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benzotriazole-N,N,N',N'-tetramethylurea hexafluorophosphate

" in MedChemExpress (MCE) Product Catalog:

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3

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11

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-102007A
    Gamitrinib TPP hexafluorophosphate
    Maximum Cited Publications
    13 Publications Verification

    HSP Cancer
    Gamitrinib TPP hexafluorophosphate is a Gamitrinib (GA) mitochondrial matrix inhibitor. Gamitrinib TPP hexafluorophosphate is a mitochondrial targeted HSP90 inhibitor with anti-cancer activity.
    Gamitrinib TPP hexafluorophosphate
  • HY-134124

    Reactive Oxygen Species (ROS) Metabolic Disease
    Glutathione ethyl ester is a cell-permeable GSH donor and provides an efficient supply of GSH to the oocyte. Glutathione ethyl ester shows positive effect on the in vitro production of embryos by enhancement of the antioxidative defense .
    Glutathione ethyl ester
  • HY-D1583
    Cyanine5 DBCO hexafluorophosphate
    3 Publications Verification

    DBCO-Cy5 hexafluorophosphate; Cyanine5 dibenzocyclooctyne hexafluorophosphate

    Fluorescent Dye Others
    Cyanine5 DBCO (DBCO-Cy5) hexafluorophosphate is a low-toxicity azide reactive probe (NIR fluorescent dye), for imaging azide-labeled biomolecules via a copper-free "click-through" reaction. Cyanine5 DBCO hexafluorophosphate has no apparent cytotoxicity or animal toxicity and shows no damage to the physiological functions of cells other than the target cells (azide-labeled cells). Cyanine5 DBCO hexafluorophosphate can be used to label and track cells in vitro and in vivo (Ex=635 nm, Em=650-700 nm) .
    Cyanine5 DBCO hexafluorophosphate
  • HY-P10272

    PTG-300

    Ferroportin Others
    Rusfertide is a peptide mimetic of natural hepcidin, which targets and degrades ferroportin, reduces serum iron and transferrin-saturation, and thus regulates the production of red blood cells. Rusfertide ameliorates the polycythemia vera, β-thalassemia and hereditary hemochromatosis .
    Rusfertide
  • HY-A0248A
    Polymyxin B1
    1 Publications Verification

    Bacterial Infection
    Polymyxin B1 is a potent antimicrobial lipopeptide first derived from Bacilus polymyxa. Polymyxin B1 is the major component in Polymyxin B (HY-A0248). Polymyxin B1 can induce lysis of bacterial cells through interaction with their membranes. Polymyxin B1 has the potential for multidrug-resistant Gram-negative bacterial infections treatment .
    Polymyxin B1
  • HY-W011556

    TCFH

    Drug Isomer Cancer
    N,N,N',N'-Tetramethylchloroformamidinium hexafluorophosphate (TCFH) is a powerful coupling and derivatizing reagent for ester prodrug synthesis. N,N,N',N'-Tetramethylchloroformamidinium hexafluorophosphate can be used for antitumor drugs before medicine research .
    N,N,N',N'-Tetramethylchloroformamidinium hexafluorophosphate
  • HY-W010951

    O-(6-Chlorobenzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate

    Biochemical Assay Reagents Others
    HCTU is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
    HCTU
  • HY-D0177

    benzotriazole-1-yl-oxytripyrrolidinophosphonium hexafluorophosphate

    Biochemical Assay Reagents Others
    (Benzotriazol-1-yloxy)tripyrrolidinophosphonium hexafluorophosphate (Benzotriazole-1-yl-oxytripyrrolidinophosphonium hexafluorophosphate) is a peptide coupling reagent and BOP analog. (Benzotriazol-1-yloxy)tripyrrolidinophosphonium hexafluorophosphate promotes the reaction of amino and carboxyl groups to form peptide bonds. (Benzotriazol-1-yloxy)tripyrrolidinophosphonium hexafluorophosphate can be used in the synthesis of peptide compounds .
    (Benzotriazol-1-yloxy)tripyrrolidinophosphonium hexafluorophosphate
  • HY-Y0973

    Biochemical Assay Reagents Drug Intermediate Others
    BOP hexafluorophosphate is a phosphonium-type condensing agent. BOP hexafluorophosphate activates the carboxylic acid component to form a highly reactive O-benzotriazole ester (active ester) intermediate, which then reacts with the amino component to form an amide bond (peptide bond). BOP hexafluorophosphate is applicable to solid-phase polypeptide synthesis and nucleoside modification .
    BOP hexafluorophosphate
  • HY-P1108A
    Astressin 2B TFA
    1 Publications Verification

    CRFR Neurological Disease Inflammation/Immunology
    Astressin 2B TFA is a blood-brain barrier-impermeable, highly selective CRFR2 antagonist (rCRFR2, IC50=0.57 nM). Astressin 2B TFA blocks the protective effects mediated by CRFR2, thereby exacerbating indomethacin (HY-14397)-induced hemorrhagic intestinal injury in rats. Astressin 2B TFA reverses the protective effects of Urocortin 1 against intestinal hypermotility, bacterial invasion and upregulation of inflammatory mediators. Astressin 2B TFA also blocks the anxiogenic effect of Urocortin 2 and attenuates stress-induced anxiety-related behaviors. In the Clostridioides difficile toxin A (C. difficile toxin A)-mediated enteritis model, Astressin 2B TFA mimics the phenotype of CRFR2-deficient mice, significantly exacerbating intestinal epithelial damage, edema, neutrophil migration and the expression of multiple proinflammatory cytokines. Astressin 2B TFA is an important tool molecule for investigating the intestinal protective mechanisms of CRFR2 .
    Astressin 2B TFA
  • HY-P1108
    Astressin 2B
    1 Publications Verification

    CRFR Neurological Disease Inflammation/Immunology
    Astressin 2B is a blood-brain barrier-impermeable, highly selective CRFR2 antagonist (rCRFR2, IC50=0.57 nM). Astressin 2B blocks the protective effects mediated by CRFR2, thereby exacerbating indomethacin (HY-14397)-induced hemorrhagic intestinal injury in rats. Astressin 2B reverses the protective effects of Urocortin 1 against intestinal hypermotility, bacterial invasion and upregulation of inflammatory mediators. Astressin 2B also blocks the anxiogenic effect of Urocortin 2 and attenuates stress-induced anxiety-related behaviors. In the Clostridioides difficile toxin A (C. difficile toxin A)-mediated enteritis model, Astressin 2B mimics the phenotype of CRFR2-deficient mice, significantly exacerbating intestinal epithelial damage, edema, neutrophil migration and the expression of multiple proinflammatory cytokines. Astressin 2B is an important tool molecule for investigating the intestinal protective mechanisms of CRFR2 .
    Astressin 2B
  • HY-Y1699

    Biochemical Assay Reagents Others
    Tetrabutylammonium hexafluorophosphate is an organic-inorganic compound commonly used as an ionic solvent and catalyst. It can be used to catalyze or promote reactions in certain chemical reactions, and is widely used in batteries, solar cells and pigments. In addition, this compound is also widely used in organic synthesis and chemical analysis.
    Tetrabutylammonium hexafluorophosphate
  • HY-I0983S

    Isotope-Labeled Compounds Others
    1,1,3,3-Tetramethylurea-d12 is the deuterium labeled 1,1,3,3-Tetramethylurea .
    1,1,3,3-Tetramethylurea-d12
  • HY-P5290

    Radionuclide-Drug Conjugates (RDCs) PSMA Cancer
    HYNIC-PSMA is a ligand for molecular imaging of tumors. Hynic-psma consists of two components: HYNIC (6-hydrazinonicotinamide) and PSMA (Prostate-Specific Membrane Antigen). HYNIC is a compound used to attach radioactive isotopes to targeted molecules, such as 188Re-HYNIC-PSMA. PSMA is a membrane antigen that is specifically expressed on the surface of prostate cancer cells. HYNIC-PSMA can be used in prostate cancer research . HYNIC-PSMA can be used for the synthesis/research of Radionuclide-Drug Conjugates (RDCs).
    HYNIC-PSMA
  • HY-P10143

    Ac-Pro-Leu-Gly-[(S)-2-mercapto-4-methyl-pentanoyl]-Leu-Gly-OEt

    MMP Others
    MMP-2/MMP-9 Substrate (Ac-Pro-Leu-Gly-[(S)-2-mercapto-4-methyl-pentanoyl]-Leu-Gly-OEt) is a synthetic chromogenic polypeptide substrate whose core structure mimics the cleavage sites of MMP-2 and MMP-9 (gelatinase A and B) in collagen. After being hydrolyzed by collagenase, MMP-2/MMP-9 Substrate reacts with 4,4'-dithiodipyridine or Ellman's Reagent via its thiol fragment to produce a product with ultraviolet absorption properties .
    MMP-2/MMP-9 Substrate
  • HY-A0248AS

    Isotope-Labeled Compounds Bacterial Infection
    Polymyxin B1-d7 TFA is the deuterium labeled Polymyxin B1 TFA (HY-A0248A). Polymyxin B1 is a potent antimicrobial lipopeptide first derived from Bacilus polymyxa. Polymyxin B1 is the major component in Polymyxin B (HY-A0248). Polymyxin B1 can induce lysis of bacterial cells through interaction with their membranes. Polymyxin B1 has the potential for multidrug-resistant Gram-negative bacterial infections treatment .
    Polymyxin B1-d7 TFA
  • HY-D1622

    Cy3-DBCO hexafluorophosphate

    Fluorescent Dye Others
    Cyanine3 DBCO (Cy3-DBCO) hexafluorophosphate is a azide reactive probe, for imaging azide-labeled biomolecules via a copper-free "click-through" reaction.
    Cyanine3 DBCO hexafluorophosphate
  • HY-P2496

    Endothelin Receptor Fluorescent Dye NF-κB COX Prostaglandin Receptor Apoptosis TNF Receptor Interleukin Related MMP Cardiovascular Disease Inflammation/Immunology Cancer
    Endothelin 1 (swine, human), Alexa Fluor 488-labeled is an Endothelin-1 conjugated with Alexa Fluor 488 (HY-D1304). Endothelin-1 is an endogenous vasoconstrictor and agonist of ETA/ETB receptor. Endothelin 1 (swine, human) exerts effects including promoting mitosis, angiogenesis, tumor invasion and metastasis, and inhibiting apoptosis. Endothelin 1 (swine, human) induces inflammation and oxidative stress by activating the NF-κB pathway. Endothelin 1 (swine, human), Alexa Fluor 488-labeled is specifically designed for fluorescence imaging, flow cytometry or receptor localization studies, and can be used in research related to sepsis, atherosclerosis, systemic inflammatory response syndrome, cancer and congestive heart failure .
    Endothelin 1 (swine, human), Alexa Fluor 488-labeled
  • HY-P5292A

    Radionuclide-Drug Conjugates (RDCs) PSMA Cancer
    HYNIC-iPSMA TFA is a ligand for molecular imaging of tumors. Hynic-ipsma consists of two components: HYNIC (6-hydrazinonicotinamide) and iPSMA (Inhibitor of Prostate-Specific Membrane Antigen). HYNIC is a compound used to attach radioactive isotopes to targeted molecules. iPSMA is a specific inhibitor used to inhibit prostate-specific membrane antigen (PSMA). 68GA-labeled iPSMA has been used to detect prostate cancer by PET imaging. The further 99mTc-EDDA/HYNIC-iPSMA TFA has excellent specificity and sensitivity . HYNIC-iPSMA TFA can be used for the synthesis/research of Radionuclide-Drug Conjugates (RDCs).
    HYNIC-iPSMA TFA
  • HY-P5372A

    Protease Activated Receptor (PAR) Cancer
    Ala-parafluoroPhe-Arg-Cha-Cit-Tyr-NH2 TFA, a bioactive peptide, is a selective Protease activating receptor 1 (PAR-1) agonist over PAR-2. PAR-1 belongs to a subfamily of G-protein coupled receptors and is known to mediate the cellular effects of thrombin. In addition to its varied cellular effects of thrombin, PAR-1 has also been shown to coordinate with PAR-4 and regulate thrombin-induced hepatocellular carcinoma harboring thrombin formation within the tumor environment classified as 'coagulation type' .
    Ala-parafluoroPhe-Arg-Cha-Cit-Tyr-NH2 TFA
  • HY-136143

    Fluorescent Dye Others
    (BHQ-3)-OSu hexafluorophosphate is used for fluorescent labeling of protease substrates .
    (BHQ-3)-OSu hexafluorophosphate
  • HY-P10563

    BHV-1100

    CD38 Cancer
    Noraramtide (BHV-1100) is an antibody recruitment molecule. Noraramtide can specifically bind to CD38 molecules to recruit natural killer (NK) cells. Noraramtide enhances the ability of NK cells to kill tumor cells through antibody-dependent cellular cytotoxicity (ADCC). This mechanism allows NK cells to more effectively recognize and eliminate tumor cells while avoiding mutual killing between NK cells. Noraramtide can be used for the study of autologous cancer immunity .
    Noraramtide
  • HY-160937

    Ligands for Target Protein for PROTAC PARP Cancer
    AZD-9574-acid (Compound 70D) is a PARP-1 ligand. AZD-9574-acid serves as a Ligand for Target Protein for PROTAC for the synthesis of PARP-1 PROTAC degraders. AZD-9574-acid is applicable to cancer research .
    AZD-9574-acid
  • HY-P5292

    Radionuclide-Drug Conjugates (RDCs) PSMA Cancer
    HYNIC-iPSMA is a ligand for molecular imaging of tumors. Hynic-ipsma consists of two components: HYNIC (6-hydrazinonicotinamide) and iPSMA (Inhibitor of Prostate-Specific Membrane Antigen). HYNIC is a compound used to attach radioactive isotopes to targeted molecules. iPSMA is a specific inhibitor used to inhibit prostate-specific membrane antigen (PSMA). 68GA-labeled iPSMA has been used to detect prostate cancer by PET imaging. The further 99mTc-EDDA/HYNIC-iPSMA has excellent specificity and sensitivity . HYNIC-iPSMA can be used for the synthesis/research of Radionuclide-Drug Conjugates (RDCs).
    HYNIC-iPSMA
  • HY-P3066

    d(CH2)5Tyr(Et)VAVP

    Vasopressin Receptor Metabolic Disease
    SKF 100398 (d(CH2)5Tyr(Et)VAVP), an arginine vasopressin (AVP) analogue, is a specific antagonist of the antidiuretic effect of exogenous and endogenous AVP .
    SKF 100398
  • HY-128890A

    Biochemical Assay Reagents Others
    DOTA-NHS-ester (hexafluorophosphate TFA)is a bifunctional chelator (Bifunctional Chelator; BFC) and a macrocyclic DOTA derivative used for tumor pre-targeting. DOTA-NHS-ester (hexafluorophosphate TFA) can be used for conjugation of peptides and radionuclides.
    DOTA-NHS-ester hexafluorophosphate TFA
  • HY-W011734

    Biochemical Assay Reagents Others
    Tetramethylfluoroformamidinium (hexafluorophosphate) is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
    Tetramethylfluoroformamidinium hexafluorophosphate
  • HY-W127673

    Biochemical Assay Reagents Others
    Tetramethylammonium Hexafluorophosphate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
    Tetramethylammonium hexafluorophosphate
  • HY-W034796

    Biochemical Assay Reagents Others
    Cobaltocene hexafluorophosphate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
    Cobaltocene hexafluorophosphate
  • HY-DY1068

    Fluorescent Dye Others
    Cyanine5 DBCO (DBCO-Cy5) hexafluorophosphate (solution) is a low-toxicity azide reactive probe (NIR fluorescent dye) , for imaging azide-labeled biomolecules via a copper-free "click-through" reaction. Cyanine5 DBCO hexafluorophosphate has no apparent cytotoxicity or animal toxicity and shows no damage to the physiological functions of cells other than the target cells (azide-labeled cells). Cyanine5 DBCO hexafluorophosphate can be used to label and track cells in vitro and in vivo (Ex=635 nm, Em=650-700 nm) .
    Solvent and concentration: DMSO: 10 mM
    Cyanine5 DBCO hexafluorophosphate (solution)
  • HY-W035145

    Drug Intermediate Others
    Tris(2,2′-bipyridine)ruthenium(II)hexafluorophosphate can be used to prepare Ru(II)-containing photodynamic therapy (PDT) photosensitizers .
    Tris2,2′-bipyridineruthenium(II) hexafluorophosphate
  • HY-W035155

    Drug Intermediate Endogenous Metabolite
    (1,5-Cyclooctadiene)bis(methyldiphenylphosphine)iridium(I) hexafluorophosphate is a highly efficient catalyst with excellent hydrogenation activity. It can catalyze the reaction of hydrogen and organic substrates in various chemical reactions. This compound is often used to synthesize important chemical intermediates and compounds.
    (1,5-Cyclooctadiene)bis(methyldiphenylphosphine)iridium(I) hexafluorophosphate
  • HY-P10828

    Virus Protease Infection Inflammation/Immunology
    MAPI is a polypeptide irreversible 3C cysteine protease (SV3CP) inhibitor. MAPI inhibits SV3CP by covalently binding its C-terminal Michael-acceptor extension to the active site thiol of SV3CP Cys 139. MAPI is promising for research of noroviruses infection .
    MAPI
  • HY-P5372

    Protease Activated Receptor (PAR) Cancer
    Ala-parafluoroPhe-Arg-Cha-Cit-Tyr-NH2, a bioactive peptide, is a selective Protease activating receptor 1 (PAR-1) agonist over PAR-2. PAR-1 belongs to a subfamily of G-protein coupled receptors and is known to mediate the cellular effects of thrombin. In addition to its varied cellular effects of thrombin, PAR-1 has also been shown to coordinate with PAR-4 and regulate thrombin-induced hepatocellular carcinoma harboring thrombin formation within the tumor environment classified as 'coagulation type' .
    Ala-parafluoroPhe-Arg-Cha-Cit-Tyr-NH2
  • HY-P10472

    GnRH Receptor Endocrinology
    Azaline B is an antagonist for gonadotropin-releasing hormone (GnRH) with IC50 of 1.37 nM, Azaline B can be used in research of sex hormone-related pathological states, ovulation induction and male contraception .
    Azaline B
  • HY-131885

    GABA Receptor Neurological Disease
    RuBi-Glutamate hexafluorophosphate sodium is a neuronal activator. RuBi-Glutamate hexafluorophosphate sodium photocleaves to release glutamate upon one- or two-photon excitation, activating glutamate receptors in cortical pyramidal neurons. RuBi-Glutamate hexafluorophosphate sodium reduces peak amplitude of evoked GABAergic inhibitory postsynaptic currents in its caged form. RuBi-Glutamate hexafluorophosphate sodium can be used for the research of Huntington's disease .
    RuBi-Glutamate hexafluorophosphate sodium
  • HY-161102

    Autophagy Cancer
    [Ru(phen)2(xant)] hexafluorophosphate is an inducer of Autophagy. [Ru(phen)2(xant)] hexafluorophosphate eliminates CRC stem cells by targeting the chaperone Hsp90. [Ru(phen)2(xant)] hexafluorophosphate reduces cell migration and invasion .
    [Ru(phen)2(xant)] hexafluorophosphate
  • HY-W790758

    Biochemical Assay Reagents
    Tripropylammonium hexafluorophosphate is a potent, cell-permeable free radical scavenger suitable for the detection of superoxide radicals and peroxynitrite in vitro.
    Tripropylammonium hexafluorophosphate
  • HY-W099577

    Biochemical Assay Reagents Others
    N-hexadecyltrimethylammoniumhexafluorophosphate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
    N-Hexadecyltrimethylammonium hexafluorophosphate
  • HY-P2592

    Cholecystokinin Receptor Others
    Ro 23-7014 is an appetite suppressant. Ro 23-7014 is an analog of cholecystokinin (CCK-7) .
    Ro 23-7014
  • HY-102007AR

    Reference Standards HSP Cancer
    Gamitrinib TPP hexafluorophosphate (Standard) is the analytical standard of Gamitrinib TPP hexafluorophosphate (HY-102007A). This product is intended for research and analytical applications. Gamitrinib TPP hexafluorophosphate is a Gamitrinib (GA) mitochondrial matrix inhibitor. Gamitrinib TPP hexafluorophosphate is a mitochondrial targeted HSP90 inhibitor with anti-cancer activity.
    Gamitrinib TPP hexafluorophosphate (Standard)
  • HY-125628

    Endogenous Metabolite Infection
    Kahalalide A is an anti-mycobacterial compound with antimicrobial activity. Kahalalide A is derived from the marine mollusk Elysia rufescens. Kahalalide A has attracted extensive attention in natural product research due to its potential medicinal value .
    Kahalalide A
  • HY-W091791

    Biochemical Assay Reagents Others
    2-Azido-1,3-dimethylimidazolinium hexafluorophosphate (compound 166) is a biochemical assay reagent that can be prepared from primary amines, metal-free diazo transfer .
    2-Azido-1,3-dimethylimidazolinium hexafluorophosphate
  • HY-W539814

    MOFs Others
    1,1'-[1,4-Phenylenebis(methylene)]bis(4,4'-bipyridinium) Bis (hexafluorophosphate) is a metal-organic framework (MOF).
    1,1'-[1,4-Phenylenebis(methylene)]bis(4,4'-bipyridinium) Bis hexafluorophosphate
  • HY-W456399

    MOFs Others
    (E)-3-Ethyl-2-(4-(1,2,2-triphenylvinyl)styryl)benzo[d]thiazol-3-ium hexafluorophosphate(V) is a metal-organic framework (MOF).
    (E)-3-Ethyl-2-(4-(1,2,2-triphenylvinyl)styryl)benzo[d]thiazol-3-ium hexafluorophosphate(V)
  • HY-W333530

    1,1'-[Biphenyl-4,4'-diylbis(methylene)]bis(4,4'-bipyridinium) bishexafluorophosphate

    MOFs Others
    1,1''-([1,1'-Biphenyl]-4,4'-diylbis(methylene))bis(([4,4'-bipyridin]-1-ium)) hexafluorophosphate(V)(1,1'-[Biphenyl-4,4'-diylbis(methylene)]bis(4,4'-bipyridinium) bis(hexafluorophosphate)) is a metal-organic framework (MOF).
    1,1''-([1,1'-Biphenyl]-4,4'-diylbis(methylene))bis(([4,4'-bipyridin]-1-ium)) hexafluorophosphate(V)
  • HY-W543741

    MOFs Others
    Ruthenium(2+),bis(2,2'-bipyridine-κN1,κN1')(4-ethenyl-4'-methyl-2,2'-bipyridine-κN1,κN1')-,(OC-6-33)-,hexafluorophosphate(1-)(1:2) is a metal-organic framework (MOF).
    Ruthenium(2+),bis2,2'-bipyridine-κN1,κN1'4-ethenyl-4'-methyl-2,2'-bipyridine-κN1,κN1'-,(OC-6-33)-,hexafluorophosphate(1-)(1:2)
  • HY-44650

    MOFs Others
    2,2',2'',2'''-(Porphyrin-5,10,15,20-tetrayl)tetrakis(1,3-diethyl-1H-imidazol-3-ium) hexafluorophosphate(V) is a metal-organic framework (MOF).
    2,2',2'',2'''-(Porphyrin-5,10,15,20-tetrayl)tetrakis(1,3-diethyl-1H-imidazol-3-ium) hexafluorophosphate(V)
  • HY-W543736

    MOFs Others
    Mono(4,4',4'',4'''-([1,1'-biphenyl]-3,3',5,5'-tetrayl)tetrakis(1-methylpyridin-1-ium))mono(hexafluorophosphate(V)) is a metal-organic framework (MOF).
    Mono(4,4',4'',4'''-([1,1'-biphenyl]-3,3',5,5'-tetrayl)tetrakis(1-methylpyridin-1-ium))monohexafluorophosphate(V)
  • HY-W543737

    MOFs Others
    Mono(4,4',4'',4'''-([1,1'-biphenyl]-3,3',5,5'-tetrayl)tetrakis(1-(4-(bromomethyl)benzyl)pyridin-1-ium))mono(hexafluorophosphate(V)) is a metal-organic framework (MOF).
    Mono(4,4',4'',4'''-([1,1'-biphenyl]-3,3',5,5'-tetrayl)tetrakis(1-(4-(bromomethyl)benzyl)pyridin-1-ium))monohexafluorophosphate(V)

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