Suc-AAPA-pNA
Based on 1 publication(s) in Google Scholar
Suc-AAPA-pNA is a substrate for chymotrypsin A and elastase. Suc-AAPA-pNA can be used for enzyme activity assay.
For research use only. We do not sell to patients.
- Purity: 98.19%
- CAS No.: 72682-69-0
- Formula: C24H32N6O9
- Molecular Weight:548.55
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Storage:
Sealed storage, away from moisture.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
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Publications Citing Use of MedChemExpress (MCE) Suc-AAPA-pNA
More
Biological Activity
Suc-AAPA-pna serves as a reference substrate for bovine chymotrypsin A[1].
suc-AAPA-pNA can be used as a tool to develop and screen engineered proteases that can efficiently and specifically cleave small molecule substrates[3].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 72682-69-0
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Appearance Solid
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Molecular Weight 548.55
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Formula C24H32N6O9
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Color White to off-white
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Sequence
{Suc-Ala}-Ala-Pro-{Ala-pNA}
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Sequence Shortening
{Suc-Ala}-AP-{Ala-pNA}
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Sealed storage, away from moisture
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Publications (1)
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Journal Impact Factor
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Most Recent
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Int J Biol Macromol
Dynamic catalytic domain plasticity governs substrate specificity in industrial serine proteases: Structural and functional implications. [Abstract]2025 Oct 17;331(Pt 1):148374. PMID: 41110577
Purity & Documentation
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Data Sheet (270 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
[1]. Qasim MA, et al. Thermodynamic criterion for the conformation of P1 residues of substrates and of inhibitors in complexes with serine proteinases. Biochemistry. 1999;38(22):7142-7150. [Content Brief]
[2]. Fu Z, et al. Asp-ase Activity of the Opossum Granzyme B Supports the Role of Granzyme B as Part of Anti-Viral Immunity Already during Early Mammalian Evolution. PLoS One. 2016;11(5):e0154886. Published 2016 May 6. [Content Brief]
[3]. Qi D, et al. Generation of new enzymes via covalent modification of existing proteins. Chem Rev. 2001 Oct;101(10):3081-111. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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