Ganglioside GD1b Disodium Salt (Bovine Brain)
Based on 1 Customer Validation
Ganglioside GD1b Disodium Salt (Bovine Brain) (Disialoganglioside GD1b; Ganglioside C1) is an acidic glycosphingolipid containing two sialic acid residues linked to an internal galactose unit. Ganglioside GD1b Disodium Salt tightly packs with cholesterol to form lipid microdomains that modulate intracellular and intercellular signaling events. Concentrations of Ganglioside GD1b Disodium Salt (Bovine Brain) in the human brain increase with age and are positively correlated with pilocytic astrocytoma tumor grade. Ganglioside GD1b Disodium Salt has been detected in various other gliomas, including primitive neuroectodermal tumors, glioblastomas, and anaplastic astrocytomas.
For research use only. We do not sell to patients.
- Purity : 98%
- CAS No.: 19553-76-5
- Formula: C₈₄H₁₄₆N₄Na₂O₃₉
- Molecular Weight:1882.04
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
All Endogenous Metabolite Isoforms
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Biological Activity
Description
Chemical Information
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CAS No. 19553-76-5
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Appearance Solid
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Molecular Weight 1882.04
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Formula C₈₄H₁₄₆N₄Na₂O₃₉
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Color White to off-white
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SMILES
O[C@H]1[C@@H](O)[C@@H](CO)O[C@@H](O[C@H]2[C@@H](O)[C@@H](CO)O[C@@H](O[C@@H]3[C@H](O[C@]4(C(O[Na])=O)C[C@H](O)[C@@H](NC(C)=O)[C@H]([C@H](O)[C@H](O[C@]5(C(O[Na])=O)C[C@H](O)[C@@H](NC(C)=O)[C@H]([C@H](O)[C@H](O)CO)O5)CO)O4)[C@@H](O)[C@H](O[C@H]6[C@H](O)[C@@H](O)[C@H](OCC(NC(CCCCCCCCCCCCCCCCC)=O)C(O)/C=C/CCCCCCCCCCCCC)O[C@@H]6CO)O[C@@H]3CO)[C@@H]2NC(C)=O)[C@@H]1O
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Synonyms
Disialoganglioside GD1b; Ganglioside C1; Ganglioside G2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
In Vitro:
DMSO : ≥ 50 mg/mL (26.57 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (274 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 0.5313 mL | 2.6567 mL | 5.3134 mL | 13.2835 mL |
| 5 mM | 0.1063 mL | 0.5313 mL | 1.0627 mL | 2.6567 mL | |
| 10 mM | 0.0531 mL | 0.2657 mL | 0.5313 mL | 1.3283 mL | |
| 15 mM | 0.0354 mL | 0.1771 mL | 0.3542 mL | 0.8856 mL | |
| 20 mM | 0.0266 mL | 0.1328 mL | 0.2657 mL | 0.6642 mL | |
| 25 mM | 0.0213 mL | 0.1063 mL | 0.2125 mL | 0.5313 mL |