Asymmetric dimethylarginine dihydrochloride (Synonyms: NG,NG-Dimethylarginine dihydrochloride)

Cat. No.: HY-113216B: Data Sheet
COA

SDS
Handling Instructions
FAQs
Technical Support

Asymmetric dimethylarginine dihydrochloride is an endogenous NO synthase inhibitor that reduces NO production, which contributes to endothelial dysfunction and cardiovascular disease.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

Asymmetric dimethylarginine dihydrochloride 화학구조

CAS No. : 220805-22-1

사이즈	가격	재고
5 mg		Ask For Quote & Lead Time

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

This product is a controlled substance and not for sale in your territory.

Other In-stock Forms of Asymmetric dimethylarginine dihydrochloride:

Asymmetric dimethylarginine

Other Forms of Asymmetric dimethylarginine dihydrochloride:

Asymmetric-dimethylarginine-d₆ dihydrochloride In-stock
Asymmetric dimethylarginine In-stock

5 Publications Citing Use of MCE Asymmetric dimethylarginine dihydrochloride

Featured Recommendations

•Related Screening Libraries:

•Related Small Molecules:

•Related Proteins:

View All NO Synthase Isoform Specific Products:

View All Isoforms

nNOS iNOS eNOS

Biological Activity
순도&문서
References
고객리뷰

제품 설명

Asymmetric dimethylarginine dihydrochloride is an endogenous NO synthase inhibitor that reduces NO production, which contributes to endothelial dysfunction and cardiovascular disease^[1].

분자량

275.18

화학식

C₈H₂₀Cl₂N₄O₂

CAS No.

220805-22-1

Appearance

Solid

Color

White to off-white

SMILES

[H]Cl.[H]Cl.CN(C)C(NCCC[C@H](N)C(O)=O)=N

선적

Room temperature in continental US; may vary elsewhere.

보관

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

용액&용해도

In Vitro:

H₂O : 100 mg/mL (363.40 mM; Need ultrasonic and warming)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	3.6340 mL	18.1699 mL	36.3399 mL
5 mM	0.7268 mL	3.6340 mL	7.2680 mL
10 mM	0.3634 mL	1.8170 mL	3.6340 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

몰농도 계산기
농도 희석 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

순도&문서

Purity: 99.99%

Select Batch:

Data Sheet (270 KB) SDS (393 KB)

COA (245 KB)

Handling Instructions (2659 KB)

References

[1]. Latika Sibal, et al. The Role of Asymmetric Dimethylarginine (ADMA) in Endothelial Dysfunction and Cardiovascular Disease. Curr Cardiol Rev. 2010 May;6(2):82-90.

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O	1 mM	3.6340 mL	18.1699 mL	36.3399 mL	90.8496 mL
	5 mM	0.7268 mL	3.6340 mL	7.2680 mL	18.1699 mL
	10 mM	0.3634 mL	1.8170 mL	3.6340 mL	9.0850 mL
	15 mM	0.2423 mL	1.2113 mL	2.4227 mL	6.0566 mL
	20 mM	0.1817 mL	0.9085 mL	1.8170 mL	4.5425 mL
	25 mM	0.1454 mL	0.7268 mL	1.4536 mL	3.6340 mL
	30 mM	0.1211 mL	0.6057 mL	1.2113 mL	3.0283 mL
	40 mM	0.0908 mL	0.4542 mL	0.9085 mL	2.2712 mL
	50 mM	0.0727 mL	0.3634 mL	0.7268 mL	1.8170 mL
	60 mM	0.0606 mL	0.3028 mL	0.6057 mL	1.5142 mL
	80 mM	0.0454 mL	0.2271 mL	0.4542 mL	1.1356 mL
	100 mM	0.0363 mL	0.1817 mL	0.3634 mL	0.9085 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Asymmetric dimethylarginine dihydrochloride Related Classifications

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Asymmetric dimethylarginine220805-22-1NG,NG-DimethylarginineNO SynthaseNitric oxide synthasesNOSInhibitorinhibitorinhibit

최근 본 상품:

상품명

Requested Quantity *

고객명 *

호칭

메일주소 *

전화번호 *

Department

회사명 *

City

도

Country or Region *

비고

상품명

Lot #

고객명 *

메일주소 *

전화번호

Department *