SM6.1-azide
Based on 1 Customer Validation
SM6.1-azide is a reactant containing an azide group, which can be used in copper-catalyzed azide-alkyne cycloaddition click reactions. SM6.1-azide facilitates the synthesis of trivalent targeted ligand-siRNA conjugates. SM6.1-azide undergoes click chemistry reactions with alkyne-modified oligonucleotides.
For research use only. We do not sell to patients.
- Purity : 99.50%
- CAS No.: 2320477-40-3
- Formula: C41H51N7O9
- Molecular Weight:785.89
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Storage:Pure form -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
Description
In Vitro
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2320477-40-3
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Appearance Solid-Liquid Mixture
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Molecular Weight 785.89
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Formula C41H51N7O9
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Color White to off-white
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SMILES
[N-]=[N+]=NCCOCCOCCOCCOCCOC1=CC=C(C2=CC=C(C=C2)[C@H](CC(O)=O)NC(CNC(CCCNC3=CC(C)=CC=N3)=O)=O)C4=C1C=CC=C4
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Pure form -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
In Vitro:
DMSO : 100 mg/mL (127.24 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Working solution concentration: 0.22 mg/mL
Purity & Documentation
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Data Sheet (270 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.2724 mL | 6.3622 mL | 12.7244 mL | 31.8111 mL |
| 5 mM | 0.2545 mL | 1.2724 mL | 2.5449 mL | 6.3622 mL | |
| 10 mM | 0.1272 mL | 0.6362 mL | 1.2724 mL | 3.1811 mL | |
| 15 mM | 0.0848 mL | 0.4241 mL | 0.8483 mL | 2.1207 mL | |
| 20 mM | 0.0636 mL | 0.3181 mL | 0.6362 mL | 1.5906 mL | |
| 25 mM | 0.0509 mL | 0.2545 mL | 0.5090 mL | 1.2724 mL | |
| 30 mM | 0.0424 mL | 0.2121 mL | 0.4241 mL | 1.0604 mL | |
| 40 mM | 0.0318 mL | 0.1591 mL | 0.3181 mL | 0.7953 mL | |
| 50 mM | 0.0254 mL | 0.1272 mL | 0.2545 mL | 0.6362 mL | |
| 60 mM | 0.0212 mL | 0.1060 mL | 0.2121 mL | 0.5302 mL | |
| 80 mM | 0.0159 mL | 0.0795 mL | 0.1591 mL | 0.3976 mL | |
| 100 mM | 0.0127 mL | 0.0636 mL | 0.1272 mL | 0.3181 mL |