2. JAK/STAT Signaling Protein Tyrosine Kinase/RTK
  3. EGFR
  4. EGFR T790M Recombinant Human Active Protein Kinase

EGFR T790M Recombinant Human Active Protein Kinase 

製品番号: HY-E70709
取扱説明書 Technical Support

EGFR is a driver of tumorigenesis. EGFR is mainly found in an auto-inhibited, dimerization-incompetent, state at the plasma membrane (PM). Ligand binding promotes receptor dimerization, which determines a series of structural rearrangements that are conveyed to the cytoplasmic domain allowing the formation of asymmetric dimers between the two juxtaposed catalytic domains. EGFR has multiple mutants. EGFR T790M Recombinant Human Active Protein Kinase is a recombinant EEGFR T790M protein that can be used to study EGFR T790M-related functions.

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EGFR T790M Recombinant Human Active Protein Kinase

EGFR T790M Recombinant Human Active Protein Kinase 構造式

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EGFR T790M Recombinant Human Active Protein Kinase 関連抗体

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製品説明

EGFR is a driver of tumorigenesis. EGFR is mainly found in an auto-inhibited, dimerization-incompetent, state at the plasma membrane (PM). Ligand binding promotes receptor dimerization, which determines a series of structural rearrangements that are conveyed to the cytoplasmic domain allowing the formation of asymmetric dimers between the two juxtaposed catalytic domains. EGFR has multiple mutants. EGFR T790M Recombinant Human Active Protein Kinase is a recombinant EEGFR T790M protein that can be used to study EGFR T790M-related functions[1].

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[EGFR T790M Recombinant Human Active Protein Kinase]
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.
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EGFR T790M Recombinant Human Active Protein Kinase Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

EGFR T790M Recombinant Human Active Protein KinaseEGFREpidermal growth factor receptorErbB-1HER1Inhibitorinhibitorinhibit

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製品名:
EGFR T790M Recombinant Human Active Protein Kinase
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