(R)-[1,1'-Binaphthalene]-2,2'-diamine
Based on 1 Customer Validation
(R)-[1,1'-Binaphthalene]-2,2'-diamine is the isomer of (S)-[1,1'-Binaphthalene]-2,2'-diamine (HY-W007978A), and can be used as an experimental control. (S)-[1,1'-Binaphthalene]-2,2'-diamine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
For research use only. We do not sell to patients.
- Purity: 99.99%
- CAS No.: 18741-85-0
- Formula: C20H16N2
- Molecular Weight:284.35
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Storage:
4°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
![(R)-[1,1'-Binaphthalene]-2,2'-diamine Chemical Structure](https://file.medchemexpress.com/product_pic/hy-w007978.gif "Click to View (R)-[1,1'-Binaphthalene]-2,2'-diamine Chemical Structure")
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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![(S)-[1,1'-Binaphthalene]-2,2'-diamine](https://file.medchemexpress.com/product_pic/hy-w007978a.gif)
HY-W007978A
(S)-[1,1'-Binaphthalene]-2,2'-diamine
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HY-W017757
(R)-BINAP
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HY-Y0003
(Rac)-BINAP
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HY-W040233
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HY-W040233R
L-Lactic acid sodium (Standard)
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HY-W002502
(DHQ)2PHAL
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HY-I0606B
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Biological Activity
Isomers share the same atomic composition but differ in spatial arrangement or connectivity, often exhibiting significant differences in pharmacological activity, toxicity, and physicochemical properties.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 18741-85-0
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Appearance Solid
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Molecular Weight 284.35
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Formula C20H16N2
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Color White to light brown
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SMILES
NC1=C(C2=C(C=CC=C3)C3=CC=C2N)C4=CC=CC=C4C=C1.[R]
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Synonyms
R-(-)-2,2-Diamino-1,1-binaphthyl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
Solvent & Solubility
DMSO : 50 mg/mL (175.84 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Select the appropriate dissolution method based on your experimental animal and administration route.
- For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
- To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for In Vivo experiments, it is recommended to prepare freshly and use it on the same day.
- The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
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%DMSO +
Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
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%+
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+%Tween-80 + +
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%Saline +
The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Working solution concentration: 0.22 mg/mL
Method for preparing stock solution: mg drug dissolved in μL DMSO. Stock solution concentration: mg/mL. * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
1. Take μL DMSO stock solution;
2. Add μL .
μL , mix evenly;
3. Then add μL Tween 80, mix evenly;
4. Then add μL
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
Purity & Documentation
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Data Sheet (301 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
References
[1]. Singh AV, et al. PR-924, a selective inhibitor of the immunoproteasome subunit LMP-7, blocks multiple myeloma cell growth both in vitro and in vivo. Br J Haematol. 2011 Jan;152(2):155-63. [Content Brief]
[2]. Parlati F, et al. Carfilzomib can induce tumor cell death through selective inhibition of the chymotrypsin-like activity of the proteasome. Blood. 2009 Oct 15;114(16):3439-47. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.5168 mL | 17.5840 mL | 35.1679 mL | 87.9198 mL |
| 5 mM | 0.7034 mL | 3.5168 mL | 7.0336 mL | 17.5840 mL | |
| 10 mM | 0.3517 mL | 1.7584 mL | 3.5168 mL | 8.7920 mL | |
| 15 mM | 0.2345 mL | 1.1723 mL | 2.3445 mL | 5.8613 mL | |
| 20 mM | 0.1758 mL | 0.8792 mL | 1.7584 mL | 4.3960 mL | |
| 25 mM | 0.1407 mL | 0.7034 mL | 1.4067 mL | 3.5168 mL | |
| 30 mM | 0.1172 mL | 0.5861 mL | 1.1723 mL | 2.9307 mL | |
| 40 mM | 0.0879 mL | 0.4396 mL | 0.8792 mL | 2.1980 mL | |
| 50 mM | 0.0703 mL | 0.3517 mL | 0.7034 mL | 1.7584 mL | |
| 60 mM | 0.0586 mL | 0.2931 mL | 0.5861 mL | 1.4653 mL | |
| 80 mM | 0.0440 mL | 0.2198 mL | 0.4396 mL | 1.0990 mL | |
| 100 mM | 0.0352 mL | 0.1758 mL | 0.3517 mL | 0.8792 mL |
(R)-[1,1'-Binaphthalene]-2,2'-diamine Related Classifications
HY-W007978 Related Classifications
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