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Cat. No.: HY-W133921

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Dipropylene glycol

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Dipropylene glycol is a mixture of three structural isomers (2-(2-hydroxypropoxy)-1-propanol, 1,1'-oxybis (2-propanol), and 2,2'-oxybis (1-propanol)). Dipropylene glycol induces liver and kidney damage as well as reproductive toxicity in rodents. Dipropylene glycol can be used in chemical industry-related research, such as for plasticizers, polyester resins, cosmetics, fragrances, polyurethane polyols, and alkyd resins.

For research use only. We do not sell to patients.

CAS No.: 25265-71-8
Formula: C₆H₁₄O₃
Molecular Weight:134.18

Storage:

Store at room temperature 3 years.

In solvent -80°C, 2 years , -20°C, 1 year

Dipropylene glycol Chemical Structure

CAS No.: 25265-71-8

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vivo
Chemical Information
Purity & Documentation
References
Calculators
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Classifications
Bioz

Biological Activity

Description

In Vivo

Dipropylene glycol (2500-80,000 ppm; p.o.; ad libitum daily; 2 weeks, 3 months, or 2 years) administered via drinking water causes dose-dependent nonneoplastic toxic effects in F344/N rats, including reduced body weight gain, liver and kidney organ weight changes, histopathological lesions in the liver, kidney, nose, and reproductive tract, and significantly reduced survival (0% survival) in male rats at the 40,000 ppm 2-year dose due to exacerbated chronic nephropathy^[1].
Dipropylene glycol (5000-80,000 ppm; p.o.; ad libitum daily; 2 weeks, 3 months, or 2 years) administered via drinking water causes limited dose-dependent nonneoplastic toxic effects in B6C3F1 mice, including reduced body weight gain, liver organ weight changes, and centrilobular liver hypertrophy at high doses, with no treatment-related lesions observed in the 2-year study, indicating mice are less susceptible to dipropylene glycol toxicity than rats^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 25265-71-8
Appearance Liquid (Density: 1.023 g/cm³)
Molecular Weight 134.18
Formula C₆H₁₄O₃
SMILES

OC(COC(C)CO)C.OC(C)COCC(C)O.OCC(C)OC(C)CO
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Store at room temperature 3 years

In solvent	-80°C	2 years
	-20°C	1 year

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Hooth MJ, et al. Toxicology and carcinogenesis studies of dipropylene glycol in rats and mice. Toxicology. 2004;204(2-3):123-140. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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