2. Autophagy Metabolic Enzyme/Protease
  3. Autophagy Endogenous Metabolite
  4. Taurine

タウリン  (Synonyms: Taurine)

製品番号: HY-B0351 純度: 99.88%
COA 取扱説明書 Technical Support

Taurine, a sulphur-containing amino acid and an organic osmolyte involved in cell volume regulation, provides a substrate for the formation of bile salts, and plays a role in the modulation of intracellular free calcium concentration. Taurine has the ability to activate autophagy in adipocytes.

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研究用途以外に使用した場合、当社は一切の責任を負いかねます。

CAS 番号 : 107-35-7

容量 価格（税別） 在庫状況 数量
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in Water
ready for reconstitution
 USD 55 在庫あり
Solution
10 mM * 1 mL in Water USD 55 在庫あり
Solid
500 mg $50 在庫あり
1 g $60 在庫あり
5 g $72 在庫あり
10 g $80 在庫あり
25 g $96 在庫あり
50 g $106 在庫あり
100 g $117 在庫あり
500 g $234 在庫あり
> 100 g   お問い合わせ  

* アイテムを追加する前、数量をご選択ください

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カスタマーレビュー

Based on 17 publication(s) in Google Scholar

Other Forms of Taurine:

タウリン 関連抗体

Top Publications Citing Use of Products

    Taurine purchased from MedChemExpress. Usage Cited in: EMBO J. 2025 Nov 20.  [Abstract]

    LDH release from NLRP6-WTtg HIEC-6 cells induced or not with 1 μg/ml doxycycline overnight and infected with WT or Δhly L. monocytogenes EGD for 8 h or treated with 70 mM Taurine.

    Taurine purchased from MedChemExpress. Usage Cited in: Free Radic Biol Med. 2025 Apr 3:S0891-5849(25)00207-2.  [Abstract]

    CCK-8 assay assessing PC12 cell viability after Taurine (TA, 40-120 mM; 24-72 h) treatment at various concentrations for 24 h (A), 48 h (B), and 72 h (C).

    Taurine purchased from MedChemExpress. Usage Cited in: Free Radic Biol Med. 2022 Nov 20;193(Pt 2):795-807.  [Abstract]

    Taurine (400 mg/kg; i.p. 30 min before and 12 h after SAH). Bar graphs showed mortality rates at 24 h after subarachnoid hemorrhage (SAH) in mice.

    Taurine purchased from MedChemExpress. Usage Cited in: Free Radic Biol Med. 2022 Nov 20;193(Pt 2):795-807.  [Abstract]

    Taurine (400 mg/kg; i.p. 30 min before and 12 h after SAH). Western blotting images and quantitative data of relative expression level of ZO-1 and occludin in cerebral cortex at 24 h after subarachnoid hemorrhage (SAH) (n = 4/group).

    Taurine purchased from MedChemExpress. Usage Cited in: Free Radic Biol Med. 2022 Nov 20;193(Pt 2):795-807.  [Abstract]

    The viability of HT22 treated by different concentration of Taurine (5-20 mM) for 24 h was tested by CCK-8 assay in vitro (n = 6/group).

    Endogenous Metabolite アイソフォーム固有の製品をすべて表示:

    すべてのアイソフォームを表示
    Human Endogenous Metabolite Microbial Metabolite

    • 生物活性

    • 純度とドキュメンテーション

    • 参考文献

    • カスタマーレビュー

    製品説明

    Taurine, a sulphur-containing amino acid and an organic osmolyte involved in cell volume regulation, provides a substrate for the formation of bile salts, and plays a role in the modulation of intracellular free calcium concentration. Taurine has the ability to activate autophagy in adipocytes[1][2][3].

    IC50 & Target

    Human Endogenous Metabolite

     

    Cellular Effect
    Cell Line Type Value Description References
    HEK293 EC50
    10 μM
    Compound: 1123
    Substrate uptake by the Taurine Transporter (TauT, SLC6A6) as assessed by the fluorescent FLIPR membrane potential dye in HEK-293 JumpIN-SLC6A6 cells
    Substrate uptake by the Taurine Transporter (TauT, SLC6A6) as assessed by the fluorescent FLIPR membrane potential dye in HEK-293 JumpIN-SLC6A6 cells
    		10.5281/zenodo.7360560
    HEK293 EC50
    10 μM
    Compound: 1123
    Substrate uptake by the Taurine Transporter (TauT, SLC6A6) as assessed by the fluorescent FLIPR membrane potential dye in HEK-293 JumpIN-SLC6A6 cells (PubChem AID: 1794824)
    Substrate uptake by the Taurine Transporter (TauT, SLC6A6) as assessed by the fluorescent FLIPR membrane potential dye in HEK-293 JumpIN-SLC6A6 cells (PubChem AID: 1794824)
    		10.5281/zenodo.7360560
    L6 IC50
    >90 μg/mL
    Compound: 6
    Cytotoxicity against rat L6 cells after 72 hrs
    Cytotoxicity against rat L6 cells after 72 hrs
    		[PMID: 17765547]
    体外実験

    Taurine is one of the most abundant amino acids in the brain and spinal cord, leukocytes, heart and muscle cells, the retina, and indeed almost every tissue throughout the body[1].
    Taurine exhibits diverse biological actions, including protection against ischemia-reperfusion injury, modulation of intracellular calcium concentration, and antioxidant, antiatherogenic and blood pressure-lowering effects[2].

    MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

    タウリン 関連抗体
    臨床実験
    分子量

    125.15

    分子式

    C2H7NO3S
    CAS 番号
    Appearance

    Solid

    Color

    White to off-white

    SMILES

    NCCS(=O)(O)=O
    Structure Classification
    Initial Source
    輸送条件

    Room temperature in continental US; may vary elsewhere.
    保管条件

    Store at room temperature 3 years

    *In solvent : -80°C, 6 months; -20°C, 1 month (Store at room temperature 3 years)
    溶剤 & 溶解度
    体外: 

    H2O : 25 mg/mL (199.76 mM; Need ultrasonic)

    DMSO : 1 mg/mL (7.99 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

    Preparing
    Stock Solutions
    Concentration Solvent Mass 1 mg 5 mg 10 mg
    1 mM 7.9904 mL 39.9521 mL 79.9041 mL
    5 mM 1.5981 mL 7.9904 mL 15.9808 mL
    10 mM 0.7990 mL 3.9952 mL 7.9904 mL
    View the Complete Stock Solution Preparation Table

    * Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
    Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.

    * Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

    • Molarity Calculator

    • Dilution Calculator

    Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

    Mass
    =
    Concentration
    ×
    Volume
    ×
    Molecular Weight *

    Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

    一般には略語で表示されます：C1V1 = C2V2

    濃度 （開始）

    C1

    ×
    体積 （開始）

    V1

    =
    濃度 （終了）

    C2

    ×
    体積 （終了）

    V2

    体内:

    For the following dissolution methods, please prepare the working solution directly. It is recommended to prepare fresh solutions and use them promptly within a short period of time.
    The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

    • Protocol 1

      Add each solvent one by one:  PBS

      Solubility: 12.5 mg/mL (99.88 mM); Clear solution; Need ultrasonic and warming and heat to 60°C

    In Vivo Dissolution Calculator
    Please enter the basic information of animal experiments:

    Dosage

    mg/kg

    Animal weight
    (per animal)

    g

    Dosing volume
    (per animal)

    μL

    Number of animals

    Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
    Calculation results:
    Working solution concentration: mg/mL
    This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
    The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
    純度とドキュメンテーション

    純度: 99.99%

    COA (246 KB) HNMR (129 KB) LCMS (95 KB)

    取扱説明書 (2659 KB)
    参考文献

    Complete Stock Solution Preparation Table

    * Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
    Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.

    Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
    DMSO / H2O 1 mM 7.9904 mL 39.9521 mL 79.9041 mL 199.7603 mL
    5 mM 1.5981 mL 7.9904 mL 15.9808 mL 39.9521 mL
    H2O 10 mM 0.7990 mL 3.9952 mL 7.9904 mL 19.9760 mL
    15 mM 0.5327 mL 2.6635 mL 5.3269 mL 13.3174 mL
    20 mM 0.3995 mL 1.9976 mL 3.9952 mL 9.9880 mL
    25 mM 0.3196 mL 1.5981 mL 3.1962 mL 7.9904 mL
    30 mM 0.2663 mL 1.3317 mL 2.6635 mL 6.6587 mL
    40 mM 0.1998 mL 0.9988 mL 1.9976 mL 4.9940 mL
    50 mM 0.1598 mL 0.7990 mL 1.5981 mL 3.9952 mL
    60 mM 0.1332 mL 0.6659 mL 1.3317 mL 3.3293 mL
    80 mM 0.0999 mL 0.4994 mL 0.9988 mL 2.4970 mL
    100 mM 0.0799 mL 0.3995 mL 0.7990 mL 1.9976 mL

    * Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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    Taurine Related Classifications

    • Molarity Calculator

    • Dilution Calculator

    The molarity calculator equation

    Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

    質量   濃度   体積   分子量 *
    = × ×

    The dilution calculator equation

    Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

    一般には略語で表示されます：C1V1 = C2V2

    濃度 （開始） × 体積 （開始） = 濃度 （終了） × 体積 （終了）
    × = ×
    C1   V1   C2   V2
    Help & FAQs
    • Do most proteins show cross-species activity?

      Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

    Keywords:

    Taurine107-35-72-Aminoethanesulfonic acidAutophagyEndogenous Metaboliteantioxidantantiatherogenicbloodpressure-loweringcardiovascularbilesaltsInhibitorinhibitorinhibit

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    製品名:
    Taurine
    製品番号:
    HY-B0351
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