Asymmetric dimethylarginine dihydrochloride
Based on 5 publication(s) in Google Scholar
Asymmetric dimethylarginine dihydrochloride is an endogenous NO synthase inhibitor that reduces NO production, which contributes to endothelial dysfunction and cardiovascular disease.
For research use only. We do not sell to patients.
- CAS No.: 220805-22-1
- Formula: C8H20Cl2N4O2
- Molecular Weight:275.18
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Storage:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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HY-100986
L-NIO dihydrochloride -
HY-101410
SDMA -
HY-131898
PTIO -
HY-113216BS
Asymmetric-dimethylarginine-d6 dihydrochloride -
HY-18729A
L-NAME hydrochloride -
HY-126193
JS-K -
HY-100954
2,4-Diamino-6-hydroxypyrimidine -
HY-12116
L-NIL -
HY-12119
GW274150 -
HY-79457
S-Methylisothiourea sulfate -
HY-101410R
SDMA (Standard) -
HY-12115
NG-nitro-L-arginine
Publications Citing Use of MedChemExpress (MCE) Asymmetric dimethylarginine dihydrochloride
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Biological Activity
Description
Chemical Information
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CAS No. 220805-22-1
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Appearance Solid
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Molecular Weight 275.18
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Formula C8H20Cl2N4O2
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Color White to off-white
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SMILES
[H]Cl.[H]Cl.CN(C)C(NCCC[C@H](N)C(O)=O)=N
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Synonyms
NG,NG-Dimethylarginine dihydrochloride
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Publications (5)
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Journal Impact Factor
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Most Recent
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Cell Metab
Machine-learning-guided discovery of SLC25A45 as a mediator of mitochondrial methylated amino acid import and carnitine synthesis. [Abstract]2025 Oct 10:S1550-4131(25)00434-6. PMID: 41075780 -
Cell Metab
Lighting up arginine metabolism reveals its functional diversity in physiology and pathology. [Abstract]2025 Jan 7;37(1):291-304.e9. PMID: 39413790 -
Cell Death Dis
DDAH-1 maintains endoplasmic reticulum-mitochondria contacts and protects dopaminergic neurons in Parkinson's disease. [Abstract]2024 Jun 7;15(6):399. PMID: 38849335 -
EMBO Rep
Tudor-based proteomic strategy pan-specifically enriches and identifies protein arginine methylation. [Abstract]2025 Oct 20. PMID: 41116072 -
Int J Mol Sci
2024 Jul 19;25(14):7897. PMID: 39063139
Solvent & Solubility
In Vitro:
H2O : 100 mg/mL (363.40 mM; Need ultrasonic and warming)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (270 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 3.6340 mL | 18.1699 mL | 36.3399 mL | 90.8496 mL |
| 5 mM | 0.7268 mL | 3.6340 mL | 7.2680 mL | 18.1699 mL | |
| 10 mM | 0.3634 mL | 1.8170 mL | 3.6340 mL | 9.0850 mL | |
| 15 mM | 0.2423 mL | 1.2113 mL | 2.4227 mL | 6.0566 mL | |
| 20 mM | 0.1817 mL | 0.9085 mL | 1.8170 mL | 4.5425 mL | |
| 25 mM | 0.1454 mL | 0.7268 mL | 1.4536 mL | 3.6340 mL | |
| 30 mM | 0.1211 mL | 0.6057 mL | 1.2113 mL | 3.0283 mL | |
| 40 mM | 0.0908 mL | 0.4542 mL | 0.9085 mL | 2.2712 mL | |
| 50 mM | 0.0727 mL | 0.3634 mL | 0.7268 mL | 1.8170 mL | |
| 60 mM | 0.0606 mL | 0.3028 mL | 0.6057 mL | 1.5142 mL | |
| 80 mM | 0.0454 mL | 0.2271 mL | 0.4542 mL | 1.1356 mL | |
| 100 mM | 0.0363 mL | 0.1817 mL | 0.3634 mL | 0.9085 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Asymmetric dimethylarginine dihydrochloride Related Classifications
HY-113216B Related Classifications
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