84 Results for "

Small molecule peptides

" in MedChemExpress (MCE) Product Catalog:
Products (84)

84 Results for "Small molecule peptides" in MCE Product Catalog:

45
45 Publications Verification
Cat. No.: HY-D0819
CAS No.: 146368-14-1
Synonyms: Cy5 NHS Ester; Sulfo-Cyanine5 Succinimidyl Ester
Cy5-SE (Cy5 NHS Ester) is a reactive dye for the labeling of amino-groups in peptides, proteins, and oligonucleotides. This dye requires small amount of organic co-solvent (such as DMF or DMSO) to be used in labeling reaction. This reagent is ideal for very cost-efficient labeling of soluble proteins, as well as all kinds of peptides and oligonucleotides. This reagent also works well in organic solvents for small molecule labeling. Excitation (nm):649, Emission (nm): 670.
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5
5 Cited Publications
Cat. No.: HY-D0098
CAS No.: 75350-46-8
Synonyms: N-(5-Fluoresceinyl)maleimide
Fluorescein-5-maleimide (N-(5-Fluoresceinyl)maleimide) is a fluorescent dye. Fluorescein-5-maleimide can be used to detect the redox state of thiols in eukaryotic cells. Fluorescein-5-maleimide can label peptides and is used to detect negatively charged nanoparticles. Fluorescein-5-maleimide can also label actin to explore its interaction with cardiac myosin-binding protein C (cMyBP-C), which helps in developing small molecule modulators for heart failure. Fluorescein-5-maleimide can screen mutant proteins that contain cysteine residues. The excitation wavelength of Fluorescein-5-maleimide is 494 nm, and the emission wavelength is 519 nm .
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3
3 Cited Publications
Cat. No.: HY-113225B
CAS No.: 103192-46-7
Synonyms: GTP tritris solution (100 mM)
Research Areas:  

Cancer

Guanosine triphosphate tritris (GTP tritris) (100 mM) serves as a vital enhancer of myogenic cell differentiation and plays a critical role in modulating miRNA-myogenic regulator factors. It also facilitates the release of exosomes enriched with guanosine and guanosine-derived molecules, and is regarded as an activated precursor for RNA synthesis. In mitochondrial function, GTP participates in the import of proteins into the matrix, which is essential for various regulated pathways, and is involved in initiating peptide synthesis through the binding of formylmethionyl-tRNA to the ribosome, as well as polypeptide chain elongation. Additionally, GTP acts as a phosphate and pyrophosphate carrier that channels chemical energy into specific biosynthetic pathways. It activates signal transducing G proteins that regulate cellular processes such as proliferation and differentiation, and its hydrolysis by small GTPases, including Ras and Rho, is integral to both proliferation and apoptosis. Furthermore, the small GTPase Rab is instrumental in vesicle docking, fusion, and formation. Beyond signal transduction, GTP is an energy-rich precursor in the enzymatic biosynthesis of DNA and RNA.
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2
2 Cited Publications
Cat. No.: HY-16664
CAS No.: 431979-47-4
Research Areas:  

Cancer

SJ-172550 is a small molecule inhibitor of MDMX; competes for the wild type p53 peptide binding to MDMX with an EC50 of 5 μM.
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1
1 Cited Publications
Cat. No.: HY-N0630
CAS No.: 64421-28-9
Shanzhiside methy lester is isolated from lamiophlomis rotata. Shanzhiside methyl ester is a small molecule glucagon-like peptide-1 (GLP-1) receptor agonist and has the ability to induce anti-allodynic tolerance .
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1
1 Cited Publications
Cat. No.: HY-148263
Purity:  ≥98.0%
Target:  

Fluorescent Dye

Research Areas:  

Cancer

Biotin-PEG2000-Thiol is an active compound. Biotin-PEG2000-Thiol is pegylated by binding to streptavidin or antibiotin with high affinity and specificity. Biotin-PEG2000-Thiol can modify biomolecules, proteins, peptides and other small molecule materials. Biotin-PEG2000-Thiol is widely used in the research of agent release and nano new materials .
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Cat. No.: HY-P2962
CAS No.: 80146-85-6
Synonyms: TG
Transglutaminase, Streptoverticillium mobaraense (TG) is an enzyme that forms cross-links between protein molecules. Transglutaminase, Streptoverticillium mobaraense attaches proteins and peptides to small molecules, polymers, surfaces, DNA and other proteins. Transglutaminase, Streptoverticillium mobaraense is widely used in food applications in the meat, fish, dairy and baking industries .
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Cat. No.: HY-123617
CAS No.: 2100285-41-2
Purity:  99.30%
AZ8838 is a potent, competitive, allosteric, orally active non-peptide small molecule antagonist of PAR2 with a pKi of 6.4 for hPAR2 .
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Cat. No.: HY-D1872
CAS No.: 956579-01-4
800CW NHS ester is a near-infrared fluorescent dye active ester that can conjugate with amine-containing small molecules, antibodies, peptides, and other substances to form fluorescent conjugates. 800CW NHS ester exhibits high fluorescence quantum yield and low non-specific binding properties. 800CW NHS ester can be used in biomedical research such as microbial infection imaging, tumor imaging, and biochemical detection .
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Cat. No.: HY-13631EG
CAS No.: 1599440-13-7
Synonyms: MC-GGFG-DXD (GMP)
Deruxtecan (GMP) (MC-GGFG-DXD (GMP)) is Deruxtecan (HY-13631E) in GMP grade. GMP-grade small molecules can be used as auxiliary reagents in cell therapy. Deruxtecan is an ADC drug-linker conjugate composed of an DX-8951 derivative (DXd) and a maleimide-GGFG peptide linker, used for synthesizing Trastuzumab deruxtecan (HY-138298A) and Patritumab deruxtecan (HY-P99813) .
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Cat. No.: HY-P10739
CAS No.: 1021155-39-4
Target:  

Exosomes Collagen

Research Areas:  

Inflammation/Immunology

WYRGRL is a selective, high-affinity collagen type II-binding peptide with a IC50 of 140 nM. Collagen type II is the most abundant and specific structural protein in the extracellular matrix of articular cartilage. WYRGRL can precisely target small-molecule compounds such as Dexamethasone (HY-14648) and nanocarrier-engineered exosomes to cartilage, significantly enhancing their therapeutic effects on osteoarthritis .
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Cat. No.: HY-103080
CAS No.: 1586787-08-7
Purity:  99.89%
Target:  

Apelin Receptor (APJ)

Research Areas:  

Cardiovascular Disease

CMF019 is an orally active, potent and small molecule agonist at Apelin receptor (APJ) with G protein bias. CMF019 binds to APJ with pKi values of 8.58, 8.49 and 8.71 for human, rat, and mouse, respectively. CMF019 mimics the beneficial cardiovascular actions of apelin in rodents . Apelin receptor (APJ) is a G protein-coupled receptor (GPCR) activated by the endogenous peptide apelin. CMF019 is promising for research of chronic diseases, such as, pulmonary arterial hypertension .
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Cat. No.: HY-P10409
CAS No.: 1191923-93-9
Synonyms: Small humanin-like peptide 2
SHLP2 (Small humanin-like peptide 2) is a small molecule peptide encoded by mitochondrial DNA, belonging to mitochondria derived peptide. SHLP2 has the activity of regulating apoptosis and inhibits cell death. SHLP2 binds to mitochondrial complex 1. SHLP2 improves mitochondrial metabolism by increasing respiration and biogenesis, reducing ROS, and decreasing mtDNA oxidation. SHLP2 also regulated energy homeostasis through the activation of hypothalamic neurons. SHLP2 can be used in the study of diseases related to mitochondrial dysfunction and anti-aging diseases, such as age-related macular degeneration and Parkinson’s disease .
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Cat. No.: HY-164166
CAS No.: 2749824-37-9
Research Areas:  

Others

Fmoc-Sar-Sar-Sar-OH is a small molecule polypeptide composed of sarcosine residues, in which the N-terminus of the peptide chain is protected by Fmoc. Fmoc-Sar-Sar-Sar-OH can be used for peptide synthesis or synthesis of agent-peptide ligand conjugates .
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Cat. No.: HY-78985
CAS No.: 554-95-0
Synonyms: Trimesic acid
Benzene-1,3,5-tricarboxylic acid (Trimesic acid) is a rigid planar small-molecule scaffold and crosslinker. Benzene-1,3,5-tricarboxylic acid induces bicyclic peptides to adopt a planar conformation, so as to maximize surface area and bind to the flat protein surfaces involved in protein-protein interactions. Benzene-1,3,5-tricarboxylic acid forms ionic crosslinks, hydrogen bonds and π-π bonds with chitosan, thereby constructing a hydrogel network. Benzene-1,3,5-tricarboxylic acid endows chitosan hydrogel systems with specific mechanical properties, enabling sustained release of cancer therapeutic drugs including 5-Fluorouracil (HY-90006) .
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Cat. No.: HY-P3432
CAS No.: 2035480-78-3
Research Areas:  

Others

DfTat is a dimer of the prototypical cell-penetrating peptide TAT. DfTat can deliver small molecules, peptides and proteins into live cells with a particularly high efficiency. DfTat labeled with the rhodamine can be used as a tracer for easy detection .
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Cat. No.: HY-P1805
CAS No.: 104041-80-7
Target:  

Calmodulin

Research Areas:  

Neurological Disease

Calmodulin Binding Peptide 1 is a high-affinity (pM) CaM-binding peptide derived from smooth muscle myosin light chain kinase (MLCK peptide). The interface of the complex formed by Calmodulin Binding Peptide 1 and Ca 2+-CaM can be specifically bound by small-molecule inhibitors, serving as a key target for selective regulation of smooth muscle contraction and development of anti-CaM drugs .
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Cat. No.: HY-157269
CAS No.: 1069110-72-0
Target:  

Hapten

Research Areas:  

Inflammation/Immunology

J10-1 is a hapten small molecule. J10-1 accelerates peptide exchange in MHC class II molecules in an HLA-DM-independent manner, and its effect is not affected by the polymorphism of the P1 pocket of MHC class II molecules. J10-1 enhances the processes of peptide dissociation, peptide binding and peptide association of MHC class II molecules on the surface of B cells. J10-1 can be used for research on immunoregulation .
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Cat. No.: HY-P1350
CAS No.: 38579-27-0
Target:  

Bacterial

Research Areas:  

Infection

H-Lys-Trp-Lys-OH is a small molecule peptide which displays antibacterial and antiviral activities extracted from patent CN 104072579 A, Compound AMP12.
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Cat. No.: HY-DY1063
CAS No.: 146368-14-1
Cy5-SE (Cy5 NHS Ester) (solution) is a reactive dye for the labeling of amino-groups in peptides, proteins, and oligonucleotides. This dye requires small amount of organic co-solvent (such as DMF or DMSO) to be used in labeling reaction. This reagent is ideal for very cost-efficient labeling of soluble proteins, as well as all kinds of peptides and oligonucleotides. This reagent also works well in organic solvents for small molecule labeling. Excitation (nm) :649, Emission (nm) : 670.
Solvent and concentration: DMSO: 10 mM
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