Search Result
Results for "
PNAs
" in MedChemExpress (MCE) Product Catalog:
Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-P6027A
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Fluorescent Dye
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Others
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H-D-CHA-Ala-Arg-pNA (diacetate) is the diacetate form of H-D-CHA-Ala-Arg-pNA (HY-150523). H-D-CHA-Ala-Arg-pNA (diacetate) is a chromogenic substrate for the amidolytic assay .
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- HY-P10001
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Z-Ile-Glu-Thr-Asp-pNA
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Caspase
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Cancer
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Z-IETD-pNA (Z-Ile-Glu-Thr-Asp-pNA) is a colorimetric caspase-8 and granzyme B substrate. Z-IETD-pNA is hydrlyzed by caspase 8 to generate pNA .
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- HY-151778
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ADC Linker
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Others
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Fmoc-Abg(N3)-OH is a click chemistry reagent containing an azide group. Fmoc-Abg(N3)-OH has the potential to synthesize peptide nucleic acids (PNA) and peptoids.
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- HY-151738
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ADC Linker
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Others
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Fmoc-Aeg(N3)-OH is a click chemistry reagent containing an Azide. Alkylating the Nitrogen of an amide bond results in peptoid structures, which leads to conformational restrains, like N-methylation and allows backbone derivatisation. Altering cytotoxicity, bacterial cell selectivity and receptor pharmacology through formation of peptoid derivatives have been published for Cilengitide, Piscidin 1, and MC3, MC4 and MC5 receptor agonist. This building block enables design of macrocycles through intermolecular crosslinking or backbone stabilization through intermolecular ring-closure. This compound is a potential building block for the construction of (customized) peptide nucleic acids (PNAs) and for peptoid synthesis . Fmoc-Aeg(N3)-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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- HY-P5974
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Z-Tyr-Val-Ala-Asp-pNA
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Caspase
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Others
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Z-YVAD-pNA (Z-Tyr-Val-Ala-Asp-pNA) is a caspase-1 substrate .
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- HY-P10094
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Fluorescent Dye
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Others
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β-Ala-Gly-Arg-pNA is a chromogenic substrate of thrombin with pNA a strong absorbance at 405 nm .
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- HY-114150D
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Kallikrein
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Others
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D-Val-Leu-Arg-pNA (acetate) is the acetate form of D-Pro-Phe-Arg-p-nitroanilide (pNa). D-Pro-Phe-Arg-p-nitroanilide (pNa) is the substrate for kallikrein and can be used to assay the activity of kallikrein .
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- HY-P4458
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Ser/Thr Protease
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Cancer
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Boc-QAR-pNA is a chromogenic substrate of trypsin. Boc-QAR-pNA can be used to test trypsin activity .
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- HY-P4476
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Ser/Thr Protease
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Others
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Suc-AAPA-pNA is a substrate of chymotrypsin Aα. Suc-AAPA-pNA can be used to test chymotrypsin Aα activity .
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- HY-P4581
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Suc-ALPF-pNA
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FKBP
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Others
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Suc-Ala-Leu-Pro-Phe-pNA (Suc-ALPF-pNA) is a substrate of FK-506 binding protein (FKBP) .
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- HY-P4455
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Bacterial
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Infection
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Boc-AAG-pNA is a glycine endopeptidase substrate. Boc-AAG-pNA can be used to test the amidase activity glycine endopeptidase .
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- HY-P4460
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Ser/Thr Protease
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Cancer
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AAA-pNA is a chromogenic substrate of Tripeptidyl-peptidase II. AAA-pNA can be used to test Tripeptidyl-peptidase II activity .
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- HY-P4482
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Bacterial
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Infection
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Suc-AAPE-pNA is a chromogenic substrate of glutamyl endopeptidase. Suc-AAPE-pNA can be used to test glutamyl endopeptidase activity .
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- HY-W713878
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Caspase
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Others
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Ac-VDVAD-pNA is a caspase-2 substrate. Ac-VDVAD-pNA can be used to test the activity of caspase-2 .
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- HY-P10084
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Caspase
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Others
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Ac-VAD-pNA is a caspase-1 substrate. Ac-VAD-pNA can be used to detect caspase-1 activity .
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- HY-P4464
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Ser/Thr Protease
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Cancer
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Ala-Phe-Pro-pNA is a chromogenic substrate of tripeptidyl peptidase. Ala-Phe-Pro-pNA can be used to test tripeptidyl peptidase activity .
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- HY-P4470
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Ser/Thr Protease
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Cancer
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Phe-Pro-Ala-pNA is a chromogenic substrate of tripeptidyl peptidase. Phe-Pro-Ala-pNA can be used to test tripeptidyl peptidase activity .
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- HY-P4477
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Ser/Thr Protease
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Others
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Suc-AAPR-pNA is a substrate of trypsin acyl-enzymes. Suc-AAPR-pNA can be used to test trypsin acyl-enzymes activity .
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- HY-P4518
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Ser/Thr Protease
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Others
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Z-Val-Gly-Arg-pNA is a chromogenic substrate for urokinase. Z-Val-Gly-Arg-pNA can be used for determination of urokinase activity .
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- HY-P2610
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Caspase
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Others
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Ac-VEID-pNA is an artificially synthesized peptide. Ac-VEID-pNA is utilized as substrate for caspase 6, that cleaves the lamin A at the cleavage site of VEID .
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- HY-P4202
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Suc-AEPF-pNA
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Biochemical Assay Reagents
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Others
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Suc-Ala-Glu-Pro-Phe-pNA (Suc-AEPF-pNA) is a chromogenic substrate for the peptidylprolyl isomerase Pin1. Suc-Ala-Glu-Pro-Phe-pNA can be used to evaluate the inhibitory effect of the target compound on Pin1, and catalytic activity of Pin1, etc .
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- HY-P4475
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- HY-P4202A
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Suc-AEPF-pNA TFA
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Biochemical Assay Reagents
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Others
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Suc-Ala-Glu-Pro-Phe-pNA (Suc-AEPF-pNA ) TFA is a chromogenic substrate for the peptidylprolyl isomerase Pin1. Suc-Ala-Glu-Pro-Phe-pNA TFA can be used to evaluate the inhibitory effect of the target compound on Pin1, and catalytic activity of Pin1, etc .
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- HY-P4453
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Caspase
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Cancer
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Boc-Ala-Ala-Asp-pNA is a chromogenic substrate of granzyme B. Boc-Ala-Ala-Asp-pNA can be used to test functional activity of granzyme B .
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- HY-119244
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Dipeptidyl Peptidase
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Others
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Gly-Pro-pNA hydrochloride is a chromogenic substrate that can be cleaved by the circulating enzyme, dipeptidyl peptidase IV (DPP IV). Gly-Pro-pNA can be used to screen for DPP IV inhibitors .
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- HY-W011701
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- HY-P2091
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Caspase
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Inflammation/Immunology
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Ac-YVAD-pNA is a specific Caspase-1 substrate. Ac-YVAD-pNA can be used to detect Caspase-1 activity. Caspase-1 is a key mediator of inflammatory processes .
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- HY-P4515
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- HY-147167
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- HY-148415
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- HY-P10083
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- HY-W011155
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- HY-123275A
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S-2238 hydrochloride
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Fluorescent Dye
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Others
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H-D-Phe-Pip-Arg-pNA (S-2238) hydrochloride, a chromogenic substrate, is patterned after the N-terminal portion of the A alpha chain of fibrinogen, which is the natural substrate of thrombin. H-D-Phe-Pip-Arg-pNA hydrochloride is specific for thrombin and is used to measure antithrombin-heparin cofactor (AT-III). The AT-III assay using H-D-Phe-Pip-Arg-pNA hydrochloride is sensitive, accurate, and easy to perform .
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- HY-123275
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S-2238
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Fluorescent Dye
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Others
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H-D-Phe-Pip-Arg-pNA (S-2238), a chromogenic substrate, is patterned after the N-terminal portion of the A alpha chain of fibrinogen, which is the natural substrate of thrombin. H-D-Phe-Pip-Arg-pNA is specific for thrombin and is used to measure antithrombin-heparin cofactor (AT-III). The AT-III assay using H-D-Phe-Pip-Arg-pNA is sensitive, accurate, and easy to perform .
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- HY-123275C
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S-2238 dihydrochloride
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Fluorescent Dye
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Others
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H-D-Phe-Pip-Arg-pNA (S-2238) dihydrochloride, a chromogenic substrate, is patterned after the N-terminal portion of the A alpha chain of fibrinogen, which is the natural substrate of thrombin. H-D-Phe-Pip-Arg-pNA dihydrochloride is specific for thrombin and is used to measure antithrombin-heparin cofactor (AT-III). The AT-III assay using H-D-Phe-Pip-Arg-pNA dihydrochloride is sensitive, accurate, and easy to perform .
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- HY-123275B
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S-2238 acetate
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Fluorescent Dye
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Others
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H-D-Phe-Pip-Arg-pNA (S-2238) acetate, a chromogenic substrate, is patterned after the N-terminal portion of the A alpha chain of fibrinogen, which is the natural substrate of thrombin. H-D-Phe-Pip-Arg-pNA acetate is specific for thrombin and is used to measure antithrombin-heparin cofactor (AT-III). The AT-III assay using H-D-Phe-Pip-Arg-pNA acetate is sensitive, accurate, and easy to perform .
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- HY-P0021A
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Spectrozyme PCa; Chromozym Pca diacetate
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Fluorescent Dye
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Others
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D-Lys(Z)-Pro-Arg-pNA diacetate (Spectrozyme PCa) is a chromogenic substrate.
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- HY-137220
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- HY-P1006
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Caspase
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Others
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Ac-DEVD-pNA is a colorimetric substrate for caspase-3 (CPP32) and related cysteine proteases.
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- HY-137186
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Proteasome
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Others
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Suc-Gly-Gly-Phe-pNA is the chymotrypsin substrate with an Km value of 1.6 mM .
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- HY-148372
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- HY-P3936
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Fluorescent Dye
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Others
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Endotoxin Substrate (Boc-LGR-pNA) is a chromogenic substrate can be used in quantitative assays of endotoxin .
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- HY-P4468
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- HY-P4500
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Cathepsin
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Others
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Z-Arg-Arg-pNA is a substrate for cathepsin B and can be used to detect this enzyme activity .
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- HY-P0021
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Chromozym Pca
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Fluorescent Dye
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Others
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D-Lys(Z)-Pro-Arg-pNA (Chromozym Pca) is a luminescent substrate of activated protein C (APC).
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- HY-P3126
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Factor Xa
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Others
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Suc-Ile-Glu(γ-pip)-Gly-Arg-pNA hydrochloride is a factor Xa specific chromogenic substrate .
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- HY-P4490
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- HY-P4494
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Cathepsin
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Others
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Suc-Val-Pro-Phe-pNA is a substrate for cathepsin G and can be used to detect the activity of this enzyme .
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- HY-P2685
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Fluorescent Dye
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Others
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MeOSuc-Ala-Ala-Pro-Val-pNA is a sensitive fluorogenic substrate of human leukocyte and porcine pancreatic elastase .
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- HY-W540122
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- HY-153829
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- HY-P10236
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Caspase
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Others
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Ac-WEHD-pNA is a colorimetric substrate for caspase 1, 4, 5 and 14, which is utilized to measure the caspase activity .
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- HY-126785
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Colorimetric Elastase Substrate
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Elastase
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Others
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Suc-AAP-Abu-pNA (Colorimetric Elastase Substrate) is a specific substrate for pancreatic elastase (Km = 100 μM; Kcat/Km = 35,300 s -1 M -1 for rat pancreatic elastase; Km = 30 μM; Kcat/Km = 351,000 s -1 M -1 for porcine pancreatic elastase). Suc-AAP-Abu-pNA also promotes OPC migration .
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- HY-P4576
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Factor Xa
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Others
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Methoxycarbonyl-D-Nle-Gly-Arg-pNA is a synthetic trypsin that can serve as a substrate for coagulation factors IXa (FIXa) and Xa (FXa) .
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- HY-151828
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ADC Linker
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Others
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N3-Gly-Aeg(Fmoc)-OH is a click chemistry reagent containing an azide group. PNA building-block that can be further modified using Click-chemistry .
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- HY-P4039
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HCV Protease
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Infection
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Ac-EEVVAC-pNA is a chromogenic substrate for a continuous spectrophotometric assay of HCV NS3 protease. The sequence EEVVAC is derived from the 5A-5B cleavage junction of the HCV polyprotein .
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- HY-W008129
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Endogenous Metabolite
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Metabolic Disease
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cis-4-Hydroxy-D-proline is a precursor of conformationally restricted PNA adenine monomer. cis-4-Hydroxy-D-proline can be used to study the specificity and kinetics of D-alanine dehydrogenase .
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- HY-120833
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Caspase
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Others
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Ac-Ile-Glu-Thr-Asp-pNA is a substrate for caspase-8. Caspase-8 binds to and cleaves the Ile-Glu-Thr-Asp (IETD) peptide sequence to release p-nitroalinide, which can be quantified by colorimetric detection at 405 nm as a measure of enzyme activity .
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- HY-P3480
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Fluorescent Dye
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Others
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H-Trp-Phe-Tyr-Ser(PO3H2)-Pro-Arg-pNA is a chromogenic substrate for Pin1. Pin1 is an essential and conserved mitotic peptidyl-prolyl isomerase, and can recognize the phosphoserine-proline bonds present in mitotic phosphoproteins .
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Cat. No. |
Product Name |
Type |
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- HY-P4202
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Suc-AEPF-pNA
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Chromogenic Substrates
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Suc-Ala-Glu-Pro-Phe-pNA (Suc-AEPF-pNA) is a chromogenic substrate for the peptidylprolyl isomerase Pin1. Suc-Ala-Glu-Pro-Phe-pNA can be used to evaluate the inhibitory effect of the target compound on Pin1, and catalytic activity of Pin1, etc .
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- HY-P0021A
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Spectrozyme PCa; Chromozym Pca diacetate
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Chromogenic Substrates
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D-Lys(Z)-Pro-Arg-pNA diacetate (Spectrozyme PCa) is a chromogenic substrate.
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- HY-P2685
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Chromogenic Substrates
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MeOSuc-Ala-Ala-Pro-Val-pNA is a sensitive fluorogenic substrate of human leukocyte and porcine pancreatic elastase .
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- HY-P4202A
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Suc-AEPF-pNA TFA
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Chromogenic Substrates
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Suc-Ala-Glu-Pro-Phe-pNA (Suc-AEPF-pNA ) TFA is a chromogenic substrate for the peptidylprolyl isomerase Pin1. Suc-Ala-Glu-Pro-Phe-pNA TFA can be used to evaluate the inhibitory effect of the target compound on Pin1, and catalytic activity of Pin1, etc .
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- HY-P0021
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Chromozym Pca
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Chromogenic Substrates
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D-Lys(Z)-Pro-Arg-pNA (Chromozym Pca) is a luminescent substrate of activated protein C (APC).
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- HY-P3236
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Ac-IEPD-pNA
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Fluorescent Dyes/Probes
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N-Acetyl-Ile-Glu-Pro-Asp-p-nitroanilide (Ac-IEPD-pNA) is a granzyme B substrate that allows accurate measurement of granzyme B activity .
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- HY-P4039
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Chromogenic Substrates
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Ac-EEVVAC-pNA is a chromogenic substrate for a continuous spectrophotometric assay of HCV NS3 protease. The sequence EEVVAC is derived from the 5A-5B cleavage junction of the HCV polyprotein .
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Cat. No. |
Product Name |
Target |
Research Area |
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- HY-P2573
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Suc-Ala-Ala-Pro-Phe-pNA
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Peptides
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Others
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Suc-AAPF-pNA (Suc-Ala-Ala-Pro-Phe-pNA) is a chromogenic p-nitroanilide (pNA) substrate with the Km of 1.7 mM. Cleavage of Suc-AAPF-pNA releases 4-nitroaniline, which is yellow in colour and can be measured spectrophotometrically. Suc-AAPF-pNA can be used for the measurement of free and membrane-bound cathepsin G in human neutrophils .
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- HY-P6027A
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Fluorescent Dye
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Others
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H-D-CHA-Ala-Arg-pNA (diacetate) is the diacetate form of H-D-CHA-Ala-Arg-pNA (HY-150523). H-D-CHA-Ala-Arg-pNA (diacetate) is a chromogenic substrate for the amidolytic assay .
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- HY-P10001
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Z-Ile-Glu-Thr-Asp-pNA
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Caspase
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Cancer
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Z-IETD-pNA (Z-Ile-Glu-Thr-Asp-pNA) is a colorimetric caspase-8 and granzyme B substrate. Z-IETD-pNA is hydrlyzed by caspase 8 to generate pNA .
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- HY-P5348
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Peptides
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Others
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Ac-LEHD-pNA is a biological active peptide. (Caspase-9 substrate; pNA (4-nitroaniline)-derived caspase substrates are widely used for the colorimetric detection of various caspase activities. Cleavage of pNA peptides by caspases generates pNA that is monitored colorimetrically at ~405 nm. pNA has maximum absorption around 408 nm.)
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- HY-P4461
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Peptides
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Others
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Ala-Ala-Pro-pNA is a tripeptide, including chromophoric amino acids Pro-pNA. Ala-Ala-Pro-pNA is targeted by tripeptidyl aminopeptidase (SM-TAP) .
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- HY-P5974
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Z-Tyr-Val-Ala-Asp-pNA
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Caspase
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Others
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Z-YVAD-pNA (Z-Tyr-Val-Ala-Asp-pNA) is a caspase-1 substrate .
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- HY-P10094
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Fluorescent Dye
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Others
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β-Ala-Gly-Arg-pNA is a chromogenic substrate of thrombin with pNA a strong absorbance at 405 nm .
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- HY-114150D
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Kallikrein
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Others
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D-Val-Leu-Arg-pNA (acetate) is the acetate form of D-Pro-Phe-Arg-p-nitroanilide (pNa). D-Pro-Phe-Arg-p-nitroanilide (pNa) is the substrate for kallikrein and can be used to assay the activity of kallikrein .
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- HY-P4458
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Ser/Thr Protease
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Cancer
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Boc-QAR-pNA is a chromogenic substrate of trypsin. Boc-QAR-pNA can be used to test trypsin activity .
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- HY-P4476
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Ser/Thr Protease
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Others
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Suc-AAPA-pNA is a substrate of chymotrypsin Aα. Suc-AAPA-pNA can be used to test chymotrypsin Aα activity .
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- HY-P4581
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Suc-ALPF-pNA
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FKBP
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Others
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Suc-Ala-Leu-Pro-Phe-pNA (Suc-ALPF-pNA) is a substrate of FK-506 binding protein (FKBP) .
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- HY-P4455
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Bacterial
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Infection
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Boc-AAG-pNA is a glycine endopeptidase substrate. Boc-AAG-pNA can be used to test the amidase activity glycine endopeptidase .
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- HY-P4460
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Ser/Thr Protease
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Cancer
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AAA-pNA is a chromogenic substrate of Tripeptidyl-peptidase II. AAA-pNA can be used to test Tripeptidyl-peptidase II activity .
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- HY-P4482
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Bacterial
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Infection
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Suc-AAPE-pNA is a chromogenic substrate of glutamyl endopeptidase. Suc-AAPE-pNA can be used to test glutamyl endopeptidase activity .
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- HY-125128
-
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Peptides
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Others
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Glp-Pro-Val-pNA is a granulocyte elastase substrate. Glp-Pro-Val-pNA can be used to quantify the release of elastase .
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- HY-P3939
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Peptides
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Others
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Suc-Ala-Ala-Pro-Trp-Pna is a peptide. Suc-Ala-Ala-Pro-Trp-pNA can be used for the research of various biochemical.
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- HY-W713878
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Caspase
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Others
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Ac-VDVAD-pNA is a caspase-2 substrate. Ac-VDVAD-pNA can be used to test the activity of caspase-2 .
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- HY-P10084
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Caspase
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Others
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Ac-VAD-pNA is a caspase-1 substrate. Ac-VAD-pNA can be used to detect caspase-1 activity .
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- HY-P3938
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Peptides
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Others
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Suc-Ala-Ala-Pro-Gly-Pna is a peptide. Suc-Ala-Ala-Pro-Gly-pNA can be used for the research of various biochemical .
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- HY-P4464
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Ser/Thr Protease
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Cancer
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Ala-Phe-Pro-pNA is a chromogenic substrate of tripeptidyl peptidase. Ala-Phe-Pro-pNA can be used to test tripeptidyl peptidase activity .
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- HY-P4470
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Ser/Thr Protease
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Cancer
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Phe-Pro-Ala-pNA is a chromogenic substrate of tripeptidyl peptidase. Phe-Pro-Ala-pNA can be used to test tripeptidyl peptidase activity .
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- HY-P4477
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Ser/Thr Protease
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Others
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Suc-AAPR-pNA is a substrate of trypsin acyl-enzymes. Suc-AAPR-pNA can be used to test trypsin acyl-enzymes activity .
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- HY-P4518
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Ser/Thr Protease
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Others
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Z-Val-Gly-Arg-pNA is a chromogenic substrate for urokinase. Z-Val-Gly-Arg-pNA can be used for determination of urokinase activity .
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- HY-P2610
-
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Caspase
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Others
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Ac-VEID-pNA is an artificially synthesized peptide. Ac-VEID-pNA is utilized as substrate for caspase 6, that cleaves the lamin A at the cleavage site of VEID .
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- HY-P4658
-
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Peptides
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Others
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H-Val-Ala-pNA is a substrate for the dipeptide aminopeptidase (DPAPase) of Streptococcus bovis. H-Val-Ala-pNA can be used to measure the activity of the protease .
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- HY-P4202
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Suc-AEPF-pNA
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Biochemical Assay Reagents
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Others
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Suc-Ala-Glu-Pro-Phe-pNA (Suc-AEPF-pNA) is a chromogenic substrate for the peptidylprolyl isomerase Pin1. Suc-Ala-Glu-Pro-Phe-pNA can be used to evaluate the inhibitory effect of the target compound on Pin1, and catalytic activity of Pin1, etc .
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- HY-P4475
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-
- HY-P4202A
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Suc-AEPF-pNA TFA
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Biochemical Assay Reagents
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Others
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Suc-Ala-Glu-Pro-Phe-pNA (Suc-AEPF-pNA ) TFA is a chromogenic substrate for the peptidylprolyl isomerase Pin1. Suc-Ala-Glu-Pro-Phe-pNA TFA can be used to evaluate the inhibitory effect of the target compound on Pin1, and catalytic activity of Pin1, etc .
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- HY-P4453
-
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Caspase
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Cancer
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Boc-Ala-Ala-Asp-pNA is a chromogenic substrate of granzyme B. Boc-Ala-Ala-Asp-pNA can be used to test functional activity of granzyme B .
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- HY-P4517
-
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Peptides
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Others
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Z-Tyr-Lys-Arg-pNA is a chromogenic substrate. Z-Tyr-Lys-Arg-pNA can be used to detect the activity of subtilisin-type and yapsin-like proteases .
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- HY-P4516
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Peptides
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Cancer
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Z-Phe-Leu-Glu-pNA is a chromogenic substrate for glutamyl endopeptidases. Z-Phe-Leu-Glu-pNA has been used as a synthetic substrate in the study of proteolytic enzymes, including trypsin treatment, subtilisin and chymotrypsin. Z-Phe-Leu-Glu-pNA plays an important role in hormone disorders such as prostate cancer and breast cancer .
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- HY-P10161
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Peptides
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Others
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Ac-DMQD-pNA is a peptide substrate. Both of the recombinant CgCaspase-1 (rCgCaspase-1) and the C-terminus of CgCaspase-1 (rCgCaspase-1-C) exhibits similar caspase activity towards proteolytic substrate Ac-DMQD-pNA and Ac-DEVD-pNA (HY-P1006) .
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- HY-W011701
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- HY-P10005
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Peptides
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Cardiovascular Disease
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D-Val-Gly-Arg-pNA is a chromogenic substrate of TPA (tissue plasminogen activator). D-Val-Gly-Arg-pNA can be used to detect the amidolytic activity of TPA I and TPA II .
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- HY-P2091
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Caspase
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Inflammation/Immunology
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Ac-YVAD-pNA is a specific Caspase-1 substrate. Ac-YVAD-pNA can be used to detect Caspase-1 activity. Caspase-1 is a key mediator of inflammatory processes .
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- HY-P4515
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- HY-P4706
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- HY-P10083
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- HY-W011155
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- HY-P4361
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- HY-123275A
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S-2238 hydrochloride
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Fluorescent Dye
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Others
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H-D-Phe-Pip-Arg-pNA (S-2238) hydrochloride, a chromogenic substrate, is patterned after the N-terminal portion of the A alpha chain of fibrinogen, which is the natural substrate of thrombin. H-D-Phe-Pip-Arg-pNA hydrochloride is specific for thrombin and is used to measure antithrombin-heparin cofactor (AT-III). The AT-III assay using H-D-Phe-Pip-Arg-pNA hydrochloride is sensitive, accurate, and easy to perform .
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- HY-123275
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S-2238
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Fluorescent Dye
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Others
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H-D-Phe-Pip-Arg-pNA (S-2238), a chromogenic substrate, is patterned after the N-terminal portion of the A alpha chain of fibrinogen, which is the natural substrate of thrombin. H-D-Phe-Pip-Arg-pNA is specific for thrombin and is used to measure antithrombin-heparin cofactor (AT-III). The AT-III assay using H-D-Phe-Pip-Arg-pNA is sensitive, accurate, and easy to perform .
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- HY-123275C
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S-2238 dihydrochloride
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Fluorescent Dye
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Others
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H-D-Phe-Pip-Arg-pNA (S-2238) dihydrochloride, a chromogenic substrate, is patterned after the N-terminal portion of the A alpha chain of fibrinogen, which is the natural substrate of thrombin. H-D-Phe-Pip-Arg-pNA dihydrochloride is specific for thrombin and is used to measure antithrombin-heparin cofactor (AT-III). The AT-III assay using H-D-Phe-Pip-Arg-pNA dihydrochloride is sensitive, accurate, and easy to perform .
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-
- HY-123275B
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S-2238 acetate
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Fluorescent Dye
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Others
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H-D-Phe-Pip-Arg-pNA (S-2238) acetate, a chromogenic substrate, is patterned after the N-terminal portion of the A alpha chain of fibrinogen, which is the natural substrate of thrombin. H-D-Phe-Pip-Arg-pNA acetate is specific for thrombin and is used to measure antithrombin-heparin cofactor (AT-III). The AT-III assay using H-D-Phe-Pip-Arg-pNA acetate is sensitive, accurate, and easy to perform .
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- HY-P4465
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Peptides
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Others
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Gly-Arg-pNA is a fluorogenic substrate for the measurement of protease activity. Gly-Arg-pNA undergoes hydrolysis and releases the fluorescent product p-nitroaniline. p-nitroaniline is in a fluorescent state under ultraviolet light irradiation and can emit a fluorescent signal .
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- HY-P0021A
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Spectrozyme PCa; Chromozym Pca diacetate
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Fluorescent Dye
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Others
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D-Lys(Z)-Pro-Arg-pNA diacetate (Spectrozyme PCa) is a chromogenic substrate.
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- HY-P5376
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Peptides
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Others
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MeOSuc-Arg-Pro-Tyr-pNA is a biological active peptide. (chymotrypsin substrate)
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- HY-P4343
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Peptides
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Others
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Lys(Abz)-Pro-Pro-pNA is a fluorescent peptide substrate of PepP .
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- HY-P4489
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Peptides
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Others
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Suc-AAPM-pNA is a sensitive substrate for the determination of human pancreatic elastase activity .
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- HY-P6027
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Peptides
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Others
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H-D-CHA-Ala-Arg-pNA is a chromogenic substrate for the amidolytic assay .
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- HY-137409
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Peptides
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Others
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Suc-AAA-pNA?is the substrate of analysis of the reversible inhibition of porcine pancreatic elastase (PPE) .
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- HY-P4498
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Peptides
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Others
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Z-Ala-Pro-pNA is an endopeptidase substrate and can be used to detect the activity of this enzyme .
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- HY-P4772
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Peptides
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Others
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Me-CO-Lys(Cbo)-Gly-Arg-pNA is a substrate for C1 esterase .
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- HY-P4402
-
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Peptides
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Others
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D-Ile-Phe-Lys-pNA is a highly specific substrate for human plasmin .
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- HY-P1006
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Caspase
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Others
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Ac-DEVD-pNA is a colorimetric substrate for caspase-3 (CPP32) and related cysteine proteases.
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- HY-137186
-
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Proteasome
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Others
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Suc-Gly-Gly-Phe-pNA is the chymotrypsin substrate with an Km value of 1.6 mM .
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- HY-P3936
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Fluorescent Dye
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Others
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Endotoxin Substrate (Boc-LGR-pNA) is a chromogenic substrate can be used in quantitative assays of endotoxin .
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- HY-P4468
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- HY-P4500
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Cathepsin
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Others
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Z-Arg-Arg-pNA is a substrate for cathepsin B and can be used to detect this enzyme activity .
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- HY-P0021
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Chromozym Pca
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Fluorescent Dye
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Others
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D-Lys(Z)-Pro-Arg-pNA (Chromozym Pca) is a luminescent substrate of activated protein C (APC).
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- HY-P3126
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Factor Xa
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Others
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Suc-Ile-Glu(γ-pip)-Gly-Arg-pNA hydrochloride is a factor Xa specific chromogenic substrate .
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- HY-P4484
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Peptides
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Others
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Suc-AAPK-pNA is a chromogenic substrate for the determination of serine/threonine kinase activity and enzyme kinetic parameters .
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- HY-P4490
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- HY-P4494
-
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Cathepsin
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Others
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Suc-Val-Pro-Phe-pNA is a substrate for cathepsin G and can be used to detect the activity of this enzyme .
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- HY-138109
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Peptides
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Others
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D-Pro-Phe-Arg-pNA hydrochloride is the substrate for thrombin-like enzyme, with Km of 50.7 μM .
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- HY-P4582
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Suc-FAAF-pNA
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Peptides
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Others
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Suc-Phe-Ala-Ala-Phe-pNA (Suc-FAAF-pNA) is a synthetic polypeptide that can serve as a substrate for the protease from Aeribacillus pallidus VP3 (SPVP), the serine alkaline protease from Caldicoprobacter guelmensis (SAPCG) strain D2C22 T, the alcalase ultra 2.5 L and the thermolsyin type X .
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- HY-P2685
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Fluorescent Dye
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Others
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MeOSuc-Ala-Ala-Pro-Val-pNA is a sensitive fluorogenic substrate of human leukocyte and porcine pancreatic elastase .
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- HY-P4496
-
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Peptides
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Others
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Tos-Gly-Pro-Lys-pNA is a substrate for the serine protease ALP and can be used to measure the activity of this enzyme .
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- HY-P3794
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Peptides
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Infection
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Glu-Ala-Leu-Phe-Gln-pNA is a Chiba virus 3C-like protease (CVP) substrate .
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- HY-P10145
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Peptides
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Others
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Ac-LEVD-pNA is a chromogenic substrate for caspase-4 and can be used to detect caspase-4 activity .
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- HY-P10236
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Caspase
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Others
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Ac-WEHD-pNA is a colorimetric substrate for caspase 1, 4, 5 and 14, which is utilized to measure the caspase activity .
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- HY-P4491
-
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Peptides
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Others
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Suc-Leu-Leu-Val-Tyr-pNA is a chymotrypsin-like chromogenic substrate that can be used to detect chymotrypsin enzymatic activity .
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- HY-126785
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Colorimetric Elastase Substrate
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Elastase
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Others
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Suc-AAP-Abu-pNA (Colorimetric Elastase Substrate) is a specific substrate for pancreatic elastase (Km = 100 μM; Kcat/Km = 35,300 s -1 M -1 for rat pancreatic elastase; Km = 30 μM; Kcat/Km = 351,000 s -1 M -1 for porcine pancreatic elastase). Suc-AAP-Abu-pNA also promotes OPC migration .
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- HY-P4576
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Factor Xa
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Others
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Methoxycarbonyl-D-Nle-Gly-Arg-pNA is a synthetic trypsin that can serve as a substrate for coagulation factors IXa (FIXa) and Xa (FXa) .
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- HY-P4462
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Peptides
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Others
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D-Leu-Thr-Arg-pNA is a substrate for γ-Tryptase, and can be used to measure the effects of small molecule inhibitors on γ-Tryptase activity .
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- HY-P3236
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Ac-IEPD-pNA
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Peptides
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Cancer
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N-Acetyl-Ile-Glu-Pro-Asp-p-nitroanilide (Ac-IEPD-pNA) is a granzyme B substrate that allows accurate measurement of granzyme B activity .
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- HY-114150
-
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Peptides
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Others
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D-Val-Leu-Arg-pNA is a glandular kininoreleasing enzyme substrate that also acts as a substrate for tissue-type plasminogen activator (t-PA) with no apparent affinity for fibrin .
|
- HY-P4039
-
|
HCV Protease
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Infection
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Ac-EEVVAC-pNA is a chromogenic substrate for a continuous spectrophotometric assay of HCV NS3 protease. The sequence EEVVAC is derived from the 5A-5B cleavage junction of the HCV polyprotein .
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- HY-P4254
-
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Peptides
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Others
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H-Gly-Glu-pNA is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .
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- HY-P5027
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Peptides
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Others
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Cbz-Lys-Arg-pNA is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .
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- HY-P4921
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Peptides
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Others
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Suc-Gly-Pro-pNA is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .
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- HY-120833
-
|
Caspase
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Others
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Ac-Ile-Glu-Thr-Asp-pNA is a substrate for caspase-8. Caspase-8 binds to and cleaves the Ile-Glu-Thr-Asp (IETD) peptide sequence to release p-nitroalinide, which can be quantified by colorimetric detection at 405 nm as a measure of enzyme activity .
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- HY-P3480
-
|
Fluorescent Dye
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Others
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H-Trp-Phe-Tyr-Ser(PO3H2)-Pro-Arg-pNA is a chromogenic substrate for Pin1. Pin1 is an essential and conserved mitotic peptidyl-prolyl isomerase, and can recognize the phosphoserine-proline bonds present in mitotic phosphoproteins .
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Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
Cat. No. |
Product Name |
Application |
Reactivity |
-
- HY-P82103
-
BAP; Bap37; BCAP 37; D prohibitin; p22; Phb2; PNAs 141; Prohibitin 2
|
WB, IHC-F, IHC-P, ICC/IF
|
Human, Mouse, Rat |
-
- HY-P82407
-
ARC34; PRO2446; p34-Arc; PNAs-139
|
WB, IHC-F, IHC-P, ICC/IF, IP
|
Human, Mouse, Rat |
Cat. No. |
Product Name |
|
Classification |
-
- HY-151778
-
|
|
Azide
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Fmoc-Abg(N3)-OH is a click chemistry reagent containing an azide group. Fmoc-Abg(N3)-OH has the potential to synthesize peptide nucleic acids (PNA) and peptoids.
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-
- HY-151738
-
|
|
Azide
|
Fmoc-Aeg(N3)-OH is a click chemistry reagent containing an Azide. Alkylating the Nitrogen of an amide bond results in peptoid structures, which leads to conformational restrains, like N-methylation and allows backbone derivatisation. Altering cytotoxicity, bacterial cell selectivity and receptor pharmacology through formation of peptoid derivatives have been published for Cilengitide, Piscidin 1, and MC3, MC4 and MC5 receptor agonist. This building block enables design of macrocycles through intermolecular crosslinking or backbone stabilization through intermolecular ring-closure. This compound is a potential building block for the construction of (customized) peptide nucleic acids (PNAs) and for peptoid synthesis . Fmoc-Aeg(N3)-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-151828
-
|
|
Azide
|
N3-Gly-Aeg(Fmoc)-OH is a click chemistry reagent containing an azide group. PNA building-block that can be further modified using Click-chemistry .
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