FGFR-IN-1
Based on 1 Customer Validation
FGFR-IN-1 is a potent FGFR inhibitor with an IC50 of <100 nM for FGFR1, FGFR2, and FGFR3, respectively (patent US20130338134A1, example 219).
For research use only. We do not sell to patients.
- Purity: 99.46%
- CAS No.: 1513860-41-7
- Formula: C26H24F2N4O6S
- Molecular Weight:558.55
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Storage:
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
Chemical Information
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CAS No. 1513860-41-7
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Appearance Solid
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Molecular Weight 558.55
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Formula C26H24F2N4O6S
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Color Off-white to light yellow
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SMILES
O=C1N(CC2=CN=C3C(C=C(CO)N3S(=O)(C4=CC=CC=C4)=O)=C2N1CC)C5=C(F)C(OC)=CC(OC)=C5F
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Solvent & Solubility
DMSO : 50 mg/mL (89.52 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (270 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.7904 mL | 8.9518 mL | 17.9035 mL | 44.7588 mL |
| 5 mM | 0.3581 mL | 1.7904 mL | 3.5807 mL | 8.9518 mL | |
| 10 mM | 0.1790 mL | 0.8952 mL | 1.7904 mL | 4.4759 mL | |
| 15 mM | 0.1194 mL | 0.5968 mL | 1.1936 mL | 2.9839 mL | |
| 20 mM | 0.0895 mL | 0.4476 mL | 0.8952 mL | 2.2379 mL | |
| 25 mM | 0.0716 mL | 0.3581 mL | 0.7161 mL | 1.7904 mL | |
| 30 mM | 0.0597 mL | 0.2984 mL | 0.5968 mL | 1.4920 mL | |
| 40 mM | 0.0448 mL | 0.2238 mL | 0.4476 mL | 1.1190 mL | |
| 50 mM | 0.0358 mL | 0.1790 mL | 0.3581 mL | 0.8952 mL | |
| 60 mM | 0.0298 mL | 0.1492 mL | 0.2984 mL | 0.7460 mL | |
| 80 mM | 0.0224 mL | 0.1119 mL | 0.2238 mL | 0.5595 mL |
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