Dioxolane T
Dioxolane T is a nucleoside analogue. Dioxolane T exhibits anti-HIV activity.
For research use only. We do not sell to patients.
- CAS No.: 136982-89-3
- Formula: C9H12N2O5
- Molecular Weight:228.20
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- Purity & Documentation
- References
-
Help & FAQs
Biological Activity
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| CCRF-CEM | EC50 |
0.68 μM
Compound: DOT
|
Antiviral activity against HIV1 LAI infected in CEM cells
Antiviral activity against HIV1 LAI infected in CEM cells
|
[PMID: 19153047] |
| CCRF-CEM | IC50 |
>100 μM
Compound: DOT
|
Cytotoxicity against human CEM cells after 3 days by MTT assay
Cytotoxicity against human CEM cells after 3 days by MTT assay
|
[PMID: 19153047] |
| PBMC | IC50 |
>100 μM
Compound: DOT
|
Cytotoxicity against human PBM cells after 3 days by MTT assay
Cytotoxicity against human PBM cells after 3 days by MTT assay
|
[PMID: 19153047] |
| Vero | IC50 |
>100 μM
Compound: 11
|
Cytotoxicity in vero cells.
Cytotoxicity in vero cells.
|
[PMID: 1597854] |
| Vero | IC50 |
>100 μM
Compound: DOT
|
Cytotoxicity against african green monkey Vero cells after 3 days by MTT assay
Cytotoxicity against african green monkey Vero cells after 3 days by MTT assay
|
[PMID: 19153047] |
Chemical Information
-
CAS No. 136982-89-3
-
Molecular Weight 228.20
-
Formula C9H12N2O5
-
SMILES
O=C1N(C=C(C(N1)=O)C)[C@@H]2O[C@@H](OC2)CO
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Dioxolane T Related Classifications
HY-107082 Related Classifications
Powered by Bioz
- Dioxolane T
- 136982-89-3
- HIV
- Nucleoside Antimetabolite/Analog
- 1,3 - Dioxolane - Pyrimidine Nucleosides
- Anti - HIV Activity
- Asymmetric Synthesis
- Structure - Activity Relationship (SAR)
- Human Peripheral Blood Mononuclear Cells (PBMCs)
- AZT - Resistant Virus
- Cytotoxicity
- Nucleoside Analogues
- Retroviral Inhibition
- Inhibitor
- inhibitor
- inhibit