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chromogenic pNA substrate

" in MedChemExpress (MCE) Product Catalog:

50

Inhibitors & Agonists

7

Fluorescent Dyes

1

Biochemical Assay Reagents

47

Peptides

Cat. No. Product Name Target Research Area
  • HY-P2573
    Suc-AAPF-pNA
    2 Publications Verification

    Suc-Ala-Ala-Pro-Phe-pNA

    		 Peptides Others
    Suc-AAPF-pNA (Suc-Ala-Ala-Pro-Phe-pNA) is a chromogenic p-nitroanilide (pNA) substrate with the Km of 1.7 mM. Cleavage of Suc-AAPF-pNA releases 4-nitroaniline, which is yellow in colour and can be measured spectrophotometrically. Suc-AAPF-pNA can be used for the measurement of free and membrane-bound cathepsin G in human neutrophils .
  • HY-P2685
    MeOSuc-Ala-Ala-Pro-Val-pNA

    		Fluorescent Dye Others
    MeOSuc-Ala-Ala-Pro-Val-pNA is a sensitive chromogenic substrate for human leukocyte and porcine pancreatic elastase .
  • HY-123275A
    H-D-Phe-Pip-Arg-pNA hydrochloride
    1 Publications Verification

    S-2238 hydrochloride

    		 Fluorescent Dye Others
    H-D-Phe-Pip-Arg-pNA (S-2238) hydrochloride, a chromogenic substrate, is patterned after the N-terminal portion of the A alpha chain of fibrinogen, which is the natural substrate of thrombin. H-D-Phe-Pip-Arg-pNA hydrochloride is specific for thrombin and is used to measure antithrombin-heparin cofactor (AT-III). The AT-III assay using H-D-Phe-Pip-Arg-pNA hydrochloride is sensitive, accurate, and easy to perform .
  • HY-123275B
    H-D-Phe-Pip-Arg-pNA acetate
    1 Publications Verification

    S-2238 acetate

    		 Fluorescent Dye Others
    H-D-Phe-Pip-Arg-pNA (S-2238) acetate, a chromogenic substrate, is patterned after the N-terminal portion of the A alpha chain of fibrinogen, which is the natural substrate of thrombin. H-D-Phe-Pip-Arg-pNA acetate is specific for thrombin and is used to measure antithrombin-heparin cofactor (AT-III). The AT-III assay using H-D-Phe-Pip-Arg-pNA acetate is sensitive, accurate, and easy to perform .
  • HY-P3936
    Endotoxin Substrate

    		Fluorescent Dye Others
    Endotoxin Substrate (Boc-LGR-pNA) is a chromogenic substrate can be used in quantitative assays of endotoxin .
  • HY-131409
    D-Val-Leu-Lys-pNA dihydrochloride

    D-Val-Leu-Lys-p-itoailide dihydrochloride; D-VLK-pNA dihydrochloride; S 2251 dihydrochloride

    		 Fluorescent Dye Others
    D-Val-Leu-Lys-pNA (D-Val-Leu-Lys-p-nitroanilide) dihydrochloride is a chromogenic peptide substrate that serves as a characteristic substrate for plasmin and plasminogen. D-Val-Leu-Lys-pNA dihydrochloride acts as a sensitive substrate for the DFE27 serine protease derived from Bacillus subtilis DC27. Catalyzed by plasmin, D-Val-Leu-Lys-pNA dihydrochloride binds and hydrolyzes to release p-nitroaniline (pNA), which can be detected colorimetrically at 405 nm as a measure of fibrinolytic activity .
  • HY-P4202
    Suc-Ala-Glu-Pro-Phe-pNA

    Suc-AEPF-pNA

    		 Biochemical Assay Reagents Others
    Suc-Ala-Glu-Pro-Phe-pNA (Suc-AEPF-pNA) is a chromogenic substrate for the peptidyl-prolyl isomerase Pin1. Suc-Ala-Glu-Pro-Phe-pNA is used to evaluate the inhibitory effect of target compounds on Pin1, the catalytic activity of Pin1, and other related assays .
  • HY-P0021A
    D-Lys(Z)-Pro-Arg-pNA diacetate
    1 Publications Verification

    Spectrozyme PCa; Chromozym Pca diacetate

    		 Fluorescent Dye Others
    D-Lys(Z)-Pro-Arg-pNA diacetate is a chromogenic peptide substrate of activated protein C (APC) .
  • HY-137409
    Suc-AAA-pNA

    		Peptides Others
    Suc-AAA-pNA is a hydrolyzable peptide substrate. Suc-AAA-pNA serves as a chromogenic substrate for porcine pancreatic elastase, and undergoes hydrolysis via a virtual transition state with a minor physical step and a dominant chemical step, thereby forming a stable reactant state .
  • HY-P10094
    β-Ala-Gly-Arg-pNA

    		Fluorescent Dye Others
    β-Ala-Gly-Arg-pNA is a chromogenic substrate of thrombin with pNA a strong absorbance at 405 nm .
  • HY-P4460
    AAA-pNA

    		Ser/Thr Protease Cancer
    AAA-pNA is a chromogenic substrate of Tripeptidyl-peptidase II. AAA-pNA can be used to test Tripeptidyl-peptidase II activity .
  • HY-P4518
    Z-Val-Gly-Arg-pNA

    		Ser/Thr Protease Others
    Z-Val-Gly-Arg-pNA is a chromogenic substrate for urokinase. Z-Val-Gly-Arg-pNA can be used for determination of urokinase activity .
  • HY-P4517
    Z-Tyr-Lys-Arg-pNA

    		Peptides Others
    Z-Tyr-Lys-Arg-pNA is a chromogenic substrate. Z-Tyr-Lys-Arg-pNA can be used to detect the activity of subtilisin-type and yapsin-like proteases .
  • HY-P4453
    Boc-Ala-Ala-Asp-pNA

    		Caspase Cancer
    Boc-Ala-Ala-Asp-pNA is a chromogenic substrate of granzyme B. Boc-Ala-Ala-Asp-pNA can be used to test functional activity of granzyme B .
  • HY-P4516
    Z-Phe-Leu-Glu-pNA

    		Peptides Cancer
    Z-Phe-Leu-Glu-pNA is a chromogenic substrate for glutamyl endopeptidases. Z-Phe-Leu-Glu-pNA has been used as a synthetic substrate in the study of proteolytic enzymes, including trypsin treatment, subtilisin and chymotrypsin. Z-Phe-Leu-Glu-pNA plays an important role in hormone disorders such as prostate cancer and breast cancer .
  • HY-123275C
    H-D-Phe-Pip-Arg-pNA dihydrochloride

    S-2238 dihydrochloride

    		 Fluorescent Dye Others
    H-D-Phe-Pip-Arg-pNA (S-2238) dihydrochloride, a chromogenic substrate, is patterned after the N-terminal portion of the A alpha chain of fibrinogen, which is the natural substrate of thrombin. H-D-Phe-Pip-Arg-pNA dihydrochloride is specific for thrombin and is used to measure antithrombin-heparin cofactor (AT-III). The AT-III assay using H-D-Phe-Pip-Arg-pNA dihydrochloride is sensitive, accurate, and easy to perform .
  • HY-P4484
    Suc-AAPK-pNA

    		Biochemical Assay Reagents Others
    Suc-AAPK-pNA is a chromogenic substrate for the determination of serine/threonine kinase activity and enzyme kinetic parameters .
  • HY-P3126
    Suc-Ile-Glu(γ-pip)-Gly-Arg-pNA hydrochloride

    		Factor Xa Others
    Suc-Ile-Glu(γ-pip)-Gly-Arg-pNA hydrochloride is a factor Xa specific chromogenic substrate .
  • HY-P10145
    Ac-LEVD-pNA

    		Biochemical Assay Reagents Caspase Others
    Ac-LEVD-pNA is a chromogenic substrate for caspase-4 and can be used to detect caspase-4 activity .
  • HY-P4254
    H-Gly-Glu-pNA

    		PAI-1 Ser/Thr Protease Others
    H-Gly-Glu-pNA is a chromogenic peptide substrate that can be widely used in enzymatic analysis, including trypsin and urokinase-type plasminogen activator (uPA) .
  • HY-P4582
    Suc-Phe-Ala-Ala-Phe-pNA

    Suc-FAAF-pNA

    		 Ser/Thr Protease Others
    Suc-Phe-Ala-Ala-Phe-pNA (Suc-FAAF-pNA) is a chromogenic polypeptide substrate that can be used for the quantitative activity assay of intracellular subtilisin (ISP) and neutral metalloprotease (NPS) derived from Saccharomonospora canescens. Suc-Phe-Ala-Ala-Phe-pNA is hydrolyzed by the catalytic triad of mature proteases to release the chromophore pNA. Suc-Phe-Ala-Ala-Phe-pNA is applicable to enzymological studies .
  • HY-123275
    H-D-Phe-Pip-Arg-pNA

    S-2238

    		 Fluorescent Dye Others
    H-D-Phe-Pip-Arg-pNA (S-2238), a chromogenic substrate, is patterned after the N-terminal portion of the A alpha chain of fibrinogen, which is the natural substrate of thrombin. H-D-Phe-Pip-Arg-pNA is specific for thrombin and is used to measure antithrombin-heparin cofactor (AT-III). The AT-III assay using H-D-Phe-Pip-Arg-pNA is sensitive, accurate, and easy to perform .
  • HY-P4458
    Boc-QAR-pNA

    		Ser/Thr Protease Cancer
    Boc-QAR-pNA is a chromogenic substrate of trypsin. Boc-QAR-pNA can be used to test trypsin activity .
  • HY-P4482
    Suc-AAPE-pNA

    		Bacterial Infection
    Suc-AAPE-pNA is a chromogenic substrate of glutamyl endopeptidase. Suc-AAPE-pNA can be used to test glutamyl endopeptidase activity .
  • HY-P4470
    Phe-Pro-Ala-pNA

    		Ser/Thr Protease Cancer
    Phe-Pro-Ala-pNA is a chromogenic substrate of tripeptidyl peptidase. Phe-Pro-Ala-pNA can be used to test tripeptidyl peptidase activity .
  • HY-P4464
    Ala-Phe-Pro-pNA

    		Ser/Thr Protease Cancer
    Ala-Phe-Pro-pNA is a chromogenic substrate of tripeptidyl peptidase. Ala-Phe-Pro-pNA can be used to test tripeptidyl peptidase activity .
  • HY-P5027
    Cbz-Lys-Arg-pNA

    		Ser/Thr Protease Kallikrein Factor Xa Thrombin Cardiovascular Disease
    Cbz-Lys-Arg-pNA is a peptide substrate containing pNA as the chromogenic group. Cbz-Lys-Arg-pNA is widely used in enzymatic analysis, including thrombin, plasmin, factor Xa and Kallikrein .
  • HY-P4464A
    Ala-Phe-Pro-pNA TFA

    		Ser/Thr Protease Cancer
    Ala-Phe-Pro-pNA TFA is a chromogenic substrate of tripeptidyl peptidase. Ala-Phe-Pro-pNA TFA can be used to test tripeptidyl peptidase activity .
  • HY-P6027A
    H-D-CHA-Ala-Arg-pNA diacetate

    		Fluorescent Dye Others
    H-D-CHA-Ala-Arg-pNA diacetate is the diacetate form of H-D-CHA-Ala-Arg-pNA (HY-P6027). H-D-CHA-Ala-Arg-pNA diacetate is a chromogenic substrate for the amidolytic assay .
  • HY-126809A
    Bz-Pro-Phe-Arg-pNA hydrochloride

    Bz-PFR-pNA hydrochloride

    		 Factor Xa Others
    Bz-Pro-Phe-Arg-pNA (Bz-PFR-pNA) hydrochloride is a chromogenic peptide substrate for plasma and glandular Kallikrein, cysteine proteinase (Cruzipain) and Trypsin. Bz-Pro-Phe-Arg-pNA hydrochloride can be used in Factor XII assay .
  • HY-P4039
    Ac-EEVVAC-pNA

    		HCV Protease Infection
    Ac-EEVVAC-pNA is a chromogenic substrate for a continuous spectrophotometric assay of HCV NS3 protease. The sequence EEVVAC is derived from the 5A-5B cleavage junction of the HCV polyprotein .
  • HY-P10448
    Boc-Leu-Gly-Arg-pNA acetate

    Boc-LGR-pNA acetate

    		 Fluorescent Dye Others
    Boc-Leu-Gly-Arg-pNA is a chromogenic synthetic substrate .
  • HY-P11392
    Ac-IEAR-pNA

    		Cholinesterase (ChE) Biochemical Assay Reagents Others
    Ac-IEAR-pNA is the chromogenic substrate for quantifying endotoxin levels. Ac-IEAR-pNA is cleaved by HuBChE to produce p-nitroaniline product .
  • HY-137798
    Chromozym PL

    		Fluorescent Dye Others
    Chromozym PL is a chromogenic substrate for plasmin, and the enzymatic reaction can be carried out in 0.1mL Tris-HCl buffer (50 mM, pH 7.8). 100 μM Chromozym PL was dissolved and prepared. After adding the hydrolase, the generation of p-nitroaniline (pNA) at 405 nm was continuously observed, and the hydrolysis products were calculated .
  • HY-P10083
    Ac-VQVD-pNA

    		Fluorescent Dye Others
    Ac-VQVD-pNA is a chromogenic substrate of caspase 3 .
  • HY-P6027
    H-D-CHA-Ala-Arg-pNA

    		Thrombin Others
    H-D-CHA-Ala-Arg-pNA is a chromogenic substrate for the amidolytic assay .
  • HY-138152
    Z-D-Arg-Gly-Arg-pNA dihydrochloride

    Benzyl-D-Arg-Gly-Arg-pNA dihydrochloride

    		 Fluorescent Dye Others
    Z-D-Arg-Gly-Arg-pNA dihydrochloride is a hydrolytic chromogenic plasmin substrate .
  • HY-P4475
    Sar-Pro-Arg-pNA

    		Thrombin Cardiovascular Disease
    Sar-Pro-Arg-pNA is a chromogenic substrate of α-thrombin. Sar-Pro-Arg-pNA can be used to test α-thrombin activity .
  • HY-126809
    Bz-Pro-Phe-Arg-pNA

    Bz-PFR-pNA

    		 Kallikrein Ser/Thr Protease Parasite Factor Xa Others
    Bz-Pro-Phe-Arg-pNA (Bz-PFR-pNA) is a chromogenic peptide substrate for plasma and glandular Kallikrein, cysteine proteinase (Cruzipain) and Trypsin. Bz-Pro-Phe-Arg-pNA can be used in Factor XII assay .
  • HY-P0021
    D-Lys(Z)-Pro-Arg-pNA

    Chromozym Pca

    		 Fluorescent Dye Others
    D-Lys(Z)-Pro-Arg-pNA (Chromozym Pca) is a chromogenic peptide substrate of activated protein C (APC) .
  • HY-P10005
    D-Val-Gly-Arg-pNA

    		Ser/Thr Protease Plasminogen/Plasmin Cardiovascular Disease
    D-Val-Gly-Arg-pNA is a chromogenic substrate of TPA (tissue plasminogen activator). D-Val-Gly-Arg-pNA can be used to detect the amidolytic activity of TPA I and TPA II .
  • HY-P4491
    Suc-Leu-Leu-Val-Tyr-pNA

    		Peptides Others
    Suc-Leu-Leu-Val-Tyr-pNA is a chymotrypsin-like chromogenic substrate that can be used to detect chymotrypsin enzymatic activity .
  • HY-P4202A
    Suc-Ala-Glu-Pro-Phe-pNA TFA

    Suc-AEPF-pNA TFA

    		 Biochemical Assay Reagents Others
    Suc-Ala-Glu-Pro-Phe-pNA (Suc-AEPF-pNA ) TFA is a chromogenic substrate for the peptidylprolyl isomerase Pin1. Suc-Ala-Glu-Pro-Phe-pNA TFA can be used to evaluate the inhibitory effect of the target compound on Pin1, and catalytic activity of Pin1, etc .
  • HY-P10668
    Ac-EVKKQR-pNA

    		Dengue Virus Flavivirus Infection
    Ac-EVKKQR-pNA is a competitive chromogenic para-nitroanilide substrate corresponding to the P6-P1 segment amino-terminal to the NS2B-NS3 cleavage site but with a more reactive, hydrolytically cleavable, para-nitroanilide at the P1’ position. Ac-EVKKQR-pNA is promising for research of dengue 2 virus and flavivirus virus infection .
  • HY-P3480
    H-Trp-Phe-Tyr-Ser(PO3H2)-Pro-Arg-pNA

    		Fluorescent Dye Others
    H-Trp-Phe-Tyr-Ser(PO3H2)-Pro-Arg-pNA is a chromogenic substrate for Pin1. Pin1 is an essential and conserved mitotic peptidyl-prolyl isomerase, and can recognize the phosphoserine-proline bonds present in mitotic phosphoproteins .
  • HY-P10005A
    D-Val-Gly-Arg-pNA acetate

    		Ser/Thr Protease Plasminogen/Plasmin Cardiovascular Disease
    D-Val-Gly-Arg-pNA acetate is a chromogenic substrate of TPA (tissue plasminogen activator). D-Val-Gly-Arg-pNA can be used to detect the amidolytic activity of TPA I and TPA II .
  • HY-168378A
    D-Val-Leu-Lys-pNA acetate

    S-2251 acetate

    		 Fluorescent Dye Others
    D-Val-Leu-Lys-pNA acetate (S-2251 acetate) is a chromogenic peptide substrate that serves as a characteristic substrate for plasmin and plasminogen. D-Val-Leu-Lys-pNA acetate acts as a sensitive substrate for the DFE27 serine protease derived from Bacillus subtilis DC27. Catalyzed by plasmin, D-Val-Leu-Lys-pNA acetate binds and hydrolyzes to release p-nitroaniline (pNA), which can be detected colorimetrically at 405 nm as a measure of fibrinolytic activity .

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