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Cat. No.: HY-123211

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WAY-150138

WAY-150138 inhibits replication of herpes simplex virus type 1 (HSV-1) that acts by preventing the incorporation of DNA-packaging proteins into capsids as they are assembled

For research use only. We do not sell to patients.

CAS No.: 273388-09-3
Formula: C₂₂H₁₈Cl₂FN₃O₃S
Molecular Weight:494.37

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

WAY-150138 Chemical Structure

CAS No.: 273388-09-3

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

WAY-150138 inhibits replication of herpes simplex virus type 1 (HSV-1) that acts by preventing the incorporation of DNA-packaging proteins into capsids as they are assembled^[1]^[2]

IC₅₀ & Target

HSV-1

0.2 μg/mL (IC₅₀)

HSV-2

6.8 μg/mL (IC₅₀)

All HSV Isoforms :

Chemical Information

CAS No. 273388-09-3
Molecular Weight 494.37
Formula C₂₂H₁₈Cl₂FN₃O₃S
SMILES

O=C(C1=CC=CC=C1F)NC2=CC=C(C(Cl)=C2)NC(NC3=CC(Cl)=C(C=C3OC)OC)=S
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. William W. Newcomb, et al. Inhibition of Herpes Simplex Virus Replication by WAY-150138: Assembly of Capsids Depleted of the Portal and Terminase Proteins Involved in DNA Encapsidation. 2002 Oct; 76(19): 10084–10088. [Content Brief]

[2]. M van Zeijl, et al. Novel class of thiourea compounds that inhibit herpes simplex virus type 1 DNA cleavage and encapsidation: resistance maps to the UL6 gene. J Virol. 2000 Oct;74(19):9054-61. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References

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WAY-150138

Cyclopropavir

Isoborneol

Tromantadine hydrochloride

Stearyl gallate

Vidarabine monohydrate

B220

Pritelivir mesylate

Pritelivir mesylate hydrate

Tromantadine

Isoborneol (Standard)

Vidarabine monohydrate (Standard)

Pritelivir mesylate (Standard)

All HSV Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

WAY-150138

Cyclopropavir

Isoborneol

Tromantadine hydrochloride

Stearyl gallate

Vidarabine monohydrate

B220

Pritelivir mesylate

Pritelivir mesylate hydrate

Tromantadine

Isoborneol (Standard)

Vidarabine monohydrate (Standard)

Pritelivir mesylate (Standard)

All HSV Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

WAY-150138 Related Classifications

HY-123211 Related Classifications