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DOTA-NHS-ester hexafluorophosphate TFA

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DOTA-NHS-ester (hexafluorophosphate TFA)is a bifunctional chelator (Bifunctional Chelator; BFC) and a macrocyclic DOTA derivative used for tumor pre-targeting. DOTA-NHS-ester (hexafluorophosphate TFA) can be used for conjugation of peptides and radionuclides.

For research use only. We do not sell to patients.

  • CAS No.: 1823122-52-6
  • Formula: C20H31N5O10.C2HF3O2.F6P.H
  • Molecular Weight:761.48
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • DOTA-NHS-ester hexafluorophosphate TFA Chemical Structure
    DOTA-NHS-ester hexafluorophosphate TFA Chemical Structure
  • Experimental Validation Results for DOTA-NHS-ester hexafluorophosphate TFA
  • Experimental Validation Results for DOTA-NHS-ester hexafluorophosphate TFA
CAS No.: 1823122-52-6
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  • DOTA-NHS-ester hexafluorophosphate TFA Chemical Structure
    DOTA-NHS-ester hexafluorophosphate TFA Chemical Structure
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    DOTA-NHS-ester hexafluorophosphate TFA purchased from MedChemExpress. Usage Cited in: Adv Nanobiomed Res. 2023 Sep 3.

    Customer Validation
     PSP–NH2 was incubated with DOTA–NHS–ester for 1 h and conjugated with mPEG–NHS. Then, the particles were mixed with 64Cu (OAc)2 at 50 ℃ for 1 h to obtain the 64Cu-labelled PSP. PSP@Ab@PEG exhibited increased blood circulation in BALB/c mice with blood clearance half-life periods found to be 12 min.

  • 1/16

    DOTA-NHS-ester hexafluorophosphate TFA purchased from MedChemExpress. Usage Cited in: Adv Nanobiomed Res. 2023 Sep 3.

    Customer Validation
     PSP–NH2 was incubated with DOTA–NHS–ester for 1 h and conjugated with mPEG–NHS. Then, the particles were mixed with 64Cu (OAc)2 at 50 ℃ for 1 h to obtain the 64Cu-labelled PSP. More PSP–NH2 accumulated in the liver site while a lot more PSP@Ab@PEG accumulated in the spleen.

  • DOTA-NHS-ester hexafluorophosphate TFA