2. Signaling Pathways
  3. Immunology/Inflammation
  4. Hapten

Hapten

Hapten, also known as incomplete antigen, refers to simple small molecule antigen that only has immune response specificity but no immunogenicity, such as certain polysaccharides, lipids, and drugs. Haptens are small molecules that elicit an immune response only when attached to a large carrier such as a protein; the carrier may be one that also does not elicit an immune response by itself. Attaching of haptens to a carrier molecule lead to a complete antigen. Haptens have been used to study allergic contact dermatitis (ACD) and the mechanisms of inflammatory bowel disease (IBD) to induce autoimmune-like responses.

Hapten Related Products (28):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-30272
    Monobenzone
    		99.93%
    Monobenzone is a potent skin depigmenting agent. Monobenzone induces depigmentation and exhibits good potential for vitiligo research. Monobenzone is a potent inhibitor of RNR (Ribonucleotide reductase) enzyme activity by targeting RRM2 (a regulatory small subunit M2 of RNR) protein, and thus has significant anti-leukemia efficacy in vitro and in vivo. Monobenzone inhibits acute myeloid leukemia (AML) cells proliferation and DNA synthesis, induces cell cycle arrest, and Apoptosis .
    Monobenzone
  • HY-157269
    J10-1
    		99.92%
    J10-1 is a hapten small molecule. J10-1 accelerates peptide exchange in MHC class II molecules in an HLA-DM-independent manner, and its effect is not affected by the polymorphism of the P1 pocket of MHC class II molecules. J10-1 enhances the processes of peptide dissociation, peptide binding and peptide association of MHC class II molecules on the surface of B cells. J10-1 can be used for research on immunoregulation.
    J10-1
  • HY-155446
    di-DTPA-LTL
    di-DTPA-LTL is a bivalent hapten based on tyrosine-containing polypeptide design. di-DTPA-LTL has good hydrophilia and biological distribution. di-DTPA-LTL is labeled with 111In (indium) and 131I (iodine). di-DTPA-LTL achieves tumor radioimmunoimaging in primary colorectal cancer patients with CEA by injecting a fixed low dose (5 mg) of bispecific antibody (anti-CEA x, anti-DTPA) and di-DTPA antigen peptide (labeled 111In) into the patients.
    di-DTPA-LTL
  • HY-155445
    di-DTPA TL
    di-DTPA TL is a hydrophilic bivalent DTPA hapten that can be used for tumor research.
    di-DTPA TL
  • HY-155469
    IMP 241
    IMP 241 is a di-HSG bivalent hapten.
    IMP 241
  • HY-161005
    TETS-Methyl benzoate
    TETS-Methyl benzoate(compound 2j) is a haptendirectly conjugated to the carrier protein via carboxylic acid function using the standard activated ester method.
    TETS-Methyl benzoate
  • HY-163025
    Cyanazine-3-mercaptopropanoic acid
    Cyanazine-3-mercaptopropanoic acid (compound 6), a coating hapten, is a stable carrier-hapten complex. Polyclonal antibody obtained were with a high titer, with the IC50 of 10.2 ng/mL for Cyanazine-3-mercaptopropanoic acid.
    Cyanazine-3-mercaptopropanoic acid
  • HY-149737
    FXn
    FXn is a hapten that can be used for the generation of mAbs. FXh is activated by incubation with N, N′-disuccinimidyl carbonate, and Et3N in acetonitrile at 0 °C. FXn is covalently linked to the protein via N-hydroxy succinimidyl ester.
    FXn
  • HY-155455
    Dicamba-(CH2)5-acid
    Hapten Dca is an immunizing hapten. Hapten Dca is activated by a solution of N, N′-disuccinimidyl carbonate. Hapten Dca with a carboxyl functional group is conjugated to proteins.
    Dicamba-(CH2)5-acid
  • HY-149754
    Ursodeoxycholic acid 7-N-acetylglucosaminide
    Ursodeoxycholic acid 7-N-acetylglucosaminide is an immunizing and heterologous hapten.
    Ursodeoxycholic acid 7-N-acetylglucosaminide
  • HY-163014
    Dicamba 1-azidopropane
    Dicamba 1-azidopropane (DCn) is an immunizing and heterologous hapten. Dicamba 1-azidopropane can be used to generate monoclonal antibodies specific of Dicamba.
    Dicamba 1-azidopropane
  • HY-155447
    AG3.0
    AG3.0 is a symmetric di-HSG bivalent hapten. AG3.0 can be used for the research of pretargeted radioimmunotherapy.
    AG3.0
  • HY-157282
    Photolumazine I
    Photolumazine I(PLI) is a vitamin B-based hapten.Photolumazine Icanactivates Mucosal-associated Invariant T clones.
    Photolumazine I
  • HY-149753
    Methylthiomcresol-succinaldehydic acid
    Methylthiomcresol-succinaldehydic acid is a fenthion hapten that can be used for immunoreagent production (protein conjugates and polyclonal antibodies).
    Methylthiomcresol-succinaldehydic acid
  • HY-155495
    (±)-Bupropion-(CH2)3-OH hydrochloride
    (±)-Bupropion-(CH2)3-OH hydrochloride (compound 3) is a hapten useful in the radioimmunoassay of Bupropion (HY-B0403).
    (±)-Bupropion-(CH2)3-OH hydrochloride
  • HY-157262
    Methyl isonicotinate-(CH2)2-COOH
    Methyl isonicotinate-(CH2)2-COOH (hapten 2b) is a hapten that can be activated with NHS and DCC. Methyl isonicotinate-(CH2)2-COOH has more immunogenicity and hydrophobicity.
    Methyl isonicotinate-(CH2)2-COOH
  • HY-163013
    Dicamba-5-hydroxypentanoic acid
    Dicamba-5-hydroxypentanoic acid (DCo), synthesized from commercially available 5-hydroxy-dicamba, is an immunizing and heterologous hapten. Dicamba-5-hydroxypentanoic acid (DCo) is chemoselectively activated using one equivalent of DSC (N,N- disuccinimidyl carbonate).
    Dicamba-5-hydroxypentanoic acid
  • HY-157202
    Zeoh
    Zeoh, an immunizing and heterologous hapten, contains one unprotected OH group at a distal position.
    Zeoh
  • HY-163023
    Atrazine-acetic acid
    Atrazine-acetic acid is an immunizing and heterologous hapten.
    Atrazine-acetic acid
  • HY-149752
    Methylthiomcresol-C1-benzoic acid
    Methylthiomcresol-C1-benzoic acid is a fenthion hapten that can be used for immunoreagent production (protein conjugates and polyclonal antibodies).
    Methylthiomcresol-C1-benzoic acid