Cyanamide-¹⁵N₂

Cat. No.: HY-W720629: Data Sheet Handling Instructions
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Cyanamide-¹⁵N2 is the ¹⁵N-labeled Cyanamide (HY-Y0070). Cyanamide is a cell division and plant growth inhibitor, as well as an allelochemical derived from Vicia villosa. Cyanamide inhibits root growth and biomass accumulation in a dose-dependent manner by disrupting the formation of mitotic spindles and phragmoplast complexes, reducing the number of mitotic cells and blocking the cell cycle. The effects of Cyanamide are partially reversible after removal from low-concentration environments. Cyanamide is also a specific inhibitor of aldehyde dehydrogenase (ALDH). Although Cyanamide has no direct effect on tumor growth, it can significantly enhance the anti-tumor efficacy of Cyclophosphamide (HY-17420) at non-toxic doses by inhibiting the inactivation of Cyclophosphamide. Cyanamide enables Cyclophosphamide to exert equivalent therapeutic effects at lower doses, effectively inhibiting the growth of primary and metastatic tumors and prolonging the lifespan of tumor-bearing mice. Cyanamide is commonly used in studies related to ha-1 hepatoma and rls lymphosarcoma.

For research use only. We do not sell to patients.

Cyanamide-¹⁵N₂ Chemical Structure

CAS No. : 21420-37-1

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1 mg	Get quote 4 - 5 weeks 5 - 6 weeks 6 - 7 weeks 3 - 4 weeks	Estimated Time of Arrival: December 31
5 mg	Get quote 4 - 5 weeks 5 - 6 weeks 6 - 7 weeks 3 - 4 weeks	Estimated Time of Arrival: December 31
10 mg	Get quote 4 - 5 weeks 5 - 6 weeks 6 - 7 weeks 3 - 4 weeks	Estimated Time of Arrival: December 31
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Based on 1 publication(s) in Google Scholar

Other Forms of Cyanamide-¹⁵N₂:

Cyanamide In-stock

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Biological Activity
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Description	Cyanamide-¹⁵N2 is the ¹⁵N-labeled Cyanamide (HY-Y0070). Cyanamide is a cell division and plant growth inhibitor, as well as an allelochemical derived from Vicia villosa. Cyanamide inhibits root growth and biomass accumulation in a dose-dependent manner by disrupting the formation of mitotic spindles and phragmoplast complexes, reducing the number of mitotic cells and blocking the cell cycle. The effects of Cyanamide are partially reversible after removal from low-concentration environments. Cyanamide is also a specific inhibitor of aldehyde dehydrogenase (ALDH). Although Cyanamide has no direct effect on tumor growth, it can significantly enhance the anti-tumor efficacy of Cyclophosphamide (HY-17420) at non-toxic doses by inhibiting the inactivation of Cyclophosphamide. Cyanamide enables Cyclophosphamide to exert equivalent therapeutic effects at lower doses, effectively inhibiting the growth of primary and metastatic tumors and prolonging the lifespan of tumor-bearing mice. Cyanamide is commonly used in studies related to ha-1 hepatoma and rls lymphosarcoma^[1]^[2].
Application	1. This compound can be used as a tracer. 2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1]. MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Cyanamide-¹⁵N₂ Related Antibodies
Molecular Weight	44.03
Formula	CH₂¹⁵N₂
CAS No.	21420-37-1
Unlabeled CAS	420-04-2
SMILES	[15NH2]C#[15N]
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Data Sheet (262 KB) Handling Instructions (2659 KB)
References	[1]. Soltys D, et al. Cyanamide mode of action during inhibition of onion (Allium cepa L.) root growth involves disturbances in cell division and cytoskeleton formation. Planta. 2011;234(3):609-621. [2]. Kaledin V I, et al. Cyanamide promotes the antitumor effect of cyclophosphamide more than its toxic effect[C]//Doklady Biological Sciences. Springer Nature BV, 2008, 420(1): 195.