Search Result

Isoforms Recommended:	FGFR2

Results for "

FGF-R2

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Apoptosis (8) Aurora Kinase (2) c-Fms (1) CDK (1) Cytochrome P450 (1) Drug Metabolite (1) Drug-Linker Conjugates for ADC (1) EGFR (2) Endogenous Metabolite (3) FGFR (48) FLT3 (3) GSK-3 (1) HDAC (1) Isotope-Labeled Compounds (1) JAK (1) PDGFR (6) PROTACs (1) Reactive Oxygen Species (1) Small Interfering RNA (siRNA) (3) Src (6) VEGFR (9)
By Research Areas:	Cancer (48) Cardiovascular Disease (3) Inflammation/Immunology (1)

Inhibitors & Agonists

Inhibitory Antibodies

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-145230

FGFR2-IN-1

FGFR Others

FGFR2-IN-1 is a selective FGFR2 inhibitor with an IC₅₀ of 140 nM.
HY-145231

FGFR2-IN-2

FGFR Cancer

FGFR2-IN-2 (Compound 38) is a selective FGFR2 inhibitor with IC₅₀s of 389, 29, and 758 nM for FGFR1, FGFR2, and FGFR3, respectively .

FGFR2-IN-1	FGFR	Others
FGFR2-IN-1 is a selective *FGFR2* inhibitor with an IC₅₀ of 140 nM.

FGFR2-IN-2	FGFR	Cancer
FGFR2-IN-2 (Compound 38) is a selective *FGFR2* inhibitor with IC₅₀s of 389, 29, and 758 nM for FGFR1, FGFR2, and FGFR3, respectively .

HY-RS04915

FGFR2 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
FGFR2 Human Pre-designed siRNA Set A contains three designed siRNAs for FGFR2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

FGFR2 Human Pre-designed siRNA Set A FGFR2 Human Pre-designed siRNA Set A

HY-RS04916

Fgfr2 Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Fgfr2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Fgfr2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Fgfr2 Mouse Pre-designed siRNA Set A Fgfr2 Mouse Pre-designed siRNA Set A

HY-RS04917

Fgfr2 Rat Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Fgfr2 Rat Pre-designed siRNA Set A contains three designed siRNAs for Fgfr2 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

Fgfr2 Rat Pre-designed siRNA Set A Fgfr2 Rat Pre-designed siRNA Set A

HY-151903S

FGFR2/3-IN-1	FGFR	Cancer
FGFR2/3-IN-1 is a potent and selective FGFR2 and FGFR3 (FGFR) inhibitor with IC50s of 1 nM and 0.5 nM, respectively. FGFR2/3-IN-1 displays >40-fold selectivity over FGFR1/FGFR4 and other kinome. FGFR2/3-IN-1 also inhibits FGFR3 V555L and V555M mutants with IC50s of 2.7 nM and 6.1 nM, respectively[1].

HY-141685

3-Methylthienyl-carbonyl-JNJ-7706621	CDK GSK-3 VEGFR FGFR	Cancer
3-Methylthienyl-carbonyl-JNJ-7706621 is a potent and selective inhibitor of cyclin-dependent kinase (CDK), with IC₅₀s of 6.4 nM and 2 nM for CDK1/cyclin B and CDK2/cyclin A, respectively. 3-Methylthienyl-carbonyl-JNJ-7706621 also shows potent inhibition of GSK-3 (IC₅₀=0.041 μM) and modest potency against CDK4, *VEGF-R2, and FGF-R2* (IC₅₀=0.11, 0.13, 0.22 μM, respectively). 3-Methylthienyl-carbonyl-JNJ-7706621 can be used for the research of cancer .

HY-P99007

Aprutumab BAY 1179470	FGFR	Cancer
Aprutumab (BAY 1179470) is a fully human *FGFR2* monoclonal antibody, which binds to the FGFR2 isoforms FGFR2-IIIb and FGFR2-IIIc. Aprutumab has the potential for solid tumors research .

HY-149843

LC-MB12	FGFR PROTACs	Cancer
LC-MB12 is an orally active PROTAC compound targets *FGFR2* degradation with a DC₅₀ of 11.8 nM. LC-MB12 contains BGJ398 (a FGFR2 inhibitor), PROTAC linker and CRBN.LC-MB12 inhibits *FGFR2* signaling in gastric cancer cells and has anti-tumor activity .

HY-147250A

Lirafugratinib hydrochloride RLY-4008 hydrochloride	FGFR	Cancer
Lirafugratinib (RLY-4008) hydrochloride is an orally active, irreversible and highly selective *FGFR2* inhibitor with an IC₅₀ of 3 nM. Lirafugratinib hydrochloride covalently binds to Cys491. Lirafugratinib hydrochloride targets FGFR2 primary alterations and resistance mutations and induces tumor regression while sparing other FGFRs .

HY-147250

Lirafugratinib RLY-4008	FGFR	Cancer
Lirafugratinib (RLY-4008) is an orally active, irreversible and highly selective *FGFR2* inhibitor with an IC₅₀ of 3 nM. Lirafugratinib covalently binds to Cys491. Lirafugratinib targets FGFR2 primary alterations and resistance mutations and induces tumor regression while sparing other FGFRs .

HY-N0183

Formononetin 5+ Cited Publications Biochanin B; Flavosil; Formononetol	FGFR Apoptosis	Cardiovascular Disease Cancer
Formononetin is a potent *FGFR2* inhibitor with an IC₅₀ of ~4.31 μM. Formononetin potently inhibits angiogenesis and tumor growth .

HY-17601

Alofanib 3 Publications Verification RPT835	FGFR Apoptosis	Cardiovascular Disease Cancer
Alofanib (RPT835) is a potent and selective allosteric inhibitor of fibroblast growth factor receptor 2 (FGFR2). Anticancer and antiangiogenic activity ^[2].

HY-18602

FIIN-2

FGFR Cancer

FIIN-2 is an irreversible inhibitor of FGFR with an IC₅₀ of 3.1, 4.3, 27, and 45 nM for FGFR1, FGFR2, FGFR3 and FGFR4, respectively.
HY-145043

FGFR-IN-1

FGFR Cancer

FGFR-IN-1 is a potent FGFR inhibitor with an IC₅₀ of <100 nM for FGFR1, FGFR2, and FGFR3, respectively (patent US20130338134A1, example 219) .

FIIN-2	FGFR	Cancer
FIIN-2 is an irreversible inhibitor of *FGFR* with an IC₅₀ of 3.1, 4.3, 27, and 45 nM for FGFR1, FGFR2, FGFR3 and FGFR4, respectively.

FGFR-IN-1	FGFR	Cancer
FGFR-IN-1 is a potent *FGFR* inhibitor with an IC₅₀ of <100 nM for FGFR1, FGFR2, and FGFR3, respectively (patent US20130338134A1, example 219) .

HY-N0060A

Ferulic acid sodium 5 Publications Verification Coniferic acid sodium	FGFR Endogenous Metabolite Reactive Oxygen Species	Cardiovascular Disease Cancer
Ferulic acid sodium is a novel fibroblast growth factor receptor 1 (FGFR1) inhibitor with IC₅₀s of 3.78 and 12.5 μM for *FGFR1* and *FGFR2*, respectively.

HY-18603

FIIN-3

EGFR FGFR Cancer

FIIN-3 is an irreversible inhibitor of FGFR with an IC₅₀ of 13.1, 21, 31.4, and 35.3 nM for FGFR1, FGFR2, FGFR3 and FGFR4, respectively.

FIIN-3	EGFR FGFR	Cancer
FIIN-3 is an irreversible inhibitor of *FGFR* with an IC₅₀ of 13.1, 21, 31.4, and 35.3 nM for FGFR1, FGFR2, FGFR3 and FGFR4, respectively.

HY-N0060

Ferulic acid 5 Publications Verification Coniferic acid	FGFR Endogenous Metabolite	Cancer
Ferulic acid is a novel fibroblast growth factor receptor 1 (FGFR1) inhibitor with IC₅₀s of 3.78 and 12.5 μM for *FGFR1* and *FGFR2*, respectively.

HY-101544

ARQ 069	FGFR	Cancer
ARQ 069, an analog of ARQ 523, inhibits *FGFR* in an enantiospecific manner. ARQ 069 targets the unphosphorylated, inactive forms of FGFR1/FGFR2 kinases (IC₅₀s of 0.84 μM and 1.23 μM, respectively). ARQ 069 inhibits FGFR1/FGFR2 autophosphorylation (IC₅₀s of 2.8 and 1.9 μM, respectively) through a mechanism in a non-ATP competitive dependent manner .

HY-13304

LY2874455

3 Publications Verification

FGFR Cancer

LY2874455 is a pan-FGFR inhibitor with IC₅₀s of 2.8, 2.6, 6.4, 6 nM for FGFR1, FGFR2, FGFR3, FGFR4, respectively.

LY2874455 3 Publications Verification	FGFR	Cancer
LY2874455 is a *pan-FGFR* inhibitor with IC₅₀s of 2.8, 2.6, 6.4, 6 nM for *FGFR1, FGFR2, FGFR3, FGFR4*, respectively.

HY-19957

Zoligratinib 2 Publications Verification Debio 1347; CH5183284	FGFR	Cancer
Zoligratinib (Debio 1347) is an orally available and selective *FGFR* inhibitor with IC₅₀s of 9.3, 7.6, and 22 nM for FGFR1, FGFR2, FGFR3, and FGFR4, respectively.

HY-100818

Futibatinib 2 Publications Verification TAS-120	FGFR	Cancer
Futibatinib (TAS-120) is an orally bioavailable, highly selective, and irreversible *FGFR* inhibitor, with IC₅₀s of 3.9, 1.3, 1.6, and 8.3 nM for FGFR 1-4, respectively. Futibatinib inhibits mutant and wild-type FGFR2 with similar IC₅₀s (wild-type FGFR2=0.9 nM; V5651=1-3 nM; N550H=3.6 nM; E566G=2.4 nM) ^[2] .

HY-13330

Fexagratinib 15+ Cited Publications AZD4547; ADSK091	FGFR	Cancer
Fexagratinib (AZD4547; ADSK091) is a potent inhibitor of the *FGFR* family with IC₅₀s of 0.2 nM, 2.5 nM, 1.8 nM, and 165 nM for *FGFR1, FGFR2, FGFR3, and FGFR4*, respectively.

HY-13311A

Infigratinib phosphate Maximum Cited Publications 25 Publications Verification BGJ-398 phosphate; NVP-BGJ398 phosphate	FGFR	Cancer
Infigratinib phosphate (BGJ-398 phosphate; NVP-BGJ398 phosphate) is a potent inhibitor of the *FGFR* family with IC₅₀ of 0.9 nM, 1.4 nM, 1 nM, and 60 nM for *FGFR1, FGFR2, FGFR3, and FGFR4*, respectively.

HY-13034

Gandotinib 3 Publications Verification LY2784544	JAK FLT3 FGFR VEGFR	Cancer
Gandotinib (LY2784544) is a potent *JAK2* inhibitor with IC₅₀ of 3 nM. Gandotinib (LY2784544) also inhibits FLT3, FLT4, FGFR2, TYK2, and TRKB with IC₅₀ of 4, 25, 32, 44, and 95 nM.

HY-13311

Infigratinib Maximum Cited Publications 25 Publications Verification BGJ-398; NVP-BGJ398	FGFR Apoptosis	Cancer
Infigratinib (BGJ-398; NVP-BGJ398) is a potent inhibitor of the *FGFR* family with IC₅₀s of 0.9 nM, 1.4 nM, 1 nM, and 60 nM for *FGFR1, FGFR2, FGFR3, and FGFR4*, respectively.

HY-13311S

Infigratinib-d3 BGJ-398-d₃; NVP-BGJ398-d₃	FGFR	Cancer
Infigratinib-d3 is a deuterated analog of infigratinib. Infigratinib is an effective inhibitor of the *FGFR* family, with IC₅₀ values of 0.9 nM, 1.4 nM, 1 nM, and 60 nM for *FGFR1, FGFR2, FGFR3, and FGFR4*, respectively .

HY-150652

FGFR-IN-8	FGFR Apoptosis	Cancer
FGFR-IN-8 (Compound 17a) is a highly potent and orally active panFGFR inhibitor against wild-type and mutant FGFRs. FGFR-IN-8 shows inhibition with IC₅₀ values of <0.5, 189.1, <0.5, 22.6, <0.5 and 7.30 nM against FGFR1, V564F-FGFR2, N549H-FGFR2, V555M-FGFR3, FGFR3 and FGFR4, respectively. GFR-IN-8 induces cancer cell apoptosis and shows anticancer activities .

HY-N0060S1

Ferulic acid-13C3	Isotope-Labeled Compounds FGFR Endogenous Metabolite	Cancer
Ferulic acid- ¹³C₃ is the ¹³C-labeled Ferulic acid. Ferulic acid is a novel fibroblast growth factor receptor 1 (FGFR1) inhibitor with IC50s of 3.78 and 12.5 μM for FGFR1 and FGFR2, respectively.

HY-148779

FGFR3-IN-5	FGFR	Cancer
FGFR3-IN-5 is a potent and selective *FGFR3* inhibitor with IC₅₀ values of 3, 44, and 289 nM for FGFR3, FGFR2, and FGFR1, respectively. FGFR3-IN-5 can be used in research of cancer .

HY-15391

Lucitanib 5+ Cited Publications E-3810	VEGFR FGFR	Cancer
Lucitanib (E-3810) is a novel dual inhibitor of VEGFR and *FGFR, potently and selectively inhibits VEGFR1, VEGFR2, VEGFR3, FGFR1* and *FGFR2* with IC₅₀s of 7 nM, 25 nM, 10 nM, 17.5 nM, and 82.5 nM, respectively.

HY-109099

Pemigatinib 5+ Cited Publications INCB054828	FGFR	Cancer
Pemigatinib (INCB054828) is an orally active, selective *FGFR* inhibitor with IC₅₀s of 0.4 nM, 0.5 nM, 1.2 nM, 30 nM for FGFR1, FGFR2, FGFR3, FGFR4, respectively. Pemigatinib has the potential for cholangiocarcinoma ^[2].

HY-19981

Derazantinib 1 Publications Verification ARQ-087	FGFR	Cancer
Derazantinib (ARQ-087) is an ATP competitive and orally activeFGFR inhibitor (IC₅₀s: 1.8 nM for FGFR2, 4.5 nM for FGFR1 and 3 nM). Derazantinib inhibits FGFR phosphorylation. Derazantinib inhibits tumor growth in multiple xenograft models ^[2].

HY-101466A

E7090 succinate	FGFR	Cancer
E7090 succinate is an orally available, selective and potent inhibitor of **FGFR1, FGFR2 and FGFR3 tyrosine kinase activities, with IC₅₀** values of 0.71 nM, 0.50 nM, 1.2 nM, and 120 nM for FGFR1/2/3/4, respectively .

HY-19981B

Derazantinib dihydrochloride ARQ-087 dihydrochloride	EGFR	Cancer
Derazantinib (ARQ-087) dihydrochloride is an ATP competitive and orally activeFGFR inhibitor (IC₅₀s: 1.8 nM for FGFR2, 4.5 nM for FGFR1 and 3). Derazantinib dihydrochloride inhibits FGFR phosphorylation. Derazantinib dihydrochloride inhibits tumor growth in multiple xenograft models ^[2].

HY-101466

E7090

FGFR Cancer

E7090 is an orally available, potent, and selective FGFR inhibitor with IC₅₀s of 0.71 nM, 0.50 nM, 1.2 nM, and 120 nM for FGFR1/FGFR2/FGFR3/FGFR4, respectively .

E7090	FGFR	Cancer
E7090 is an orally available, potent, and selective *FGFR* inhibitor with IC₅₀s of 0.71 nM, 0.50 nM, 1.2 nM, and 120 nM for *FGFR1/FGFR2/FGFR3/FGFR4*, respectively .

HY-142921

FGFR-IN-2	FGFR	Cancer
FGFR-IN-2 (compound 1) is a potent *FGFR* inhibitor with IC₅₀s of 7.3 nM, 4.3 nM, 7.6 nM, 11 nM for FGFR1, FGFR2, FGFR3 and FGFR4, respectively. FGFR-IN-2 has the potential for cancer research .

HY-N7715

Ferulic acid acyl-β-D-glucoside Ferulic acid glucoside	Drug Metabolite	Others
Ferulic acid acyl-β-D-glucoside is a metabolite of Ferulic Acid (HY-N0060) . Ferulic acid is a novel fibroblast growth factor receptor 1 (FGFR1) inhibitor with IC₅₀s of 3.78 and 12.5 μM for FGFR1 and FGFR2, respectively ^[2].

HY-N9507

Picrasidine Q	Apoptosis FGFR	Cancer
Picrasidine Q, an alkaloid component extracted from Angelica keiskei species, has the capacity of anti-cell transformation and anti-cancer. Picrasidine Q induces cell apoptosis and G1 phase arrest in human esophageal cancer cell lines, and directly inhibits *FGFR2* kinase activity .

HY-152104

FGFR-IN-9	FGFR	Cancer
FGFR-IN-9 (Compound 19) is a potent, reversible and orally active *FGFR* inhibitor with an IC₅₀ of 17.1, 29.6, 30.7, 46.7 and 64.3 nM against FGFR4 ^WT, FGFR3, FGFR4 ^V550L, FGFR2 and FGFR1, respectively .

HY-101768

PRN1371 1 Publications Verification	FGFR c-Fms	Cancer
PRN1371 is a highly selective and potent *FGFR1-4* and CSF1R inhibitor with IC₅₀s of 0.6, 1.3, 4.1, 19.3 and 8.1 nM for FGFR1, FGFR2, FGFR3, FGFR4 and CSF1R, respectively .

HY-146541

FGFR4-IN-10	FGFR	Cancer
FGFR4-IN-10 (compound 5a) is a potent and selective *FGFR4* inhibitor with an IC₅₀ value of 70.7 nM. FGFR4-IN-10 shows no inhibition against other FGFR family members, i.e. FGFR1, FGFR2 and FGFR3 .

HY-100019

Rogaratinib 5 Publications Verification BAY1163877	FGFR	Cancer
Rogaratinib (BAY1163877) is a potent and selective fibroblast growth factor receptor (FGFR) inhibitor. Rogaratinib inhibits FGFRs with IC50s of 11.2 nM (FGFR1), <1 nM (FGFR2), 18.5 nM (FGFR3), 127 nM (VEGFR3/FLT4), 201 nM (FGFR4), respectively ^[2].

HY-10987A

ENMD-2076 3 Publications Verification	Aurora Kinase FLT3 VEGFR FGFR PDGFR Src Apoptosis	Cancer
ENMD-2076 is a multi-targeted kinase inhibitor with IC₅₀s of 1.86, 14, 58.2, 15.9, 92.7, 70.8, 56.4 nM for Aurora A, Flt3, *KDR/VEGFR2, Flt4/VEGFR3, FGFR1, FGFR2, Src, PDGFRα*, respectively.

HY-10987

ENMD-2076 Tartrate 3 Publications Verification	Aurora Kinase FLT3 VEGFR FGFR Src PDGFR Apoptosis	Cancer
ENMD-2076 Tartrate is a multi-targeted kinase inhibitor with IC₅₀s of 1.86, 14, 58.2, 15.9, 92.7, 70.8, 56.4 nM for Aurora A, Flt3, *KDR/VEGFR2, Flt4/VEGFR3, FGFR1, FGFR2, Src, PDGFRα*, respectively.

HY-163273

FGFR4-IN-17	FGFR	Cancer
FGFR4-IN-17 (Compound (S)-23) is a piperazinyl diflurindan derivative containing pyridinyl. FGFR4-IN-17 is a *FGFR* inhibitor with IC₅₀ values of 24.2, 16.1, 78.0, and 68.0 nM for FGFR1, FGFR2, FGFR3, and FGFR4, respectively. FGFR4-IN-17 has antitumor activity .

HY-10185

TG 100572 Hydrochloride 2 Publications Verification	Src VEGFR FGFR PDGFR	Inflammation/Immunology
TG 100572 Hydrochloride is a multi-targeted kinase inhibitor which inhibits receptor tyrosine kinases and Src kinases; has IC₅₀s of 2, 7, 2, 16, 13, 5, 0.5, 6, 0.1, 0.4, 1, 0.2 nM for VEGFR1, VEGFR2, FGFR1, FGFR2, PDGFRβ, Fgr, Fyn, Hck, Lck, Lyn, Src, Yes, respectively.

HY-10184

TG 100572	Src VEGFR PDGFR FGFR	Cancer
TG 100572 is a multi-targeted kinase inhibitor which inhibits receptor tyrosine kinases and Src kinases; has IC₅₀s of 2, 7, 2, 16, 13, 5, 0.5, 6, 0.1, 0.4, 1, 0.2 nM for VEGFR1, VEGFR2, FGFR1, FGFR2, PDGFRβ, Fgr, Fyn, Hck, Lck, Lyn, Src, Yes, respectively.

HY-128979

Deruxtecan analog 2	Drug-Linker Conjugates for ADC	Cancer
Deruxtecan analog 2 (example 9 P3) is a Deruxtecan (HY-13631E) analog. Deruxtecan analog 2 is a agent-linker conjugate composed of Camptothecin (HY-16560) and a linker. Camptothecin (CPT) is a Topo I inhibitor with antineoplastic activity against colorectal, breast, lung and ovarian cancers. Deruxtecan analog 2 can be used for the preparation anti-FGFR2 ADC .

HY-155028

FGFR-IN-11	FGFR	Cancer
FGFR-IN-11 (compound I-5) is an orally active and covalent *FGFR* inhibitor with IC₅₀ values of 9.9 nM (FGFR1), 3.1 nM (FGFR2), 16 nM (FGFR3), and 1.8 nM (FGFR4), respectively. FGFR-IN-11 inhibits multiple cancer cell proliferation with nanomolar activity. FGFR-IN-11 inhibits tumor growth significantly in xenograft mice models .

Cat. No.	Product Name	Target	Research Area

HY-P99007

Aprutumab BAY 1179470	FGFR	Cancer
Aprutumab (BAY 1179470) is a fully human *FGFR2* monoclonal antibody, which binds to the FGFR2 isoforms FGFR2-IIIb and FGFR2-IIIc. Aprutumab has the potential for solid tumors research .

Recombinant Proteins Recommended:

FGFR-2

Species:	Human (17) Mouse (3) Cynomolgus (1)
Tag:	His (14) Tag Free (1) Avi (5) GST (1) Fc (6)
Source:	HEK293 (19) Sf9 insect cells (2)

Cat. No.	Compare	Product Name	Species	Source

HY-P75764

	FGFR-1 alpha (IIIb) Protein, Human (HEK293, His) Fibroblast growth factor receptor 2; FGFR-2; FGF R2a; FGFR2 alpha	Human	HEK293
	FGFR-1 alpha, a conserved member of the FGFR family, binds acidic and basic fibroblast growth factors, influencing mitogenesis and differentiation. Mutations in FGFR1 cause syndromes and disorders. It exhibits ubiquitous expression, with notable levels in ovary (RPKM 21.8), fat (RPKM 21.4), and 25 other tissues. Alternatively spliced variants contribute to its functional diversity. FGFR-1 alpha (IIIb) Protein, Human (HEK293, His) is a recombinant protein dimer complex containing human-derived FGFR-1 alpha, expressed by HEK293 , with C-His, C-10*His labeled tag. FGFR-1 alpha (IIIb) Protein, Human (HEK293, His), has molecular weight of 60-90 kDa.

HY-P72645

	FGFR-2 alpha IIIc Protein, Human (HEK293, Fc) BEK, FGFR2IIIc; CD332; FGF R2b; FGFR2 beta; FGFR2; FGFR2b; Fibroblast growth factor receptor 2 (IIIc)	Human	HEK293
	The FGFR-2 α IIIc protein is a tyrosine protein kinase receptor for fibroblast growth factor and is critical for embryonic development, regulating proliferation, differentiation, and apoptosis. Its importance is evident in embryonic patterning, trophoblast function, limb bud development, lung morphogenesis, osteogenesis, and skin development. FGFR-2 alpha IIIc Protein, Human (HEK293, Fc) is the recombinant human-derived FGFR-2 alpha IIIc protein, expressed by HEK293 , with C-hFc labeled tag. The total length of FGFR-2 alpha IIIc Protein, Human (HEK293, Fc) is 356 a.a., with molecular weight of 85-120 kDa.

HY-P75763

	FGFR-1 alpha (IIIb) Protein, Human (HEK293, Fc) Fibroblast growth factor receptor 2; FGFR-2; FGF R2a; FGFR2 alpha	Human	HEK293
	FGFR-1 alpha, a conserved member of the FGFR family, binds acidic and basic fibroblast growth factors, influencing mitogenesis and differentiation. Mutations in FGFR1 cause syndromes and disorders. It exhibits ubiquitous expression, with notable levels in ovary (RPKM 21.8), fat (RPKM 21.4), and 25 other tissues. Alternatively spliced variants contribute to its functional diversity. FGFR-1 alpha (IIIb) Protein, Human (HEK293, Fc) is a recombinant protein dimer complex containing human-derived FGFR-1 alpha, expressed by HEK293, with C-hFc labeled tag. FGFR-1 alpha (IIIb) Protein, Human (HEK293, Fc), has molecular weight of ~113.3 kDa.

HY-P72647

	FGFR-2 beta IIIc Protein, Human (HEK293, Fc) Fibroblast growth factor receptor 2; FGFR-2; FGF R2a; FGFR2 alpha	Human	HEK293
	The FGFR-2 α IIIc protein is a tyrosine protein kinase receptor for fibroblast growth factor and is critical for embryonic development, regulating proliferation, differentiation, and apoptosis. Its importance is evident in embryonic patterning, trophoblast function, limb bud development, lung morphogenesis, osteogenesis, and skin development. FGFR-2 beta IIIc Protein, Human (HEK293, Fc) is the recombinant human-derived FGFR-2 beta IIIc protein, expressed by HEK293 , with C-hFc labeled tag. The total length of FGFR-2 beta IIIc Protein, Human (HEK293, Fc) is 226 a.a., with molecular weight of 72-95 kDa.

HY-P72646

	FGFR-2 beta IIIb Protein, Human (HEK293, His) BFR-1; FGFR2IIIb; KGFR; CD332; FGF R2b; FGFR2 beta; FGFR2; FGFR2b; Fibroblast growth factor receptor 2 (IIIb)	Human	HEK293
	The FGFR-2 α IIIc protein is a tyrosine protein kinase receptor for fibroblast growth factor and is critical for embryonic development, regulating proliferation, differentiation, and apoptosis. Its importance is evident in embryonic patterning, trophoblast function, limb bud development, lung morphogenesis, osteogenesis, and skin development. FGFR-2 beta IIIb Protein, Human (HEK293, His) is the recombinant human-derived FGFR-2 beta IIIb protein, expressed by HEK293 , with C-6*His labeled tag. The total length of FGFR-2 beta IIIb Protein, Human (HEK293, His) is 227 a.a., with molecular weight of 40-70 kDa.

HY-P78125

	FGFR-2 alpha IIIb Protein, Human (Biotinylated, HEK293, His-Avi) FGF R2a; FGFR2 alpha; KGFR; CD332; BBDS; BEK; BFR-1; CEK3; CFD1; ECT1; JWS; K-SAM; KGFR; TK14; TK25; FLJ98662	Human	HEK293
	The FGFR-2 α IIIc protein is a tyrosine protein kinase receptor for fibroblast growth factor and is critical for embryonic development, regulating proliferation, differentiation, and apoptosis. Its importance is evident in embryonic patterning, trophoblast function, limb bud development, lung morphogenesis, osteogenesis, and skin development. FGFR-2 alpha IIIb Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived FGFR-2 alpha IIIb protein, expressed by HEK293 , with C-Avi, C-His labeled tag. The total length of FGFR-2 alpha IIIb Protein, Human (Biotinylated, HEK293, His-Avi) is 357 a.a., with molecular weight of 70-110 kDa.

HY-P78131

	FGFR-2 alpha IIIc Protein, Human (Biotinylated, HEK293, His-Avi) FGF R2a; FGFR2 alpha; KGFR; CD332; BBDS; BEK; BFR-1; CEK3; CFD1; ECT1; JWS; K-SAM; KGFR; TK14; TK25; FLJ98662	Human	HEK293
	The FGFR-2 α IIIc protein is a tyrosine protein kinase receptor for fibroblast growth factor and is critical for embryonic development, regulating proliferation, differentiation, and apoptosis. Its importance is evident in embryonic patterning, trophoblast function, limb bud development, lung morphogenesis, osteogenesis, and skin development. FGFR-2 alpha IIIc Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived FGFR-2 alpha IIIc protein, expressed by HEK293 , with C-His, C-Avi labeled tag. The total length of FGFR-2 alpha IIIc Protein, Human (Biotinylated, HEK293, His-Avi) is 356 a.a., with molecular weight of 70-80 kDa.

HY-P76339

	FGFR-2 Protein, Mouse (HEK293, Fc) Fibroblast growth factor receptor 2; FGFR-2; KSAM; KGFR; CD332; BEK	Mouse	HEK293
	FGFR2, also known as CD332 (differentiated cluster 332), is a receptor for fibroblast growth factor. FGFR2 is involved in activation of RAS, MAPK1/ERK2, MAPK3/ERK1, MAP kinase signaling pathways, and AKT1 signaling pathways. FGFR2 up-regulates PAI-1 via JAK2/STAT3 signaling and induces M2 polarization in colorectal cancer macrophages. FGFR-2 Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived FGFR-2 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of FGFR-2 Protein, Mouse (HEK293, Fc) is 242 a.a., with molecular weight of ~89.9 KDa.

HY-P76340

FGFR-2 Protein, Mouse (HEK293, His)

Fibroblast growth factor receptor 2; FGFR-2; KSAM; KGFR; CD332; BEK
Mouse HEK293

HY-P76333

	FGFR-2 Protein, Human (sf9, His-GST) Fibroblast growth factor receptor 2; FGFR-2; KSAM; KGFR; CD332; BEK	Human	Sf9 insect cells
	The FGFR-2 α IIIc protein is a tyrosine protein kinase receptor for fibroblast growth factor and is critical for embryonic development, regulating proliferation, differentiation, and apoptosis. Its importance is evident in embryonic patterning, trophoblast function, limb bud development, lung morphogenesis, osteogenesis, and skin development. FGFR-2 Protein, Human (sf9, His-GST) is the recombinant human-derived FGFR-2 protein, expressed by Sf9 insect cells , with N-His, N-GST labeled tag. The total length of FGFR-2 Protein, Human (sf9, His-GST) is 422 a.a., with molecular weight of ~68 KDa.

HY-P76334

	FGFR-2 alpha IIIb Protein, Human (HEK293, Fc) Fibroblast growth factor receptor 2; FGFR-2; KSAM; KGFR; CD332; BEK	Human	HEK293
	The FGFR-2 α IIIc protein is a tyrosine protein kinase receptor for fibroblast growth factor and is critical for embryonic development, regulating proliferation, differentiation, and apoptosis. Its importance is evident in embryonic patterning, trophoblast function, limb bud development, lung morphogenesis, osteogenesis, and skin development. FGFR-2 alpha IIIb Protein, Human (HEK293, Fc) is the recombinant human-derived FGFR-2 alpha IIIb protein, expressed by HEK293 , with C-hFc labeled tag. The total length of FGFR-2 alpha IIIb Protein, Human (HEK293, Fc) is 357 a.a., with molecular weight of 80-115 KDa.

HY-P76336

	FGFR-2 alpha IIIb Protein, Human (HEK293, His) Fibroblast growth factor receptor 2; FGFR-2; KSAM; KGFR; CD332; BEK	Human	HEK293
	The FGFR-2 α IIIc protein is a tyrosine protein kinase receptor for fibroblast growth factor and is critical for embryonic development, regulating proliferation, differentiation, and apoptosis. Its importance is evident in embryonic patterning, trophoblast function, limb bud development, lung morphogenesis, osteogenesis, and skin development. FGFR-2 alpha IIIb Protein, Human (HEK293, His) is the recombinant human-derived FGFR-2 alpha IIIb protein, expressed by HEK293 , with C-His labeled tag. The total length of FGFR-2 alpha IIIb Protein, Human (HEK293, His) is 357 a.a., with molecular weight of 60-80 KDa.

HY-P76337

	FGFR-2 alpha IIIc Protein, Human (HEK293, His) Fibroblast growth factor receptor 2; FGFR-2; KSAM; KGFR; CD332; BEK	Human	HEK293
	The FGFR-2 α IIIc protein is a tyrosine protein kinase receptor for fibroblast growth factor and is critical for embryonic development, regulating proliferation, differentiation, and apoptosis. Its importance is evident in embryonic patterning, trophoblast function, limb bud development, lung morphogenesis, osteogenesis, and skin development. FGFR-2 alpha IIIc Protein, Human (HEK293, His) is the recombinant human-derived FGFR-2 alpha IIIc protein, expressed by HEK293 , with C-His labeled tag. The total length of FGFR-2 alpha IIIc Protein, Human (HEK293, His) is 356 a.a., with molecular weight of 60-80 KDa.

HY-P76338

	FGFR-2 alpha IIIc Protein, Human (HEK293, His-Fc) Fibroblast growth factor receptor 2; FGFR-2; KSAM; KGFR; CD332; BEK	Human	HEK293
	The FGFR-2 α IIIc protein is a tyrosine protein kinase receptor for fibroblast growth factor and is critical for embryonic development, regulating proliferation, differentiation, and apoptosis. Its importance is evident in embryonic patterning, trophoblast function, limb bud development, lung morphogenesis, osteogenesis, and skin development. FGFR-2 alpha IIIc Protein, Human (HEK293, His-Fc) is the recombinant human-derived FGFR-2 alpha IIIc protein, expressed by HEK293 , with C-hFc, C-His labeled tag. The total length of FGFR-2 alpha IIIc Protein, Human (HEK293, His-Fc) is 356 a.a., with molecular weight of 110-120 KDa.

HY-P76335

	FGFR-2 beta IIIc Protein, Human (267a.a, HEK293, His) Fibroblast growth factor receptor 2; FGFR-2; KSAM; KGFR; CD332; BEK	Human	HEK293
	The FGFR-2 beta IIIc protein is part of the fibroblast growth factor receptor family and has a conserved sequence. Its full-length structure includes an extracellular immunoglobulin-like domain, a transmembrane segment, and a tyrosine kinase domain. FGFR-2 beta IIIc Protein, Human (267a.a, HEK293, His) is the recombinant human-derived FGFR-2 beta IIIc protein, expressed by HEK293 , with C-His labeled tag. The total length of FGFR-2 beta IIIc Protein, Human (267a.a, HEK293, His) is 267 a.a., with molecular weight of ~31.2 KDa.

HY-P702759

FGFR-2 Protein, Human (Biotinylated, sf9)

Fibroblast growth factor receptor 2; FGFR-2; KSAM; KGFR; CD332; BEK
Human Sf9 insect cells

HY-P77653

	FGFR-2 beta (IIIb) Protein, Cynomolgus (HEK293, His) Fibroblast growth factor receptor 2; FGFR-2; KGFR; K-sam; Keratinocyte growth factor receptor; CD332; BEK; KSAM	Cynomolgus	HEK293
	FGFR-2 beta is a tyrosine protein kinase that serves as a cell surface receptor for fibroblast growth factor and is critical for cell regulation, proliferation, differentiation, migration, and apoptosis. It plays important roles in embryonic development, trophoblast function, limb buds, lungs, osteogenesis, and skin development. FGFR-2 beta (IIIb) Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived FGFR-2 beta, expressed by HEK293 , with C-His labeled tag. The total length of FGFR-2 beta (IIIb) Protein, Cynomolgus (HEK293, His) is 215 a.a., with molecular weight of 50-68 kDa.

HY-P77661

	FGFR-2 beta (IIIb) Protein, Mouse (HEK293, His) Fibroblast growth factor receptor 2; FGFR-2; KGFR; K-sam; Keratinocyte growth factor receptor; CD332; BEK; KSAM	Mouse	HEK293
	FGFR-2 beta is a tyrosine protein kinase that serves as a cell surface receptor for fibroblast growth factor and is critical for cell regulation, proliferation, differentiation, migration, and apoptosis. It plays important roles in embryonic development, trophoblast function, limb buds, lungs, osteogenesis, and skin development. FGFR-2 beta (IIIb) Protein, Mouse (HEK293, His) is the recombinant mouse-derived FGFR-2 beta, expressed by HEK293 , with C-His labeled tag. The total length of FGFR-2 beta (IIIb) Protein, Mouse (HEK293, His) is 225 a.a., with molecular weight of 50-70 kDa.

HY-P700986

	FGFR-2 beta IIIb Protein, Human (HEK293, Avi) Fibroblast growth factor receptor 2; FGFR-2; KGFR; K-sam; Keratinocyte growth factor receptor; CD332; BEK; KSAM	Human	HEK293
	The FGFR-2 α IIIc protein is a tyrosine protein kinase receptor for fibroblast growth factor and is critical for embryonic development, regulating proliferation, differentiation, and apoptosis. Its importance is evident in embryonic patterning, trophoblast function, limb bud development, lung morphogenesis, osteogenesis, and skin development. FGFR-2 beta IIIb Protein, Human (HEK293, Avi) is the recombinant human-derived FGFR-2 beta IIIb protein, expressed by HEK293 , with C-Avi labeled tag. The total length of FGFR-2 beta IIIb Protein, Human (HEK293, Avi) is 126 a.a., with molecular weight of 35-50 kDa.

HY-P78129

	FGFR-2 beta IIIb Protein, Human (Biotinylated, HEK293, His-Avi) Fibroblast growth factor receptor 2; FGFR-2; KGFR; K-sam; Keratinocyte growth factor receptor; CD332; BEK; KSAM	Human	HEK293
	The FGFR-2 α IIIc protein is a tyrosine protein kinase receptor for fibroblast growth factor and is critical for embryonic development, regulating proliferation, differentiation, and apoptosis. Its importance is evident in embryonic patterning, trophoblast function, limb bud development, lung morphogenesis, osteogenesis, and skin development. FGFR-2 beta IIIb Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived FGFR-2 beta IIIb protein, expressed by HEK293 , with C-Avi, C-His labeled tag. The total length of FGFR-2 beta IIIb Protein, Human (Biotinylated, HEK293, His-Avi) is 227 a.a., with molecular weight of 48-60 kDa.

HY-P78130

	FGFR-2 beta IIIc Protein, Human (Biotinylated, HEK293, His-Avi) Fibroblast growth factor receptor 2; FGFR-2; KGFR; K-sam; Keratinocyte growth factor receptor; CD332; BEK; KSAM	Human	HEK293
	The FGFR-2 α IIIc protein is a tyrosine protein kinase receptor for fibroblast growth factor and is critical for embryonic development, regulating proliferation, differentiation, and apoptosis. Its importance is evident in embryonic patterning, trophoblast function, limb bud development, lung morphogenesis, osteogenesis, and skin development. FGFR-2 beta IIIc Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived FGFR-2 beta IIIc protein, expressed by HEK293 , with C-Avi, C-His labeled tag. The total length of FGFR-2 beta IIIc Protein, Human (Biotinylated, HEK293, His-Avi) is 226 a.a., with molecular weight of 48-60 kDa.

Cat. No.	Product Name	Application	Reactivity

HY-P80397

FGFR2 Antibody	WB, IP	Human
FGFR2 Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 92 kDa, targeting to FGFR2. It can be used for WB,IP assays with tag free, in the background of Human.

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