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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
97 Results for "
asymmetric
" in MedChemExpress (MCE) Product Catalog:
Products (97)
97 Results for "asymmetric" in MCE Product Catalog:
5
5 Cited Publications
Synonyms: NG,NG-Dimethylarginine
Category:
Cardiovascular Disease Human Gut Microbiota Metabolites Microorganisms Ketones, Aldehydes, Acids Endogenous metabolite Disease Research Fields
Target:
3
3 Cited Publications
Target:
Research Areas:
UCB-9260, an orally active compound, inhibits TNF signaling by stabilising an asymmetric form of the trimer. UCB-9260 is selective for TNF over other superfamily members, and binds TNF with a similar Kd of 13 nM .
2
Category:
Infection Alkaloids Piperidine Alkaloids Cinchona officinalis Linn. Rubiaceae Quinoline Alkaloids Plants Disease Research Fields
Target:
1
1 Cited Publications
Cat. No.: HY-D0150
CAS No.: 107091-89-4
Cat. No.: HY-160412
CAS No.: 2248726-53-4
Synonyms: SAR-441566; TNFα activity modulator 3
Target:
Research Areas:
Balinatunfib (SAR-441566) is an orally active inhibitor of TNFR1 signaling. By binding to the central pocket of the soluble TNFα (sTNFα) trimer, Balinatunfib stabilizes an asymmetric conformation, blocking its binding to TNFR1 (without affecting TNFR2) and thus inhibiting downstream pathways. Balinatunfib has anti-inflammatory activity, and can be used in the study of autoimmune diseases .
Cat. No.: HY-P99430
CAS No.: 2296827-07-9
Synonyms: EM901; CC-93269
Target:
Research Areas:
Cat. No.: HY-W018845
CAS No.: 12354-84-6
Synonyms: Pentamethylcyclopentadienyliridium(III) chloride,dimer
Target:
Research Areas:
UCB-6876 is a TNFα inhibitor. UCB-6876 specifically binds to the asymmetric crystalline form of TNF-α trimer with a KD of 22 μM. UCB-6876 is applicable to research related to autoimmune diseases (rheumatoid arthritis and Crohn's disease) .
Cat. No.: HY-40228
CAS No.: 196929-78-9
Synonyms: (R)-2-Methylpropane-2-sulfinamide
Cat. No.: HY-W127776
CAS No.: 176736-49-5
Synonyms: Ethylenediaminetetraacetic acid zinc disodium tetrahydrate
Cat. No.: HY-69348
CAS No.: 102308-32-7
Research Areas:
Tetradecyltrimethylammonium bromide (TTAB; TTABr; MiTMAB), an organic building block, is a cationic surfactant with asymmetrical structure .
Cat. No.: HY-W002530
CAS No.: 126456-43-7
Cat. No.: HY-138053
CAS No.: 90831-71-3
Synonyms: Ristomycin III
Target:
Research Areas:
Ristocetin A sulfate (Ristomycin III) is a glycopeptide antibiotic that binds to von Willebrand factor (VWF) and bacterial cell wall components. Ristocetin A sulfate interferes with the biosynthesis of bacterial peptidoglycan by inhibiting transpeptidation. As an inducer of platelet adhesion and aggregation, Ristocetin A sulfate drives conformational changes by binding to the A1 domain of VWF, thereby activating downstream signaling pathways and promoting cytoskeletal rearrangement. Ristocetin A sulfate not only enhances platelet adhesion and spreading on immobilized VWF, but also induces the formation of asymmetric dimers with anticooperativity between platelets and plasma VWF. Ristocetin A sulfate is widely used in studies related to thromboembolic diseases and bacterial infections .
Synonyms: A22 hydrochloride
MreB Perturbing Compound A22 hydrochloride (A22 hydrochloride) is a reversible MreB inhibitor and antimicrobial agent that exhibits bacteriostatic activity against Escherichia coli, with low activity against Gram-positive bacteria. MreB Perturbing Compound A22 hydrochloride rapidly and reversally delocalizes MreB from the helical/circular structures in cells, impairs MreB function, and reduces the binding of MreB to the chromosomal region proximal to the replication origin. MreB Perturbing Compound A22 hydrochloride alters the cell morphology of caulobacters to round/lemon-shaped, slows caulobacter growth, blocks their cell division, and induces the formation of spherical morphology, asymmetric division, and anucleate cells in Escherichia coli. MreB Perturbing Compound A22 hydrochloride is used for studies related to bacterial rod-shaped morphology determination, chromosome segregation, and cell division mechanisms .
Cat. No.: HY-W019833
CAS No.: 76343-22-1
Synonyms: PC(14:0/18:0); 1-Myristoyl-2-stearoyl-sn-glycero-3-phosphocholine
Target:
Cat. No.: HY-W012874
CAS No.: 632-20-2
Synonyms: H-D-Thr-OH
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
