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Pentetreotide 

Cat. No.: HY-P2022
Handling Instructions

Pentetreotide is a diethylenetriaminopentaacetic (DTPA) conjugate of Octreotide. Pentetreotide is an indium-labelled somatostatin analog and can be uesd to nuclear medicine imaging. Somatostatin receptor scintigraphy with Pentetreotide is effective in visualizing neuroendocrine tumors, and its metastasis.

For research use only. We do not sell to patients.

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Pentetreotide Chemical Structure

Pentetreotide Chemical Structure

CAS No. : 138661-02-6

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Description

Pentetreotide is a diethylenetriaminopentaacetic (DTPA) conjugate of Octreotide. Pentetreotide is an indium-labelled somatostatin analog and can be uesd to nuclear medicine imaging. Somatostatin receptor scintigraphy with Pentetreotide is effective in visualizing neuroendocrine tumors, and its metastasis[1][2].

In Vitro

Neuroendocrine tumors have an increased number of somatostatin receptors, as compared to normal tissues. At present time, there are five known subtypes. Somatostatin receptor scintigraphy with 111In-Pentetreotide binds to two of these subtypes and is effective in visualizing neuroendocrine tumors, and its metastasis with an overall diagnostic sensitivity of 70% to 90%. It is considerably more sensitive than conventional anatomic imaging. Its usage in neuroendocrine tumors not only includes assessment of disease extent, but also in identified primary lesion, assesses treatment response, and selection for radionuclide therapy[1].

Molecular Weight

1394.57

Formula

C₆₃H₈₇N₁₃O₁₉S₂

CAS No.

138661-02-6

Sequence

Gly-Phe-Cys-Phe-Trp-Lys-Thr-Cys-Thr (Disulfide bridge: Cys3-Cys8)

Sequence Shortening

G{D-Phe}CF{D-Trp}KTCT (Disulfide bridge: Cys3-Cys8)

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

PentetreotideOthersDTPAindium-labelledtumurtracerscintigraphysomatostatinmetastasisSPECTCTInhibitorinhibitorinhibit

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