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  3. (R)-(+)-tert-Butylsulfinamide

(R)-(+)-tert-Butylsulfinamide  (Synonyms: (R)-2-Methylpropane-2-sulfinamide)

Cat. No.: HY-40228 Pureza: 99.95%
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(R)-(+)-tert-Butylsulfinamide ((R)-2-Methylpropane-2-sulfinamide) is a chiral reagent commonly used in the asymmetric synthesis of compounds such as amines, amino acids, and amino alcohols. (R)-(+)-tert-Butylsulfinamide achieves stereoselective reactions by condensing with carbonyl groups to form sulfinyl imine intermediates, and after the reaction, this group can be removed under acidic conditions to obtain the target product.

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(R)-(+)-tert-Butylsulfinamide

(R)-(+)-tert-Butylsulfinamide Estructura química

No. CAS : 196929-78-9

Tamaño Precio Stock Cantidad
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
En stock
Solution
10 mM * 1 mL in DMSO En stock
Solid
25 g En stock
50 g   Obtener un presupuesto  

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Descripciòn

(R)-(+)-tert-Butylsulfinamide ((R)-2-Methylpropane-2-sulfinamide) is a chiral reagent commonly used in the asymmetric synthesis of compounds such as amines, amino acids, and amino alcohols. (R)-(+)-tert-Butylsulfinamide achieves stereoselective reactions by condensing with carbonyl groups to form sulfinyl imine intermediates, and after the reaction, this group can be removed under acidic conditions to obtain the target product[1][2].

In Vitro

(R)-(+)-tert-Butylsulfinamide can efficiently participate in cycloaddition and cyclization reactions of enynes and diynes through properties such as asymmetric induction, N-alkylation, and deprotection or oxidation under mild conditions, thereby constructing polycyclic scaffold libraries related to alkaloid and terpenoid natural products[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Peso molecular

121.20

Fòrmula

C4H11NOS

No. CAS
Appearance

Solid

Color

White to off-white

SMILES

CC([S@](N)=O)(C)C

Envío

Room temperature in continental US; may vary elsewhere.

Almacenamiento
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvente y solubilidad
In Vitro: 

DMSO : 100 mg/mL (825.08 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 8.2508 mL 41.2541 mL 82.5083 mL
5 mM 1.6502 mL 8.2508 mL 16.5016 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Calculadora de molaridad

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Pureza y Documentación

Purity: 99.95%

Referencias

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 8.2508 mL 41.2541 mL 82.5083 mL 206.2706 mL
5 mM 1.6502 mL 8.2508 mL 16.5017 mL 41.2541 mL
10 mM 0.8251 mL 4.1254 mL 8.2508 mL 20.6271 mL
15 mM 0.5501 mL 2.7503 mL 5.5006 mL 13.7514 mL
20 mM 0.4125 mL 2.0627 mL 4.1254 mL 10.3135 mL
25 mM 0.3300 mL 1.6502 mL 3.3003 mL 8.2508 mL
30 mM 0.2750 mL 1.3751 mL 2.7503 mL 6.8757 mL
40 mM 0.2063 mL 1.0314 mL 2.0627 mL 5.1568 mL
50 mM 0.1650 mL 0.8251 mL 1.6502 mL 4.1254 mL
60 mM 0.1375 mL 0.6876 mL 1.3751 mL 3.4378 mL
80 mM 0.1031 mL 0.5157 mL 1.0314 mL 2.5784 mL
100 mM 0.0825 mL 0.4125 mL 0.8251 mL 2.0627 mL
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(R)-(+)-tert-Butylsulfinamide Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Nombre del producto:
(R)-(+)-tert-Butylsulfinamide
Cat. No.:
HY-40228
Cantidad:
MCE Japan Authorized Agent: