800CW NHS ester 

800CW NHS ester is a near-infrared fluorescent dye active ester that can conjugate with amine-containing small molecules, antibodies, peptides, and other substances to form fluorescent conjugates. 800CW NHS ester exhibits high fluorescence quantum yield and low non-specific binding properties. 800CW NHS ester can be used in biomedical research such as microbial infection imaging, tumor imaging, and biochemical detection^[1][2].

800CW NHS ester (5 days) forms a dual-labeled conjugate with Vanco-FL after 5 days of incubation under established optimized conditions, targeting the free secondary amine of Vanco-FL^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

1166.20

C₅₀H₅₄N₃Na₃O₁₇S₄

956579-01-4

Solid

Brown to breen

O=S(C(C=C1C2(C)C)=CC=C1N(/C2=C/C=C3CCCC(/C=C/C4=[N+](CCCCS(=O)([O-])=O)C5=C(C=C(C=C5)S(=O)(O[Na])=O)C4(C)C)=C\3OC6=CC=C(C=C6)S(=O)(O[Na])=O)CCCCCC(ON7C(CCC7=O)=O)=O)(O[Na])=O

Room temperature in continental US; may vary elsewhere.

-20°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

• [1]. Kovar J, et al. Near infrared probes for biochemical, cellular, and whole animal analysis of disease processes//Reporters, Markers, Dyes, Nanoparticles, and Molecular Probes for Biomedical Applications. SPIE, 2009, 7190: 71-78.

  [2]. Reeßing F, et al. A Facile and Reproducible Synthesis of Near-Infrared Fluorescent Conjugates with Small Targeting Molecules for Microbial Infection Imaging. ACS Omega. 2020;5(35):22071-22080. Published 2020 Aug 26.  [Content Brief]