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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
33 Results for "
cell lifespan
" in MedChemExpress (MCE) Product Catalog:
Products (33)
33 Results for "cell lifespan" in MCE Product Catalog:
10
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Rosaceae Crataegus pinnatifida Bge. Plants Flavonoids Functional Molecules Research of Health Products Phenols Polyphenols Disease Research Fields Biflavones Cancer
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1 Cited Publications
Cat. No.: HY-N0723
CAS No.: 64809-67-2
Cat. No.: HY-P991488
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Cat. No.: HY-172371
CAS No.: 2414508-40-8
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Neurological Disease Metabolic Disease Inflammation/Immunology
Hypoxystat is an orally active hypoxia mimetic. HypoxyStat increases Hemoglobin’s oxygen affinity, limiting oxygen offloading to the tissues and inducing local tissue hypoxia. Hypoxystat reduces Iba1 + cells. HypoxyStat causes systemic hypoxia. Hypoxystat effectively rescues hyperglycemia in mouse models of type 1 and type 2 diabetes. HypoxyStat not only extends lifespan but also rescues key neuropathological and behavioral deficits in the premier mouse model of Leigh syndrome .
Cat. No.: HY-18676B
CAS No.: 1333146-24-9
Synonyms: OSU-T315 analog
ILK-IN-2 (OSU-T315 analog) is an oral PDK2 inhibitor and also an ILK inhibitor, with an IC50 of 0.6 μM. ILK-IN-2 induces cell autophagy and apoptosis, showing anti-tumor activity. ILK-IN-2 directly abolishes AKT activation by preventing AKT from translocating to lipid rafts, triggering Caspase-dependent apoptosis in chronic lymphocytic leukemia (CLL) and extending the lifespan in TCL1 mouse models .
Cat. No.: HY-P10861A
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Cat. No.: HY-P991736
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Cat. No.: HY-P11005
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Cat. No.: HY-P10861
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Synonyms: DEAE-dextran, MW 500000 hydrochloride, from bacterial (Leuconostoc mesenteroides); Diethylaminoethyl-dextran, MW 500000 hydrochloride
Cat. No.: HY-124089
CAS No.: 109001-03-8
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Eicosapentaenoyl ethanolamide, an omega-3 fatty acid, is one of N-acylethanolamines (NAEs). Eicosapentaenoyl ethanolamide is cannabinoid CB1/CB2 receptor agonist. Eicosapentaenoyl ethanolamide acts as a metabolic signal. Eicosapentaenoyl ethanolamide inhibits dietary restriction (DR)-induced lifespan extension in wild type animals and suppresses lifespan extension in a TOR pathway mutant .
Cat. No.: HY-N2342R
CAS No.: 37064-30-5
Synonyms: PCC1 (Standard)
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Cat. No.: HY-167711
CAS No.: 863589-28-0
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Sirtuin modulator 9 (Compound 214) is a sirtuin-modulating compound that may be used to increase lifespan of cells and in diseases related to aging, inflammation and cancer as well as diseases that would benefit from increased mitochondrial activity .
Cat. No.: HY-148322
CAS No.: 694469-31-3
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Infection Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
Sirtuin modulator 5 is a sirtuin modulating agent. Sirtuin modulator 5 can activate SIRT1 with a DC50 value of <50 μM. Sirtuin modulator 5 can be used for increasing the lifespan of a cell and used for the research of variety of diseases including, for example, diseases or disorders related to aging or stress, diabetes, obesity, neurodegenerative diseases, cardiovascular disease, blood clotting disorders, inflammation, cancer, and/or flushing as well as diseases or disorders that would benfit from increased mitochondrial activity .
Cat. No.: HY-Q49697
CAS No.: 708995-11-3
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Sirtuin modulator 3 (compound 129) is a N-phenyl benzamide derivative, acts as a sirtuin modulator .
Cat. No.: HY-169518
CAS No.: 332939-29-4
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TERT activator-2 (Compound 1030) is a telomerase reverse transcriptase (TERT) activator that can increase the expression of TERT in cells. TERT activator-2 can be used in telomere-related cell lifespan research .
Cat. No.: HY-155988
CAS No.: 476633-98-4
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Cardiovascular Disease Neurological Disease Metabolic Disease Cancer
Sirtuin modulator 6 (compound 262) increases the lifespan of a cell. Sirtuin modulator 6 can be used for study of diabetes, obesity, neurodegenerative diseases, cardiovascular disease, and so an extracted from patent WO2009064913A1 .
Duclauxin decreases proliferation of tumor cells in vitro and increases the lifespan of mice innoculated with Ehrlich ascitic tumor cells. Duclauxin (10-30 μg/mL) inhibits mitochondrial respiration of P-388 tumor cells and nucleic acid synthesis in cell culture of Ehrlich cancer, the lymphadenomas NK/LI and L 5178, and sarcoma 37. Duclauxin also inhibits growth of wheat coleoptile.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
