37 Results for "

herpes simplex virus type-1

" in MedChemExpress (MCE) Product Catalog:
Products (37)

37 Results for "herpes simplex virus type-1" in MCE Product Catalog:

7
7 Publications Verification
Cat. No.: HY-15303
CAS No.: 348086-71-5
Purity:  99.94%
Synonyms: AIC316; BAY 57-1293
Target:  

DNA/RNA Synthesis HSV

Research Areas:  

Infection

Pritelivir (AIC316), an inhibitor of the viral helicase-primase complex, exhibits antiviral activity in vitro and in animal models of herpes simplex virus (HSV) infection. Pritelivir is active against herpes simplex virus types 1 and 2 (HSV-1 and HSV-2) with the IC50 of 0.02 μM against HSV1-2 .
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7
7 Publications Verification
Cat. No.: HY-15303A
CAS No.: 1428333-96-3
Purity:  99.51%
Synonyms: AIC316 mesylate; BAY 57-1293 mesylate
Target:  

DNA/RNA Synthesis HSV

Research Areas:  

Infection

Pritelivir mesylate (BAY 57-1293 mesylate), an inhibitor of the viral helicase-primase complex, exhibits antiviral activity in vitro and in animal models of herpes simplex virus (HSV) infection. Pritelivir mesylate is active against herpes simplex virus types 1 and 2 (HSV-1 and HSV-2) with the IC50 of 0.02 μM against HSV1-2 .
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7
7 Publications Verification
Cat. No.: HY-15303B
CAS No.: 1428321-10-1
Purity:  99.51%
Synonyms: AIC316 mesylate hydrate; BAY 57-1293 mesylate hydrate
Target:  

DNA/RNA Synthesis HSV

Research Areas:  

Infection

Pritelivir mesylate hydrate (BAY 57-1293 mesylate hydrate), an inhibitor of the viral helicase-primase complex, exhibits antiviral activity in vitro and in animal models of herpes simplex virus (HSV) infection. Pritelivir mesylate hydrate is active against herpes simplex virus types 1 and 2 (HSV-1 and HSV-2) with the IC50 of 0.02 μM against HSV1-2 .
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4
4 Cited Publications
Cat. No.: HY-N0772
CAS No.: 24699-16-9
Isomangiferin is an orally active xanthone C-glucoside, and its chemical structure is similar to Mangiferin (HY-N0290). Isomangiferin is an effective VEGFR-2 kinase inhibitor, which can induces cell apoptosis, inhibit the growth, metastasis and angiogenesis of breast cancer. Isomangiferin exerts anti-inflammatory effects by inhibiting the HMGB1/NLRP3/NF-κB signaling pathway, thereby improving the renal function indicators of diabetic mice. Isomangiferin exhibits inhibitory effects on various bacteria and herpes simplex virus type 1 (HSV-1). Isomangiferin promotes the migration and osteogenic differentiation of bone marrow mesenchymal stem cells (BMSCs) and reduces cell apoptosis and the production of ROS by activating the AMPK/ACC pathway, thereby facilitating fracture healing .
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1
1 Cited Publications
Cat. No.: HY-N2004
CAS No.: 124-76-5
Synonyms: (±)-Isoborneol
Isoborneol ((±)-Isoborneol) is a monoterpenoid alcohol present in the essential oils of numerous medicinal plants and has antioxidant and antiviral properties. Isoborneol is a potent inhibitor of herpes simplex virus type 1 (HSV-1) .
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1
1 Cited Publications
Cat. No.: HY-U00124B
CAS No.: 41544-24-5
Target:  

HSV

Research Areas:  

Infection

Tromantadine hydrochloride, an Amantadine derivative with antiherpetic activity, inhibits herpes simplex virus type 1 (HSV-1) and HSV-2 replication .
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Cat. No.: HY-160222
Target:  

HSV STING IFNAR NF-κB

Research Areas:  

Infection

HSV-60mer sodium is a 60 bp double-stranded DNA oligonucleotide derived from the HSV-1 genome, and also an IFNβ inducer. HSV-60mer sodium colocalizes with endogenous cytoplasmic IFI16 in immune cells. HSV-60mer sodium activates the transcription factors IRF3 and NF-κB, induces the production of proinflammatory cytokines, and inhibits HSV-1 replication in immune cells. HSV-60mer sodium can be used in studies related to herpes simplex virus type 1 infection .
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Cat. No.: HY-W002008
CAS No.: 480-68-2
Target:  

HSV

Research Areas:  

Infection Inflammation/Immunology

5-Nitrobarbituric acid is a herpes simplex virus type-1 (HSV-1) inhibitor (IC50=1.7 μM) .
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Cat. No.: HY-N1060
CAS No.: 40456-50-6
Yatein is a lignan isolated from A. chilensis, with antiproliferative activity . Yatein suppresses herpes simplex virus type 1 (HSV-1 ) replication by interruption the immediate-early gene expression .
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Cat. No.: HY-N3395
CAS No.: 152464-78-3
Leachianone G is an antiviral flavonoid from the root bark of Morus alba L. Leachianone G shows potent antiviral activity against herpes simplex type 1 virus (HSV-1) with an IC50 value of 1.6 μg/mL .
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Cat. No.: HY-P10868
CAS No.: 2056232-82-5
Synonyms: RLS-0071
Pegtarazimod (RLS-0071) is a dual-target anti-inflammatory peptide that exerts its effects by simultaneously regulating the complement system and neutrophil-associated inflammatory pathways. Pegtarazimod reduces ROS production both in vitro and in vivo, and decreases the level of neutrophil elastase, a marker of neutrophil extracellular traps (NETs), in vivo, thereby alleviating inflammatory responses. Pegtarazimod significantly improves the survival rate of mice in multiple in vivo models of acute graft-versus-host disease (aGVHD). Pegtarazimod inhibits the activation of the C1 complex, reduces the herpes zoster-like spread of herpes simplex virus type 1 skin infection, and improves the survival rate of infected mice . Pegtarazimod can be used in research related to acute graft-versus-host disease, acute pulmonary diseases, and skin herpes simplex virus type 1 infection .
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Cat. No.: HY-U00224
CAS No.: 114778-60-8
Target:  

EBV VZV HSV

Research Areas:  

Infection

BRL44385 is a potent and selective inhibitor of the replication of herpes simplex virus types 1 and 2 (HSV-1 and HSV2), varicella zoster virus (VZV) and Epstein-Barr virus (EBV).
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Cat. No.: HY-U00124
CAS No.: 53783-83-8
Target:  

HSV

Research Areas:  

Infection

Tromantadine hydrochloride, an Amantadine derivative with antiherpetic activity, inhibits herpes simplex virus type 1 (HSV-1) and HSV-2 replication .
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Cat. No.: HY-123211
CAS No.: 273388-09-3
Target:  

HSV

Research Areas:  

Infection

WAY-150138 inhibits replication of herpes simplex virus type 1 (HSV-1) that acts by preventing the incorporation of DNA-packaging proteins into capsids as they are assembled
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Cat. No.: HY-15303AR
CAS No.: 1428333-96-3
Synonyms: AIC316 mesylate (Standard); BAY 57-1293 mesylate (Standard)
Target:  

HSV Reference Standards

Research Areas:  

Infection

Pritelivir (mesylate) (Standard) is the analytical standard of Pritelivir (mesylate). This product is intended for research and analytical applications. Pritelivir mesylate (BAY 57-1293 mesylate), an inhibitor of the viral helicase-primase complex, exhibits antiviral activity in vitro and in animal models of herpes simplex virus (HSV) infection. Pritelivir mesylate is active against herpes simplex virus types 1 and 2 (HSV-1 and HSV-2) with the IC50 of 0.02 μM against HSV1-2 .
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Cat. No.: HY-15303R
CAS No.: 348086-71-5
Synonyms: AIC316 (Standard); BAY 57-1293 (Standard)
Target:  

HSV Reference Standards

Research Areas:  

Infection

Pritelivir (Standard) is the analytical standard of Pritelivir. This product is intended for research and analytical applications. Pritelivir (AIC316), an inhibitor of the viral helicase-primase complex, exhibits antiviral activity in vitro and in animal models of herpes simplex virus (HSV) infection. Pritelivir is active against herpes simplex virus types 1 and 2 (HSV-1 and HSV-2) with the IC50 of 0.02 μM against HSV1-2 .
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Cat. No.: HY-177638
CAS No.: 141442-28-6
Target:  

HSV

Research Areas:  

Infection

ISIS 1082 is an antisense oligonucleotide targeted to the translation initiation codon of herpes simplex virus (HSV) type 1 and 2 virion capsid protein. It has been shown to inhibit HSV-1 replication in vitro
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Cat. No.: HY-N14564
CAS No.: 142382-46-5
Category:  

Microorganisms Antibiotics

Target:  

Antibiotic HSV

Cycloviracin B2 is an antibiotic with antiviral activity. Cycloviracin B2 has a strong inhibitory activity against herpes simplex virus type 1 (HSV-1) .
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Cat. No.: HY-176163
Target:  

HSV

Research Areas:  

Infection

HSV-1-IN-2 (compound 5i) is a potent Herpes simplex virus type 1 (HSV-1) inhibitor with an EC50 of 1.95 μM. HSV-1-IN-2 inhibits apoptosis and improves herpes encephalitis model mouse survival .
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Cat. No.: HY-177638A
Target:  

HSV

Research Areas:  

Infection

ISIS 1082 sodium is an antisense oligonucleotide targeted to the translation initiation codon of herpes simplex virus (HSV) type 1 and 2 virion capsid protein. It has been shown to inhibit HSV-1 replication in vitro
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