104186-68-7
104186-68-7
Chemical Structure
Methoxycarbonyl-D-Nle-Gly-Arg-pNA
- CAS No.: 104186-68-7
- Formula:C22H34N8O7
- Molecular Weight:522.55
InChIKey: XEXULFKIPLAHKX-SJORKVTESA-N
SMILES: [O-][N+](C(C=C1)=CC=C1NC([C@H](CCCNC(N)=N)NC(CNC([C@@H](CCCC)NC(OC)=O)=O)=O)=O)=O
Biological Activity: Methoxycarbonyl-D-Nle-Gly-Arg-pNA is a synthetic trypsin that can serve as a substrate for coagulation factors IXa (FIXa) and Xa (FXa)[1][2][3].
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Methoxycarbonyl-D-Nle-Gly-Arg-pNA | Methoxycarbonyl-D-Nle-Gly-Arg-pNA is a synthetic trypsin that can serve as a substrate for coagulation factors IXa (FIXa) and Xa (FXa). | |||||||||||||||||||||
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References
- [1]. Hopfner KP, et al. New enzyme lineages by subdomain shuffling. Proc Natl Acad Sci U S A. 1998 Aug 18;95(17):9813-8. [Content Brief]
- [2]. Hopfner KP, et al. Converting blood coagulation factor IXa into factor Xa: dramatic increase in amidolytic activity identifies important active site determinants. EMBO J. 1997 Nov 17;16(22):6626-35. [Content Brief]
- [3]. Sturzebecher J, et al. Dramatic enhancement of the catalytic activity of coagulation factor IXa by alcohols. FEBS Lett. 1997 Jul 28;412(2):295-300. [Content Brief]
Keywords
