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sugar donor

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29

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6

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14

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4

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3

Click Chemistry

2

Oligonucleotides

Cat. No. Nombre del producto Target Áreas de investigación Chemical Structure
  • HY-145934
    UDP-GalNAz disodium
    1 Publications Verification

    UDP-N-azidoacetylgalactosamine disodium

    Biochemical Assay Reagents OGT Glycosidase Metabolic Disease
    UDP-GalNAz (UDP-N-azidoacetylgalactosamine) disodium is the analogue of UDP-GalNAc disodium (HY-114365). UDP-GalNAc disodium is the donor substrate of many N-acetylgalactosaminyltransferases, enzymes which transfer GalNAc from the nucleotide sugar to a saccharide or peptide acceptor. UDP-GalNAz disodium is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups .
    UDP-GalNAz disodium
  • HY-N11287A
    UDP-xylose disodium
    2 Publications Verification

    Endogenous Metabolite Others
    UDP-xylose disodium is an endogenous sugar nucleotide and a catalytic substrate of UDP-xylose disodium synthase (UXS). UDP-xylose disodium is a sugar donor for the synthesis of glycoproteins, polysaccharides, various metabolites and oligosaccharides in plants, vertebrates and fungi, and participates in the synthesis of proteoglycans as a glycosyl donor. UDP-xylose disodium participates in the regulation of the synthesis of extracellular matrix components and can be used to study the mechanism of proteoglycan biosynthesis in glycobiology and related diseases (such as connective tissue diseases)[1][2].
    UDP-xylose disodium
  • HY-112942A
    CMP-Sialic acid sodium salt
    4 Publications Verification

    CMP-Neu5Ac sodium salt

    Endogenous Metabolite Metabolic Disease
    CMP-Sialic acid (CMP-Neu5Ac) sodium salt is an allosteric inhibitor of UDP-GlcNAc 2-epimerase. CMP-Sialic acid sodium salt provides a substrate for Golgi sialyltransferases. CMP-Sialic acid sodium salt is an important sugar nucleotide for biosynthesis of sialic acid and its conjugates .
    CMP-Sialic acid sodium salt
  • HY-N2024
    Maltose
    1 Publications Verification

    Endogenous Metabolite Glycosidase Metabolic Disease
    Maltose is a disaccharide composed of two glucose molecules linked together. Maltose is an endogenous metabolic product in plants, yeast, or bacteria, and it participates in carbon source storage and metabolism. Maltose is a key core metabolite and main transport form in the temporary starch degradation, carbon output, and subsequent sucrose synthesis metabolism of the night chloroplast. In X. dendrorhous, maltose can act as a sugar donor and is converted into isomaltulose by α-glucosidase). Maltose can act as a osmotic agent, supporting continuous capillary ultrafiltration and preventing severe metabolic disorders .
    Maltose
  • HY-114364
    UDP-Galactose disodium
    4 Publications Verification

    Endogenous Metabolite P2Y Receptor Metabolic Disease
    UDP-Galactose disodium is a monosaccharide and a key glycosyl donor molecule in cells that participates in nucleotide sugar metabolism. UDP-Galactose disodium is the natural agonist of the P2Y14 receptor coupled to Gi proteins in the immune system (IC50 = 0.67 μM, hP2Y14). UDP-Galactose disodium can be used to study cell signal transduction and substance metabolism .
    UDP-Galactose disodium
  • HY-114365
    UDP-GalNAc disodium
    1 Publications Verification

    UDP-N-acetyl-D-galactosamine disodium

    Endogenous Metabolite Metabolic Disease Cancer
    UDP-GalNAc (UDP-N-acetyl-D-galactosamine) disodium is a sugar nucleotide and a substrate for EpsC115. EpsC115 is a mutant with N-terminal residues 1-115 deleted from the exopolymeric substance (EPS). UDP-GalNAc disodium is a donor substrate for many N-acetylgalactosaminyltransferases, which transfer GalNAc from nucleotide sugars to sugar or peptide acceptors. UDP-GalNAc disodium provides a sugar group donor for glycosylation reactions. UDP-GalNAc disodium can be used in cancer research, such as colorectal and breast cancer .
    UDP-GalNAc disodium
  • HY-N10573
    UDP-rhamnose
    2 Publications Verification

    Drug Derivative Fungal Infection
    UDP-rhamnose, the activated form of Rhamnose (HY-N1420) in fungi, is a key precursor for fungi to synthesize rhamnose-containing glycans. UDP-rhamnose can be used in the research on the treatment of fungal diseases .
    UDP-rhamnose
  • HY-N2024A
    Maltose monohydrate
    1 Publications Verification

    Endogenous Metabolite Glycosidase Metabolic Disease
    Maltose monohydrate is a disaccharide composed of two glucose molecules linked together. Maltose monohydrate is an endogenous metabolic product in plants, yeast, or bacteria, and it participates in carbon source storage and metabolism. Maltose monohydrate is a key core metabolite and main transport form in the temporary starch degradation, carbon output, and subsequent sucrose synthesis metabolism of the night chloroplast. In X. dendrorhous, maltose can act as a sugar donor and is converted into isomaltulose by α-glucosidase. Maltose monohydrate can act as a osmotic agent, supporting continuous capillary ultrafiltration and preventing severe metabolic disorders .
    Maltose monohydrate
  • HY-145934A

    OGT Biochemical Assay Reagents Glycosidase Metabolic Disease
    UDP-GlcNAz disodium is the analogue of UDP-GlcNAc disodium (HY-112174). UDP-GlcNAc disodium is the donor substrate of many N-acetylgalactosaminyltransferases, enzymes which transfer GlcNAc from the nucleotide sugar to a saccharide or peptide acceptor. UDP-GlcNAc disodium is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups .
    UDP-GlcNAz disodium
  • HY-N2024AS1

    Isotope-Labeled Compounds Endogenous Metabolite Glycosidase Metabolic Disease
    Maltose monohydrate- 13C12 is the 13C labeled isotope of Maltose monohydrate. Maltose monohydrate is a disaccharide composed of two glucose molecules linked together. Maltose monohydrate is an endogenous metabolic product in plants, yeast, or bacteria, and it participates in carbon source storage and metabolism. Maltose monohydrate is a key core metabolite and main transport form in the temporary starch degradation, carbon output, and subsequent sucrose synthesis metabolism of the night chloroplast. In X. dendrorhous, maltose can act as a sugar donor and is converted into isomaltulose by α-glucosidase. Maltose monohydrate can act as a osmotic agent, supporting continuous capillary ultrafiltration and preventing severe metabolic disorders.
    Maltose-13C12 monohydrate
  • HY-N11287

    Endogenous Metabolite Others
    UDP-xylose is an endogenous sugar nucleotide and a catalytic substrate of UDP-xylose synthase (UXS). UDP-xylose is a sugar donor for the synthesis of glycoproteins, polysaccharides, various metabolites and oligosaccharides in plants, vertebrates and fungi, and participates in the synthesis of proteoglycans as a glycosyl donor. UDP-xylose participates in the regulation of the synthesis of extracellular matrix components and can be used to study the mechanism of proteoglycan biosynthesis in glycobiology and related diseases (such as connective tissue diseases)[1][2].
    UDP-xylose
  • HY-112942

    CMP-Neu5Ac

    Endogenous Metabolite Metabolic Disease
    CMP-Sialic acid (CMP-Neu5Ac) is an allosteric inhibitor of UDP-GlcNAc 2-epimerase. CMP-Sialic acid provides a substrate for Golgi sialyltransferases. CMP-Sialic acid is an important sugar nucleotide for biosynthesis of sialic acid and its conjugates .
    CMP-Sialic acid
  • HY-150524

    Endogenous Metabolite P2Y Receptor Metabolic Disease
    UDP-Galactose is a monosaccharide and a key glycosyl donor molecule in cells that participates in nucleotide sugar metabolism. UDP-Galactose is the natural agonist of the P2Y14 receptor coupled to Gi proteins in the immune system (IC50 = 0.67 μM, hP2Y14). UDP-Galactose can be used to study cell signal transduction and substance metabolism .
    UDP-Galactose
  • HY-156905

    Biochemical Assay Reagents Others
    6-Azido-N-acetylgalactosamine-UDP (Compound 5) is a 6-azido-modified nucleotide sugar. It acts as an active sugar donor in lactose glycosylation catalyzed by beta-1,3-N-Acetylhexaminyltransferase (LgtA). Azido-modified nucleotide sugars are strategically used in copper-free click chemistry to modify the N-glycan core structure of IgG .
    6-Azido-N-acetylgalactosamine-UDP
  • HY-N2024R

    Reference Standards Endogenous Metabolite Glycosidase Metabolic Disease
    Maltose (Standard) is the analytical standard of Maltose. This product is intended for research and analytical applications. Maltose is a disaccharide composed of two glucose molecules linked together. Maltose is an endogenous metabolic product in plants, yeast, or bacteria, and it participates in carbon source storage and metabolism. Maltose is a key core metabolite and main transport form in the temporary starch degradation, carbon output, and subsequent sucrose synthesis metabolism of the night chloroplast. In X. dendrorhous, maltose can act as a sugar donor and is converted into isomaltulose by α-glucosidase (α-Glucosidase). Maltose can act as a osmotic agent, supporting continuous capillary ultrafiltration and preventing severe metabolic disorders.
    Maltose (Standard)
  • HY-E70138

    EC:2.4.1.133; B4GALT7

    Glycosyltransferase Others
    β-1,4-Galactosyltransferase 7 has exclusive specificity for the donor substrate UDP-galactose and all transfer galactose in a β-1,4 linkage to similar acceptor sugars: GlcNAc, Glc, and Xyl. .
    β-1,4-Galactosyltransferase 7
  • HY-E70132

    Endo D

    Glycosidase Metabolic Disease
    Endo-β-N-acetylglucosaminidase D (Endo D), isolated from Streptococcus pneumoniae. Endo-β-N-acetylglucosaminidase D hydrolyzes Fc N-glycan of intact IgG antibodies after sequential removal of the sialic acid, galactose, and internal GlcNAc residues in the N-glycan. Endo-β-N-acetylglucosaminidase D possesses transglycosylation activity with sugar oxazoline as the donor substrate .
    Endo-β-N-acetylglucosaminidase D
  • HY-148596

    UDP-N-Acetyl-D-glucosamine; Uridine diphospho-N-acetylglucosamine; UDP-N-acetylglucosamine

    Endogenous Metabolite P2Y Receptor Drug Intermediate Glycosyltransferase Infection
    UDP-GlcNAc (UDP-N-Acetyl-D-glucosamine) is an important component and precursor of bacterial peptidoglycan. UDP-GlcNAc is a nucleotide sugar used by Glycosyltransferases to synthesize glycoproteins, glycosaminoglycans, glycolipids, and glycoRNA. UDP-GlcNAc also serves as the donor substrate for forming O-GlcNAc, a dynamic intracellular protein modification involved in diverse signaling and disease processes. UDP-GlcNAc is the sugar nucleotide donor for the synthesis of O-GlcNAc modified proteins. UDP-GlcNAc also acts as a full agonist of the P2Y14 receptor and inhibits the formation of cAMP. UDP-GlcNAc can be used in studies related to bacterial infections .
    UDP-GlcNAc
  • HY-N2024AS

    Isotope-Labeled Compounds Endogenous Metabolite Glycosidase Metabolic Disease
    Maltose monohydrate-d14 is the deuterium labeled Maltose monohydrate. Maltose monohydrate is a disaccharide composed of two glucose molecules linked together. Maltose monohydrate is an endogenous metabolic product in plants, yeast, or bacteria, and it participates in carbon source storage and metabolism. Maltose monohydrate is a key core metabolite and main transport form in the temporary starch degradation, carbon output, and subsequent sucrose synthesis metabolism of the night chloroplast. In X. dendrorhous, maltose can act as a sugar donor and is converted into isomaltulose by α-glucosidase. Maltose monohydrate can act as a osmotic agent, supporting continuous capillary ultrafiltration and preventing severe metabolic disorders.
    Maltose monohydrate-d14
  • HY-N2024B

    Endogenous Metabolite Glycosidase Metabolic Disease
    Maltose solution, 20% in H2O is a 20% aqueous maltose solution. Maltose is a disaccharide composed of two glucose molecules linked together. Maltose is an endogenous metabolic product in plants, yeast, or bacteria, and it participates in carbon source storage and metabolism. Maltose is a key core metabolite and main transport form in the temporary starch degradation, carbon output, and subsequent sucrose synthesis metabolism of the night chloroplast. In X. dendrorhous, maltose can act as a sugar donor and is converted into isomaltulose by α-glucosidase. Maltose can act as a osmotic agent, supporting continuous capillary ultrafiltration and preventing severe metabolic disorders .
    Maltose solution, 20% in H2O
  • HY-W400427

    Biochemical Assay Reagents Others
    α-D-Glucose-1-phosphate is an important intermediate in sugar metabolism, functioning as a glycosyl donor in glycosyl transfer reactions and participating in glycogen synthesis and degradation through the action of phosphorylases .
    α-D-Glucose-1-phosphate
  • HY-N11102

    dTDP-L-Rhamnose

    Endogenous Metabolite Bacterial Infection
    Thymidine-5'-diphosphate-L-rhamnose (dTDP-L-Rhamnose) is a key activated nucleotide sugar in bacteria, with a KD value of 13 μM for Listeria monocytogenes RmlT. Thymidine-5'-diphosphate-L-rhamnose acts as a high-energy donor for L-Rhamnose (HY-N1420), and is specifically used for the synthesis of bacterial cell wall polysaccharides, capsules and virulence factors .
    Thymidine-5'-diphosphate-L-rhamnose
  • HY-114364S

    Isotope-Labeled Compounds Others
    UDP-α-D-Galactose- 13C disodium is the 13C labeled UDP-α-D-Galactose disodium. UDP-Galactose disodium is a monosaccharide and a key glycosyl donor molecule in cells that participates in nucleotide sugar metabolism. UDP-Galactose disodium is the natural agonist of the P2Y14 receptor coupled to Gi proteins in the immune system (IC50 = 0.67 μM, hP2Y14). UDP-Galactose disodium can be used to study cell signal transduction and substance metabolism .
    UDP-α-D-Galactose-13C disodium
  • HY-145934B

    OGT Biochemical Assay Reagents Glycosidase Metabolic Disease
    UDP-GlcNAz is the analogue of UDP-GlcNAc disodium (HY-112174). UDP-GlcNAc disodium is the donor substrate of many N-acetylgalactosaminyltransferases, enzymes which transfer GlcNAc from the nucleotide sugar to a saccharide or peptide acceptor. UDP-GlcNAc disodium is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups .
    UDP-GlcNAz
  • HY-N11102A

    dTDP-L-Rhamnose disodium

    Endogenous Metabolite Bacterial Infection
    Thymidine-5'-diphosphate-L-rhamnose (dTDP-L-Rhamnose) disodium is a key activated nucleotide sugar in bacteria, with a KD value of 13 μM for Listeria monocytogenes RmlT. Thymidine-5'-diphosphate-L-rhamnose disodium acts as a high-energy donor for L-Rhamnose (HY-N1420), and is specifically used for the synthesis of bacterial cell wall polysaccharides, capsules and virulence factors .
    Thymidine-5'-diphosphate-L-rhamnose disodium
  • HY-N2024AR

    Reference Standards Endogenous Metabolite Glycosidase Metabolic Disease
    Maltose monohydrate (Standard) is the analytical standard of Maltose monohydrate. This product is intended for research and analytical applications. Maltose monohydrate is a disaccharide composed of two glucose molecules linked together. Maltose monohydrate is an endogenous metabolic product in plants, yeast, or bacteria, and it participates in carbon source storage and metabolism. Maltose monohydrate is a key core metabolite and main transport form in the temporary starch degradation, carbon output, and subsequent sucrose synthesis metabolism of the night chloroplast. In X. dendrorhous, maltose can act as a sugar donor and is converted into isomaltulose by α-glucosidase. Maltose monohydrate can act as a osmotic agent, supporting continuous capillary ultrafiltration and preventing severe metabolic disorders.
    Maltose monohydrate (Standard)
  • HY-E70160

    EC:2.4.1.221; POFUT1

    Glycosyltransferase Others
    Protein O-Fucosyltransferase 1 (EC:2.4.1.221; POFUT1) is a Glycosyltransferase containing the cysteine-rich motifs as the acceptor sugar and GDP-fucose as the donor .
    Protein O-Fucosyltransferase 1
  • HY-156905A

    Biochemical Assay Reagents Cancer
    6-Azido-N-acetylgalactosamine-UDP diammonium (compound 5) is an active sugar donor in the beta-1, 3-N-Acetylhexaminyltransferase (LgtA)-catalyzed glycosylation of lactose .
    6-Azido-N-acetylgalactosamine-UDP diammonium
  • HY-N2024AS2

    Isotope-Labeled Compounds Endogenous Metabolite Glycosidase Metabolic Disease
    Maltose monohydrate- 13C is the 13C labeled isotope of Maltose monohydrate. Maltose monohydrate is a disaccharide composed of two glucose molecules linked together. Maltose monohydrate is an endogenous metabolic product in plants, yeast, or bacteria, and it participates in carbon source storage and metabolism. Maltose monohydrate is a key core metabolite and main transport form in the temporary starch degradation, carbon output, and subsequent sucrose synthesis metabolism of the night chloroplast. In X. dendrorhous, maltose can act as a sugar donor and is converted into isomaltulose by α-glucosidase. Maltose monohydrate can act as a osmotic agent, supporting continuous capillary ultrafiltration and preventing severe metabolic disorders.
    Maltose monohydrate-13C

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