1. Anti-infection
  2. HSV
  3. Tromantadine hydrochloride

Tromantadine hydrochloride 

Cat. No.: HY-U00124B
Handling Instructions

Tromantadine hydrochloride, an Amantadine derivative with antiherpetic activity, inhibits herpes simplex virus type 1 (HSV-1) and HSV-2 replication.

For research use only. We do not sell to patients.

Tromantadine hydrochloride Chemical Structure

Tromantadine hydrochloride Chemical Structure

CAS No. : 41544-24-5

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Description

Tromantadine hydrochloride, an Amantadine derivative with antiherpetic activity, inhibits herpes simplex virus type 1 (HSV-1) and HSV-2 replication[1].

IC50 & Target[1]

HSV-1

 

HSV-2

 

In Vitro

Treatment of the cells with 10 to 50μg of Tromantadine reduces HSV-induced cytopathic effect. Treatment with 100 to 500μg of Tromantadine inhibits herpes simplex virus-induced cytopathic effect and reduces virus production. Complete inhibition of virus production is observed with treatments of 500μg to 1 mg. The antiherpetic activity of Tromantadine is dependent upon the viral inoculum size and the time of addition of the compound with respect to infection[1].

Molecular Weight

316.87

Formula

C₁₆H₂₉ClN₂O₂

CAS No.

41544-24-5

SMILES

[H]Cl.O=C(COCCN(C)C)NC1(C[[email protected]](C2)C3)C[[email protected]]3C[[email protected]]2C1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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Keywords:

TromantadineHSVHerpes simplex virusHSV-1HSV-2replicationvirusantiherpeticinfectioncytopathictoxicityInhibitorinhibitorinhibit

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Tromantadine hydrochloride
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HY-U00124B
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