Methoxycarbonyl-D-Nle-Gly-Arg-pNA
Methoxycarbonyl-D-Nle-Gly-Arg-pNA is a synthetic trypsin that can serve as a substrate for coagulation factors IXa (FIXa) and Xa (FXa).
For research use only. We do not sell to patients.
- CAS No.: 104186-68-7
- Formula: C22H34N8O7
- Molecular Weight:522.55
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
IC50 & Target
Factors IXa[3]
Chemical Information
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CAS No. 104186-68-7
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Molecular Weight 522.55
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Formula C22H34N8O7
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Sequence
Methoxycarbonyl-D-Nle-Gly-Arg-pNA
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Sequence Shortening
Methoxycarbonyl-{d-Nle}-GR-pNA
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Hopfner KP, et al. New enzyme lineages by subdomain shuffling. Proc Natl Acad Sci U S A. 1998 Aug 18;95(17):9813-8. [Content Brief]
[2]. Hopfner KP, et al. Converting blood coagulation factor IXa into factor Xa: dramatic increase in amidolytic activity identifies important active site determinants. EMBO J. 1997 Nov 17;16(22):6626-35. [Content Brief]
[3]. Sturzebecher J, et al. Dramatic enhancement of the catalytic activity of coagulation factor IXa by alcohols. FEBS Lett. 1997 Jul 28;412(2):295-300. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)