D-(-)-Quinic acid
Based on 3 publication(s) in Google Scholar
D-(-)-Quinic acid scavenges hydrogen peroxide (IC50=87.11 μg/mL) and exhibits antioxidant activity. D-(-)-Quinic acid is the inhibitor for MAO and α-Glucosidase (IC50 =93.75 μg/mL). D-(-)-Quinic acid is orally active.
For research use only. We do not sell to patients.
- Purity: 98.0%
- CAS No.: 77-95-2
- Formula: C7H12O6
- Molecular Weight:192.17
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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4,5-Dicaffeoylquinic acid
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Neochlorogenic acid
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HY-N0464R
D-(-)-Quinic acid (Standard)
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HY-Y1069
(S)-Malic acid
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HY-Y1069R
(S)-Malic acid (Standard)
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HY-N0159
Paeonol
Publications Citing Use of MedChemExpress (MCE) D-(-)-Quinic acid
MoreAll Endogenous Metabolite Isoforms
More
Biological Activity
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Microbial Metabolite |
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| MT2 | ED50 |
>1823 μM
Compound: quinic acid
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Concentration that inhibits Human Immunodeficiency Virus Type 1 (HIV-1)-induced death of MT-2 cells
Concentration that inhibits Human Immunodeficiency Virus Type 1 (HIV-1)-induced death of MT-2 cells
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[PMID: 9986720] |
D-(-)-Quinic acid (200-400 mg/kg, po, once daily for 10 days) reduces the levels of AChE, malondialdehyde and nitrite, increases the expression of GSH, catalase and SOD in brain tissue, improves the cognitive dysfunction of rats in aluminum ion-induced dementia rat models[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Obese mouse model induced by high-fat diet[1]
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Dosage:75-300 mg/kg
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Administration:po, once daily for 49 days
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Result:Reduced the body weight, liver weight, blood lipid levels, liver function indexes and inflammatory factor levels of obese mice. Improved liver tissue pathological changes.
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Animal Model:Aluminum ion-induced dementia rat models[2]
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Dosage:200-400 mg/kg
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Administration:po, once daily for 10 days
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Result:Improved the escape latency (ELT) and target quadrant residence in morris water maze test.
Increased locomotor activity in actophotometer test.
Reduced neuronal degeneration and preserved normal tissue structure in hippocampus and cortex.
Chemical Information
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CAS No. 77-95-2
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Appearance Solid
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Molecular Weight 192.17
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Formula C7H12O6
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Color White to off-white
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SMILES
O=C([C@]1(O)C[C@@H](O)[C@@H](O)[C@H](O)C1)O
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 2 years -20°C 1 year
Publications (3)
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Journal Impact Factor
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Most Recent
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Phytomedicine
Protective effects of E Se tea extracts against alcoholic fatty liver disease induced by high fat/alcohol diet: In vivo biological evaluation and molecular docking study. [Abstract]2022 Jul:101:154113. PMID: 35490493 -
Food Chem
Flavonoid-mediated metabolic underpinning quality variation in red bud-sport pear mutants. [Abstract]2025 Oct 15:489:144992. PMID: 40466530 -
Food Funct
Protective effects of a herbal combination (Dimocarpus longan and Orthosiphon stamineus) on metabolic-associated fatty liver disease via the ERα-PI3K-AKT pathway. [Abstract]2026 Feb 23. PMID: 41729581
Solvent & Solubility
H2O : 116.67 mg/mL (607.13 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
For the following dissolution methods, please prepare the working solution directly:
It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Add each solvent one by one: PBS
Solubility: 100 mg/mL (520.38 mM); Clear solution; Need ultrasonic
Purity & Documentation
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Data Sheet (278 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
[1]. Dong J, et al., Protective effect of D-(-)-quinic acid as food supplement in modulating AMP-activated protein kinase signalling pathway activation in HFD induced obesity. Hum Exp Toxicol. 2022 Jan-Dec;41:9603271221119804. [Content Brief]
[2]. Liu L, et al., Neuroprotective Effects of D-(-)-Quinic Acid on Aluminum Chloride-Induced Dementia in Rats. Evid Based Complement Alternat Med. 2020 May 11;2020:5602597. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 5.2038 mL | 26.0190 mL | 52.0381 mL | 130.0952 mL |
| 5 mM | 1.0408 mL | 5.2038 mL | 10.4076 mL | 26.0190 mL | |
| 10 mM | 0.5204 mL | 2.6019 mL | 5.2038 mL | 13.0095 mL | |
| 15 mM | 0.3469 mL | 1.7346 mL | 3.4692 mL | 8.6730 mL | |
| 20 mM | 0.2602 mL | 1.3010 mL | 2.6019 mL | 6.5048 mL | |
| 25 mM | 0.2082 mL | 1.0408 mL | 2.0815 mL | 5.2038 mL | |
| 30 mM | 0.1735 mL | 0.8673 mL | 1.7346 mL | 4.3365 mL | |
| 40 mM | 0.1301 mL | 0.6505 mL | 1.3010 mL | 3.2524 mL | |
| 50 mM | 0.1041 mL | 0.5204 mL | 1.0408 mL | 2.6019 mL | |
| 60 mM | 0.0867 mL | 0.4337 mL | 0.8673 mL | 2.1683 mL | |
| 80 mM | 0.0650 mL | 0.3252 mL | 0.6505 mL | 1.6262 mL | |
| 100 mM | 0.0520 mL | 0.2602 mL | 0.5204 mL | 1.3010 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
D-(-)-Quinic acid Related Classifications
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