Trimethidinium methosulfate

Cat. No.: HY-180382: Data Sheet Handling Instructions
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Trimethidinium methosulfate is an orally active ganglionic blocker with central antihypertensive activity. Trimethidinium methosulfate inhibits the conduction of sympathetic ganglia and reduces vascular contraction. Trimethidinium methosulfate acts on the cerebrovascular motor center and lowers peripheral vascular resistance. Trimethidinium methosulfate has cholinergic nerve inhibitory side effects, but they are relatively mild. Trimethidinium methosulfate can be used in hypertension research.

For research use only. We do not sell to patients.

Trimethidinium methosulfate Chemical Structure

CAS No. : 14149-43-0

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Description	Trimethidinium methosulfate is an orally active ganglionic blocker with central antihypertensive activity. Trimethidinium methosulfate inhibits the conduction of sympathetic ganglia and reduces vascular contraction. Trimethidinium methosulfate acts on the cerebrovascular motor center and lowers peripheral vascular resistance. Trimethidinium methosulfate has cholinergic nerve inhibitory side effects, but they are relatively mild. Trimethidinium methosulfate can be used in hypertension research^[1]^[2].
Molecular Weight	490.68
Formula	C₁₉H₄₂N₂O₈S₂
CAS No.	14149-43-0
SMILES	O=S([O-])(OC)=O.CC1(C2CCC1(C[N+](CCC[N+](C)(C)C)(C2)C)C)C.O=S([O-])(OC)=O
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Data Sheet (274 KB) Handling Instructions (2659 KB)
References	[1]. PELNER L, WALDMAN S. Trimethidinium methosulfate in the treatment of moderate and severe hypertension. J Am Geriatr Soc. 1960 Mar;8:168-76. [Content Brief] [2]. BORHANI NO. Use of trimethidinium methosulfate (a new ganglionic blocking agent) in the treatment of hypertension. Ann Intern Med. 1959 Nov;51:983-92. [Content Brief]