2. Anti-infection Cell Cycle/DNA Damage
  3. HIV Nucleoside Antimetabolite/Analog
  4. Dioxolane T

Dioxolane T is a nucleoside analogue. Dioxolane T exhibits anti-HIV activity.

For research use only. We do not sell to patients.

Dioxolane T

Dioxolane T Chemical Structure

CAS No. : 136982-89-3

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Dioxolane T Related Antibodies

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Description

Dioxolane T is a nucleoside analogue. Dioxolane T exhibits anti-HIV activity[1].

Cellular Effect
Cell Line Type Value Description References
CCRF-CEM EC50
0.68 μM
Compound: DOT
Antiviral activity against HIV1 LAI infected in CEM cells
Antiviral activity against HIV1 LAI infected in CEM cells
[PMID: 19153047]
CCRF-CEM IC50
> 100 μM
Compound: DOT
Cytotoxicity against human CEM cells after 3 days by MTT assay
Cytotoxicity against human CEM cells after 3 days by MTT assay
[PMID: 19153047]
PBMC IC50
> 100 μM
Compound: DOT
Cytotoxicity against human PBM cells after 3 days by MTT assay
Cytotoxicity against human PBM cells after 3 days by MTT assay
[PMID: 19153047]
Vero IC50
> 100 μM
Compound: 11
Cytotoxicity in vero cells.
Cytotoxicity in vero cells.
[PMID: 1597854]
Vero IC50
> 100 μM
Compound: DOT
Cytotoxicity against african green monkey Vero cells after 3 days by MTT assay
Cytotoxicity against african green monkey Vero cells after 3 days by MTT assay
[PMID: 19153047]
Molecular Weight

228.20

Formula

C9H12N2O5
CAS No.
SMILES

O=C1N(C=C(C(N1)=O)C)[C@@H]2O[C@@H](OC2)CO
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Dioxolane T Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Dioxolane T136982-89-3HIVNucleoside Antimetabolite/AnalogHuman immunodeficiency virus1,3 - Dioxolane - Pyrimidine NucleosidesAnti - HIV ActivityAsymmetric SynthesisStructure - Activity Relationship (SAR)Human Peripheral Blood Mononuclear Cells (PBMCs)AZT - Resistant VirusCytotoxicityNucleoside AnaloguesRetroviral InhibitionInhibitorinhibitorinhibit

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