WAY-150138
WAY-150138 inhibits replication of herpes simplex virus type 1 (HSV-1) that acts by preventing the incorporation of DNA-packaging proteins into capsids as they are assembled
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- CAS No.: 273388-09-3
- 화학식: C22H18Cl2FN3O3S
- 분자량:494.37
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- 순도&문서
- References
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Help & FAQs
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Pritelivir mesylate (Standard)
Biological Activity
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HSV-1 0.2 μg/mL (IC50) |
HSV-2 6.8 μg/mL (IC50) |
Chemical Information
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CAS No. 273388-09-3
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분자량 494.37
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화학식 C22H18Cl2FN3O3S
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SMILES
O=C(C1=CC=CC=C1F)NC2=CC=C(C(Cl)=C2)NC(NC3=CC(Cl)=C(C=C3OC)OC)=S
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
[1]. William W. Newcomb, et al. Inhibition of Herpes Simplex Virus Replication by WAY-150138: Assembly of Capsids Depleted of the Portal and Terminase Proteins Involved in DNA Encapsidation. 2002 Oct; 76(19): 10084–10088. [Content Brief]
[2]. M van Zeijl, et al. Novel class of thiourea compounds that inhibit herpes simplex virus type 1 DNA cleavage and encapsidation: resistance maps to the UL6 gene. J Virol. 2000 Oct;74(19):9054-61. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
WAY-150138 Related Classifications
HY-123211 Related Classifications
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