Glucocerebrosidase-IN-1 hydrochloride
Based on 1 Customer Validation
Glucocerebrosidase-IN-1 (compound 11a) hydrochloride is a potent and selective GCase (glucocerebrosidase) inhibitor, with an IC50 of 29.3 μM and a Ki of 18.5 μM. Glucocerebrosidase-IN-1 hydrochloride can be used for the research of Gaucher disease (GD) and Parkinson’s disease (PD).
For research use only. We do not sell to patients.
- Purity : 99.16%
- CAS No.: 2279945-77-4
- Formula: C13H28ClNO3
- Molecular Weight:281.82
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
Chemical Information
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CAS No. 2279945-77-4
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Appearance Solid
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Molecular Weight 281.82
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Formula C13H28ClNO3
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Color White to off-white
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SMILES
O[C@@H]1[C@@H](CCCCCCCC)NC[C@@H](O)[C@H]1O.[H]Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
In Vitro:
DMSO : 12.5 mg/mL (44.35 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (268 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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| DMSO | 1 mM | 3.5484 mL | 17.7418 mL | 35.4836 mL | 88.7091 mL |
| 5 mM | 0.7097 mL | 3.5484 mL | 7.0967 mL | 17.7418 mL | |
| 10 mM | 0.3548 mL | 1.7742 mL | 3.5484 mL | 8.8709 mL | |
| 15 mM | 0.2366 mL | 1.1828 mL | 2.3656 mL | 5.9139 mL | |
| 20 mM | 0.1774 mL | 0.8871 mL | 1.7742 mL | 4.4355 mL | |
| 25 mM | 0.1419 mL | 0.7097 mL | 1.4193 mL | 3.5484 mL | |
| 30 mM | 0.1183 mL | 0.5914 mL | 1.1828 mL | 2.9570 mL | |
| 40 mM | 0.0887 mL | 0.4435 mL | 0.8871 mL | 2.2177 mL |
Glucocerebrosidase-IN-1 hydrochloride Related Classifications
HY-147976A Related Classifications
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