2. Anti-infection
  3. HSV
  4. BVDU 5′-Triphosphate ammonium

BVDU 5′-Triphosphate ammonium  (Synonyms: (E)-5-(2-Bromovinyl)-dUTP ammonium; BVdUTP ammonium)

Cat. No.: HY-W747737A Purity: ≥98.0%
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BVDU 5′-Triphosphate ammonium is an antivirus agent with 5′-Triphosphate label, targeting viral DNA polymerase. BVDU 5′-Triphosphate ammonium shows excellent selectivity against varicella-zoster virus (VZV) and herpes simplex virus type 1 (HSV-1), due to a specific phosphorylation by the virus-encoded thymidine kinase.

For research use only. We do not sell to patients.

BVDU 5′-Triphosphate ammonium Chemical Structure

BVDU 5′-Triphosphate ammonium Chemical Structure

Size Price Stock Quantity
5 mg USD 300 In-stock
10 mg USD 480 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of BVDU 5′-Triphosphate ammonium:

BVDU 5′-Triphosphate ammonium Related Antibodies

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Description

BVDU 5′-Triphosphate ammonium is an antivirus agent with 5′-Triphosphate label, targeting viral DNA polymerase. BVDU 5′-Triphosphate ammonium shows excellent selectivity against varicella-zoster virus (VZV) and herpes simplex virus type 1 (HSV-1), due to a specific phosphorylation by the virus-encoded thymidine kinase.

Molecular Weight

590.11

Formula

C11H19BrN3O14P3
Appearance

Solid

Color

White to off-white

SMILES

OP(OP(OP(O)(OC[C@@H]1[C@@H](O)C[C@H](N2C(NC(C(/C=C/Br)=C2)=O)=O)O1)=O)(O)=O)(O)=O.N
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Room temperature in continental US; may vary elsewhere.
Storage

-20°C, stored under nitrogen, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture)

Solvent & Solubility
In Vitro: 

H2O : 250 mg/mL (423.65 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.6946 mL 8.4730 mL 16.9460 mL
5 mM 0.3389 mL 1.6946 mL 3.3892 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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(per animal)

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Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 1.6946 mL 8.4730 mL 16.9460 mL 42.3650 mL
5 mM 0.3389 mL 1.6946 mL 3.3892 mL 8.4730 mL
10 mM 0.1695 mL 0.8473 mL 1.6946 mL 4.2365 mL
15 mM 0.1130 mL 0.5649 mL 1.1297 mL 2.8243 mL
20 mM 0.0847 mL 0.4236 mL 0.8473 mL 2.1182 mL
25 mM 0.0678 mL 0.3389 mL 0.6778 mL 1.6946 mL
30 mM 0.0565 mL 0.2824 mL 0.5649 mL 1.4122 mL
40 mM 0.0424 mL 0.2118 mL 0.4236 mL 1.0591 mL
50 mM 0.0339 mL 0.1695 mL 0.3389 mL 0.8473 mL
60 mM 0.0282 mL 0.1412 mL 0.2824 mL 0.7061 mL
80 mM 0.0212 mL 0.1059 mL 0.2118 mL 0.5296 mL
100 mM 0.0169 mL 0.0847 mL 0.1695 mL 0.4236 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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BVDU 5′-Triphosphate ammonium Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

BVDU 5′-Triphosphate(E)-5-(2-Bromovinyl)-dUTPBVdUTPHSVHerpes simplex virusInhibitorinhibitorinhibit

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