer	Neurological Disease
PB-22 7-Hydroxyisoquinoline isomer is a structural isomer of PB-22. PB-22 is a cannabinoid.

HY-172048

5-Fluoro PB-22 6-hydroxyisoquinoline isomer	Drug Isomer	Neurological Disease
5-Fluoro PB-22 6-hydroxyisoquinoline isomer is a structural isomer of 5-Fluoro PB-22.

HY-172047

5-Fluoro PB-22 5-hydroxyisoquinoline isomer	Drug Isomer	Neurological Disease
5-Fluoro PB-22 5-hydroxyisoquinoline isomer is a structural isomer of 5-Fluoro PB-22.

HY-172049

5-Fluoro PB-22 7-hydroxyisoquinoline isomer	Drug Isomer	Neurological Disease
5-Fluoro PB-22 7-hydroxyisoquinoline isomer is a structural isomer of 5-Fluoro PB-22.

HY-172036

5-Fluoro PB-22 6-hydroxyquinoline isomer	Drug Isomer	Neurological Disease
5-Fluoro PB-22 N-(3-fluoropentyl) isomer is a structural isomer of 5-Fluoro PB-22.

HY-172044

5-Fluoro PB-22 N-(3-fluoropentyl) isomer	Drug Isomer	Neurological Disease
5-Fluoro PB-22 N-(3-fluoropentyl) isomer is a structural isomer of 5-Fluoro PB-22.

HY-172045

5-Fluoro PB-22 N-(4-fluoropentyl) isomer	Drug Isomer	Neurological Disease
5-Fluoro PB-22 N-(4-fluoropentyl) isomer is a structural isomer of 5-Fluoro PB-22.

HY-W093104

(S)-(-)-2-Methylbutanol (S)-2-Methyl-1-butanol	Endogenous Metabolite	Others
(S)-(-)-2-Methylbutanol is a S-isomer of 2-Methylbutanol .

HY-172035

5-Fluoro PB-22 5-hydroxyquinoline isomer	Cannabinoid Receptor	Neurological Disease
5-Fluoro PB-22 5-hydroxyquinoline isomer is a synthetic cannabinoid.

HY-W768607

5-Fluoro PB-22 8-hydroxyisoquinoline isomer	Cannabinoid Receptor	Neurological Disease
5-Fluoro PB-22 8-hydroxyisoquinoline isomer is structurally similar to known synthetic cannabinoids.

HY-N15816

*18:1 BMP (R,R'; 2,2'-isomer) ammonium*	Biochemical Assay Reagents	Others
18:1 BMP (R,R'; 2,2'-isomer) ammonium is a bis(monoacylglycero)phosphate (BMP).

HY-172043

5-Fluoro PB-22 N-(2-fluoropentyl) isomer	Cannabinoid Receptor	Neurological Disease
5-Fluoro PB-22 N-(2-fluoropentyl) isomer is a derivative of cannabinoid.

HY-137516A

LC-2 epimer	PROTACs Ras	Cancer
LC-2 epimer is a differential isomer of LC-2. LC-2 is a mutation-selective PROTAC depressant for KRAS and contains a ligand for the von Hippel Lindau E3 ligase linked to the KRAS inhibitor MRTX849 .

HY-113381B

(R)-2-Hydroxybutanoic acid sodium (R)-α-Hydroxybutyric acid sodium	Endogenous Metabolite Drug Isomer	Others
(R)-2-Hydroxybutanoic acid ((R)-α-Hydroxybutyric acid) sodium is the R-isomer of 2-Hydroxybutyric acid (HY-113381), and can be used as an experimental control. 2-Hydroxybutyric acid is converted from 2-Aminobutyric acid, with 2-oxobutyric acid as an intermediate metabolite .

HY-118105

RK-20448	Src VEGFR Tie	Infection Cancer
RK-20448 is an ATP-competitive inhibitor of Lck, Src, KDR/VEGF2R and *Tie-2* with IC₅₀ values of 0.24, 1.19, 10.74 and 5.85 µM, respectively. RK-20448 also inhibits BLK, Csk, Fyn and Lyn with IC₅₀ values of 0.37, 4.27, 2.03 and 0.43 µM, respectively. RK-20448 is the cis isomer of A-419259 (HY-15764) .

HY-101704A

Y1 receptor antagonist 1 formic H 409-22 (isomer formic)	Neurokinin Receptor	Cardiovascular Disease Neurological Disease
Y1 receptor antagonist 1 (H 409-22 isomer) formic (Example 4) is a neuropeptide Y1 receptor antagonist. Y1 receptor antagonist 1 can be used for the study of cardiovascular diseases, such as vasoconstriction .

HY-W015093R

2-(2-(2-Hydroxypropoxy)propoxy)propan-1-ol,(isomers mixture) (Standard) Tripropylene glycol (Standard)	Reference Standards
2-(2-(2-Hydroxypropoxy)propoxy)propan-1-ol,(isomers mixture) (Standard) is the analytical standard of 2-(2-(2-Hydroxypropoxy)propoxy)propan-1-ol,(isomers mixture). This product is intended for research and analytical applications.

HY-12788A

(S)-PF-04449613	Phosphodiesterase (PDE)	Neurological Disease
(S)-PF-04449613 is the left-handed isomer of PF-04449613 (HY-12788). PF-04449613 is a selective PDE9A inhibitor with an IC₅₀ of 22 nM. PF-04449613 improves motor learning ability in a mouse model .

Cat. No.	Product Name	Type

HY-N7864

Osbond acid

all-cis-4,7,10,13,16-Docosapentaenoic acid

Biochemical Assay Reagents

Docosapentaenoic acid (DPA) is a 22-carbon fatty acid found in fish oil. It is a minor component of total serum unsaturated fatty acids in humans, ranging from 0.1% to 1%, and increasing with dietary supplementation. all-cis-4,7,10,13,16-DPA, also known as Austrian acid, is an isomer of DPA. It is an omega-6 fatty acid formed by the extension and desaturation of arachidonic acid. During fatty acid desaturase syndrome, levels of this fatty acid may be reduced, which may affect development. Upregulated hepatic elongate expression of very long fatty acid protein 6 and elevated levels of very long chain fatty acids, including all-cis 4,7,10,13,16-DPA, are characteristic of nonalcoholic steatohepatitis, a precancerous disease of hepatocellular carcinoma.

HY-W776824

2-Phthalimidolactosamine,heptaacetate (mixture of isomers)

Biochemical Assay Reagents

2-Phthalimidolactosamine,heptaacetate (mixture of isomers) is a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It involves carbohydrate chemistry, enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans in biological systems. This field is closely related to basic research, biomedicine, and biotechnology .

Cat. No.	Product Name	Target	Research Area

HY-P5327

r8 Bid BH3	Bcl-2 Family	Others
r8 Bid BH3 is a biological active peptide. (The Bid BH3 is a pro-apoptotic member of the 'BH3-only' subset of BCL-2 family proteins that constitute a critical control point in apoptosis. r8BIDBH3 is lethal to human leukemia cell lines that expresse Bcl-2. The Bcl-2 antagonists may have the potential to be efficacious in cancer therapy. Poly-D-arginine (d-isomer as denoted by rrrrrrrr) is fused to the Bid BH3 peptide to facilitate cellular uptake of the peptide.)

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-W087952

(R)-(-)-2-Butanol	Natural Products Microorganisms Classification of Application Fields Metabolic Disease Disease Research Fields Source Classification	Drug Intermediate
(R)-(-)-2-Butanol is the isomer of 2-Butanol, which is found in the females of the white grub beetle, Dasylepida ishigakiensis, to attract males. (R)-(-)-2-Butanol is an intermediate of pharmaceutical synthesis by coupling .

HY-W015302

2-Aminobenzenesulfonic acid Orthanilic acid; 2-Aminobenzenesulphonic acid	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Drug Intermediate
2-Aminobenzenesulfonic acid is an anilinesulfonic acid and also the ortho-isomer of aminobenzenesulfonic acid. 2-Aminobenzenesulfonic acid can be used in the synthesis of other active compounds. 2-Aminobenzenesulfonic acid can coordinate via its -NH₂ and -SO₃ groups to form polymeric copper (II) complexes .

HY-15464

(R)-(-)-Gossypol 3 Publications Verification AT-101; R-(-)-gossypol acetic acid	Malvaceae Classification of Application Fields Gossypium Phenols Plants Disease Research Fields Cancer Source Classification	Bcl-2 Family Autophagy
(R)-(-)-Gossypol (AT-101) is the levorotatory isomer of a natural product Gossypol. AT-101 is determined to bind to *Bcl-2, Mcl-1* and Bcl-xL proteins with K_is of 260±30 nM, 170±10 nM, and 480±40 nM, respectively.

HY-N15816

*18:1 BMP (R,R'; 2,2'-isomer) ammonium*	Lipid	Biochemical Assay Reagents
18:1 BMP (R,R'; 2,2'-isomer) ammonium is a bis(monoacylglycero)phosphate (BMP).

HY-134211

(Z)-2-Octenoic acid	Classification of Application Fields Ketones, Aldehydes, Acids Other Diseases Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
Z-2-Octenoic acid is the Z-isomer of 2-Octenoic acid. trans-2-Octenoic acid is a metabolite of Mucor species.

HY-N0722A

(Z)-Neochlorogenic acid cis-5-O-Caffeoylquinic acid	Structural Classification Caprifoliaceae Lonicera periclymenum L. Phenols Polyphenols Plants Source Classification	Drug Derivative
(Z)-Neochlorogenic acid is the z-isomer of Neochlorogenic acid (HY-N0722). Neochlorogenic acid is a natural polyphenolic compound found in dried fruits and other plants. Neochlorogenic acid inhibits the production of TNF-α and IL-1β. Neochlorogenic acid suppresses iNOS and COX-2 protein expression. Neochlorogenic acid also inhibits phosphorylated NF-κB p65 and p38 MAPK activation .

HY-N16849

Myristinin A YM 26567-1	Structural Classification Horsfieldia amygdalina (Wall. ex Hook. f. & Thomson) Warb. Coumarins Myristicaceae Phenylpropanoids Plants Source Classification	COX Prostaglandin Receptor Fungal
Myristinin A (YM 26567-1) is a trans-isomer flavan compound found in Horsfieldia amygdaline and Myristica cinnamomea. Myristinin A can selectively inhibit *COX-2* activity with an IC₅₀ of 16.9 μg/mL. Myristinin A can reduce the production of prostaglandin E2 (PGE2) and inhibit phospholipase A2 (PLA2), thereby blocking the release of inflammatory mediators. Myristinin A can inhibit Candida albicans with an IC₅₀ of 8.8 μg/mL. Myristinin A can be used for the research of inflammation and infection, such as rheumatoid arthritis .

Cat. No.	Product Name	Chemical Structure

HY-103641AS1

(2R)-Octyl-α-hydroxyglutarate-d17
(2R)-Octyl-α-hydroxyglutarate-d₁₇ ((2R)-Octyl-2-HG-d₁₇) is deuterium labeled (2R)-Octyl-α-hydroxyglutarate (HY-103641). (2R)-Octyl-α-hydroxyglutarate is a modified form of S-isomer 2-Hydroxyglutarate .

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2,2'-isomer)

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