UDP-xylose
Based on 2 publication(s) in Google Scholar
UDP-xylose is an endogenous sugar nucleotide and a catalytic substrate of UDP-xylose synthase (UXS). UDP-xylose is a sugar donor for the synthesis of glycoproteins, polysaccharides, various metabolites and oligosaccharides in plants, vertebrates and fungi, and participates in the synthesis of proteoglycans as a glycosyl donor. UDP-xylose participates in the regulation of the synthesis of extracellular matrix components and can be used to study the mechanism of proteoglycan biosynthesis in glycobiology and related diseases (such as connective tissue diseases)[1][2].
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- CAS No.: 3616-06-6
- Formula: C14H22N2O16P2
- Molecular Weight:536.28
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) UDP-xylose
MoreAll Endogenous Metabolite Isoforms
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Biological Activity
UDP-xylose can be generated from UDP-Glc in recombinant yeast cytoplasmic extracts catalyzed by AtUGD1 and AtUXS3[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 3616-06-6
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Molecular Weight 536.28
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Formula C14H22N2O16P2
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SMILES
O[C@H]([C@H]([C@@H](CO1)O)O)[C@H]1OP(OP(OC[C@@H]2[C@@H](O)[C@@H](O)[C@H](N3C(NC(C=C3)=O)=O)O2)(O)=O)(O)=O
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Structure Classification
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Initial Source
Cryptococcus laurentii (N RRL Y-1401)
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (2)
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Journal Impact Factor
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Most Recent
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Mol Plant
2025 Dec 13:S1674-2052(25)00435-6. PMID: 41392480 -
bioRxiv
Biochemical and structural characterization of glycosyltransferase family 61 proteins reveal a key determinant of sugar donor specificity. [Abstract]2025 Jul 19:2025.07.18.665579. PMID: 40791416
Purity & Documentation
References
[1]. Oka T, et al. Reconstruction of de novo pathway for synthesis of UDP-glucuronic acid and UDP-xylose from intrinsic UDP-glucose in Saccharomyces cerevisiae. FEBS J. 2006 Jun;273(12):2645-57. [Content Brief]
[2]. Eixelsberger T, et al. Structure and mechanism of human UDP-xylose synthase: evidence for a promoting role of sugar ring distortion in a three-step catalytic conversion of UDP-glucuronic acid. J Biol Chem. 2012 Sep 7;287(37):31349-58. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
UDP-xylose Related Classifications
HY-N11287 Related Classifications
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