2. Anti-infection
  3. Bacterial Antibiotic
  4. MreB Perturbing Compound A22 hydrochloride

MreB Perturbing Compound A22 hydrochloride  (Synonyms: A22 hydrochloride)

Cat. No.: HY-118773 Purity: ≥99.0%
COA Handling Instructions

Molarity Calculator

MreB Perturbing Compound A22 hydrochloride is a benzylisothiourea compound that interacts with the ATP binding site of MreB rapidly and reversibly. MreB Perturbing Compound A22 hydrochloride blocks normal rod shape formation and inhibits chromosome partitioning in E. coli, inhibiting growth (MIC=3.1 µg/ml).

For research use only. We do not sell to patients.

MreB Perturbing Compound A22 hydrochloride Chemical Structure

MreB Perturbing Compound A22 hydrochloride Chemical Structure

CAS No. : 22816-60-0

Size Price Stock Quantity
1 mg USD 35 In-stock
5 mg USD 69 In-stock
10 mg USD 90 In-stock
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Based on 1 publication(s) in Google Scholar

MreB Perturbing Compound A22 hydrochloride Related Antibodies

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Description

MreB Perturbing Compound A22 hydrochloride is a benzylisothiourea compound that interacts with the ATP binding site of MreB rapidly and reversibly. MreB Perturbing Compound A22 hydrochloride blocks normal rod shape formation and inhibits chromosome partitioning in E. coli, inhibiting growth (MIC=3.1 µg/ml).

Molecular Weight

271.59

Formula

C8H9Cl3N2S
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

ClC1=CC(CSC(N)=N)=CC=C1Cl.Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : ≥ 20 mg/mL (73.64 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

DMF : ≥ 20 mg/mL (73.64 mM)

Ethanol : ≥ 1 mg/mL (3.68 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.6820 mL 18.4101 mL 36.8202 mL
5 mM 0.7364 mL 3.6820 mL 7.3640 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: ≥99.0%

COA (247 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
Ethanol / DMSO / DMF 1 mM 3.6820 mL 18.4101 mL 36.8202 mL 92.0505 mL
DMSO / DMF 5 mM 0.7364 mL 3.6820 mL 7.3640 mL 18.4101 mL
10 mM 0.3682 mL 1.8410 mL 3.6820 mL 9.2051 mL
15 mM 0.2455 mL 1.2273 mL 2.4547 mL 6.1367 mL
20 mM 0.1841 mL 0.9205 mL 1.8410 mL 4.6025 mL
25 mM 0.1473 mL 0.7364 mL 1.4728 mL 3.6820 mL
30 mM 0.1227 mL 0.6137 mL 1.2273 mL 3.0684 mL
40 mM 0.0921 mL 0.4603 mL 0.9205 mL 2.3013 mL
50 mM 0.0736 mL 0.3682 mL 0.7364 mL 1.8410 mL
60 mM 0.0614 mL 0.3068 mL 0.6137 mL 1.5342 mL
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MreB Perturbing Compound A22 hydrochloride Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

MreB Perturbing Compound A2222816-60-0A22MreB Perturbing Compound A 22MreB Perturbing Compound A-22A 22A-22BacterialAntibioticInhibitorinhibitorinhibit

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