Glucose-PEG5000-NHS
Glucose-PEG5000-NHS is a conjugate composed of glucose, PEG chains, and an active ester (NHS). Glucose-PEG5000-NHS combines the targeted recognition capabilities of glucose with the ability to rapidly covalently react with molecules containing primary amines (such as proteins, peptides, and amino-modified small molecules) to form stable amide bonds in an NHS ester. This allows for applications such as constructing targeted drug delivery systems and modifying nanoparticles.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
The Glucose-PEG-NHS structure comprises three key components that work synergistically:
Glucose: Specifically recognizes and binds to glucose transporters (such as GLUT1) highly expressed on the surface of various cells (especially tumor cells), enabling receptor-mediated active targeted delivery.
PEG Chain: Acts as a hydrophilic spacer, forming a hydration layer on the particle surface, reducing non-specific adsorption and immune system clearance, thus prolonging the carrier's circulation time in vivo.
NHS: Serves as a reaction interface, reacting efficiently with molecules containing primary amino groups (such as antibodies and peptides) under mild conditions to form stable covalent bonds.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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SMILES
OC1O[C@H]([C@@H]([C@H]([C@@H]1NC(OCCOC(ON2C(CCC2=O)=O)=O)=O)O)O)CO.[n]
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)