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Results for "

DTPA-BSA (Gd)

" in MedChemExpress (MCE) Product Catalog:

By Targets:	ADC Antibody (1) ADC Linker (1) Antibiotic (2) Antibody-Drug Conjugates (ADCs) (1) Apoptosis (8) Bacterial (3) Biochemical Assay Reagents (15) Caspase (3) CD2 (2) CD3 (1) Ceramidase (1) Dipeptidyl Peptidase (1) DNA/RNA Synthesis (1) Drug Intermediate (1) Endogenous Metabolite (4) Enteropeptidase (1) Fluorescent Dye (1) Glucosylceramide Synthase (GCS) (4) Glutathione Peroxidase (1) Glycosidase (3) HSV (1) Isotope-Labeled Compounds (12) LDLR (1) Liposome (1) Mitochondrial Metabolism (3) mRNA (1) mTOR (1) PERK (1) PKA (1) Radionuclide-Drug Conjugates (RDCs) (3) Toll-like Receptor (TLR) (1) Topoisomerase (1) TSH Receptor (2)
By Research Areas:	Cancer (33) Cardiovascular Disease (2) Infection (3) Inflammation/Immunology (7) Metabolic Disease (12) Neurological Disease (17)
Oligonucleotides:	Pegylated Lipids (1) mRNA (1) Phospholipids (1)

Inhibitors & Agonists

Fluorescent Dyes

Biochemical Assay Reagents

Peptides

Inhibitory Antibodies

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-P9933

Dinutuximab APN-311; Ch14.18; MAb-14.18	Apoptosis PERK mTOR	Cancer
Dinutuximab (APN-311) is a chimeric human-mouse *anti-GD2* monoclonal antibody. Dinutuximab can bind to *GD2* on the cell surface, triggering antibody-dependent cell-mediated cytotoxicity and complement-dependent cytotoxicity, and promoting tumor regression. Dinutuximab can inhibit the growth, invasion, and migration and induce apoptosis of tumor cells. Dinutuximab can be used in the research of tumors such as neuroblastoma and breast cancer .

HY-P991202

Anti-TSHR Antibody (M22)	TSH Receptor PKA	Metabolic Disease Inflammation/Immunology
Anti-TSHR Antibody (M22) is a selective agonist targeting TSHR (thyroid-stimulating hormone receptor), acting through competitive binding to the extracellular domain of TSHR. Anti-TSHR Antibody (M22) can mimic the biological effects of thyroid-stimulating hormone (TSH), activating downstream cAMP-PKA and other signaling pathways. Anti-TSHR Antibody (M22) can stimulate the proliferation of thyroid follicular epithelial cells and human umbilical vein endothelial cells (HUVECs), promote angiogenesis and tube formation, cell migration, and also upregulate the expression of angiogenesis-related proteins such as PROX1. Anti-TSHR Antibody (M22) can be used in research areas such as the mechanisms of goiter formation in Graves' disease (GD), angiogenesis regulation, and TSHR antagonist screening .

HY-147976

Glucocerebrosidase-IN-1	Glycosidase	Neurological Disease Metabolic Disease
Glucocerebrosidase-IN-1 (compound 11a) is a potent and selective GCase (glucocerebrosidase) inhibitor, with an IC₅₀ of 29.3 μM and a K_i of 18.5 μM. Glucocerebrosidase-IN-1 can be used for the research of Gaucher disease (GD) and Parkinson’s disease (PD) .

HY-165740

Ganglioside GD2 Disialoganglioside GD2	Apoptosis	Cancer
Ganglioside GD2 (Disialoganglioside GD2) is a tumor-associated antigen. Ganglioside GD2 shows limited expression in normal tissues but is overexpressed in multiple tumor types, and thus can serve as a target in cancer. Ganglioside GD2 is associated with tumor development and malignant phenotypes, and its mechanism of action relies on enhancing cell proliferation, motility, migration, adhesion and invasion, with specific effects depending on the tumor type .

HY-164569

NH2 DOTA-GA	Radionuclide-Drug Conjugates (RDCs)	Cancer
NH2 DOTA-GA is a DOTA-based metal chelator that can be used to prepare radionuclide drug conjugates (RDCs) whose carboxylic acid groups can complex metal ions, for example, NH2 DOTA-GA complexes Gd(III) ions.

HY-158109

M3554	Antibody-Drug Conjugates (ADCs) CD2 Topoisomerase	Cancer
M3554 is an anti-GD2 antibody-drug conjugate (ADC) based on the humanized anti-GD2 antibody. M3554 consists of the humanized monoclonal antibody hu14.18 (K322A) (HY-P991040) linked to a topoisomerase 1 inhibitor Exatecan (HY-13631) via a cleavable β-glucuronide linker. M3554 can be used for the study of neuroblastoma, osteosarcoma or glioma .

HY-P99757

Nivatrotamab Hu3F8-BSAb	CD2 CD3	Cancer
Nivatrotamab (Hu3F8-BsAb) is a humanized anti-GD2/CD3 bispecific antibody. Nivatrotamab is a CD3- and GD2-specific bsAb-based T-cell engager. Nivatrotamab can be used in research of neuroblastoma .

HY-153213

Org 274179-0	TSH Receptor	Metabolic Disease
Org 274179-0 is a potent and allosteric antagonist of thyroid-stimulating hormone (TSH) receptor, with an IC₅₀ of nanomolar concentration. Org 274179-0 completely inhibits TSH (and TSI)-mediated TSH receptor activation with little effect on the potency of TSH. Org 274179-0 can be used for the research of Graves' disease (GD) .

HY-141866

Acid Ceramidase-IN-1 1 Publications Verification	Ceramidase	Neurological Disease
Acid Ceramidase-IN-1 is orally active and blood-brain barrier penetrant acid ceramidase (AC, ASAH-1) inhibitor (hAC IC₅₀=0.166 μM). Acid Ceramidase-IN-1 reduces AC activity, accumulates ceramide species (Cer (d18:0/16:0), Cer (d18:1/16:0)), and decreases sphingosine levels. Acid Ceramidase-IN-1 can be used for the study of severe neurological lysosomal storage diseases (LSDs) such as Gaucher’s disease (GD) and Krabbe’s disease (KD) .

HY-W747597

Ganglioside GD1b Disodium Salt (Bovine Brain) Disialoganglioside GD1b; Ganglioside C1; Ganglioside G2	Endogenous Metabolite	Cancer
Ganglioside GD1b Disodium Salt (Bovine Brain) (Disialoganglioside GD1b; Ganglioside C1) is an acidic glycosphingolipid containing two sialic acid residues linked to an internal galactose unit. Ganglioside GD1b Disodium Salt tightly packs with cholesterol to form lipid microdomains that modulate intracellular and intercellular signaling events. Concentrations of Ganglioside GD1b Disodium Salt (Bovine Brain) in the human brain increase with age and are positively correlated with pilocytic astrocytoma tumor grade. Ganglioside GD1b Disodium Salt has been detected in various other gliomas, including primitive neuroectodermal tumors, glioblastomas, and anaplastic astrocytomas.

HY-P2660

Gly-Asp-Asp-Asp-Asp-Lys-β-naphthylamide GD4K-na	Enteropeptidase	Others
Gly-Asp-Asp-Asp-Asp-Lys-β-naphthylamide (GD4K-na) is a substrate for human enteropeptidase (K_m: 0.16 mM) .

HY-E70057

alpha-2,8-Sialyltransferase (CstII) 1 Publications Verification ST8Sia VI; GD3 synthase	Endogenous Metabolite	Metabolic Disease
alpha-2,8-Sialyltransferase (CstII) (ST8Sia VI) is a member of alpha2,8-sialyltransferase (ST8Sia) family, is often used in biochemical studies. alpha-2,8-Sialyltransferase (CstII) catalyzes elongation of the α2,8-linked oligo/polysialic acid chain on the Sia residue transferred .

HY-17591S

Penicillin G-d5 potassium Benzylpenicillin-d5 potassium	Isotope-Labeled Compounds Bacterial Antibiotic	Infection
Penicillin G-d₅ (potassium) is the deuterium labeled Penicillin G potassium. Penicillin G potassium is a fast-acting antibiotic; used to treat bacterial infections that affect the blood, heart, lungs, joints, and genital areas .

HY-116392E

D-threo-PDMP	Glucosylceramide Synthase (GCS) Apoptosis	Neurological Disease Metabolic Disease Cancer
D-threo-PDMP is a potent glucoceramide synthase (GCS) inhibitor, which reduces the glycosphingolipids (such as GM3 and *GD3) on the cell surface by inhibiting glycosylation, reduces the total length of the axon plexus and the number of axon branch points, and inhibits neurite growth. D-threo-PDMP inhibits the synthesis of GM3, thereby reducing the adhesion ability of B16 melanoma cells and mimicking the pathological effects of hyperglycemia/TGF-β1. D-threo-PDMP inhibits the synthesis of GD3, thereby protecting liver cells from apoptosis* induced by TNF-α. D-threo-PDMP can be used to study diseases related to targeted glycosphingolipid metabolism .

HY-116392F

D-threo-PDMP hydrochloride	Glucosylceramide Synthase (GCS)	Neurological Disease Metabolic Disease Cancer
D-threo-PDMP hydrochloride is a potent glucoceramide synthase (GCS) inhibitor, which reduces the glycosphingolipids (such as GM3 and *GD3) on the cell surface by inhibiting glycosylation, reduces the total length of the axon plexus and the number of axon branch points, and inhibits neurite growth. D-threo-PDMP hydrochloride inhibits the synthesis of GM3, thereby reducing the adhesion ability of B16 melanoma cells and mimicking the pathological effects of hyperglycemia/TGF-β1. D-threo-PDMP hydrochloride inhibits the synthesis of GD3, thereby protecting liver cells from apoptosis* induced by TNF-α. D-threo-PDMP hydrochloride can be used to study diseases related to targeted glycosphingolipid metabolism .

HY-172699

DSPE-PEG2000-ANG	Liposome LDLR	Cancer
DSPE-PEG2000-ANG is a conjugate of DSPE-PEG2000-MAL and Angiopep-2. Angiopep-2 is a peptide ligand that targets LRP-1. DSPE-PEG2000-ANG is used to synthesize gadolinium-boron bifunctionalized lipid nanoparticles BPA-F&DOTA-Gd@LIPO-ANG with blood-brain barrier and glioma targeting properties .

HY-B2119

Sodium tauroglycocholate Tauroglycocholic acid sodium salt	Biochemical Assay Reagents	Metabolic Disease
Sodium tauroglycocholate (Tauroglycocholic acid sodium salt) is a multifunctional surfactant and penetration enhancer that can serve as a cholegraphic contrast agent. In organic solvents, Sodium tauroglycocholate embeds and stabilizes invertase by forming reverse micelles, and prolongs its active lifespan. In terms of transdermal absorption, Sodium tauroglycocholate effectively regulates the flux of aminophylline through snake slough by binding to keratin filaments, disrupting keratinocytes and altering lipid components of the stratum corneum. It exhibits rapid penetration characteristics without lag time at a concentration of 100 μg/mL. Sodium tauroglycocholate does not interfere with the hepatic uptake of Gd-EOB-DTPA by the bile acid transport system in rat hepatocytes .

HY-131139A

Ganglioside GD3 diammonium	Apoptosis	Neurological Disease Cancer
Ganglioside GD3 diammonium is an acidic glycosphingolipid. Ganglioside GD3 diammonium inhibits the proliferation of cancer cells, affects the opening of the mitochondrial permeability transition pore (PTPC), induces apoptosis and activates caspase family. Ganglioside GD3 diammonium can be used in research about cancer and neurodegenerative diseases .

HY-141569

Ganglioside GD1a	Toll-like Receptor (TLR)	Inflammation/Immunology
Ganglioside GD1a modulates toxic and inflammatory effects of E. coli lipopolysaccharide by preventing TLR4 translocation into lipid rafts. Ganglioside GD1a significantly reduces the effect of LPS on the decrease of cell survival and on stimulation of reactive oxygen species production .

HY-N7139S1

Penicillin G-d7 potassium salt Benzylpenicillin-d7 potassium salt	Antibiotic Bacterial Isotope-Labeled Compounds	Others
Penicillin G-d₇ (potassium) is the deuterium labeled Penicillin G potassium salt .

HY-151240

Galactosylceramide	Endogenous Metabolite	Neurological Disease
Galactosylceramide (GalC) is a galactosylceramide that has been implicated in many physiological and pathological phenomena. For example, important lysosomal storage disorders such as Gaucher disease (GD) and neurodegenerative diseases are characterized by GlcCer accumulation.

HY-P2022

Pentetreotide	Radionuclide-Drug Conjugates (RDCs)	Cancer
Pentetreotide is a diethylenetriaminopentaacetic (DTPA) conjugate of Octreotide (HY-P0036). Pentetreotide is a somatostatin analog that, when labeled with ¹¹¹In, can be used for nuclear medicine imaging. Somatostatin receptor scintigraphy with Pentetreotide is effective in visualizing neuroendocrine tumors, and its metastasis .

HY-157343A

GD3 Ganglioside sodium	Apoptosis Mitochondrial Metabolism Caspase	Neurological Disease Cancer
GD3 Ganglioside sodium is an Apoptosis inducer and biomarker for mouse neural stem cells. GD3 Ganglioside sodium expresses in neural stem cells and the subventricular zone of the adult mouse brain. GD3 Ganglioside sodium targets the mitochondrial permeability transition pore complex, induces pore opening, dissipates mitochondrial transmembrane potential, triggers Mitochondrial swelling, releases pro-apoptotic factors, and activates Caspase-9. GD3 Ganglioside sodium is applicable to research related to glioblastoma .

HY-157343

GD3 Ganglioside	Apoptosis Mitochondrial Metabolism Caspase	Neurological Disease Cancer
GD3 Ganglioside is an Apoptosis inducer and a biomarker for mouse neural stem cells. GD3 Ganglioside expresses in neural stem cells and the subventricular zone of the adult mouse brain. GD3 Ganglioside targets the mitochondrial permeability transition pore complex, induces pore opening, dissipates mitochondrial transmembrane potential, triggers Mitochondrial swelling, releases pro-apoptotic factors, and activates Caspase-9. GD3 Ganglioside is applicable to research related to glioblastoma .

HY-157343B

GD3 Ganglioside ammonium	Apoptosis Mitochondrial Metabolism Caspase	Neurological Disease Cancer
GD3 Ganglioside ammonium is an Apoptosis inducer and biomarker for mouse neural stem cells. GD3 Ganglioside ammonium expresses in neural stem cells and the subventricular zone of the adult mouse brain. GD3 Ganglioside ammonium targets the mitochondrial permeability transition pore complex, induces pore opening, dissipates mitochondrial transmembrane potential, triggers Mitochondrial swelling, releases pro-apoptotic factors, and activates Caspase-9. GD3 Ganglioside ammonium is applicable to research related to glioblastoma .

HY-167595S

C18:0-d7 GD3 Ceramide (d18:1/18:0-d7)	Isotope-Labeled Compounds	Others
C18:0-d₇ GD3 Ceramide (d₁₈:1/18:0-d₇) is deuterium labeled C18:0 GD3 Ceramide (d18:1/18:0) .

HY-157335

Mn(II)-DO3A sodium	Biochemical Assay Reagents	Others
Mn(II)-DO3A sodium is a Mn(II) complex and a potential alternative to Gd-based MRI contrast agents .

HY-110363

Miglustat-d9 hydrochloride N-Butyldeoxynojirimycin-d9 hydrochloride; NB-DNJ-d9 hydrochloride; OGT 918-d9 hydrochloride	Isotope-Labeled Compounds Glucosylceramide Synthase (GCS)	Neurological Disease
Miglustat-d₉ hydrochloride is the deuterium labeled Miglustat hydrochloride. Miglustat hydrochloride is an inhibitor of glucosylceramide synthase, primarily to treat Type I Gaucher disease (GD1) .

HY-147976A

Glucocerebrosidase-IN-1 hydrochloride	Glycosidase	Neurological Disease
Glucocerebrosidase-IN-1 (compound 11a) hydrochloride is a potent and selective GCase (glucocerebrosidase) inhibitor, with an IC₅₀ of 29.3 μM and a K_i of 18.5 μM. Glucocerebrosidase-IN-1 hydrochloride can be used for the research of Gaucher disease (GD) and Parkinson’s disease (PD) .

HY-131139

Ganglioside GD3 disodium salt	Apoptosis	Neurological Disease Cancer
Ganglioside GD3 disodium salt is an acidic glycosphingolipid. Ganglioside GD3 disodium salt inhibits the proliferation of cancer cells, affects the opening of the mitochondrial permeability transition pore (PTPC), induces apoptosis and activates caspase family. Ganglioside GD3 disodium salt can be used in research about cancer and neurodegenerative diseases .

HY-N16333

C18:0 GD2 Ceramide (d18:1/18:0)	Biochemical Assay Reagents	Others
C18:0 GD2 Ceramide (d18:1/18:0) is a ganglioside .

HY-167596S

C18:0-d7 GD2 Ceramide (d18:1/18:0-d7)	Isotope-Labeled Compounds	Others
C18:0-d₇ GD2 Ceramide (d₁₈:1/18:0-d₇) is deuterium labeled C18:0 GD2 Ceramide (d18:1/18:0) .

HY-162941

SGD-9501-TFA	ADC Linker	Cancer
GD-9501-TFA is an auristatin S-based ADC linker with effective off-target toxicity characteristics, which can be used for the preparation of antibody-drug conjugates (ADCs) .

HY-P10012

Pendetide GYK-DTPA	Biochemical Assay Reagents Radionuclide-Drug Conjugates (RDCs)	Cancer
Pendetide is a chelating agent, can be conjugated with Indium (111In) Capromab for further diagnostic use. Capromab pendetide is a FDA-approved imaging agent for the detection of soft tissue metastases in prostate carcinoma . Pendetide can be used for the synthesis/research of Radionuclide-Drug Conjugates (RDCs).

HY-17020S

Miglustat-d9 N-Butyldeoxynojirimycin-d₉; NB-DNJ-d₉; OGT 918-d₉	Isotope-Labeled Compounds Glucosylceramide Synthase (GCS)	Neurological Disease
Miglustat-d9 is the deuterium labeled Miglustat. Miglustat (N-Butyldeoxynojirimycin) is an inhibitor of glucosylceramide synthase, primarily to treat Type I Gaucher disease (GD1) .

HY-P991668

PF-06688992 Antibody	ADC Antibody	Cancer
PF-06688992 Antibody is an antibody targeting *GD3*. PF-06688992 Antibody can be used for the synthesis of the antibody-drug conjugate PF-06688992 (HY-P991668) .

HY-174252

HSV-1/HSV-2-IN-3	DNA/RNA Synthesis HSV	Infection
HSV-1/HSV-2-IN-3 inhibits the herpes-simplex-virus (HSV) helicase-primase complex, blocking the coordinated DNA-unwinding and primer-synthesis steps required for viral genome replication. HSV-1/HSV-2-IN-3 exhibits an EC₅₀ of 7.0 nM against HSV-2 in a gD-immunofluorescence cell assay containing 2 % FBS and 57.5 nM when 10 % human serum is present. HSV-1/HSV-2-IN-3 achieves an EC₅₀ of 1.1 nM in a qPCR replication assay. HSV-1/HSV-2-IN-3 shows strong selectivity over human carbonic-anhydrase off-targets (IC₅₀ ≈ 2.9 µM for hCA II and > 35 µM for hCA I). HSV-1/HSV-2-IN-3 can be studied in anti-HSV research .

HY-166325A

Ganglioside GD3-d3 ammonium	Biochemical Assay Reagents	Metabolic Disease
Ganglioside GD3-d₃ ammonium is the deuterium labeled Ganglioside GD3 ammonium. Ganglioside GD3 ammonium is an ester product.

HY-166117

N-Hexanoyl-biotin-disialoganglioside GD3	Biochemical Assay Reagents	Metabolic Disease
N-Hexanoyl-biotin-disialoganglioside GD3 is an ester product.

HY-N15811

GD2 Sphingosine (d18:1)	Biochemical Assay Reagents	Others
GD2 Sphingosine (d18:1) is a sphingolipid.

HY-E70049

beta-1,4-N-Acetylgalactosaminyltransferase (CgtA) GM2/GD2 synthase	Others	Neurological Disease
beta-1,4-N-Acetylgalactosaminyltransferase (CgtA) (GM2/GD2 synthase) is a key enzyme which catalyzes the conversion of GM3, GD3 and lactosylceramide (LacCer) to GM2, GD2 and asialo-GM2 (GA2), respectively. beta-1,4-N-Acetylgalactosaminyltransferase (CgtA) is a key enzyme to control the synthesis of brain-enriched complex gangliosides .

HY-167597S

C18:0-d7 GD1b Ceramide (d18:1/18:0-d7)	Isotope-Labeled Compounds	Others
C18:0-d₇ GD1b Ceramide (d₁₈:1/18:0-d₇) is deuterium labeled C18:0 GD1b Ceramide (d18:1/18:0) .

HY-157679

1-O-Hexadecyl-2-eicosapentaenoyl-SN-glycero-3-phosphocholine	Endogenous Metabolite	Cardiovascular Disease
1-O-Hexadecyl-2-eicosapentaenoyl-SN-glycero-3-phosphocholine is a phospholipid present in blood plasma and blood cells .

HY-119987S

Sudan Orange G-d5 SOG-d₅	Isotope-Labeled Compounds	Others
Sudan Orange G-d₅ (SOG-d₅) is the deuterated labeled Sudan Orange G (HY-119987) .

HY-P99743

Mitumomab	Biochemical Assay Reagents	Cancer
Mitumomab is an anti-idiotypic mouse IgG2b monoclonal antibody that mimics the ganglioside *GD3*. Mitumomab can be used for the research of small-cell lung carcinoma .

HY-118634S

trans-Resveratrol-4'-O-D-Glucuronide-d4 R-4G-d₄	Isotope-Labeled Compounds	Others
trans-Resveratrol-4'-O-D-Glucuronide-d₄ (R-4G-d₄) is deuterium labeled trans-Resveratrol-4'-O-D-Glucuronide.

HY-174418

NM600	Biochemical Assay Reagents	Neurological Disease Inflammation/Immunology Cancer
NM600 is an alkylphosphocholine mimetic RPT agent. NM600 demonstrates an antitumor activity against a second GD2+ neuroblastoma xenograft model with SY5Y cells. NM600 can enhance suboptimal CAR T cell efficacy against solid tumors. NM600 can be studied in research for neuroblastoma .

HY-164981

p-SCN-Bn-DOTA(tBu)4	Drug Intermediate	Cancer
p-SCN-Bn-DOTA(tBu)4 is the derivative of DOTA (HY-W053583). p-SCN-Bn-DOTA(tBu)4 is the component of the Gd(III)-DOTA-IAC, which is a targeted magnetic resonance imaging (MRI) contrast agent for αvβ3 integrin receptor .

HY-163332

MPO-IN-6	Glycosidase Dipeptidyl Peptidase Glutathione Peroxidase	Cardiovascular Disease
MPO-IN-6 (compound ADC) is an electrophile with good antioxidant and anti-inflammatory properties. MPO-IN-6 is a myeloperoxidase (MPO), dipeptidyl peptidase-4 (DPP-4), and α-glucosidase (α-GD) inhibitor with IC₅₀s of 10 μM, 31.02 μM, and 46.05 μM, respectively. MPO-IN-6 is a potential cardiovascular preventive agent .

HY-171908

GD3βSph GD3 Sphingosine (d18:1)	Biochemical Assay Reagents	Cancer
GD3βSph (GD3 Sphingosine (d18:1)) is a form of ganglioside GD3 without the fatty acyl group. GD3βSph can be studied in ganglioside cancer research .

Cat. No.	Product Name	Type

HY-158109

M3554	Fluorescent Dyes
M3554 is an anti-GD2 antibody-drug conjugate (ADC) based on the humanized anti-GD2 antibody. M3554 consists of the humanized monoclonal antibody hu14.18 (K322A) (HY-P991040) linked to a topoisomerase 1 inhibitor Exatecan (HY-13631) via a cleavable β-glucuronide linker. M3554 can be used for the study of neuroblastoma, osteosarcoma or glioma .

HY-P991668

PF-06688992 Antibody	Fluorescent Dyes
PF-06688992 Antibody is an antibody targeting *GD3*. PF-06688992 Antibody can be used for the synthesis of the antibody-drug conjugate PF-06688992 (HY-P991668) .

Cat. No.	Product Name	Target	Research Area

HY-P2660

Gly-Asp-Asp-Asp-Asp-Lys-β-naphthylamide GD4K-na	Enteropeptidase	Others
Gly-Asp-Asp-Asp-Asp-Lys-β-naphthylamide (GD4K-na) is a substrate for human enteropeptidase (K_m: 0.16 mM) .

HY-P2022

Pentetreotide	Radionuclide-Drug Conjugates (RDCs)	Cancer
Pentetreotide is a diethylenetriaminopentaacetic (DTPA) conjugate of Octreotide (HY-P0036). Pentetreotide is a somatostatin analog that, when labeled with ¹¹¹In, can be used for nuclear medicine imaging. Somatostatin receptor scintigraphy with Pentetreotide is effective in visualizing neuroendocrine tumors, and its metastasis .

HY-P10012

Pendetide GYK-DTPA	Biochemical Assay Reagents Radionuclide-Drug Conjugates (RDCs)	Cancer
Pendetide is a chelating agent, can be conjugated with Indium (111In) Capromab for further diagnostic use. Capromab pendetide is a FDA-approved imaging agent for the detection of soft tissue metastases in prostate carcinoma . Pendetide can be used for the synthesis/research of Radionuclide-Drug Conjugates (RDCs).

HY-P3413

H-Glu-Pro-Leu-Gln-Leu-Lys-Met-OH	Peptides	Inflammation/Immunology
H-Glu-Pro-Leu-Gln-Leu-Lys-Met-OH (EM7) is a linear mesenchymal stem cells (MSC)-specific peptide. H-Glu-Pro-Leu-Gln-Leu-Lys-Met-OH can be used to prepare Gd-DOTA-peptide complexes .

HY-P3413A

H-Glu-Pro-Leu-Gln-Leu-Lys-Met-OH acetate	Peptides	Others
H-Glu-Pro-Leu-Gln-Leu-Lys-Met-OH (EM7) acetate is a linear mesenchymal stem cell (MSC) specific peptide. H-Glu-Pro-Leu-Gln-Leu-Lys-Met-OH acetate can be used to prepare Gd-DOTA-peptide complexes.

Cat. No.	Product Name	Target	Research Area	Image

HY-P9933

Dinutuximab APN-311; Ch14.18; MAb-14.18	Apoptosis PERK mTOR	Cancer
Dinutuximab (APN-311) is a chimeric human-mouse *anti-GD2* monoclonal antibody. Dinutuximab can bind to *GD2* on the cell surface, triggering antibody-dependent cell-mediated cytotoxicity and complement-dependent cytotoxicity, and promoting tumor regression. Dinutuximab can inhibit the growth, invasion, and migration and induce apoptosis of tumor cells. Dinutuximab can be used in the research of tumors such as neuroblastoma and breast cancer .

HY-P991202

Anti-TSHR Antibody (M22)	TSH Receptor PKA	Metabolic Disease Inflammation/Immunology
Anti-TSHR Antibody (M22) is a selective agonist targeting TSHR (thyroid-stimulating hormone receptor), acting through competitive binding to the extracellular domain of TSHR. Anti-TSHR Antibody (M22) can mimic the biological effects of thyroid-stimulating hormone (TSH), activating downstream cAMP-PKA and other signaling pathways. Anti-TSHR Antibody (M22) can stimulate the proliferation of thyroid follicular epithelial cells and human umbilical vein endothelial cells (HUVECs), promote angiogenesis and tube formation, cell migration, and also upregulate the expression of angiogenesis-related proteins such as PROX1. Anti-TSHR Antibody (M22) can be used in research areas such as the mechanisms of goiter formation in Graves' disease (GD), angiogenesis regulation, and TSHR antagonist screening .

HY-P99206

Naxitamab Naxitamab-gqgk; Humanized 3F8; Hu3F8	Inhibitory Antibodies	Cancer
Naxitamab (Hu3F8) is a humanized monoclonal antibody targeting the disialoganglioside GD2. Naxitamab can be used in research of neuroblastoma, osteosarcoma and other GD2-positive cancers .

HY-P990845

Anti-Ganglioside GD2 Antibody (14G2a)	Inhibitory Antibodies	Cancer
Anti-Ganglioside GD2 Antibody (14G2a) is a kind of mouse IgG2a κ chimeric antibody inhibitor, targeting to human Ganglioside GD2. Anti-Ganglioside GD2 Antibody (14G2a) can induce neuroblastoma cells autophagy and lysis. Anti-Ganglioside GD2 Antibody (14G2a) can be used for the research of cancer, such as neuroblastoma .

HY-P99757

Nivatrotamab Hu3F8-BSAb	CD2 CD3	Cancer
Nivatrotamab (Hu3F8-BsAb) is a humanized anti-GD2/CD3 bispecific antibody. Nivatrotamab is a CD3- and GD2-specific bsAb-based T-cell engager. Nivatrotamab can be used in research of neuroblastoma .

HY-P991040

hu14.18 (K322A) Gamsitabart; M3554 Antibody	Inhibitory Antibodies	Cancer
hu14.18 (K322A) is a humanized anti-disialoganglioside GD2 monoclonal antibody that contains fully human amino acid sequences for immunoglobulin G1 heavy and kappa light chains. hu14.18 (K322A) has antibody-dependent cellular cytotoxicity (ADCC). hu14.18 (K322A) can be used for the study of high-risk neuroblastoma .

HY-P99873

Ecromeximab KM 871; KW 2871	Inhibitory Antibodies	Others
Ecromeximab (KM 871; KW 2871) is a mouse-derived IgG-κ chimeric antibody targeting ganglioside GD3. Ecromeximab is expressed by YB2/0 rat hybridoma cells .

HY-P99206A

Naxitamab (Mouse IgG1)	Inhibitory Antibodies	Cancer
Naxitamab (Hu3F8) (Mouse IgG1) is a mouse-derived IgG1 monoclonal antibody targeting the diazoglycoside GD2 (hu3F8). Naxitamab can be used in the research of neuroblastoma, osteosarcoma, and other GD2-positive cancers .

HY-P991668

PF-06688992 Antibody	ADC Antibody	Cancer
PF-06688992 Antibody is an antibody targeting *GD3*. PF-06688992 Antibody can be used for the synthesis of the antibody-drug conjugate PF-06688992 (HY-P991668) .

HY-P991585

MORAb-028	Inhibitory Antibodies	Cancer
MORAb-028 is a humanized IgG1 monoclonal antibody inhibitor targeting *GD2*. MORAb-028 has a potent antitumor activity and kills GD2-expressing target cells via complement-mediated cytotoxicity (CDC). MORAb-028 significantly inhibits tumor growth in EL-4-luc xenograft mice model. MORAb-028 can be used for melanoma cancer research .

HY-P99743

Mitumomab	Biochemical Assay Reagents	Cancer
Mitumomab is an anti-idiotypic mouse IgG2b monoclonal antibody that mimics the ganglioside *GD3*. Mitumomab can be used for the research of small-cell lung carcinoma .

HY-P991131

Daretabart	Inhibitory Antibodies	Cancer
Daretabart is a humanized IgG1K antibody targeting *GD2*, which can be used for anti-tumor research. The corresponding isotype control is: Human lgG1 kappa, lsotype Control (HY-P99001) .

HY-P990076

Lorukafusp alfa APN-301; hu14.18-IL2; EMD 273063	Inhibitory Antibodies	Cancer
Lorukafusp alfa (14.18 mAb; hu14.18-IL2) is an immunocytokine consisting of the humanized 14.18 anti-GD2 mAb linked to IL210. Lorukafusp alfa has activity mediated by activation of antibody-dependent cellular cytotoxicity (ADCC) and complement-dependent cytotoxicity via the binding of hu14.18-IL2 to GD2 on the tumor cell surface, followed by binding to Fc receptors on effector cells along with activation of NK and T cells via IL2 receptor binding. Lorukafusp alfa has anti-tumor activity .

HY-P992317

ATL301	Inhibitory Antibodies	Inflammation/Immunology Cancer
ATL301 is a human monoclonal antibody that targets human ganglioside GD2 (ganglioside GD2). GD2 is a highly expressed glycolipid antigen on the surface of neuroepithelial tumor cells, and is commonly found in neuroblastoma, melanoma, osteosarcoma, small cell lung cancer, etc.

HY-P990916

Donitabart	Inhibitory Antibodies	Inflammation/Immunology
HY-P990916 is an ganglioside GD2-targeting IgG1κ type chimeric humanized antibody, the recommed isotype control is Human IgG1 kappa, Isotype Control (HY-P99001) .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N16333

C18:0 GD2 Ceramide (d18:1/18:0)	Lipid	Biochemical Assay Reagents
C18:0 GD2 Ceramide (d18:1/18:0) is a ganglioside .

HY-N15811

GD2 Sphingosine (d18:1)	Lipid	Biochemical Assay Reagents
GD2 Sphingosine (d18:1) is a sphingolipid.

HY-N15776

C24:1 GD2 Ceramide (d18:1/24:1)	Lipid	Biochemical Assay Reagents
C24:1 GD2 Ceramide (d18:1/24:1) is a sphingoid base linked to a fatty acid. C24:1 GD2 Ceramide (d18:1/24:1) interacts with other membrane lipids and allows GD2 to be tightly anchored to the cell surface .

Species:	Human (4) Virus (5)
Tag:	His (8) Myc (1) gD (1)
Source:	HEK293 (7) E. coli Cell-free (1) Sf9 insect cells (1)

Cat. No.	Compare	Product Name	Species	Source	Image

HY-P703871

	glycoprotein D/gD Protein, HSV-2 (HEK293, His) Envelope glycoprotein D; Gd; US6	Virus	HEK293
	glycoprotein D/gD Protein, HSV-2 (HEK293, His) is the recombinant virus-derived glycoprotein D/gD protein, expressed by HEK293, with C-His tag.

HY-P78670

	IgG1 Protein, Human (HEK293, gD) IgG1	Human	HEK293
	The IgG1 protein is the constant region of the immunoglobulin heavy chain and serves as a receptor during the recognition phase of humoral immunity. It triggers clonal expansion and differentiation of B lymphocytes into immunoglobulin-secreting plasma cells. IgG1 Protein, Human (HEK293, gD) is the recombinant human-derived IgG1 protein, expressed by HEK293 , with C-gD labeled tag.

HY-P702292

	glycoprotein D/gD Protein, HHV-2 (Cell-Free, His) Envelope glycoprotein D	Virus	E. coli Cell-free
	Glycoprotein D/gD proteins bind to host cell receptors TNFRSF14/HVEM and NECTIN1, triggering fusion with the host membrane by recruiting gB and gH/gL. glycoprotein D/gD Protein, HHV-2 (Cell-Free, His) is the recombinant Virus-derived glycoprotein D/gD protein, expressed by E. coli Cell-free , with N-10*His labeled tag.

HY-P704068

	glycoprotein D/gD Protein, HSV-1 (HEK293, His) Envelope Glycoprotein D,Human alphaherpesvirus 1,HSV-1	Virus	HEK293
	glycoprotein D/gD Protein, HSV-1 (HEK293, His) is the recombinant virus-derived glycoprotein D/gD protein, expressed by HEK293, with C-6*His tag.

HY-P700004

	PAEP Protein, Human (HEK293, His) Alpha uterine protein; gD; GdA; GdF; GdS; Glycodelin A; Glycodelin; Glycodelin F; Glycodelin S; MGC138509; MGC142288; PAEG	Human	HEK293
	PAEP protein is a glycoprotein that regulates fertilization steps and exhibits immunomodulatory effects. PAEP Protein, Human (HEK293, His) is the recombinant human-derived PAEP protein, expressed by HEK293 , with N-10*His labeled tag.

HY-P71669

	PAEP Protein, Human (HEK293, Myc, His) Alpha uterine protein; gD; GdA; GdF; GdS; Glycodelin A; Glycodelin; Glycodelin F; Glycodelin S; MGC138509; MGC142288; PAEG	Human	HEK293
	PAEP protein is a glycoprotein that regulates fertilization steps and exhibits immunomodulatory effects. PAEP Protein, Human (HEK293, Myc, His) is the recombinant human-derived PAEP protein, expressed by HEK293 , with C-Myc, N-10*His labeled tag.

HY-P74942

	HA1/Hemagglutinin Protein, H5N6 (AIA24403, HEK293, His) Influenza A H5N6 (A/duck/Guangdong/GD01/2014) Hemagglutinin / HA1 Protein (His)	Virus	HEK293
	The hemagglutinin HA1 protein is essential for attachment of virions to host cells by binding to sialic acid-containing receptors, inducing virion internalization via clathrin-dependent or clathrin- and caveolin-independent pathways.As a class I viral fusion protein, HA1 determines host range restriction and virulence, mediating fusion between the virion membrane and the endosomal membrane.HA1/Hemagglutinin Protein, H5N6 (AIA24403, HEK293, His) is the recombinant Virus-derived HA1/Hemagglutinin protein, expressed by HEK293 , with C-His labeled tag.

HY-P75028

	HA/Hemagglutinin Protein, H5N6 (AIA24403, sf9, His) Influenza A H5N6 (A/duck/Guangdong/GD01/2014) Hemagglutinin / HA Protein (sf9, His)	Virus	Sf9 insect cells
	The hemagglutinin HA1 protein is essential for attachment of virions to host cells by binding to sialic acid-containing receptors, inducing virion internalization via clathrin-dependent or clathrin- and caveolin-independent pathways.As a class I viral fusion protein, HA1 determines host range restriction and virulence, mediating fusion between the virion membrane and the endosomal membrane.HA/Hemagglutinin Protein, H5N6 (AIA24403, sf9, His) is the recombinant Virus-derived HA/Hemagglutinin protein, expressed by Sf9 insect cells , with C-His labeled tag.

HY-P71334

	ST8SIA1 Protein, Human (HEK293, His) Alpha-N-Acetylneuraminide Alpha-2; 8-Sialyltransferase; Alpha-2; 8-Sialyltransferase 8A; Ganglioside GD3 Synthase; Ganglioside GT3 Synthase; Sialyltransferase 8A; SIAT8-A; Sialytransferase St8Sia I; ST8SiaI; ST8SIA1; SIAT8; SIAT8A	Human	HEK293
	The ST8SIA1 protein links sialic acid to ganglioside GM3 via an α 2,8-bond to form ganglioside GD3. ST8SIA1 Protein, Human (HEK293, His) is the recombinant human-derived ST8SIA1 protein, expressed by HEK293 , with C-6*His labeled tag.

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Species
Source
Tag
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Free Sample	Yes No
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Cat. No.	Product Name	Chemical Structure

HY-17591S

Penicillin G-d5 potassium
Penicillin G-d₅ (potassium) is the deuterium labeled Penicillin G potassium. Penicillin G potassium is a fast-acting antibiotic; used to treat bacterial infections that affect the blood, heart, lungs, joints, and genital areas .

HY-N7139S1

Penicillin G-d7 potassium salt
Penicillin G-d₇ (potassium) is the deuterium labeled Penicillin G potassium salt .

HY-167595S

C18:0-d7 GD3 Ceramide (d18:1/18:0-d7)
C18:0-d₇ GD3 Ceramide (d₁₈:1/18:0-d₇) is deuterium labeled C18:0 GD3 Ceramide (d18:1/18:0) .

HY-110363

Miglustat-d9 hydrochloride
Miglustat-d₉ hydrochloride is the deuterium labeled Miglustat hydrochloride. Miglustat hydrochloride is an inhibitor of glucosylceramide synthase, primarily to treat Type I Gaucher disease (GD1) .

HY-167596S

C18:0-d7 GD2 Ceramide (d18:1/18:0-d7)
C18:0-d₇ GD2 Ceramide (d₁₈:1/18:0-d₇) is deuterium labeled C18:0 GD2 Ceramide (d18:1/18:0) .

HY-17020S

Miglustat-d9
Miglustat-d9 is the deuterium labeled Miglustat. Miglustat (N-Butyldeoxynojirimycin) is an inhibitor of glucosylceramide synthase, primarily to treat Type I Gaucher disease (GD1) .

HY-166325A

Ganglioside GD3-d3 ammonium
Ganglioside GD3-d₃ ammonium is the deuterium labeled Ganglioside GD3 ammonium. Ganglioside GD3 ammonium is an ester product.

HY-167597S

C18:0-d7 GD1b Ceramide (d18:1/18:0-d7)
C18:0-d₇ GD1b Ceramide (d₁₈:1/18:0-d₇) is deuterium labeled C18:0 GD1b Ceramide (d18:1/18:0) .

HY-119987S

Sudan Orange G-d5
Sudan Orange G-d₅ (SOG-d₅) is the deuterated labeled Sudan Orange G (HY-119987) .

HY-118634S

trans-Resveratrol-4'-O-D-Glucuronide-d4
trans-Resveratrol-4'-O-D-Glucuronide-d₄ (R-4G-d₄) is deuterium labeled trans-Resveratrol-4'-O-D-Glucuronide.

HY-166891S

Tiotropium EP Impurity G-d3Iodide
Tiotropium EP Impurity G-d₃(Iodide) is deuterium labeled Tiotropium EP Impurity G .

HY-D0303AS

Chrysoidine G-d5 hydrochloride

Chrysoidine G-d₅ hydrochloride (Solvent Orange 3-d₅ hydrochloride) is the deuterium labeled Chrysoidine G (HY-D0303A). Chrysoidine G (Solvent Orange 3 hydrochloride) is an industrial azoic dye (cationic dye). Chrysoidine G (Solvent Orange 3 hydrochloride) is used for the construction of most textile dyestuffs and also in synthetic industrial compounds. Chrysoidine G (Solvent Orange 3 hydrochloride) concentration can be determined by UV-Vis spectroscopy .

HY-W724290

Tetrabutylammonium-d36 bromide

Tetrabutylammonium-d₃₆ bromide (AP 6G-d₃₆ bromide) is the deuterium labeled Tetrabutylammonium bromide (HY-D0172). Tetrabutylammonium bromide is an organic ammonium compound, which is often used in catalytic reactions and separation and purification processes. It has a significant catalytic effect in some organic synthesis reactions, and can be used as a surfactant, stabilizer and antibacterial agent, etc. In addition, in some laboratory studies, this compound has also been used as an ion exchanger, solvent extractant, etc.

Host:	Mouse (2) Rabbit (2)
Reactivity:	Human (4) Rat (2) Mouse (2)
Application:	ICC/IF (4) WB (2) FC (2)
Isotype:	IgG (2) IgG1 (2)
Conjugation:	Non-conjugated (4)
Clonality:	Monoclonal (2) Recombinant (1)
Modification:	Unmodified (2)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P88843

	MIF4GD Antibody (YA8527) AD023; MIFD; SLIP1	ICC/IF, FC	Human, Mouse, Rat
	MIF4GD Antibody (YA8527) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to MIF4GD.

HY-P88843A

	MIF4GD Antibody (YA8527)(PBS only) AD023; MIFD; SLIP1	ICC/IF, FC	Human, Mouse, Rat
	MIF4GD Antibody (YA8527) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to MIF4GD.

HY-P83540

	TPX2 Antibody (YA3285) DIL2; p100; DIL-2; HCTP4; FLS353; HCA519; REPP86; C20orf1; C20orf2; GD:C20orf1	WB, ICC/IF	Human
	TPX2 Antibody (YA3285) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to TPX2.

HY-P83540A

	TPX2 Antibody (YA3285)(PBS only) DIL2; p100; DIL-2; HCTP4; FLS353; HCA519; REPP86; C20orf1; C20orf2; GD:C20orf1	WB, ICC/IF	Human
	TPX2 Antibody (YA3285) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to TPX2.

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Application
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Appearance
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SwissProt ID
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Free Sample	Yes No
Size	* This product has been "discontinued". Optimized version of product available: / In-stock - + Add to Cart Get quote

Cat. No.	Product Name		Classification

HY-172699

DSPE-PEG2000-ANG		Pegylated Lipids
DSPE-PEG2000-ANG is a conjugate of DSPE-PEG2000-MAL and Angiopep-2. Angiopep-2 is a peptide ligand that targets LRP-1. DSPE-PEG2000-ANG is used to synthesize gadolinium-boron bifunctionalized lipid nanoparticles BPA-F&DOTA-Gd@LIPO-ANG with blood-brain barrier and glioma targeting properties .

HY-157679

1-O-Hexadecyl-2-eicosapentaenoyl-SN-glycero-3-phosphocholine		Phospholipids
1-O-Hexadecyl-2-eicosapentaenoyl-SN-glycero-3-phosphocholine is a phospholipid present in blood plasma and blood cells .

HY-174517

Human TNFRSF14 mRNA		mRNA
Human TNFRSF14 mRNA encodes the human TNF receptor superfamily member 14 (TNFRSF14) protein, a member of the TNF receptor superfamily. TNFRSF14 functions in signal transduction pathways that activate inflammatory and inhibitory T-cell immune response. It binds herpes simplex virus (HSV) viral envelope glycoprotein D (gD), mediating its entry into cells.

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